• Asian Pacific Journal of Cancer Prevention
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• v.13 no.1
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• pp.195-198
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• 2012

To date, there was no controlled-study regarding awareness and knowledge of colorectal cancer in the Turkish population. We therefore designed a questionnaire consisting of items related to socio-demographic parameters, medical and family history and questions of awareness and knowledge about colorectal cancer for use in a descriptive cross-sectional study. An interviewer-administered technique was applied and 450 subjects were interviewed in the outpatient clinics at Near East University Hospital. Among all subjects, 337 were found to be eligible for the study group. Exclusion criteria were age below 18 years, any cancer history, family history of colorectal cancer, current colorectal problems, history of any diagnostic or therapeutic interventions for colorectal diseases. All participants stated that they heard about colorectal cancer. When asked about the lifetime risk of colorectal carcinoma, only 25.4% of women and 37.9% of men estimated correctly. Univariate analysis revealed that the total awareness score was significantly correlated with age, marital status, parenthood and fecal occult blood testing history. On multivariate analysis of independent predictors for awareness of colorectal cancer were found to be history of fecal occult blood testing, age and marital status were found to be the most important determinants. As a conclusion, opportunistic screening with fecal occult blood test by physicians from non-gastrointestinal specialties not only helps to reduce the mortality but also increases the awareness of colorectal cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.715-718
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• 2012

The current research concerns the clinicopathological significance of MHC class I chain-related protein A (MICA) expression in oral squamous cell carcinomas (OSCCs). The expression and location of MICA protein in 14 normal oral mucous and 45 cancerous and para-cancerous tissues were assessed by immunohistochemistry and levels of MICA mRNA expression in 29 cancerous and para-cancerous tissues were determined by the real-time polymerase chain reaction. Data were analyzed with the SPSS16.0 software package. MICA was found to be located in the cytoplasm and plasma membrane. Expression was higher in para-cancerous than in cancerous tissues (P < 0.05). However, no statistical difference was found between the following: 1) para-cancerous tissue with normal mucosa; 2) normal mucosa with cancerous tissue;and 3) among different clinicopathological parameters in OSCC (P > 0.05). The level of MICA mRNA was higher in OSCCs than in para-cancerous tissues, and was correlated with the regional lymph node status and disease stage (P < 0.05). The levels of MICA protein and mRNA expression differ among normal oral mucosa, para-cancerous tissue, and cancerous tissue. MICA may contribute to the tumorigenesis and progression of OSCC.

• Geomechanics and Engineering
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• v.15 no.5
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• pp.1091-1100
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• 2018

In this study, the relationships between hydraulic conductivity of GCLs and physico-chemical properties of bentonites were assessed. In addition to four factory manufactured GCLs, six artificially prepared GCLs (AP-GCLs) were tested. AP-GCLs were prepared in the laboratory without bonding or stitching. A total of 20 hydraulic conductivity tests were conducted using flexible wall permeameters ten of which were permeated with distilled deionized water (DIW) and the rest were permeated with tap water (TW). The hydraulic conductivity of GCLs and AP-GCLs were between $5.2{\times}10^{-10}cm/s$ and $3.0{\times}10^{-9}cm/s$. The hydraulic conductivities of all GCLs to DIW were very similar to that of GCLs to TW. Then, simple regression analyses were conducted between hydraulic conductivity and physicochemical properties of bentonite. The best correlation coefficient was achieved when hydraulic conductivity was related with clay content (R=0.85). Liquid limit and plasticity index were other independent variables that have good correlation coefficients with hydraulic conductivity (R~0.80). The correlation coefficient with swell index is less than other parameters, but still fairly good (R~0.70). In contrast, hydraulic conductivity had poor correlation coefficients with specific surface area (SSA), smectite content and cation exchange capacity (CEC) (i.e., R < 0.5). Furthermore, some post-test properties of bentonite such as final height and final water content were correlated with the hydraulic conductivity as well. The hydraulic conductivity of GCLs had fairly good correlation coefficients with either final height or final water content. However, those of AP-GCLs had poor correlations with these variables on account of fiber free characteristics.

• Korean Journal of Materials Research
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• v.20 no.6
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• pp.319-325
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• 2010

3-D IC integration enables the smallest form factor and highest performance due to the shortest and most plentiful interconnects between chips. Direct metal bonding has several advantages over the solder-based bonding, including lower electrical resistivity, better electromigration resistance and more reduced interconnect RC delay, while high process temperature is one of the major bottlenecks of metal direct bonding because it can negatively influence device reliability and manufacturing yield. We performed quantitative analyses of the interfacial properties of Al-Al bonds with varying process parameters, bonding temperature, bonding time, and bonding environment. A 4-point bending method was used to measure the interfacial adhesion energy. The quantitative interfacial adhesion energy measured by a 4-point bending test shows 1.33, 2.25, and $6.44\;J/m^2$ for 400, 450, and $500^{\circ}C$, respectively, in a $N_2$ atmosphere. Increasing the bonding time from 1 to 4 hrs enhanced the interfacial fracture toughness while the effects of forming gas were negligible, which were correlated to the bonding interface analysis results. XPS depth analysis results on the delaminated interfaces showed that the relative area fraction of aluminum oxide to the pure aluminum phase near the bonding surfaces match well the variations of interfacial adhesion energies with bonding process conditions.

• Journal of the Korean earth science society
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• v.30 no.7
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• pp.810-823
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• 2009

One of the critical factors in accurate determination of earthquake source parameters, and in prediction of seismic hazards is the detailed information related to the site amplification characteristics. The site amplification characteristics of the broad-band seismic stations in Korea were estimated as a function of frequency in the range of 0.2 to 20 Hz. A total of 1275 seismograms recorded from 43 earthquakes observed from 2003 to 2008 in the southern Korean Peninsula were used. It was found that the site amplification ratios for 28 stations estimated from the inversion of the ground motion model were approximately concordant with those obtained from the horizontal-to-vertical (H/V) spectral ratio except for some stations. The spectral site amplification characteristics obtained in this study did not show any considerable spatial distribution. It revealed to be largely correlated with the degree of weathering rather than the basement rock type. Considering the spectral site amplification ratio, 28 broad-band stations were classified into four groups and the characteristics of each group were described in the text.

• Journal of Korea Water Resources Association
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• v.37 no.12
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• pp.1065-1074
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• 2004

This study aims at the introduction of new catchment shape descriptor, developed by Moussa(2003), based on equivalent ellipse and the assessment of its hydrologic applicability. Two descriptors a+b and a+b+${\varepsilon}OM$were correlated to the lag time and those were applied to the estimation of representative values of Nash model parameters. They are applied in order to examine the practicality to 3 catchments in Korea, catchments in Korea, respectively, i.e. Pyeongchanggang catchment in Han river, Bocheongcheon catchment in Geum river and Wicheon catchment in Nakdong river. As a result both of two descriptors show higher correlations to the lag lime than classical geomorphologic factors and hereby Moussa's suggestion(2003) is confirmed. For the sake of simplicity the former is recommended. Also representative IUHs derived from this study show consistent basin response characteristics. It is desirable to conduct further more case studies on many other basins.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.41.1-41.1
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• 2013

To test whether the close relationships between host and satellite galaxies in isolated groups are also found in the harsh environment of a galaxy cluster, we carry out a case study of WHL 085910.0+294957, a galaxy cluster at z=0.30, using deep images obtained with the 2.1-m Otto Struve telescope and CQUEAN CCD camera. When environmental parameters are controlled, the local weighted mean color of faint galaxies shows a measurable correlation with the color of their bright ($M_i$ < -18) neighbor. The most striking result is that the red (r - i > 0.2) and bright galaxies within 200 kpc distance from the center of the cluster are correlated in color with very faint ($M_i$ > -14) galaxies around them by $(r-i)_{satellites}=(7.276{\pm}1.402){\times}(r-i)_{host}-2.434$ (correlation coefficient = 0.665). We suggest three scenarios to interpret the results: vestiges of infallen groups, dwarf capturing, and tidal tearing of bright galaxies.

• KSBB Journal
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• v.4 no.1
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• pp.34-39
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• 1989

Growth kinetics of mammalian cell, Chinese Hamster Ovalry(CHO) was investigated to effectively produce pharmaceutically important Erythropoeitin under perfusion chemostat conditions. Perfusion rate, D is correlated with total viable is to be an essential factor in controlling growth kinetic parameters under this kind of operations. It is also found that the measurement of oxygen uptake rates is a relatively accurate method to understand cell growth, in case that the traditional cell count method is no longer useful due to heavy cell clumpings. True growth yield, Ymax and maintenance coefficient, me associated with mammalian cell growth were estimated as $2.86{\times}10^8$ cells/ g of glucose and 0.0063 g of glucose/ cells/ hr, respectively.

• Horticultural Science & Technology
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• v.34 no.5
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• pp.677-691
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• 2016

To assess South Korean commercial tomato cultivars, regular and cherry tomato cultivars were grown in the greenhouse and evaluated for color attributes, titratable acidity, pH, total soluble solids, carotenoids (lycopene and ${\beta}$-carotene), total phenols, flavonoids, vitamin C, and antioxidant activity. Significant differences (p < 0.05 using Duncan's multiple range test (DMRT)) were observed in the levels of most phytochemicals, quality parameters, and antioxidant activity among the twenty South Korean tomato cultivars tested. Lycopene and ${\beta}$-carotene contents varied significantly (p < 0.05 using DMRT), from $0.95mg{\cdot}100g^{-1}$ to $5.12mg{\cdot}100g^{-1}$ and $0.65mg{\cdot}100g^{-1}$ to $3.56mg{\cdot}100g^{-1}$ of fresh weight, respectively. ${\beta}$-carotene contents exhibited the highest genetic variation (59.2%), followed by naringenin (52.8%) and other phytochemicals. Most of the cherry tomato cultivars had statistically higher levels (p < 0.05 using DMRT) of carotenoids, phenols, flavonoids, vitamin C, and antioxidant activity compared to the regular tomato varieties, suggesting their higher nutritional value. Lycopene content was highest in the cultivars YoYo, Jicored, Titi-Chal, TY-Endorphin, and Rubyking. Cultivars Rubyking, TY-Endorphin, and Titi-Chal also showed relatively higher antioxidant activities in three assays: 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and ferric ion reducing antioxidant power (FRAP) assays. All the antioxidants, except luteolin, were positively correlated with antioxidant activities; the highest correlation was observed between total phenol and antioxidant activities, followed by the correlation between rutin and vitamin C. Cultivars identified to have superior nutritional status would be useful in tomato breeding programs to further improve quality and health benefits of tomatoes for the fresh and processed markets.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.9
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• pp.4287-4306
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• 2016

Network resilience provides an effective way to overcome the problem of network failure and is crucial to Internet protocol (IP) network management. As one of the main challenges in network resilience, recovering from link failure is important to maintain the constancy of packets being transmitted. However, existing failure recovery approaches do not handle the traffic engineering problem (e.g., tuning the routing-protocol parameters to optimize the rerouting traffic flow), which may cause serious congestions. Moreover, as the lack of QoS (quality of service) restrictions may lead to invalid rerouting traffic, the QoS requirements (e.g., bandwidth and delay) should also be taken into account when recovering the failed links. In this paper, we first develop a probabilistically correlated failure model that can accurately reflect the correlation between link failures, with which we can choose reliable backup paths (BPs). Then we construct a mathematical model for the failure recovery problem, which takes maximum rerouting traffic as the optimizing objective and the QoS requirements as the constraints. Moreover, we propose a heuristic algorithm for link failure recovery, which adopts the improved k shortest path algorithm to splice the single BP and supplies more protection resources for the links with higher priority. We also prove the correctness of the proposed algorithm. Moreover, the time and space complexity are also analyzed. Simulation results under NS2 show that the proposed algorithm improves the link failure recovery rate and increases the QoS satisfaction rate significantly.