• 비교문화연구
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• 제29권
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• pp.453-477
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• 2012

This study investigates how the truth-related words in Korean, which were originally noun or adverb with 'truth' related meaning, can be used as discourse markers with the functions such as 'emphatic marker', 'attention getter', or 'hesitation marker', and it argues that such functions of the discourse markers are the result of grammaticalization process. That is to say that the truth-related words have acquired new functions as discourse markers from their corresponding lexical items as a noun or an adverb through grammaticalization process. In this study, we demonstrate that the truth-related words tend to appear sentence-initially or sentence-medially when they are used as discourse markers. We also show that they are most likely to be used as emphatic marker because of the lexical meaning of the truth-related words. Finally, we state that truth-related words differ from one another in where they appear and what function they are used with.

• 중국학논총
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• 제65호
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• pp.23-38
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• 2020

The dictionary is the most important tool for every Chinese learner to confirm the meaning and usage of words. Therefore, accuracy of headword's interpretation in the dictionary is crucial. This study aims to discuss the accuracy and the adequacy of headwords' interpretation in the Chinese-Korean dictionary through the Chinese corpus and Baidu. The scope of this study are 3000 words in the D3H1 region. According to the research results, the main problems of the vocabulary in this region can be divided into three categories: the first is the problem of lexical interpretation, the second is the problem of missing interpretation, and the third is other problems. In the D3H1 area, there are a total of 719 low-frequency vocabularies, and 54 headword's interpretations are not accurate or appropriate. This study is a detailed investigation and analysis of the problems of these 54 vocabularies.

• 말소리와 음성과학
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• 제5권1호
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• pp.123-130
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• 2013

Previous researches on Korean intonation have been mainly focused on $F_0$ target frequencies, $F_0$ slope, and the duration of intonation patterns. This study investigated Korean intonation patterns, both boundary and phrasal tones, in relation to the $F_0$ percentage change between pitch targets. We measured the percentage change between the pitch targets of both boundary and phrasal tones. Additionally, the $F_0$ change between the preceding pitch target and the first pitch target of the boundary tone and the $F_0$ targets of the sequence of two LH phrasal tones ('LH + LH') were also measured. Two phrasal tones, LHLH and HLH, were compared with 'LH + LH' and the 'HLH' in the LHLH pattern respectively. We found that the percentage change between pitch targets in the phrasal tone is fixed to some extent. This helped explain why the slope of the phrasal tone is closely related to the number of syllables and the duration of the phrasal tone as discussed in previous studies. Since we analyzed the intonation patterns with the utterances from a large speech corpus, the results of this paper are expected to be used in building a larger annotated corpus of Korean.

• 동의생리병리학회지
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• 제27권6호
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• pp.809-817
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• 2013

The aim of this study was to evaluate the mechanism of vasodilation of Lespedezea cuneata(LC) in rabbit common carotid artery and cavernosal smooth muscle. LC relaxed arterial strips precontracted with norepinephrine and cavernosal strips precontracted with phenylephrine. The arterial relaxation effects of LC was endothelium-dependent. $N{\omega}$-nitro-L-arginine(L-NNA), NOS inhibitor, methylene blue(MB), cGMP inhibitor, indomethacin(IM), cyclo-oxygenase inhibitor and tetraethylammonium chloride(TEA), KCa-channel blocker attenuate the relaxation responses of LC in arterial strips. In $Ca^{2+}$-free krebs-ringer solution, pretreatment of LC extract significantly reduced the contraction induced by addition $Ca^{2+}$. L-NNA reduced LC extract-induced relaxation in cavernosal strips, but IM, TEA and MB didn't affect LC extract-induced relaxation. When LC extract was applicated on human umbilical vein endothelial cell, the nitric oxide concentration was increased. We conclude that in rabbit common carotid artery, LC may suppress influx of extra-cellular $Ca^{2+}$ through the release of endothelium derived relaxing factor including nitric oxide, prostacyclin, endothelium derived hyperpolarizing factor. And LC exerts a relaxing effect on corpus cavernosum through activating the NO.

• 국제물리치료학회지
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• 제3권2호
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• pp.429-434
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• 2012

Ischemia, the leading cause of strokes, is known to be deeply related to synaptic plasticity and apoptosis in tissue damage due to ischemic conditions or trauma. The purpose of this study was to research the effects of NEES(needle electrode electrical stimulation) in brain cells of ischemia-induced rat, more specifically the effects of Poly[ADP-ribose] polymerase(PARP) on the corpus striatum. Ischemia was induced in SD mice by occluding the common carotid artery for 5 minutes, after which blood was re-perfused. NEES was applied to acupuncture points, at 12, 24, and 48 hours post-ischemia on the joksamri, and at 24 hours post-ischemia on the hapgok. Protein expression was investigated through PARP antibody immuno-reactive cells in the cerebral nerve cells and western blotting. The number of PARP reactive cells in the corpus striatum 24 hours post-ischemia was significantly(p<.05) smaller in the NEES group compared to the global ischemia(GI) group. PARP expression 24 hours post-ischemia was very significantly smaller in the NEES group compared to the GI group. Results show that ischemia increases PARP expression and stimulates necrosis, making it a leading cause of death of nerve cells. NEES can decrease protein expression related to cell death, protecting neurons and preventing neuronal apoptosis.

• Mycobiology
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• 제48권2호
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• pp.153-156
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• 2020

Calvatia nipponica, a puffball mushroom (Agaricaceae), is thought to be an aphrodisiac, as this mushroom is traditionally known to improve sexual function in males. As part of the systematic study to determine the bioactive secondary metabolites from C. nipponica responsible for aphrodisiac effects, chemical analysis of methanol (MeOH) extracts of the fruiting bodies of C. nipponica resulted in the isolation of two major compounds: N,N-dimethyl-anthranilic acid (1) and (7Z,10Z)-7,10-octadecadienoic acid methyl ester (2). Compounds 1 and 2 were evaluated for cumulative dose-dependent relaxation responses to precontracted penile corpus smooth muscle (PCCSM). Results show that compounds 1 and 2 exhibited a maximum relaxation effect of 20.33 ± 2.18% and 24.63 ± 3.60%, respectively. These findings indicate that compounds 1 and 2, major components of C. nipponica, could potentially be used to treat erectile dysfunction, functioning as natural aphrodisiacs.

• 한국동물학회지
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• 제33권2호
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• pp.152-157
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• 1990

면역조직화학적 방법을 이용하여 생쥐 난소에서 $\beta$-endorphin이 생성되는 부위를 조사하기 위하여 본 실험을 행하였다. 성숙한 생쥐를 4% neutral buffered paraformaldehyde로 관류고정하였으며 난소를 적출한 후 cryostat로 절편을 만들어 avidin-biotin complex(ABC)를 이용하여 면역색을 하였다. $\beta$-endorphin에 대한 항체반응은 주로 황체에서 일어났으며, theac interna와 theca externa에서는 반응이 나타나지 않았다. 황체에서의 염색 양상은 퇴화가 많이 진행된 황체세포에서 보다 강한 연색반응을 관찰할 수 있었다. 때로 황체세포에서 유래된 것으로 보이는 간질세포에서도 양성반응을 관찰할 수 있었다. 이외에도 large antral follicle의 여포강에 인접한 과립세포에서 약한 반응을 보여주었으나, 제 1차 여포에서는 양성반응이 나타나지 않았다.

• Biomolecules & Therapeutics
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• 제11권4호
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• pp.232-237
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• 2003

The present study examined functional effects of a new selective phosphodiesterase type 5 inhibitor, 1-[4-ethoxy-3-(6,7-dihydro-1-methyl-7-thioxo-3-propyl-1H-pyrazolo[ 4,3]pyrimidin-5-yl)phenylsulphonyl]-4-methyl piperazine (KJH-1002), in the isolated rabbit corpus cavernosum (RCC). Relaxing effects of KJH-1002 were also compared with those of sildenafil, which is currently used as an oral therapy for penile erectile dysfunction. In the isolated RCC precontracted with phenylephrine, both KJH-1002 and sildenafil in the concentration range of 1 to 1000 nM, produced a comparable potentiation of the electical field stimulation-induced relaxation in a concentration-dependent manner. In the sodium nitroprusside (SNP)-induced relaxation, the $IC_{50}$/ values, concentrations of SNP required to produce a 50％ relaxation of the phenylephrine-induced contraction, were significantly decreased to the similar extent by treatments with KJH-1002 and sildenafil. The results suggest that a new selective phosphodiesterase type 5 inhibitor, KJH-1002, has an augmentative effect on penile erection comparable to that of sildenafil and can be useful for the treatment of erectile dysfunction.

• 한국어학
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• 제76권
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• pp.83-112
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• 2017

In this paper, newspaper articles were collected through '5.18' keyword search results and the news corpus was constructed from the collected data. In the articles of local newspapers 'Honam' and 'Yeongnam', the ideological differences regarding '5.18' were investigated. The ideological differences of local newspaper discourse through objective figures was analyzed.. The subjects of the newspaper articles, the frequency of nouns and predicates were analyzed. The use and meaning of the intended vocabulary were examined. As a result of analyzing the title of the newspaper article, the discourse written in 'Honam' emphasized the necessity of re - recognition of 5.18. In both regions, the word "Gwangju" is often used. However, 'Gwangju' in 'Honam' newspaper means spiritual space, not physical space. In Honam regional newspapers, there are many vocabularies describing the events such as 'shoot' and 'fire', this calls for recollection and memory of '5.18'. In the analysis of newspaper discourse, the analysis of the contrast between the local newspapers was very insignificant, but, this study was conducted to analyze the discourse among local newspapers.

• 한국어교육
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• 제29권4호
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• pp.255-294
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• 2018

The Buckwheat Season, evaluated as the best of Lee Hyo-seok's literature, is one of the short stories that represent Korean literature. However, vivid literary expressions such as lyrical and beautiful depictions, figurative expressions and dialects, which show the Korean beauty, rather make learners have difficulty and become a factor that fails in reading comprehension. Thus, it is necessary to revise and present the text modified for the learners' language level. The methods of revising a literary text include the revision of linguistic elements such as cryptic vocabulary or sentence structure and the revision of the composition of the text, e.g. suggestion of characters or plot, or insertion of illustration. The methods of revising the language of the text can be divided into methods of simplification and detailing. However, in the process of revising the text, many depend on the adapter's subjective perception, not revising it with objective criteria. This paper revised the text, utilizing by the Academy of Korean Studies, , and the by the National Institute of Korean Language to secure objectivity in revising the text.