• 제목/요약/키워드: corporation

검색결과 13,291건 처리시간 0.038초

The Inhibitory Effect of New Hydroxamic Acid Derivatives on Melanogenesis

  • Baek, Heung-Soo;Rho, Ho-Sik;Yoo, Jae-Won;Ahn, Soo-Mi;Lee, Jin-Young;Lee, Jeong-A;Kim, Min-Kee;Kim, Duck-Hee;Chang, Ih-Seop
    • Bulletin of the Korean Chemical Society
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    • 제29권1호
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    • pp.43-46
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    • 2008
  • The aim of present study was to examine the inhibitory effects of hydroxamic acid derivatives on the melanogenesis. We found that hydroxamic acid moiety was important for anti-melanogenic activity. Compounds 1a and 1b strongly inhibited melanin synthesis via deactivation of tyrosinase. Hydroxamic acid has metal ion chelating ability which is similar to that kojic acid, however, anti-tyrosinase mechanism of compounds 1a and 1b was different from that of kojic acid. They showed noncompetitive inhibition kinetics

Qualification of liquid crystal mixtures by bulk-state transient current analysis

  • Peng, Kang-Yung;Yin, Hsueh-Min;Lin, Yang-Chu;Wang, Yang-Long;Kung, Li-Wei;Chan, Meng-Xi;Cheng, Hsin-An;Liau, Wei-Lung;Lien, Alan
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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    • pp.855-858
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    • 2008
  • Transient current (TC) on bulk-state liquid crystal mixtures was measured. We found that TC is very sensitive to impurities and the features of TC curves depend on the type of contamination, from which the quality of materials can be definitely evaluated and the type of impurities can also be revealed.

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Blazed $GxL^{TM}$ Device for Laser Dream Theater at the Aichi Expo 2005

  • Ito, Yasuyuki;Saruta, Kunihiko;Kasai, Hiroto;Nishida, Masato;Yamaguchi, Masanari;Yamashita, Keitaro;Taguchi, Ayumu;Oniki, Kazunao;Tamada, Hitoshi
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2006년도 6th International Meeting on Information Display
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    • pp.556-559
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    • 2006
  • We successfully developed a high performance and highly reliable blazed GxL device with a high optical efficiency and a high contrast ratio. The device demonstrated superior resistance against a high power laser, which is suitable for a large-area laser projector. We operated the world's largest laser projection screen using this device at the 2005 World Exposition in Aichi, Japan, problem free.

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현행법상 의료법인의 비영리성과 문제점 (Noncommerciality and problem of a medical corporation under the present law)

  • 백경희
    • 의료법학
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    • 제8권2호
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    • pp.291-328
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    • 2007
  • Under the present law, a medical corporation has the legalistic character of a noncommercial corporation and its commerciality is restricted by public service. In a recent precedent, however, a judgment has considered the service part in medical practice. The tendency of a precedent is that both commerciality of a medical institution and medical corporation are allowed to be pursued under fundamental order-observance. This change is found in china and india, which consider a medical service as national industry. In the case of ours, the now government demonstrate the industrialization or the market of medical service through promotion of commerciality of a medical corporation. This paper deal with the meaning of a medical corporation and the present condition of medical market under the present law and recommends a tendency of law policy through study of foreign's and our precedent for commerciality of medical advertisement and medical corporation.

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Large Pre-trained Language Model의 P-tuning을 이용한 질의 정규화 (Query Normalization Using P-tuning of Large Pre-trained Language Model)

  • 서수빈;인수교;박진성;남경민;김현욱;문기윤;황원요;김경덕;강인호
    • 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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    • 한국정보과학회언어공학연구회 2021년도 제33회 한글 및 한국어 정보처리 학술대회
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    • pp.396-401
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    • 2021
  • 초거대 언어모델를 활용한 퓨샷(few shot) 학습법은 여러 자연어 처리 문제에서 좋은 성능을 보였다. 하지만 데이터를 활용한 추가 학습으로 문제를 추론하는 것이 아니라, 이산적인 공간에서 퓨샷 구성을 통해 문제를 정의하는 방식은 성능 향상에 한계가 존재한다. 이를 해결하기 위해 초거대 언어모델의 모수 전체가 아닌 일부를 추가 학습하거나 다른 신경망을 덧붙여 연속적인 공간에서 추론하는 P-tuning과 같은 데이터 기반 추가 학습 방법들이 등장하였다. 본 논문에서는 문맥에 따른 질의 정규화 문제를 대화형 음성 검색 서비스에 맞게 직접 정의하였고, 초거대 언어모델을 P-tuning으로 추가 학습한 경우 퓨샷 학습법 대비 정확도가 상승함을 보였다.

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Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography

  • Park, Hee-Won;In, Gyo;Han, Sung-Tai;Lee, Myoung-Woo;Kim, So-Young;Kim, Kyung-Tack;Cho, Byung-Goo;Han, Gyeong-Ho;Chang, Il-Moo
    • Journal of Ginseng Research
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    • 제37권4호
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    • pp.457-467
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    • 2013
  • A quick and simple method for simultaneous determination of the 30 ginsenosides (ginsenoside Ro, Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, 20(S)-Rg2, 20(R)-Rg2, 20(S)-Rg3, 20(R)-Rg3, 20(S)-Rh1, 20(S)-Rh2, 20(R)-Rh2, F1, F2, F4, Ra1, Rg6, Rh4, Rk3, Rg5, Rk1, Rb3, Rk2, Rh3, compound Y, compound K, and notoginsenoside R1) in Panax ginseng preparations was developed and validated by an ultra performance liquid chromatography photo diode array detector. The separation of the 30 ginsenosides was efficiently undertaken on the Acquity BEH C-18 column with gradient elution with phosphoric acids. Especially the chromatogram of the ginsenoside Ro was dramatically enhanced by adding phosphoric acid. Under optimized conditions, the detection limits were 0.4 to 1.7 mg/L and the calibration curves of the peak areas for the 30 ginsenosides were linear over three orders of magnitude with a correlation coefficients greater than 0.999. The accuracy of the method was tested by a recovery measurement of the spiked samples which yielded good results of 89% to 118%. From these overall results, the proposed method may be helpful in the development and quality of P. ginseng preparations because of its wide range of applications due to the simultaneous analysis of many kinds of ginsenosides.