• Parasites, Hosts and Diseases
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• v.61 no.3
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• pp.231-239
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• 2023

Toxoplasma gondii is an intracellular parasitic organism affecting all warm-blooded vertebrates. Due to the unavailability of commercialized human T. gondii vaccine, many studies have been reported investigating the protective efficacy of pre-clinical T. gondii vaccines expressing diverse antigens. Careful antigen selection and implementing multifarious immunization strategies could enhance protection against toxoplasmosis in animal models. Although none of the available vaccines could remove the tissue-dwelling parasites from the host organism, findings from these pre-clinical toxoplasmosis vaccine studies highlighted their developmental potential and provided insights into rational vaccine design. We herein explored the progress of T. gondii vaccine development using DNA, protein subunit, and virus-like particle vaccine platforms. Specifically, we summarized the findings from the pre-clinical toxoplasmosis vaccine studies involving T. gondii challenge infection in mice published in the past 5 years.

• Macromolecular Research
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• v.9 no.1
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• pp.51-65
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• 2001

Two-stage emulsion polymerizations of hydrophobic monomers on hydrophilic seed polymer particles were carried out to make core-shell composite particles. It was found that the loci of polymerization in the second stage were the surface layer of the hydrophilic seed latex particles, and that it has resulted in the formation of either eccentric core-shell particles with the core exposed to the aqueous phase or aggregated nonspherical composite particles with the shell attached on the seed surface as many small separated particles. The driving force of these phenomena is related to the gain in free energy of the system in going from the hydrophobic polymer-water interface to hydrophilic polymer-water interface. Thermodynamic analysis of the present polymerization system, which was based on spreading coefficients, supported the likely occurrence of such nonspherical particles due to the combined effects of interfacial free energies and phase separation between the two polymer phases. A hypothetical pathway was proposed to prepare hydrophilic core-hydrophobic shell composite latex particles, which is based on the concept of opposing driving and resistance forces for the phase migration. It was found that the viscosity of the monomer-swollen polymer phase played important role in the formation of particle morphology.

• 한국정보디스플레이학회:학술대회논문집
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• 2007.08b
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• pp.1551-1554
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• 2007

To overcome defect due to large surface of nanoparticle, a redispersible Eu doped $LnPO_4:LnPO_4$ core/shell nanoparticles were prepared in a highboiling coordinating solvent. The particle size of the synthesized core/shell nanophosphors was estimated to be about 8 nm by TEM. In this core/shell nanoparticle, the concentration of Eu ion was optimized on the basis of the emission intensity under UV ray excitation. Also, the PL properties of the nanophosphors have been compared with those of the $LnPO_4:Eu$ nanoparticles.

• Journal of the Korean Ceramic Society
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• v.37 no.6
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• pp.524-529
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• 2000

Silica slab wavegudie was fabricated on Si substrates by FHD for planar optical passive devices. The slab waveguide consists of lower clad and core layers, where core layer index is controlled by GeO2 addition. Doping of GeO2 in silica is difficult because of the low deposition density due to nonspherical particle generation in FHD process. Silica core particles deposited at various conditions such as flame temperature and substrate scanning were analyzed by SEM and TEM. As the flame temperature increased, the surface roughness of the core layer was decreased up to 3.6 nm after consolidation. Index difference and thickness of core of slab waveguide were 0.3%, 8$\mu\textrm{m}$ respectively. Measured optical loss at TE mode was <0.04 dB/cm at 1.3$\mu\textrm{m}$ and <0.06 dB/cm at 1.55$\mu\textrm{m}$.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09b
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• pp.1191-1192
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• 2006

Eventhough Fe-6.5 wt.% Si alloy shows excellent magnetic properties, magnetic components made of the alloy are not totally because of its extremely low ductility. In order to overcome this demerit of alloy, 6.7 wt.% Si alloy powders were produced by gas atomization and then post-processed to form magnetic cores. By doing so, the total core loss could be minimized by reducing both hysteresis and eddy current loss. From our experiments, we were able to achive a core loss of $390mW/cm^3$ at 0.1 T and 50 kHz through proper processes and a permeability $\mu_{eff}$ of 68 at low frequency.

• Journal of Environmental Science International
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• v.20 no.3
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• pp.385-394
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• 2011

Organotin compounds (OTs), namely butyltins compounds (BTs) and phenyltin compounds (PhTs), were measured in surface and core sediments collected in Jeju harbor. The horizontal and vertical distribution was examined and the relationship between the concentration of OTs and organic matter content and particle size distribution was also studied. BTs were detected in significant concentrations in sediments inside Jeju harbor. PhTs were detected in very low concentrations, compared to BTs. The main species in BTs and PhTs were dibutyltin (DBT) and monobutyltin (MBT), monophenyltin (MPhT), respectively. In the relationships between the concentrations of total BTs and organic carbon content, the significant correlations ($r^2$=0.4898 in surface sediments, $r^2$=0.53 in one core sediments) and no correlation in another core sediments obtained, which is estimated that the distribution of BTs in sediments were affected by several factors, such as their physicochemical properties including organic carbon content, and a tide, etc. In the relationships between the concentrations of total BTs and particle size (mud, sand, and gravel) in sediments, the concentrations of total BTs were higher in the sediments with higher mud content, indicating that higher BTs were distributed with increasing sediments of fine granules.

• Nuclear Engineering and Technology
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• v.54 no.6
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• pp.1935-1946
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• 2022

The investigations of the coated-particles of nuclear fuel samples are carried out in three stages: front-end, irradiation in the reactor core, and post-irradiation examination. The front-end stage is the initial analysis of the failures rates of produced samples before they are placed in the reactor core. The purpose of the verification is to prepare the particles for an experiment that will determine the degree of damage to the coated particles at each stage. Before starting experiments with the samples, they must be properly prepared. Polishing the samples in order to uncover the inner layers is an important, initial experimental step. The authors of this paper used a novel way to prepare samples for testing - by applying an ion polisher. Mechanical polishing used frequently for sample preparations generates additional mechanical damages in the studied fuel particle, thus directly affecting the experimental results. The polishing methods were compared for three different coated particles using diagnostic methods such as Raman spectroscopy, scanning electron microscopy, and confocal laser scanning microscopy. Based on the obtained results, it was concluded that the ion polishing method is better because the level of interference with the structures of the individual layers of the tested samples is much lower than with the mechanical method. The same technique is used for the fuel particles undergone ion implantation simulating radiation damage that can occur in the reactor core.

• Nuclear Engineering and Technology
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• v.56 no.1
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• pp.283-291
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• 2024

Sodium cooled Fast Reactors (SFR) are built with several engineered safety features and hence a severe accident such as a core melt accident is hypothetical with a probability of <10^-6/ry. However, in case of such accidents, the mixture of the molten fuel and structural materials interacts with sodium. This phenomenon is known as Molten Fuel Coolant Interaction (MFCI) and results in fragmentation of the melt due to various instabilities. The fragmented particles settle as a debris bed on the core catcher at the bottom of the reactor vessel, and continue to generate decay heat. Characteristics of the debris particles play a vital role in heat transfer from the bed and need thorough investigation. The size, shape, and physical state of the debris depend on the associated fragmentation mechanism, superheating of the melt, and sodium temperature. Experiments have been conducted by releasing simulated corium, a molten mixture of alumina and iron generated by the aluminothermy process at ~2400 ℃ into liquid sodium, to study the fragmentation phenomena. After the experiment, the fragmented debris was retrieved and the particle size distribution was determined by sieve analysis. The debris was subjected to microscopic investigation for obtaining morphological characteristics. Based on the characteristics of debris, an attempt has been made to assess of fragmentation mechanism of simulated corium in sodium.

• Proceedings of the Korean Magnestics Society Conference
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• 2013.12a
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• pp.57-58
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• 2013

• Textile Coloration and Finishing
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• v.15 no.6
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• pp.8-17
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• 2003

In order to investigate the possibility of PVA particle as toner, PVA/PVAc particle was manufactured. Fine spherical PVAc particle with emulsifier SDS(sodium Dodecyl Sulfate) and initiator V-50(2,2'- azo bis(2-amidinopropane) dihydrochloride) was manufactured by emulsion polymerization. And then, the PVAc was carried with surface saponification. PVA/PVAc skin core structured particle was obtained under optimum saponification condition. PVA skin side in manufactured PVA/PVAc particles was dyed with 1:2 metal complex type C. I. Acid Yellow 235 and then the dyed PVA particles were observed with a optical microscope. Under given polymerization condition such as SDS concentration, $1.62\times{10}^{-2} \;mol/lH_2O$, V-50 concetration, $3.7\times{10}^{-3}\;mol/lH_2O$ and temperature $50^\circ{C}$ , the high molecular weight of PVAc with Pn 13,900 and PVA with Pn 3,400 was produced. The particle distribution of obtained PVAc microspheres was appeared highly at 60 and $100\mu{m}$, respectively.