• The Journal of the Convergence on Culture Technology
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• v.5 no.3
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• pp.229-239
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• 2019

Rapid economic development has changed the dietary habits and patterns. Especially, western style diet has increased the risk of type 2 diabetes (T2DM) in Korea. To provide more specific and appropriate diet guideline for the prevention and for the treatment of T2DM, the investigation on the characteristics of diebetic patients related to the diet needs to be done. In this study, we therefore analyzed eating behaviors, dietary attitudes, and intake of food and nutrients of normal subjects (control, n=26) and diabetic patients (case, n=18) diagnosed T2DM within one year in Daegu Gyeongbuk area. Body mass index of the patients were significantly higher than the control (p<0.05). Overeating, high fried food and low whole grain intake were revealed as risk factors for T2DM. From the food frequency questionnaire analysis, salty foods such as fermented soybean paste (Doenjang) and watery Kimch intake were associated with T2DM. Intake of vegetable lipid, ${\beta}$-carotene, calcium, copper, and vitamin K were also shown to be associated with T2DM. Taken together, these findings suggest that maintaining ideal body weight and intake the foods with low salt, fat, and refined grain in appropriate amount may help to prevent and to manage T2DM.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.6 no.2
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• pp.161-166
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• 2003

Purpose: The purpose of this study was to evaluate the efficiency of treatment of living-related liver transplantation (LRLT) with the parental heterozygote carrier graft in children with Wilson disease. Methods: We retrospectively evaluated 7 children with Wilson disease who had received liver transplantation from 1994 to 2002 at Asan Medical Center. All the donors were parental. Liver functions, Kayser-Fleischer ring, and other factors regarding to copper metabolism were analyzed. Results: Of the 7 children, 5 had fulminant hepatitis and 2 had decompensated liver cirrhosis irresponsive to medical therapy. All donors being parental, all grafts came to be heterozygote carrier grafts. Survival rate was 100% in those 7 children, 87% in all children with liver transplantation in the same period, and 84% in children with non-metabolic liver disease. After liver transplantation, all 7 children could stop low copper diet and penicillamine therapy and their AST, total bilirubin and prothrombin time were recovered to normal. After liver transplantation, ceruloplasmin and serum copper levels were also recovered to normal. A marked reduction in 24 hr-urinary copper excretion was observed in all recipients after transplantation. During follow-up, Kayser-Fleischer rings resolved completely after LRLT in 5 children and partially in 1 child. Conclusion: We concluded that living-related liver tranplantation in children with Wilson disease with parental heterozygote carrier graft is an effective treatment modality.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.1
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• pp.132-138
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• 2020

Objective: To investigate the effects of low-dose trace mineral proteinates on reproductive performance, mineral status, milk immunoglobulin contents and fecal mineral excretion of sows. Methods: Eighty crossbred sows (Landrace×Large White) were randomly allocated to two groups in a 135-day trail, from breeding through 21 d postpartum. The two treatments were inorganic trace minerals (ITM): a basal diet+inorganic iron (Fe), copper (Cu), manganese (Mn), and zinc (Zn) at 90, 15, 25 and 90 mg/kg, respectively and organic trace minerals (OTM): a basal diet+proteinates of Fe, Cu, Mn, and Zn at 72, 12, 20, and 72 mg/kg, respectively. Results: Compared with ITM, OTM significantly increased (p<0.05) the number of piglets with birthweight >1 kg, the litter weaning weight, and milk Fe, Cu contents. No significant differences (p>0.05) were observed on sow hair mineral contents or immunoglobulin M (IgM), IgG, and IgA contents in colostrum and milk. In comparsion to ITM, OTM decreased fecal Fe, Cu, Mn, and Zn contents of gestating sows (p<0.01) and Fe, Mn, and Zn in lactating sows (p<0.01). Conclusion: These results indicate that low-dose mineral proteinates can increase the number of piglets with birthweight >1 kg, the litter weaning weight and certain milk mineral concentrations while reducing fecal mineral excretion.

• Journal of the Korean Society of Food Science and Nutrition
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• v.22 no.6
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• pp.716-723
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• 1993

This study was carried out to estimate intake level of Pb, Fe, Cu in rural area of Korea(12 males and 18 females). Analyses for the nutritional status of the record, duplicated diet collections, 24-hour urine collections, and venous blood sampling before measuring of blood pressure. The mean age and blood pressure of the subjects were 45.8$\pm$11.1years and 117.5$\pm$22.2/80.8$\pm$15.6mmHe in males, and 41.9$\pm$11.0years, 110.0$\pm$ 11.9/73.9$\pm$8.5mmHg in females, respectively. In respect to both males and females, mean BMI were 22.0$\pm$2.3, 23.1$\pm$3.0, mean Rohrer index were 131.8$\pm$14.8, 142.4$\pm$20.2 and mean skinfold thickness were 12.4$\pm$5.9mm, 25.3$\pm$7.4mm, respectively. The daily mean intakes of Pb, Fe, and Cu estimated for 3 days were 277.2$\pm$111.2$\mu\textrm{g}$/day, 12.7$\mu\textrm{g}$ 7.6mg/day, and 3.0$\pm$1.4mg/day in males and 192.0$\pm$72.4$\mu\textrm{g}$/day, 13.3$\pm$5.8mg/day, and 3.7 $\pm$1.7mg/day in females, respectively. The mean concentrations of serum Pb, Fe, Cu were 11.0$\pm$2.0$\mu\textrm{g}$/dl, 131.1$\pm$42.6$\mu\textrm{g}$/dl, 120.3$\pm$25.7$\mu\textrm{g}$/dl in males and 9.0$\pm$1.2$\mu\textrm{g}$/dl, 112.2$\pm$ 35.9$\mu\textrm{g}$/dl, 117.3$\pm$17.9$\mu\textrm{g}$/dl in females, respectively. The mean levels of Hb and Hct were 15.1$\pm$1.1g/dl, 45.2$\pm$3.3% in males and 13.1$\pm$0.8g/dl, 39.8$\pm$2.6% in females, respectively. The 24-hour urinary excretions of Pb, Fe, Cu were 35.5$\pm$10.0$\mu\textrm{g}$/day, 0.16$\pm$0.12mg/day, 60.12$\pm$0.02$\mu\textrm{g}$/day in males, and 25.3$\pm$11.0$\mu\textrm{g}$/day, 0.24$\pm$0.20mg/day, 70.07$\pm$0.03$\mu\textrm{g}$/day in females, respectively. In conclusion, the Pb intake in self selected diet of this subjects was not in the level that antagonized to Fe and Cu metabolism seriously.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.10
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• pp.1395-1403
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• 2012

The objective of the study was to quantify annual and seasonal differences in the chemical composition, in vitro gas production, in situ degradability and ruminal fermentation of grazing steers… diets. Diet samples were collected with four esophageal cannulated steers ($350{\pm}3$ kg BW); and four ruminally cannulated heifers ($342{\pm}1.5$ kg BW) were used to study the dry matter degradation and fermentation in rumen. Data were analyzed with repeated measurements split plot design. The crude protein, in vitro dry matter digestibility and metabolizable energy were higher during the first year of trial and in the summer (p<0.01). The values of calcium, phosphorus, magnesium, zinc and copper were higher in summer (p<0.05). The gas produced by the soluble and insoluble fractions, as well as the constant rate of gas production were greater in summer and fall (p<0.01). The ammonia nitrogen ($NH_3N$) and total volatile fatty acids concentrations in rumen, the soluble and degradable fractions, the constant rate of degradation and the effective degradability of DM and NDF were affected by year (p<0.05) and season (p<0.01). Our study provides new and useful knowledge for the formulation of protein, energetic and mineral supplements that grazing cattle need to improve their productive and reproductive performance.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.11
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• pp.1614-1621
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• 2013

The aim of this study was to investigate the effects of graded levels of montmorillonite, a constituent of clay, on performance, hematological parameters and bone mineralization in weaned pigs. One hundred and twenty, 35-d-old crossbred pigs (Duroc${\times}$Large White${\times}$Landrace, $10.50{\pm}1.20$ kg) were used in a 28-d experiment and fed either an unsupplemented corn-soybean meal basal diet or similar diets supplemented with 0.5, 1.0, 2.5 or 5.0% montmorillonite added at the expense of wheat bran. Each treatment was replicated six times with four pigs (two barrows and two gilts) per replicate. Feed intake declined (linear and quadratic effect, p<0.01) with increasing level of montmorillonite while feed conversion was improved (linear and quadratic effect, p<0.01). Daily gain was unaffected by dietary treatment. Plasma myeloperoxidase declined linearly (p = 0.03) with increasing dietary level of montmorillonite. Plasma malondialdehyde and nitric oxide levels were quadratically affected (p<0.01) by montmorillonite with increases observed for pigs fed the 0.5 and 1.0% levels which then declined for pigs fed the 2.5 and 5.0% treatments. In bone, the content of potassium, sodium, copper, iron, manganese and magnesium were decreased (linear and quadratic effect, p<0.01) in response to an increase of dietary montmorillonite. These results suggest that dietary inclusion of montmorillonite at levels as high as 5.0% does not result in overt toxicity but could induce potential oxidative damage and reduce bone mineralization in pigs.

• Journal of The Korean Society of Grassland and Forage Science
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• v.36 no.3
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• pp.191-198
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• 2016

This study evaluated the effects of TMC (trace mineral-fortified microbial culture) supplementation on growth performance, carcass characteristics, and meat quality parameters of Hanwoo steers during the last 4 months of finishing period. The TMC was a combination of 0.4% trace minerals, 20.0% Na-bentonite, and 79.6% feedstuffs, which was inoculated with a mixed microbial culture (Enterobacter ludwigii, Bacillus cereus, B. subtilis, Lactobacillus plantarum, and Saccharomyces cerevisiae). Twenty-four steers were blocked by initial BW ($634{\pm}16kg$) and randomly allocated to one of two treatments (control vs. 3.3% TMC). The effect of TMC supplementation on the growth performance was not significant. There was no incidence of urolithiasis in TMC-fed steers. However 3 out 12 steers (25%) fed the control diet were observed to have urinary calculi. The carcass yield and meat quality parameters were not affected by TMC supplementation, however marbling score was increased in TMC-fed steers (P = 0.08). There was no effect of TMC treatment on the chemical composition of longissimus dorsi muscle (LM). The TMC supplementation increased concentrations of manganese (P < 0.01), cobalt (P = 0.02), iron, and copper (P = 0.06) in LM. In conclusion, TMC treatment did not negatively affect growth performance and meat quality parameters, and positively affected the trace minerals profile of LM.

• Journal of Environmental Health Sciences
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• v.15 no.1
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• pp.33-49
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• 1989

Pollution in the rivers has received considerable attention in recent years, particullary with reference to the effect due to increasing concentration of heavy metals. The metals are toxic to the ecosystem as a whole and to man in particular, since he is at the end of a variety of food chains by virture of his varigated diet. In addition, numerous laboratory tests have established that certain metals, such as Cd, pose a threat to a wide variety of aquatic organisms at concentrations as low as a few $\mu$g/1. Before the biological effects of heavy metals in impacted ecosystems can be completely assessed, however it is necessary to provide data on the concentration of heavy metals in such systems. This study was performed to investigate the concentration level of heavy metals in water, fish and sediments from upstream ($S_1-S_4$) to downstream ($S_5-S_9$) of the Mankyung river. Samples of water, fish, and sediments were collected along the tributaries of the Mankyung from September to October in 1987 and analyzed for lead, cadmium, copper, and zinc by atomic absorption spectrophotometer. From the data presented in this study, we can infer that the concentrations of the heavy metals investigated both in water and sediments are similar to those found in literature for unpolluted regions. The results obtained from the analysis of the edible tissue of the C. auratus show low concentration levels of the four heavy metals investigated. We conclude that the area is still relatively unpolluted and recommended continuing the monitoring of heavy metal concentrations to improve our understanding of their cycle in the river environment.

• Nuclear Engineering and Technology
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• v.8 no.4
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• pp.195-201
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• 1976

The present levels for the contents of mercury, arsenic, bromine, copper, manganese and potassium in various groups of foodstuffs are evaluated and compared with data given previously by others. On the basis of the data for the levels, the average daily intakes have teen estimated to be 2.0$\times$10$^1$$\mu\textrm{g}$ for Hg, 3.2$\times$10$^2$$\mu\textrm{g}$ for As, 2.3$\times$10$^3$$\mu\textrm{g}$ for Br, 2.5$\times$10$^3$$\mu\textrm{g}$ for Cu, 6.8$\times$10$^3$$\mu\textrm{g}$ for Mn and 2.1$\times$10$^{6}$ $\mu\textrm{g}$ for K. For this purpose, the data reported as a result of the 1974 National Nutrition Survey have been used.

• Korean Journal of Poultry Science
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• v.36 no.2
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• pp.103-110
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• 2009

This experiment was conducted using 350 Lohmann Brown layers (67 weeks of age) to evaluate the dietary effect of organic or inorganic Se and Cu on their contents in chicken eggs. The layers were divided into seven groups and fed a commercial diet or one of the six experimental diets containing different levels of Se and Cu (T1, 0.3ppm organic Se; T2, 1.0ppm organic Se; T3, 1.0ppm inorganic Se; T4, 125ppm organic Cu; T5, 250ppm organic Cu; and T6, 250ppm inorganic Cu) for 5 weeks. No significant differences were observed in egg production and its qualities among groups. The contents of blood cholesterol in the birds fed various levels of Se and Cu were not significantly different as compared to control. Se contents in eggs were linearly increased as dietary Se levels increased for both sources, but Se contents from the groups fed organic Se were slightly higher than those fed inorganic Se. Sensory characteristics of eggs were not influenced by dietary treatments. In conclusion, Se contents in eggs were linearly increased as dietary levels of organic or inorganic Se increased, but eggs in layers fed the diet containing organic Se did not show higher Se contents than those in birds fed dietary inorganic Se.