• Tuberculosis and Respiratory Diseases
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• 제84권2호
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• pp.134-139
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• 2021

Background: Intrapleural urokinase is one of the most widely used fibrinolytic agents in the treatment of complicated parapneumonic effusion (CPPE). However, little research has been performed on the optimal urokinase dosage. The aim of this study was to evaluate the treatment efficacy of half dose urokinase compared with conventional dose urokinase. Methods: We retrospectively enrolled 92 patients with CPPE or empyema who underwent intrapleural urokinase treatment at two tertiary hospitals. Patients received antibiotics, chest tube drainage, and other treatments as part of routine care. The primary outcome was the treatment success rate in the half dose urokinase group (50,000 IU daily for maximal 6 days) and the conventional dose urokinase group (100,000 IU daily). Treatment success was defined as clinical and radiological improvements without surgical treatment or re-admission within one month. Results: Forty-four patients received half dose urokinase, whereas 48 patients were treated with conventional dose urokinase. Both groups were relatively well matched at baseline, excluding higher serum white blood cell count and higher empyema prevalence in the half dose urokinase group. The treatment success rate was not different between the two groups (p=0.048). There were no differences in the rate of in-hospital death and surgical treatment, hospitalization duration, and indwelling catheter duration. In the multivariate analysis, urokinase dose was not a predictor of treatment success. Conclusion: Half dose intrapleural urokinase is equally effective conventional dose urokinase in treating patients with CPPE or empyema.

• Restorative Dentistry and Endodontics
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• 제42권2호
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• pp.125-133
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• 2017

Objectives: This study compared the effect of hexamethyldisiloxane (HMDSO) and ammonia ($NH_3$) plasmas on the bond strength of resin cement to fiber posts with conventional treatments. Materials and Methods: Sixty-five fiber posts were divided into 5 groups: Control (no surface treatment); $H_2O_2$ (24% hydrogen peroxide for 1 min); Blasting (blasting with aluminum oxide for 30 sec); $NH_3$ ($NH_3$ plasma treatment for 3 min); HMDSO (HMDSO plasma treatment for 15 min). After the treatments, the Ambar adhesive (FGM Dental Products) was applied to the post surface (n = 10). The fiber post was inserted into a silicon matrix that was filled with the conventional resin cement Allcem Core (FGM). Afterwards, the post/cement specimens were cut into discs and subjected to a push-out bond strength (POBS) test. Additionally, 3 posts in each group were evaluated using scanning electron microscopy. The POBS data were analyzed by one-way analysis of variance and the Tukey's honest significant difference post hoc test (${\alpha}=0.05$). Results: The Blasting and $NH_3$ groups showed the highest POBS values. The HMDSO group showed intermediate POBS values, whereas the Control and $H_2O_2$ groups showed the lowest POBS values. Conclusion: Blasting and $NH_3$ plasma treatments were associated with stronger bonding of the conventional resin cement Allcem to fiber posts, in a procedure in which the Ambar adhesive was used.

• Tuberculosis and Respiratory Diseases
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• 제81권2호
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• pp.148-155
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• 2018

Background: Although targeted therapy and immuno-oncology have shifted the treatment paradigm for lung cancer, platinum-based combination is still the standard of care for advanced non-small cell lung cancer (NSCLC). Pemetrexed continuation maintenance therapy has been approved and increasingly used for patients with nonsquamous NSCLC. However, the efficacy of this strategy has not been proven in patients without driving mutations. The objective of this study was to compare the clinical benefit of pemetrexed continuation maintenance to conventional platinum-based doublet in epidermal growth factor receptor (EGFR)-negative lung adenocarcinoma. Methods: A total of 114 patients with EGFR-negative lung adenocarcinoma who were treated with platinum doublet were retrospectively enrolled. We compared the survival rates between patients received pemetrexed maintenance after four-cycled pemetrexed/cisplatin and those received at least four-cycled platinum doublet without maintenance chemotherapy as a first-line treatment. Results: Forty-one patients received pemetrexed maintenance and 73 received conventional platinum doublet. Median progression-free survival (PFS), which was defined as the time from the day of response evaluation after four cycles of chemotherapy to disease progression or death, was significantly higher in the pemetrexed maintenance group compared to conventional group (5.8 months vs. 2.2 months, p<0.001). Median overall survival showed an increasing trend in the pemetrexed maintenance group (22.3 months vs. 16.1 months, p=0.098). Multivariate analyses showed that pemetrexed maintenance chemotherapy was associated with better PFS (hazard ratio, 0.73; 95% confidence interval, 0.15-0.87). Conclusion: Compared to conventional platinum-based chemotherapy, premetrexed continuation maintenance treatment is associated with better clinical outcome for the patients with EGFR wild-type lung adenocarcinoma.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제42권
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• pp.11.1-11.8
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• 2020

Background: The purpose of this study is to compare the skeletal stability of two-jaw surgery via surgery-first approach with conventional two-jaw surgery in facial asymmetry patients by measuring the skeletal changes after surgery from a three-dimensional analysis. From January 2010 to January 2014, 40 patients with facial asymmetry who underwent two-jaw surgery in Pusan National University Hospital were included in this study. They were classified into experimental group (n = 20) who underwent two-jaw surgery via surgery-first approach and control group (n = 20) who underwent conventional two-jaw surgery. After selection of 24 landmarks and the construction of horizontal and sagittal, coronal reference planes, changes in 10 linear measurements and 2 angular measurements were compared between the surgery-first approach and conventional groups in the preoperative, immediate postoperative, and postoperative periods. The paired t test and Student t test were used for statistical analysis. The mean and standard deviation of the measurement were calculated for the experimental and control groups. Results: The statistical analysis showed that changes in skeletal measurements were similar between the surgery-first approach and conventional groups, according to each period. However, U1-SRP measurement showed statistically significant changes in surgery-first approach groups at postsurgical change (T1 to T2). Also, the mean treatment duration in the treatment group was 15.9 ± 5.48 months whereas that in the control group was 32.9 ± 14.05 months. Conclusion: In facial asymmetry patients, similar results were observed in the postoperative skeletal stability when 2-jaw surgery via surgery-first approach was compared with conventional 2-jaw surgery. However, significant lateral deviation of upper incisor midline was observed. In addition, a shorter average treatment duration was observed. To stabilize the unstable occlusion after surgery, increased wearing of the stent and proactive rubber guidance will be needed.

• 한국환경과학회지
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• 제19권11호
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• pp.1315-1322
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• 2010

A membrane bioreactor (MBR) was designed using polyvinylidene fluoride(PVDF)-type hollow fiber membrane modules with a treatment capacity of 10 ton/day. A pilot plant was installed in a sewage treatment plant and was operated with an intermittent aeration method which avoids any concentration gradient of suspended solids (SS) in the MBR. For continuous operation, the pilot plant was first tested with influent (mixed liquor suspended solid:MLSS of 1000-2000 mg/L) of aeration tanks in the sewage treatment plant. The MBR was pre-treated with washing water, 10% ethanol solution, 5% NaOCl solution and finally washing water, one after another. To demonstrate the effect of the MBR on sewage treatment, compared with conventional activated sludge processes, we investigated the relationships among permeate amount (LMH), change in operation conditions, influent MLSS level and sludge production. It was found that the optimum aeration rate and suction pressure were $0.3\;m^3$/min and 30~31 cmHg, respectively. Under stable conditions in aeration, suction pressure, influent flow rate and drainage, the SS removal efficiency was more than 99.99% even when the MLSS loading rate changes. Compared with conventional activated sludge processes, the MBR was more effective in cost reduction by 27% based on permeate amount and by 51.5% on sludge production.

• 열처리공학회지
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• 제36권2호
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• pp.86-95
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• 2023

This paper explained the equipment and process development to secure the source technology of controlled nitrification technology. The nitriding potential in the furnace was controlled only by adjusting the flow rate of ammonia gas introduced into the furnace. In addition, a control system was introduced to automate the nitriding process. The equipment's hardware was designed to enable controlled nitriding based on the conventional gas nitriding furnace, and an automation device was attached. As a result of measuring the temperature and quality uniformity for the equipment, the temperature and compound uniformity were ±1.2℃ and 14.3 ± 0.2 ㎛, respectively. And, it was confirmed that nitriding potential was controlled within the tolerance range of AMS2759-10B standard. In addition to parts for controlled nitriding, it was applied to products produced in existing conventional nitriding furnaces, and as a result, gas consumption was reduced by up to 80%.

• The Journal of Advanced Prosthodontics
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• 제3권4호
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• pp.236-239
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• 2011

Maxillary labial and buccal frena are considered as normal anatomic structures in the oral cavity. However, they may exist intraorally as a thick broad fibrous attachment and/or become located near the crest of the residual ridge, thus interfering with proper denture border extension resulting in inferior denture stability, retention and overall patient satisfaction. This case report highlights the importance of clinical examination and treatment planning which may mandate preprosthetic surgery prior to fabrication of a new conventional complete denture. Adequate patient satisfaction with conventional complete dentures can be significantly increased after frenectomy.

• 한국환경과학회지
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• 제15권9호
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• pp.829-834
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• 2006

This research aims to investigate the behavior of organic matter that causes bacterial re-growth and the formation of disinfectant by-products such as THM in water treatment, and to optimize conditions for a more efficient and conventional water facility. THM removed 51 % and 12 % through coagulation/sedimentation and filtration using a selected conventional system. In this experiment, the removal ratio of DOC was highest at 68 % when the Gt value was 42,000 and lowest at 41 % when the Gt value was 30,000. 77-84 % of total DOC was removed during coagulation/sedimentation, and 15-23 % was removed during filtration. When Gt values were between 30,000 and 66,000, over 50 % of high molecular matter above 10 K during coagulation/sedimentation was removed. Turbidity removed 98 % when the G1 value was 66,000. As the Gt value increased, the turbidity removal ratio increased. Turbidity removed over 20 % during the filtration process.

• 환경위생공학
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• 제16권1호
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• pp.40-46
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• 2001

Conventional membrane systems was difficult to treatment for pulp and paper mills waste warter. Technological advances in membrane filtration systems have created opportunity for pulp and paper mills to treat effluent streams in order to meet stricter environmental constraints. "Vibratory Shear Enhanced Processing(VSEP)" developed by new logic international makes if possible to filter effluent streams without the fouling problems exhibited by conventional membrane systems. Various kinds of waste water occurred to and paper mills experiment with "VSEP" set up conventional membrane. The results were as followes : Excepting ultra filter($0.1{\mu}\textrm{m}$ Teflon, C-100, G-50), Nano filter(NTR-7450, DS-5, PVD-1) and reverse osmosis(ACM-4) was treated with very excellent weight of treatment, electric conductivity, removal COD, TDS, turbidity.

• 자연과학논문집
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• 제11권1호
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• pp.113-117
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• 1999

사과 스타크림손품종에 질소시용량을 달리하였을 때 질소 다량 시용구가 표준 시용구보다 과실의 칼슘함량이 적었다. 칼슘용액의 수관살포로 과실 칼슘함량이 증가되었고 반점성 생리장해발생이 감소되었는데 특히 질소표준구에서 칼슘함량 증가가 뚜렷하였다. 사양토에 재식된 후지품종에 대한 관수는 과실의 비대와 잎과 과실의 칼슘함량을 증가시키는 효과가 있었다.