Savin, Stanislav;Kravchyk, Yurii;Dzhereliuk, Yuliia;Dyagileva, Olena;Naboka, Ruslan
International Journal of Computer Science & Network Security
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v.21
no.12
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pp.45-52
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2021
The article proves the relevance of developing conceptual frameworks for managing the quality assurance of logistics activities in the context of socio-economic interaction of their participants. It is established that the fundamental difference of the logistic approach in management from traditional approaches is the allocation of a single management function of previously separated, disparate material flows, as well as economic, technological, information integration of chain links into a single system capable of effective management of these flows. It is substantiated that the functioning of the enterprise as a logistics system can be represented in the form of a triad of logistics components, namely: supply logistics, production logistics, sales logistics. Management of quality assurance processes of logistics activities in the context of socio-economic interaction of their participants is a functional component of the entire logistics system due to the quality of work and interaction of all participants in the implementation of certain activities. The quality of logistics activities will affect the level of economic potential, rationalization and optimization of all logistics flows. It is proved that the management of quality assurance processes of logistics activities in the context of socio-economic interaction of their participants involves the following main areas: the introduction of a quality system of logistics processes; development and implementation of the general strategy of quality improvement at the enterprise; internal integration; controlling. Management of quality assurance processes of logistics activities in the context of socio-economic interaction of its participants requires compliance with the following requirements: systematic and comprehensive management of all flow processes; coordination of criteria and indicators for assessing the effectiveness of the entire logistics system; dissemination of the use and application of information technology; ensuring partnerships and close interaction of all participants in sales networks.
Cowpea mild mottle virus (CPMMV) is a global plant virus that poses a threat to the production and quality of legume crops. Early and accurate diagnosis is essential for effective managing CPMMV outbreaks. With the advancement in isothermal recombinase polymerase amplification and lateral flow strips technologies, more rapid and sensitive methods have become available for detecting this pathogen. In this study, we have developed a reverse transcription recombinase polymerase amplification combined with lateral flow strips (RT-RPA-LFS) method for the detection of CPMMV, specifically targeting the CPMMV coat protein (CP) gene. The RT-RPA-LFS assay only requires 20 min at 40℃ and demonstrates high specificity. Its detection limit was 10 copies/µl, which is approximately up to 100 times more sensitive than RT-PCR on agarose gel electrophoresis. The developed RT-RPA-LFS method offers a rapid, convenient, and sensitive approach for field detection of CPMMV, which contribute to controlling the spread of the virus.
Since the previous studies on the effects of trade liberalization implicitly assume that trade liberalization affects economic performance only in any point in time, they inevitably are static. Static evaluations fail to account for cumulative dynamic effects of trade liberalization that affect continuously economic performance. This paper tries to fill this gap of the previous studies in this field, estimating cumulative effects of trade liberalization on economic performance by employing an dynamic version of empirical model. One of important empirical issue is controlling bias from endogeneity. To resolve this problem, this paper employes system GMM that uses lagged first-differences as instruments for level equations and lagged levels as instruments for first-differences equations. It improves upon cross-section estimators because it controls for the potential bias induced by the omission of industry-specific effects and the endogeneity of all regressors. This study investigates the effects of trade liberalization in Korean manufacturing for the period from 1988 to 2005 and finds that cumulative dynamic effects of trade liberalization are present and bigger than static effects.
Processed meat products play a vital role in our daily dietary intake due to their rich protein content and the inherent convenience they offer. However, they often contain synthetic additives and ingredients that may pose health risks when taken excessively. This review explores strategies to improve meat product quality, focusing on three key approaches: substituting synthetic additives, reducing the ingredients potentially harmful when overconsumed like salt and animal fat, and boosting nutritional value. To replace synthetic additives, natural sources like celery and beet powders, as well as atmospheric cold plasma treatment, have been considered. However, for phosphates, the use of organic alternatives is limited due to the low phosphate content in natural substances. Thus, dietary fiber has been used to replicate phosphate functions by enhancing water retention and emulsion stability in meat products. Reducing the excessive salt and animal fat has garnered attention. Plant polysaccharides interact with water, fat, and proteins, improving gel formation and water retention, and enabling the development of low-salt and low-fat products. Replacing saturated fats with vegetable oils is also an option, but it requires techniques like Pickering emulsion or encapsulation to maintain product quality. These strategies aim to reduce or replace synthetic additives and ingredients that can potentially harm health. Dietary fiber offers numerous health benefits, including gut health improvement, calorie reduction, and blood glucose and lipid level regulation. Natural plant extracts not only enhance oxidative stability but also reduce potential carcinogens as antioxidants. Controlling protein and lipid bioavailability is also considered, especially for specific consumer groups like infants, the elderly, and individuals engaged in physical training with dietary management. Future research should explore the full potential of dietary fiber, encompassing synthetic additive substitution, salt and animal fat reduction, and nutritional enhancement. Additionally, optimal sources and dosages of polysaccharides should be determined, considering their distinct properties in interactions with water, proteins, and fats. This holistic approach holds promise for improving meat product quality with minimal processing.
Dukwon Lee;Hansol, Lee;Jinwook Lee;Soung-Hun Roh;Nam-Chul Ha
Molecules and Cells
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v.46
no.9
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pp.538-544
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2023
The formation of uniform vitreous ice is a crucial step in the preparation of samples for cryogenic electron microscopy (cryo-EM). Despite the rapid technological progress in EM, controlling the thickness of vitreous ice on sample grids with reproducibility remains a major obstacle to obtaining high-quality data in cryo-EM imaging. The commonly employed classical blotting process faces the problem of excess water that cannot be absorbed by the filter paper, resulting in the formation of thick and heterogeneous ice. In this study, we propose a novel approach that combines the recently developed nanowire self-wicking technique with the classical blotting method to effectively control the thickness and homogeneity of vitrified ice. With simple procedures, we generated a copper oxide spike (COS) grid by inducing COSs on commercially available copper grids, which can effectively remove excess water during the blotting procedure without damaging the holey carbon membrane. The ice thickness could be controlled with good reproducibility compared to non-oxidized grids. Incorporated into other EM techniques, our new modification method is an effective option for obtaining high-quality data during cryo-EM imaging.
Journal of the Korean Crystal Growth and Crystal Technology
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v.33
no.6
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pp.276-281
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2023
With the high design freedom of the additive manufacturing process, there is a growing interest in multi-dimensional lattice structures among researchers, who are studying intricate structural modeling that is challenging to produce using conventional manufacturing processes. In the case of titanium alloy implants for human insertion, a multi-dimensional lattice structure is employed to ensure compatibility with bones, adjusting strength and elastic modulus to levels similar to those of bones. Therefore, securing a database on the mechanical properties based on lattice structure design variables and the development of related simulation techniques are believed to efficiently facilitate the customization of implants. In this study, lattice structures were additively manufactured using Ti-6Al-4V alloy, and the elastic modulus was measured based on design parameters. The results were compared with simulations, and an approach to finite element analysis for accurate prediction of the elastic modulus was proposed.
Controlling vibrations and noise in steel box girders is important for reducing noise pollution and avoiding discomfort to residents of dwellings along bridges. The fundamental approach to solving this problem involves first identifying the main path of transmission of the vibration energy and then cutting it off by using targeted measures. However, this requires an investigation of the characteristics of flow of vibration energy in the steel box girder, whereas most studies in the area have focused on analyzing its single-point frequency response and overall vibrations. To solve this problem, this study examines the transmission of vibrations through the segments of a steel box girder when it is subjected to harmonic loads through structural intensity analysis based on standard finite element software and a post-processing code created by the authors. We identified several frequencies that dominated the vibrations of the steel box girder as well as the factors that influenced their emergence. We also assessed the contributions of a variety of vibrational waves to power flow, and the results showed that bending waves were dominant in the top plate and in-plane waves in the vertical plate of the girder. Finally, we analyzed the effects of commonly used stiffened structures and steel-concrete composite structures on the flow of vibration energy in the girder, and verified their positive impacts on energy regionalization. In addition to providing an efficient tool for the relevant analyses, the work here informs research on optimizing steel box girders to reduce vibrations and noise in them.
Screening performance of the existing intake screens (drum and travelling screen) on mass impingement of marine animals, a euphausiid, Euphausia pacifica and a scyphozoan medusae, Aurelia aurita that have often clogged intake screens of the Uljin Nuclear Power Plant, was tested. The maximum tolerable densities of marine animals in the inflowing seawater upon the screen were estimated with two different approaches. First the maximum density of jellyfish was calculated from (1) passing amount of seawater per unit time through the screens and (2) the covered area of animals on the screens clogged. The maximum density of krill tolerable in the drum screen was cited from a simulated record of Uljin NPP, then those in the travelling screens were also calculated using the data of drum screen and ratio of seawater amount passing through the screens under the condition of 0.5m water column (W.C.) of the differential pressure (AP) produced by screens, an established permissible limit of ${\Delta}P$. Secondly, the screening performances were also tested by hydrodynamic measurements with various screen models in a circulating water channel equipped with a speed-controlling pump and a differential pressure gauge. From the first approach, the maximum tolerable densities of drum and travelling screen were calculated as 2.0 and $1.5ind/m^3$ for the Jellyfish and 900 and $680ind./m^3$ for the euphausiid, respectively. These densities estimated from the second approach were 2.1 and $0.8ind/m^3$ for the jellyfish and 1059 and $504ind/m^3$ for the euphausiid, respectively. These estimates were compared with the data from historic clogging events to evaluate the practical performance of these intake screens. The comparisons suggest a newly improved intake-screen of which performance should be at least seven times (approximately) better than the existing ones ior the krill and 3.2 times for the jellyfish, respectively, for preventing mass impingement, and for maintaining the condition of the differential pressure between the screens below 0.3 m W.C.
This empirical study, activity-based costing, a newly introduced approach that has proved to be an improvement over the conventional costing system in product or service costing, is applied at department of clinical pathology in K university hospital. The study subjects were 233 test procedures done in clinical laboratory of K university hospital. Activity analysis was done by interview, questionnaires, and time study, and the amount of resources consumed by each activity and their costs are then traced and applied to the laboratory tests. The main purpose of this study were to compare the test costs of activity-bases costing with those of conventional costing, and test fees of medical insurance, and to provide accurate cost informations for the decision makers of hospital. The major findings of this study were as belows. 1. The cost drivers for application of activity-based costing at clinical laboratory were cases of sample collection, case of specimen, cases of test, and volume-related allocation bases such as direct labor hours and total revenue of each test. 2. The profits of each clinical laboratory fields analyzed by conventional costing were different from the profits analyzed by activity-based costing, especially in the field of Urinalysis(approximately over estimated 750%). 3. The standard full costs by conventional costing were quite different from the costs computed by using activity-based costing, and the difference is most significant with the tests of long labor time. 4. From the comparison between costs computed by using activity-based costing and medical insurance fees, some test fees were significantly lower than the costs, especially in the non-automated fields. As described in this study, activity-based costing provides more accurate cost information than does conventional costing system. The former approach is especially important in the health care industry including hospitals in which planning and controlling the costs services provided are the key to maintaining a healthy financial status for the organization. Despite the contribution of activity-based costing the economic as well as technical feasibilities of implementing such a cost accounting system in an organization must be evaluated. In the development of activity-based costing systems, an activity analysis has to be conducted to identify activities that consume resources. This involves a detailed study of the organization's logistics and accounting information systems, and it is an expensive project in itself. Besides, it can be quite difficult and time consuming to identify and trace resource consumption to a specific activity. Thus the activity-based costing system should be implemented only when the decrease in cost of error far exceeds the increase in cost of measurement. By combining activity-based costing with standard costing, health care administrators can better plan and control the costs of health services provided while ensuring that the organization's bottom line is healthy.
This study analyzes the apparent fracture toughness of a thick-walled cylinder with a functionally graded material (FGM) coating at the inner surface of the cylinder. The cylinder is assumed to have a single radial edge crack emanating from its inner surface. The crack surfaces and the inner surface of the cylinder are subjected to an internal pressure. The incompatible eigenstrain developed in the cylinder due to nonuniform coefficient of thermal expansion as a result of cooling from sintering temperature is taken into account. Based on a method of evaluating stress intensity factor introduced in our previous study, an approach is developed to calculate apparent fracture toughness. The approach is demonstrated for a cylinder with a TiC/$Al_{2}O_{3}$ FGM coating and some numerical results of apparent fracture toughness are presented graphically. The effects of material distribution profile, cylinder wall thickness, application temperature, and coating thickness on the apparent fracture toughness are investigated in details. It is found that all of these factors play an important role in controlling the apparent fracture toughness of the cylinder.
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