• Title/Summary/Keyword: contrast flow

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Time Slot Assignment Algorithm with Graph Coloring (그래프 채색에 의한 타임 슬롯 할당 알고리즘)

  • Kwon, Bo-Seob
    • The Journal of the Korea Contents Association
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    • v.8 no.5
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    • pp.52-60
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    • 2008
  • A simple Time Division Multiplex(TDM) switching system which has been widely in satellite networks provides any size of bandwidth for a number of low bandwidth subscribers by allocating proper number of time slots in a frame. In this paper, we propose a new approach based on graph coloring model for efficient time slot assignment algorithm in contrast to network flow model in previous works. When the frame length of an initial matrix of time slot requests is 2's power, this matrix is divided into two matrices of time slot requests using binary divide and conquer method based on the graph coloring model. This process is continued until resulting matrices of time slot requests are of length one. While the most efficient algorithm proposed in the literature has time complexity of $O(N^{4.5})$, the time complexity of the proposed algorithm is $O(NLlog_2L)$, where N is the number of input/output links and L is the number of time slot alloted to each link in the frame.

Design and Analysis of Piezoelectric Micro-Pump Using Traveling-Wave (진행파를 이용한 압전 마이크로 펌프의 설계와 해석)

  • Na, Yeong Min;Lee, Hyun Seok;Park, Jong Kyu
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.38 no.5
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    • pp.567-573
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    • 2014
  • Since the development of microelectromechanical systems (MEMS) technology for the medical field, various micro-fluid transfer systems have been studied. This paper proposes a micro-piezoelectric pump that imitates a stomach's peristalsis by using two separate piezoelectric elements, in contrast to existing micro-pumps. This piezoelectric pump is operated by using the valve-less traveling wave of peristalsis movement. If the piezoelectric plates at the two separated plates are actuated at the input voltage, a traveling wave occurs between the two plates. Then, the fluid migrates by the pressure difference generated by the traveling wave. Finite element analysis was performed to understand the mechanics of the combined system with piezoelectric elements, elastic structures, and fluids. The effects of design variables such as the chamber height and number of ceramics on the flow rate of the fluid were examined.

Tacrolimus Differentially Regulates the Proliferation of Conventional and Regulatory CD4+ T Cells

  • Kogina, Kazue;Shoda, Hirofumi;Yamaguchi, Yumi;Tsuno, Nelson H;Takahashi, Koki;Fujio, Keishi;Yamamoto, Kazuhiko
    • Molecules and Cells
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    • v.28 no.2
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    • pp.125-130
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    • 2009
  • Tacrolimus is a widely used T cell targeted immunosuppressive drug, known as a calcineurin inhibitor. However, the exact pharmacological effects of tacrolimus on $CD4^+$ T cells have yet to be elucidated. This study investigated the effects of tacrolimus on $CD4^+$ T cell subsets. Mouse or human $CD4^+$ T cells were cultured with immobilized anti-CD3/CD28 antibodies in the presence of tacrolimus. The cell division of $CD4^+$ T cells was analyzed using a flow cytometer according to the expression of Foxp3. The gene expression patterns of tacrolimus-exposed T cells were examined by quantitative PCR. In the case of conventional $CD4^+$ T cells (Tconv cells), tacrolimus inhibited T cell receptor stimulation-induced cell division. In contrast, the cell division of regulatory $CD4^+$ T cells (Treg cells) was even promoted in the presence of tacrolimus, especially in humans. Tacrolimus did not promote conversion of Tconv to Treg cells in mice. Furthermore, tacrolimus modified the expression levels of Foxp3-regulated T cell receptor signal related-genes, PTPN22 and Itk, in human Treg cells. Immunosuppressive effect of tacrolimus may be attributed to the relatively enhanced proliferation of Treg cells in association with altered gene expression levels of TCR signaling molecules.

Measurements of Vibration and Pressure of an Oxidizer Pump for a 7-tonf Turbopump with a Modified Rear Floating Ring Seal (수정된 후방 플로팅 링 실을 적용한 7톤급 터보펌프 산화제 펌프의 진동 및 압력 측정)

  • Bae, JoonHwan;Kwak, Hyun-Duck;Choi, ChangHo;Choi, JongSoo
    • Tribology and Lubricants
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    • v.36 no.5
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    • pp.253-261
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    • 2020
  • In this paper, we present an experimental investigation of the frequency characteristics and a visual inspection of an oxidizer pump with a modified rear-floating ring seal for a 7-tonf turbopump. An oxidizer pump typically operates at high rotational speeds and under cryogenic conditions. Despite its low hydraulic efficiency, the floating ring seal is frequently employed as a leakage control solution for turbomachinery because it effectively reduces abrasion by friction. When the oxidizer pump starts up, the floating ring moves excursively but locks up stably against the pump casing when the contact pressure increases. The compressive force on the floating ring depends on the hydrodynamic forces induced by the flow through the floating ring. This force is controlled by the nose position of the floating ring. Based on a validation test for a 7-tonf turbopump with two types of floating rings, we concluded that the floating ring with a small diameter nose can move easily with a low contact pressure in the cooling path. This leads to instability of the pressure fluctuation around the floating ring. In contrast, a floating ring with a large diameter nose has a high contact pressure and attaches strongly to the casing, which causes wear and frictional oxidation between the contact surfaces of the impeller and the floating ring.

The analysis of 18F-FDG PET/CT Images According to the Time Flow (시간흐름에 따른 18F-FDG PET/CT의 영상 분석)

  • Lee, Hyo-Yeong
    • Journal of the Korean Society of Radiology
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    • v.6 no.1
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    • pp.47-51
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    • 2012
  • PET/CT is taken 1 hour after $^{18}F$-FDG(F-18-fluoro-2-deoxy-D-glucose) injection. However, these would be often delayed for more than 2 or 3 hours due to equipment fault or unexpected situation. In the study, SUV(standardized uptake value) were measured from got image over time according to the parts of the body. As a result, there were great and small decrease in liver(middle of the right hepatic lobe), fat(Lt pelvis), lung (Rt upper lobe), aorta(ascending aorta level) of the body in delayed image, and ${\Delta}$SUVmax was increase of 37% in bone only(L5 vertebral body) of the body. ${\Delta}$SUVmax was increase of 37.6% in lesion, and the contrast degree was greater because of uptake increase in lesion and uptake decrease in the normal body.

Radionuclide Peritoneal Scintigraphy in Patients with Ascites and Pleural Effusion (방사성핵종 복막촬영술을 이용한 복수에 동반된 수흉의 감별 진단)

  • Lee, Jae-Tae;Lee, Kyu-Bo;Whang, Kee-Suk;Kim, Gwang-Weon;Chung, Byung-Cheon;Cho, Dong-Kyu;Chung, Joon-Mo
    • The Korean Journal of Nuclear Medicine
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    • v.24 no.2
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    • pp.279-285
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    • 1990
  • Simultaneous presence of ascites and pleural effusion has been documented in patients with cirrhosis of the liver, renal disease, Meigs' syndrome and in patients undergoing peritoneal dialysis. Mechanisms proposed in the formation of pleural effusion in most of the above diseases are lymphatic drainage and diaphragmatic defect. But sometimes, hepatic hydrothoraxes in the absence of clinical ascites and pleural effusion secondary to pulmonary or cardiac disease are noted. It is not always possible to differentiate between pleural effusion caused by transdiaphragmatic migration of ascites and by other causes based soly on biochemical analysis. Authors performed radionuclide scintigraphy after intraperitoneal administration of $^{99m}Tc-labeled$ colloid in 23 patients with both ascites and pleural effusion in order to discriminate causative mechanisms responsible for pleural effusion. Scintigraphy demonstrated the transdiaphragmatic flow of fluid from the peritoneum to pleural cavities in 13 patients correctly. In contrast, in 5 patients with pleural effusion secondary to pulmonary, pleural and cardiac diseases, radiotracers fail to traverse the diaphragm and localize in the pleural space. Ascites draining to mediastinal lymph nodes and blocked passage of lymphatic drainage were also clarified, additionaly. Conclusively, radionuclide peritoneal scintigraphy is an accurate, rapid and easy diagnostic tool in patients with both ascites and pleural effusion. It enables the causes of pleural effusion to be elucidated, as well as providing valuable information required when determining the appropriate therapy.

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Physical Layer Diversity and its Effects on the Performance of WLANs (물리 계층의 다양성과 무선 랜의 성능에 미치는 영향)

  • Choi, Sunwoong;Park, Kihong;Kim, Chong-Kwon
    • Journal of KIISE:Information Networking
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    • v.32 no.6
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    • pp.723-731
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    • 2005
  • Wide spread deployment of infrastructure WLANs has made Wi Fi an integral part of today's Internet access technology. Despite its crucial role in affecting end to end performance, past research has focused on MAC protocol enhancement, analysis and simulation based performance evaluation without sufficient consideration for modeling inaccuracies stemming from inter layer dependencies, including physical layer diversity, that significantly impact performance. We take a fresh look at IEEE 802.11 WLANs, and using experiment, simulation, and analysis demonstrate its surprisingly agile performance traits. Contention based MAC throughput degrades gracefully under congested conditions, enabled by physical layer channel diversity that reduces the effective level of MAC contention. In contrast, fairness and jitter significantly degrade at a critical offered load. This duality obviates the need for link layer flow control for throughput improvement but necessitates traffic control for fairness and QoS. We use experimentation and simulation in a complementary fashion, pointing out performance characteristics where they agree and differ.

The Design Development of Man's Royal Costume in TV Historical Drama (TV 사극 <이산>의 현대적 감각의 남자 궁중의상디자인 개발)

  • Lee, Keum-Hee;Lee, Hye-Lan
    • The Research Journal of the Costume Culture
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    • v.17 no.6
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    • pp.1112-1128
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    • 2009
  • The purpose of this study was to develop royal costume design with contemporary taste depending on the character of hero, Lee San, and time flow of TV historical drama and research design discrimination and creative expression. As study methods, the literature study using books and theses concerning costume, fine art, culture and history were used for theoretical background and the empirical study method manufacturing actual costume on the basis of literature and relic were used for dress manufacture. The design concept of costume was modern & chic & clean. The costume was designed through straight silhouette, clean & bright colors excluding prime colors, style transformed to permanent straight pleats on the basis of chulik, 100% silk material focusing on high quality and pattern & decoration of the age of Three Kingdoms. As results, the designs of princess' official rob, day dress and chulik, and emperor's official robe, chulik, military dress and chun-dam-bok were developed. The design discrimination depending on social status change. In the period of princess, black, white, silver and blue were used but in the period of emperor, red, gold and black were used. It was expressed through dragon pattern and extended length used in cloth. The design discrimination depending on character change was visualized through color. Although it is not consistent with historical investigation, contemporary fashion design elements were added to royal costume through color contrast of black & white, permanent straight pleats, velcore, wristlet, extended length and layered-look.

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Aerodynamic admittances of bridge deck sections: Issues and wind field dependence

  • Zhang, Zhitian;Zhang, Weifeng;Ge, Yaojun
    • Wind and Structures
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    • v.25 no.3
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    • pp.283-299
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    • 2017
  • Two types of aerodynamic admittance function (AAF) that have been adopted in bridge aerodynamics are addressed. The first type is based on a group of supposed relations between flutter derivatives and AAFs. In so doing, the aero-elastic properties of a section could be used to determine AAFs. It is found that the supposed relations hold only for cases when the gust frequencies are within a very low range. Predominant frequencies of long-span bridges are, however, far away from this range. In this sense, the AAFs determined this way are of little practical significance. Another type of AAFs is based on the relation between the Theodorsen circulation function and the Sears function, which holds for thin airfoil theories. It is found, however, that an obvious illogicality exists in this methodology either. In this article, a viewpoint is put forward that AAFs of bluff bridge deck sections are inherently dependent on oncoming turbulent properties. This kind of dependence is investigated with a thin plate and a double-girder bluff section via computational fluid dynamics method. Two types of wind fluctuations are used for identification of AAFs. One is turbulent wind flow while the other is harmonic. The numerical results indicate that AAFs of the thin plate agree well with the Sears AAF, and show no obvious dependence on the oncoming wind fields. In contrast, for the case of bluff double-girder section, AAFs identified from the turbulent and harmonic flows of different amplitudes differ among each other, exhibiting obvious dependence on the oncoming wind field properties.

THE ROLE OF MAPK AND PKC-${\delta}$ IN PHOSPHATIDIC ACID-MEDIATED INTERCELLULAR ADHESION MOLECULE-1 EXPRESSION (Phosphatidic acid에 의한 intercellular adhesion molecule-1 발현 조절에 관여한 MAPK와 PKC-${\delta}$의 역할)

  • Cho, Woo-Sung;Yoon, Hong-Sik;Chin, Byung-Rho;Baek, Suk-Hwan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.33 no.5
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    • pp.445-454
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    • 2007
  • Background: Phosphatidic acid(PA), an important second messenger, is involved in inflammation. Notably, cell-cell interactions via adhesion molecules playa central role in inflammation. This thesis show that PA induces expression of intercellular adhesion molecule-1(ICAM-1) on macrophages and describe the signaling pathways. Materials and methods: Macrophages were cultured in the presence of 10% FBS and assayed cell to cell adhesion using HUVEC. For the gene and protein analysis, RT-PCR, Western blot and flow cytometry were performed. In addition, overexpressed cell lines for dominant negative PKC-${\delta}$ mutant established and tested their effect on the promoter activity and expression of ICAM-1 protein by PA. Results: PA-activated macrophages significantly increased adhering to human umbilical vein endothelial cell and this adhesion was mediated by ICAM-1. Pretreatment with rottlerin(PKC-${\delta}$ inhibitor) or expression of a dominant negative PKC-${\delta}$ mutant, but not Go6976(classical PKC-${\alpha}$ inhibitor) and myristoylated PKC-${\xi}$ inhibitor, attenuated PA-induced ICAM-1 expression. The p38 mitogen-activated protein kinase(MAPK) inhibitor blocked PA-induced ICAM-1 expression in contrast, ERK upstream inhibitor didn't block ICAM-1. Conclusion: These data suggest that PA-induced ICAM-1 expression and cell-cell adhesion in macrophages requires PKC-${\delta}$ activation and that PKC-${\delta}$ activation is triggers to sequential activation of p38 MAPK.