• The Mathematical Education
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• v.58 no.4
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• pp.483-505
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• 2019

Across the world, there is a movement to incorporate computational thinking(CT) into school curricula, and math is at the heart of this movement. This paper reviewed the meanings of CT based on the point of view of Jeanette Wing, and the trend of domestic and international studies that incorporated CT into the field of mathematics education was analyzed to provide implications for mathematics education and future research. Results indicated that the meaning of CT, defined by mainly computer educators, varied in their operationalization of CT. Although CT and mathematical thinking generally have common points that are oriented toward problem solving, there were differences in the way of abstraction that is central to the two thinking processes. The experimental studies on CT in the field of mathematics education focused mainly on the development of students' cognitive capacities and affective domains through programming(coding). Furthermore, the previous studies were mainly conducted on students in school, and the studies conducted in the context of higher education, including pre-service and in-service teachers, were insufficient. Implications for mathematics teacher educators and teacher education as well as the relationship between CT and mathematical thinking are discussed.

• Journal of Advanced Navigation Technology
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• v.17 no.1
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• pp.69-79
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• 2013

In this paper, DCT(Discrete Cosine Transform) and CAVLC(Context Adaptive Variable Length Coding) are co-designed as hardware IP with software operation of the other modules in H.264/AVC codec. In order to increase the operation speed, a new method using SHIFT table is proposed. As a result, enhancement of about 16(%) in the operation speed is obtained. Designed Hardware IPs are downloaded into Virtex-4 FX60 FPGA in the ML-410 development board and H.264/AVC encoding is performed with Microblaze CPU implemented in FPGA. Software modules are developed from JM13.2 to make C code. In order to verify the designed Hardware IPs, Modelsim program is used for functional simulation. As a result that all Hardware IPs and software modules are downloaded into the FPGA, improvement of processing speed about multiples of 16 in case of DCT hardware IP and multiples of 10 in case of CAVLC compared with software-only processing. Although this paper deals with co-design of H/W and S/W for H.264, it can be utilized for the other embedded system design.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.11
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• pp.2285-2291
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• 2011

In this paper, H.264 high profile intra frame encoder, which integrates intra prediction, context-based adaptive variable length coding(CAVLC), and DDR2 memory control module, is proposed. The designed encoder can be operated in 440 cycle for one-macroblock. In order to verify the encoder function, we developed the reference C from JM 13.2 and verified the developed hardware using test vector generated by reference C. The designed encoder is verified in the FPGA (field programmable gate array) with operating frequency of 200 MHz for DMA (direct memory access), operating frequency of 50 MHz of Encoder module, and 25 MHz for VIM(video input module). The number of LUT is 43099, which is about 20 % of Virtex 5 XC5VLX330.

• Toxicological Research
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• v.35 no.4
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• pp.319-330
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• 2019

Adverse drug reactions (ADRs) constitute key factors in determining successful medication therapy in clinical situations. Integrative analysis of electronic medical record (EMR) data and use of proper analytical tools are requisite to conduct retrospective surveillance of clinical decisions on medications. Thus, we suggest that electronic medical recording and human genetic databases are considered together in future directions of pharmacovigilance. We analyzed EMR-based ADR studies indexed on PubMed during the period from 2005 to 2017 and retrospectively acquired 1161 (29.6%) articles describing drug-induced adverse reactions (e.g., liver, kidney, nervous system, immune system, and inflammatory responses). Of them, only 102 (8.79%) articles contained useful information to detect or predict ADRs in the context of clinical medication alerts. Since insufficiency of EMR datasets and their improper analyses may provide false warnings on clinical decision, efforts should be made to overcome possible problems on data-mining, analysis, statistics, and standardization. Thus, we address the characteristics and limitations on retrospective EMR database studies in hospital settings. Since gene expression and genetic variations among individuals impact ADRs, pharmacokinetics, and pharmacodynamics, appropriate paths for pharmacovigilance may be optimized using suitable databases available in public domain (e.g., genome-wide association studies (GWAS), non-coding RNAs, microRNAs, proteomics, and genetic variations), novel targets, and biomarkers. These efforts with new validated biomarker analyses would be of help to repurpose clinical and translational research infrastructure and ultimately future personalized therapy considering ADRs.

• 한국체육학회지인문사회과학편
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• v.57 no.1
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• pp.347-367
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• 2018

The purpose of this study is to explore the meaning of YangSaeng exercise as a recreational activity for older adults. Twelve older adults who participated in the 'YangSaeng Exercise' at the S Senior Welfare Service Center were interviewed through purposeful sampling method. Each participant was interviewed two times, and data were analyzed using Strauss and Corbin's(1988) grounded theory method. Centralization was appeared as 'An addiction to YangSaeng exercise' and causal conditions were appeared as 'Visiting Welfare Center' and 'Participation in YangSaeng exercise program' and situational context were appeared as 'Self-management of old ages' and 'For possession of Independent Life' as the results of Axial Coding. Moreover, arbitrational conditions were 'Coexistence of Regret and Attraction' and interaction strategies were appeared as 'Accept', 'Effort and Easing Mind' and 'Share Together'. As a result, 'Appreciation', 'YangSaeng Exercise that comes in my Life' and 'Softly Pitapat' were derived. Core category of 'Living Joyfully with comforted and eased' was selected through outline of story which means it contains Positivity and Expectations, Acceptance and Acknowledgement, Satisfaction and Appreciation, and Commitment and Hope. Based on the findings, we acknowledge that YangSaeng exercise plays a role in improving quality of life of older adults as a recreational activity. This study sheds light on the possibility of implementing 'YangSaeng Exercise' as a health promotion activity among older adults.

• The Journal of the Korea Contents Association
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• v.21 no.5
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• pp.324-337
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• 2021

This study examined the position and the characteristics of Korean writing textbooks in the rationales for writing education. Also, it explored the activities of writing knowledge formation based on the rationales in order to further propose some suggestions for the development of writing textbooks afterward. For this, it chose four Korean writing textbooks and presented the analyzed results through the processes consisting of material gathering, open coding, deep coding, expression and presentation as ones for the text qualitative analysis. First, it researched how the rationales such as formalism, cognitivism, and social constructivism were applied to and manifested in those textbooks. Furthermore, it examined how the language activities in the textbooks were shown from the four dimensions such as the knowledge of language structure, the process knowledge, the context knowledge, and the content knowledge; in particular, it focused on the content knowledge. It found out the results as follows. The rationales in structuring the chapters were not consistent with inner structures and contents. All the four writing knowledges were applied to each textbook; however, the emphasis and the proportion were different in each textbook. Also, it pointed out the textbook which contains diverse activities to be able to help the learners form the content knowledge and this sort of textbook is more effective from the perspective of social constructivism. Based on those results, it discussed several points which can be considered in the development and the selection of Korean writing textbooks later.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.42 no.5 s.305
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• pp.115-122
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• 2005

There are some problems in directly applying the conventional MPEG bit-stream based watermarking schemes to the bit-stream of a new compression standard, H.264/AVC. In this paper we analyze the effects of the conventional DCT-based watermarking scheme to H.264/AVC, especially in terms of image distortions and bit-rate changes. It turns out that the intra-frame prediction md CAVLC of H.264/AVC with the watermarking worsen the image distortions and bit-rate changes. The experiment results show on average 28.17dB decrease in PSNR and 56.71% increase in bit-rate over all QPs.

• Architectural research
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• v.16 no.2
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• pp.37-44
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• 2014

Utilizing spaces for awareness could be superficially noble. However, the typology of spaces played an important role in addressing the awareness of translating the messages through tangible forms, which in this context are sculptures. Assuring the efficacy of the typology of the spaces that is compatible with the content is important to ensure its timelessness to the dynamic demographical change of viewers. Therefore, the study proposes an investigation of the efficacy of typology of public urban space; garden that accommodates memorial sculptures. The study intends to analyze the features and flaws of ASEAN Sculpture Garden, as a mediatory role of ASEAN in instilling awareness of unity between ASEAN members to the public. The objective of the study is to analyze the efficacy of the garden to accommodate the rich memorial sculptures. The body of the research is formed by theoretical and case study research. It is projected by three methods; archival research, semi structured interviews and site documentation; direct observations and site visit. The qualitative data then will be analysed using Actor Network theory, keyword coding and site findings. Findings showed that as the main objective of the garden is to exhibit the sculptures, it could be summed up that it has failed to meet the apparent intention based on the site analysis conducted by the researcher. The typology of the space should be able to communicate the project's aims continuously rather than serving the function temporarily. The variables, which are space and time factors are debatable, as the neighboring tourist spot, National Monument residing the wide square managed to attract public attention due to its great efficacy of typological space regardless the time factor. As a conclusion, the typology of space is a huge factor to ensure the park's success.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10355-10361
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• 2015

Background: MicroRNAs (miRNAs) are small non-coding RNA molecules found in multicellular eukaryotes which are implicated in development of cancer, including cutaneous squamous cell carcinoma (cSCC). Expression is controlled by transcription factors (TFs) that bind to specific DNA sequences, thereby controlling the flow (or transcription) of genetic information from DNA to messenger RNA. Interactions result in biological signal control networks. Materials and Methods: Molecular components involved in cSCC were here assembled at abnormally expressed, related and global levels. Networks at these three levels were constructed with corresponding biological factors in term of interactions between miRNAs and target genes, TFs and miRNAs, and host genes and miRNAs. Up/down regulation or mutation of the factors were considered in the context of the regulation and significant patterns were extracted. Results: Participants of the networks were evaluated based on their expression and regulation of other factors. Sub-networks with two core TFs, TP53 and EIF2C2, as the centers are identified. These share self-adapt feedback regulation in which a mutual restraint exists. Up or down regulation of certain genes and miRNAs are discussed. Some, for example the expression of MMP13, were in line with expectation while others, including FGFR3, need further investigation of their unexpected behavior. Conclusions: The present research suggests that dozens of components, miRNAs, TFs, target genes and host genes included, unite as networks through their regulation to function systematically in human cSCC. Networks built under the currently available sources provide critical signal controlling pathways and frequent patterns. Inappropriate controlling signal flow from abnormal expression of key TFs may push the system into an incontrollable situation and therefore contributes to cSCC development.

• KIPS Transactions on Software and Data Engineering
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• v.3 no.8
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• pp.299-308
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• 2014

Various literatures related computing of information processing have been recently shown the researches inspired from the remarkably excellent human capabilities which recognize and categorize very complex visual patterns such as body motions and facial expressions. Applied from human's outstanding ability of perception, the classification function of visual sequences without context information is specially crucial task for computer vision to understand both the coding and the retrieval of spatio-temporal patterns. This paper presents a biological process based action recognition model of computer vision, which is inspired from visual information processing of human brain for action recognition of visual sequences. Proposed model employs the structure of neural fields of bio-inspired visual perception on detecting motion sequences and discriminating visual patterns in human brain. Experimental results show that proposed recognition model takes not only into account several biological properties of visual information processing, but also is tolerant of time-warping. Furthermore, the model allows robust temporal evolution of classification compared to researches of action recognition. Presented model contributes to implement bio-inspired visual processing system such as intelligent robot agent, etc.