• Title/Summary/Keyword: contamination process

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On the Microbial Contamination in Softdrink Manufacturing Process (청량음료의 미생물 오염에 대하여)

  • 김용배;이병국;유건희;조남선
    • Korean Journal of Microbiology
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    • v.11 no.3
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    • pp.129-133
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    • 1973
  • The authors have investigated about the microbial contamination of goods which is a criterion of hygienic control. Conducting on investigation, a special attention has been paid on the rate of microbial contamination in the goods, especially in manufacturing process of the softdrink. The authors also made an experiment on total microbes which is the criterion of contamination in each step of the process and in raw materials together with materials to be used for subdividing. Results obtained were as follows : 1) The orgin of microbial contamination was found in bottle cap and in tap water, that is, there appeared 9 colony per ml in bottle cap and 31-74 colony per ml in tap water, respectively. 2) It was found that microbial contamination are 4 colony per ml in average through year. However, it appeared 1 colony per ml in winter and 8 colony per ml in summer. 3) Coliform groups are not detected in goods through a year. 4) There was no variation in number of total microbes after ion exchange resin passage in purification process of tap water. 5) The number of microbes in goods are decreased when the raw materials are treated in high temperature short time (HTST) sterilization.

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A Survey on Microbial Contamination of Currently-Sold Drugs (I) -Bacterial contamination of marketed liquid- (시장의약품(市販醫藥品)의 미생물(微生物) 오염도(汚染度) 조사(調査) (제1보)(第1報) -시판내복액제(市販內服液劑)의 세균오염도(細菌汚染度)-)

  • Park, Young-Ju;Kim, Young-Il
    • Journal of Pharmaceutical Investigation
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    • v.3 no.4
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    • pp.5-15
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    • 1973
  • An investigation was carried out on a basis of the bacteriological examination with a view to detecting the degree of bacterial contamination for the 77 samples collected from the locally-sold liquid specialties. It's test period was 50 days from July 10 to August 30, 1971. Specially, the survey has put emphasis on the population of general bacteria and the identification of coli-form group, staphylococcus species, streptococcus species, bacillus species, fungi, and yeast species from liquid samples. The results obtained are summarized as follows; (1) For the 77 samples tested, the contamination of general bacteria was found out as minimun 0, i,e., maximum, $12{\times}10^4$ and the total average $45{\times}10^2$ per milliliter. (2) Although streptococcus species could not be detected with the samples, the contamination of the coli-form and staphylococcus species means the strong suggestion of the possibility of pathogenic bacterial contamination. (3) Specially, the products which stay in the neutral pH range and use suspending agents need to care for the microbial contamination in the manufacturing crocess. (4) It is thought necessary to perform the microbiological quality control in the liquid preparations only at least. (5) As the microbial contamination degree in the liquid decreases according to the elapse of time, the microbiological quality control will have to be carried out immediately after the completion of the manufacturing process in order to know the accurate degree. (6) The author thinks that the main reason of the microbial contamination in the liquid is the contamination during the manufacturing process. (7) For the purpose of prevention of the microbial contamination in liquid, therefore, it is more important to make efforts for the rationalization of manufacturing process, the improvement of equipment and environment, the specific training of workers for hygienic knowledges, etc. rather than the use of preservatives for the preparations.

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Priority Assessment for Groundwater Contamination Management Using Analytic Hierarchy Process (AHP) and GIS Approach (계층분석법(AHP)과 GIS를 이용한 고양시 일대의 지하수오염 관리우선순위 평가)

  • Lee, Moung-Jin;Hyun, Yunjung;Kim, Youngju;Hwang, Sang-Il
    • Journal of Soil and Groundwater Environment
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    • v.18 no.5
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    • pp.26-38
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    • 2013
  • In this study, priority for groundwater contamination management was assessed based on regional vulnerability in Goyang-si area, Gyonggi-do, Korea using analytic hierarchy process (AHP) and geographic information system (GIS). We proposed a concept for regional vulnerability to groundwater contamination with using socio-environmental vulnerability factors, which can be classified into three properties including regional hydrogeological property, contamination property, and groundwater use property. This concept is applied to Goyang-si area. For AHP analysis, an expertise-targeted survey was conducted. Based on the survey, a total of 10 factors (criteria) and corresponding weights for regional vulnerability assessment were determined. The result shows that regional contamination property is the most weighted factor among the three property groups (hydrogeological property: contamination property: groundwater use property = 0.3: 0.4: 0.3). Then, database layers for those factors were constructed, and regional vulnerability to groundwater contamination was assessed by weighted superposition using GIS. Results show that estimated regional vulnerability score is ranged from 22.7 to 94.5. Central and western areas of Goyang-si which have groundwater tables at shallow depths and are mainly occupied by industrial and residential areas are estimated to be relatively highly vulnerable to groundwater contamination. Based on assessed regional vulnerability, we classified areas into 4 categories. Category 1 areas, which are ranked at the top 25% of vulnerability score, take about 2.8% area in Goyang-si and give a high priority for groundwater contamination management. The results can provide useful information when the groundwater management authority decide which areas should be inspected with a high priority for efficient contamination management.

A Study on the 3-D Airflow and Dynamic Cross Contamination in the Photolithography Process Cleanroom (광식각공정이 있는 클린룸에서의 3차원 기류 및 동적교차오염에 관한 연구)

  • Noh, Kwang-Chul;Oh, Myung-Do;Lee, Seung-Chul
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.28 no.5
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    • pp.560-568
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    • 2004
  • We performed the numerical study on the characteristics of the 3-D airflow and dynamic cross contamination in the photolithography process cleanroom. The nonunifurmity, the deflection angle and the global cross contamination were used for analyzing the characteristics and performances of cleanroom. From the numerical results, we knew that the airflow characteristics of the cleanrooms are largely affected by the porosity of panel and the adjustment of dampers and the global cross contamination varies with the location of source and the passage of time through the concentration ratio.

A Numerical Study on the Characteristics of Airflow and Cross Contamination in the Photolithography Process Cleanroom (광식각공정 클린룸에서의 기류 및 교차오염에 대한 수치적 연구)

  • Noh, Kwang-Chul;Lee, Seung-Chul;Oh, Myung-Do
    • Proceedings of the KSME Conference
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    • 2003.11a
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    • pp.151-156
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    • 2003
  • We performed the numerical study on the characteristics of the airflow and cross contamination in the photolithography process cleanroom. The nonuniformity, the deflection angle and the global cross contamination were used for analyzing the characteristics and performances of cleanroom. We knew that the airflow characteristics of the cleanrooms are largely affected by the porosity of panel and the adjustment of dampers. And the numerical result showed that the global cross contamination varies with the location of source and the passage of time.

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Comparative Study of Particulate Contamination from Ampoule and Prefilled Syringe (앰플 및 1회용 주사용기에서의 미립자 혼입에 관한 비교연구)

  • Shim, Chang-Koo;Han, Yong-Hae;Kwon, Don-Sun
    • Journal of Pharmaceutical Investigation
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    • v.21 no.3
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    • pp.155-160
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    • 1991
  • Particulate is the foreign insoluble material in injectable solution inadvertently present in a given product. Considerable efforts have been made to avoid or minimize particulate contamination by pharmaceutical manufacturers during the production of parenteral products. Particulate contamination of the parenteral products can occur mainly during the opening (cutting) the container immediately before clinical use. In this study, particulate contamination generated during the opening process of ampoules (conventional type, 1-point and color-break ampoules) was compared with that of a prefilled injectable container (prefilled syringe). The particles were examined under a microscope after filtration of the total fluids in the containers. Particles having wide range of size distribution were found from all the ampoules tested. The contamination from the I-point ampoule and colorbreak ampoule was much less than from the conventional ampoule. Glass particles generated by cutting the glass-made ampoules seemed a principal source of the particulate contamination. The glass-partiaulte contamination could be improved substantially by replacing the ampoule containers with the prefilled syringe. Prefilled syringe, which can be used without any cutting process. did not generate particulates during the use. Therefore, it was concluded that prefilled syringe is most preferable container for the small volume parenteral (SVP) fluids in terms of particulate contamination.

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Effect of Yarn Characteristics on the Needle Contamination during Knitting Process

  • Koo, Young-Seok
    • Textile Coloration and Finishing
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    • v.22 no.1
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    • pp.8-13
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    • 2010
  • Needle contamination was investigated using a test rig simulated the knitting points in the knitting machine in relation with the characteristics of knitting yarn such as yarn type and moisture contents. When used open-end yarn compared with combed and carded ring-spun yarns, the needle contamination was significantly increased because of the higher friction between yarn and needle by the fly and other impurities. Also Lower moisture content of the yarns aggravated the needle contamination. In addition knitting yarn breakage was substantially influenced by the higher needle contamination.

Effects of ionized calcium on microbial cross-contamination in surface of carcass via slaughter process of chickens (이온화칼슘이 도계과정 중 도체표면의 미생물 교차오염에 미치는 영향)

  • Park, B.S.;Jin, J.Y.
    • Journal of the Korean Applied Science and Technology
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    • v.33 no.4
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    • pp.813-823
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    • 2016
  • The purpose of this study was to investigate the effects of ionized calcium treatment on total bacterial cross-contamination of chicken carcass surface in the slaughtering process. The growth of Escherichia coli was strongly inhibited in a medium prepared by using a 0.5% ionized calcium solution. The total bacterial cross-contamination of chicken carcass surface and the scalding water was significantly increased as the number of scalding was increased (p<0.05). The total bacterial cross-contamination of chicken carcass surface reached a plateau without a further increase as scalding was performed consecutively for 10 or more times. The total bacterial cross-contamination of the scalding water was significantly increased as the number of scalding was increased (p<0.05). The total bacterial cross-contamination of chicken carcass surface of the chickens raised on a floor type farm was significantly higher than that of the chickens raised in a battery cages (p<0.05). The total bacterial cross-contamination of chicken carcass surface of the chickens raised on a floor type farm was significantly lower in the 0.5% ionized calcium solution treatment group than in the control group (p<0.05).

An Off-site Screening Process for the Public in Radiation Emergencies and Disasters

  • Yoon, Seokwon;HA, Wi-Ho;Jin, Young-Woo
    • Journal of Radiation Protection and Research
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    • v.41 no.3
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    • pp.301-309
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    • 2016
  • Background: A contamination screening process for the local population in radiation emergencies is discussed. Materials and Methods: We present an overview of the relevant Korean governmental regulations that underpin the development of an effective response system. Moreover, case studies of foreign countries responding to mass casualties are presented, and indicate that responses should be able to handle a large demand for contamination screening of the local public as well as screening of the immediate victims of the incident. Results and Discussion: We propose operating procedures for an off-site contamination screening post operated by the local government for members of the public who have not been directly harmed in the accident. In order to devise screening categories, sorting strategies assessing contamination and exposure are discussed, as well as a psychological response system. Conclusion: This study will lead to the effective operation of contamination screening clinics if an accident occurs. Furthermore, the role of contamination screening clinics in the overall context of the radiation emergency treatment system should be clearly established.

The Effects of Organic Contamination and Surface Roughness on Cylindrical Capacitors of DRAM during Wet Cleaning Process

  • Ahn, Young-Ki;Ahn, Duk-Min;Yang, Ji-Chul;Kulkarni, Atul;Choi, Hoo-Mi;Kim, Tae-Sung
    • Journal of the Semiconductor & Display Technology
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    • v.10 no.3
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    • pp.15-19
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    • 2011
  • The performance of the DRAM is strongly dependent on the purity and surface roughness of the TIT (TiN/Insulator/ TiN) capacitor electrodes. Hence, in the present study, we evaluate the effects of organic contamination and change of surface roughness on the cylindrical TIT capacitor electrodes during the wet cleaning process by various analytical techniques such as TDMS, AFM, XRD and V-SEM. Once the sacrificial oxide and PR (Photo Resist) are removed by HF, the organic contamination and surface oxide films on the bottom Ti/TiN electrode become visible. With prolonged HF process, the surface roughness of the electrode is increased, whereas the amount of oxidized Ti/TiN is reduced due to the HF chemicals. In the 80nm DRAM device fabrication, the organic contamination of the cylindrical TIT capacitor may cause defects like SBD (Storage node Bridge Defect). The SBD fail bit portion is increased as the surface roughness is increased by HF chemicals reactions.