• Korean Journal of Pharmacognosy
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• v.44 no.1
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• pp.60-69
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• 2013

The worldwide prevalence and severity of allergic diseases including atopic and contact dermatitis has increased dramatically over the past decade, especially in developed countries. Mast cells are important effector cells in allergic reactions. The purpose of this study was undertaken to investigate the anti-allergic and anti-pruritic effects of Diospyros lotus leaf extract (DLE). DLE was prepared by extracting with distilled water. In the present study, we investigated the effect of DLE on the production of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-$1{\beta}$ (IL-$1{\alpha}$) and histamine in rat peritoneal mast cells (RPMCs), and on the skin lesion, leukocyte infiltration and scratching behavior in mice. Phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore A23187 significantly increased TNF-${\alpha}$ and IL-$1{\beta}$ production compared with media control. However, TNF-${\alpha}$ and IL-6 production increased by PMA plus A23187 treatment were significantly inhibited by DLE in a dose-dependent manner. DLE also inhibited the histamine release from RPMCs stimulated by compound 48/80, which promotes histamine release. Moreover, DLE administration had an inhibitory effects on the scratching behavior induced by pruritogen (compound 48/80, histamine) in ICR mice. Furthermore, DLE inhibited the skin lesions, inflammatory and mast cells in hairless mice sensitized by 2,4-dinitrofluorobenzene (DNFB). DLE administration reduced the IL-4 and IgE production induced by DNFB sensitization in hairless mice. These results suggest that DLE has a potential use as a herb medicine for treatment against allergy and pruritus-related disease.

• Journal of Oriental Neuropsychiatry
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• v.1 no.1
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• pp.81-93
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• 1990

On the Scholastic Achievement Test grads it was compared Chung Nam's with Cheon Puk by dividing a city, a farm village, a fishing village and a mountine village. The results were as follows ; 1. The regional difference of arerage grades were that the first is a large city, the second amiddle city, the third a mountine villgae, the fourth a fishing village, the last a farm village all the same Chung Nam and Cheon Puk. 2. The grades of acity and a farm of Chung Nam are higher then these of Cheon Puk. 3. Cheon Puk is higher than Chung Nam on a middle city, a mountine and a fishing's grades. 4. The characteristic was that the region of non benefits of civilization effect obstruction of intelligence less than a city mountine village. 5. It is considered that the obstruction of intelligence may diminish when eating marine products at a fishing village than a city-fishing village by side dish. From the above results, acknowledging a regional charater, it is suggested that improrement of food life imitate city shund sublate lest the physiological function of Bie Wee(脾胃) should converse a puthological state, get out of the food life civilization misled abnormal food life to normal. Systemic study must continue for maintaining of tradition of regional difference food life. By that manner excellent food life civilization may creat. Therefore it is recognized that experience accumulation of Oriental Medicine theory also close contact food life, so may make constent effort.

• Tribology and Lubricants
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• v.24 no.2
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• pp.63-71
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• 2008

Friction and adhesion tests were conducted to investigate tribological characteristics of materials for MEMS/NEMS using atomic force microscope (AFM). AFM Si tips were chemically modified with a self-assembled monolayer (SAM) derived from trichlorosilane like octadecyltrichlorosilane (OTS) and (1H, 1H, 2H, 2H-perfluorooctyl) trichlorosilane (FOTS), and various materials, such as Si, Al, Au, Cu, Ti and PMMA films, were prepared for the tests. SAMs were coated on Si wafer by dipping method prior to AFM tip to determine a proper dipping time. The proper dipping time was determined from the measurements of contact angle, surface energy and thickness of the SAMs. AFM tips were then coated with SAMs by using the same coating condition. Friction and adhesion forces between the AFM Si tip modified with SAM and MEMS/NEMS materials were measured. These forces were compared to those when AFM tip was uncoated. According to the results, after coating OTS and FOTS, the friction and adhesion forces on all materials used in the tests decreased; however, the effect of SAM on the reduction of friction and adhesion forces could be changed according to counterpart materials. OTS was the most effective to reduce the friction and adhesion forces when counterpart material was Cu film. In case of FOTS, friction and adhesion forces decreased the most effectively on Au films.

• Journal of Korean Society of Water and Wastewater
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• v.19 no.6
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• pp.819-826
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• 2005

To guarantee the disinfection ability in clearwell, a value of CT is considered where C[mg/l] is disinfectant residual at the exit of clearwell and T[min] means $T_{10}$, the contact time when 10% of tracer is out of clearwell after introducing the tracer at the inlet. To meet a CT value required, increasing the C value is not recommended because high C value can increase potential of producing disinfection by product like THMs. Increasing the hydraulic efficiency surrogated by $T_{10}$ is thus an option widely recommended. Right now, it is widely adopted estimating $T_{10}$ considering LW ratio only due to the suggestions of previous researches. The authors think however there are other factors to consider including shape, flow rate, configuration of inlet and outlet, and the existence of intra basin. This study is initiated to closely look at the effects of two factor on hydraulic efficiency. The factors are shape and inlet flow velocity, i.e., inflow. For that, computational fluid dynamics (CFD) model is developed and pilot test is also carried out. The results show that at a L/W ratio, disinfection ability is overestimated with larger length in shape and higher inlet flow velocity. This suggests that in determining $T_{10}$, the shapes of clearwell and inlet flow velocity should also be considered as well as L/W ratio.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.40 no.4
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• pp.344-350
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• 2004

This is the study on dry sliding wear behavior of unidirectional carbon fiber reinforced epoxy matrix composite at ambient temperature. The wear rates and friction coefficients against the stainless steel counterpart specularly processed were experimentally determined and the resulting wear mechanisms were microscopically observed. Three principal sliding directions relative to the dominant fiber orientation in the composite wear selected. When sliding took place against smooth and hard counterpart, the highest were resistance and the lowest friction coefficient were observed in the antiparallel direction. When the velocity between the composite and the counterpart went up, the wear rate increased. The fiber destruction and cracking caused fiber bending on the contact surface, which was discovered to be dominant wear mechanism.

• The Journal of Korean Academy of Prosthodontics
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• v.29 no.2
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• pp.1-16
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• 1991

In order to see the possible effect of the functional load-bearing after osseointegration of the titanium root form implant in dog a histologic study was conducted. One side of lower jaw was surgically prepared edentulousness and titanium implants were inserted. Some implants were functionally loaded through fixed detachable prosthesis and some are isolated and unloaded. The dog was sacrificed four months later and bone sections with implants were processed for histologic evaluation and the results were as follows ; (1) The bone to implant interface after four months of load bearing presented no mobility and no marginal bone loss radiographically and histologically. (2) The interface zone between compact bone and implant revealed a direct bone to implant contact and in some areas marrow tissue contacts were examined at the light microscopic level. (3) At the ultrastructural level the interface of surrounding compact bone matrix and implant, three types of superficial layers were found ; one with moderate electron dense amorphous granular substance layer, other with high electron dense fine granular substance layer, and another type of amorphous granular substance covered with high electron dense line of minute granules. (4) The osteoblasts in the marrow tissue neighboring implants and osteocytes in compact bone showed typical normal characteristics and in the marrow tissues some of lymphocytes and mast cells were observed. (5) The abscence of abnormal tissue reactions at a cellular level indicates a high degree of biocompatibility for the experimental titanium implant and basically no difference was found between functionally loaded and unloaded implants.

• The Journal of Advanced Prosthodontics
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• v.12 no.1
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• pp.22-32
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• 2020

PURPOSE. The aim of this study was to evaluate the microshear bond strength (µSBS) of four computer-aided design/computer-aided manufacturing (CAD/CAM) blocks repaired with composite resin using three different surface treatment protocols. MATERIALS AND METHODS. Four different CAD/CAM blocks were used in this study: (1) flexible hybrid ceramic (FHC), (2) resin nanoceramic (RNC), (c) polymer infiltrated ceramic network (PICN) and (4) feldspar ceramic (FC). All groups were further divided into four subgroups according to surface treatment: control, hydrofluoric acid etching (HF), air-borne particle abrasion with aluminum oxide (AlO), and tribochemical silica coating (TSC). After surface treatments, silane was applied to half of the specimens. Then, a silane-containing universal adhesive was applied, and specimens were repaired with a composite, Next, µSBS test was performed. Additional specimens were examined with a contact profilometer and scanning electron microscopy. The data were analyzed with ANOVA and Tukey tests. RESULTS. The findings revealed that silane application yielded higher µSBS values (P<.05). All surface treatments were showed a significant increase in µSBS values compared to the control (P<.05). For FHC and RNC, the most influential treatments were AlO and TSC (P<.05). CONCLUSION. Surface treatment is mandatory when the silane is not preferred, but the best bond strength values were obtained with the combination of surface treatment and silane application. HF provides improved bond strength when the ceramic content of material increases, whereas AlO and TSC gives improved bond strength when the composite content of material increases.

• Aerospace Engineering and Technology
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• v.12 no.2
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• pp.1-6
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• 2013

A LEO satellite transmits recorded images to a ground station using an X-band antenna during contact. The X-band antenna points to the ground station according to a TPF (tracking parameter file) during communication time. A TPF generation software generates azimuth and elevation profile which make the antenna point to the ground station using satellite orbit and attitude information and mission information including recording and downlink operation. When the satellite passes above the ground station, azimuth velocity increases rapidly so that jitter may occur if the azimuth velocity is in specific range. In case of realtime mission in which the satellite perform recording and downlink simultaneously, azimuth velocity must be lower than specific value to prevent image blur due to jitter effect. The method to point one virtual ground station has limitation of azimuth velocity reduction. In this paper, we propose the azimuth fixing method to reduce azimuth velocity of X-band antenna. The experimental results show that azimuth velocity of the X-band antenna is remarkably reduced using proposed method.

• Journal of the Korean Society of Safety
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• v.15 no.1
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• pp.140-145
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• 2000

This paper was composed with fatigue test of the cruciform specimens, as load carrying and non-load carrying type. It also has performed computational analyses for geometric condition of the fillet welding bead. As test results, the effect of stress ratio in the specimen was insignificant. Stress ranges were varied with R=0.1~0.2. The fatigue cracks that were found in the load carrying type specimens and most specimens welded with contact were developed at the end of welds. The fatigue strength of specimen that have fractured in maternal plate was found about ${\Delta}\sigma_c$=63.5MPa. It's about 24% less than that of the non-load carrying type specimens having about ${\Delta}\sigma_c$=83.8MPa. A category of the Fatigue design specifications which provide for cruciform details was defined grade C as a stress of the maternal member. And then, the fatigue strength to be transformed into the maternal stress was found about 78.27 MPa, it tends to be less than that of allowable fatigue strength.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.10 no.3
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• pp.99-106
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• 1990

This study was aimed to see the effect of chemical grout on fresh granite joint shear strength. The grouting chemical used in this study was composed of 25% water glass. Direct shear tests were performed on the chemical filled joints, which had been made artificially with granite. The test results show that chemical grouted rock jonts have markedly reduced shear strength comparing with the ungrouted fresh joints and they sheared within chemical grout before the rock to rock contact had been established, while the ungrouted joint sheared between rock surfaces from the beginning of shear deformation. With chemical grouted joints the shear stress slowly reached its maximum without showing distinct peak shear strength. Therefore the shear stiffness of joints were decreased with increasing thickness of grout. but the shear strain at failure was increased with it.