• 한국멀티미디어학회논문지
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• 제7권9호
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• pp.1329-1338
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• 2004

데이터마이닝은 방대한 데이터로부터 다차원적인 정보를 추출하는 것이다. 방대하게 구축되어 있는 데이터베이스에서 임의의 테이블의 컬럼에 대해 참조 할 수 있는 정보는 단순하게 컬럼명과 자료형 혹은 간단한 주석 정도이다. 그러한 비구조적이고 빈약한 내용만으로는 데이터마이닝을 위한 자료수집 및 자료탐색 단계에서 컬럼의 용도와 특성 및 스키마를 파악하여 데이터를 정제하고 수집하는 것이 난해 할 뿐만 아니라 너무 많은 시간이 소요된다. 이러한 문제를 해결하기 위해 본 논문에서는 관계형 데이터베이스 환경에서 데이터준비 단계 에 대부분의 시간을 소요하는 문제를 해결하기 위한 방안을 제안한다. 즉, 데이터 준비 단계에서 유용한 요소들을 메타데이터의 표준인 ISO/IEC : 11179 MDR (MetaData Registry) 규격에 맞는 표준 메타데이터를 제안하고, 이기종 및 이질 DBMS간에 호환 가능한 XML 기반의 분산 MDR 검색 시스템 구조를 제안한다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9797-9800
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• 2014

Background: Nasopharyngeal carcinoma (NPC) is a common cancer in Southern China and Southeast Asia. Alu elements are among the most prevalent repetitive sequences and constitute 11% of the human genome. Although Alu methylation has been evaluated in many types of cancer, few studies have examined the levels of this modification in serum from NPC patients. Objective: To compare the Alu methylation levels and patterns between serum from NPC patients and normal controls. Materials and Methods: Sera from 50 NPC patients and 140 controls were examined. Quantitative combined bisulfite restriction analysis-Alu (qCOBRA-Alu) was applied to measure Alu methylation levels and characterize Alu methylation patterns. Amplified products were classified into four patterns according to the methylation status of 2 CpG sites: hypermethylated (methylation at both loci), partially methylated (methylation of either of the two loci), and hypomethylated (unmethylated at both loci). Results: A comparison of normal control sera with NPC sera revealed that the latter presented a significantly lower methylation level (p=0.0002) and a significantly higher percentage of hypomethylated loci (p=0.0002). The sensitivity of the higher percentage of Alu hypomethyted loci for distinguishing NPC patients from normal controls was 96%. Conclusions: Alu elements in the circulating DNA of NPC patients are hypomethylated. Moreover, Alu hypomethylated loci may represent a potential biomarker for NPC screening.

• 건축역사연구
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• 제11권4호
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• pp.99-115
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• 2002

Centered on Durand and Le Corbusier, this study analyses the changing status of the grid and axis in modern architecture. In the Renaissance, the taxis grid operated as a contour grid, defining the elements and space of the building as part of closed harmonized world. In his Pre'cis des lec., ons d'architecture, Durand provides the most explicit demonstration of a new modem grid in which its lines function as spatial and structural axes. In principle these axes are coordinates for the placements of a priori elements but in Beaux-Arts practice, as Durand himself acknowledged, they involve a simultaneous process in which the spatial axis sets up the basic parti and the structural axis is developed into the building's poche'. As a coordinate, Durand's grid provides a place for the 'subject' to enter the architectural process. At the same time, it is the object of the subject's gaze, the dense site of the subject's transformative actions. Though Le Corbusier is noted for his frequent attacks on the academic system, his architecture should be seen within the continuity of the classical tradition. He redefines the Beaux-Arts axis as a moving and seeing observer, and continues the discipline of the plan, the essential discipline of the Beaux-Arts system. In his dialectics, an intellectual scheme which extends to his commentators, the intention and will of the subject must come in tune with the objective material form of the building. Like Durand, Le Corbusier's axis provides the medium for the subject to enter. Unlike the Beaux-Arts system, however, Le Corbusier's mobile subject no longer has a holistic view of the building previously provided by the central axis. If there is a parti for Le Corbusier, it consists of the domino grid as a potential, but nonetheless, tangible form. In comparison with the Beaux-Arts structural grid, his gaze no longer lingers on their lines because they no longer constitute a formal process tied to the development of a thick articulated structure. Le Corbusier's grid constitutes a 'loose' form, one that breaks down the hierarchical nature of the Beaux-Arts system.

• 동의신경정신과학회지
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• 제11권1호
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• pp.103-113
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• 2000

The aim of this study is to review the concepts of Jing(精) Qi(氣) Shen(神) Hun(魂) Po(魄) in the light of the Jungian psychology. According to the explanations of the Jungian psychology human beings have archetypes-a priori conditioning factors-in the collective unconscious. These archetyps are concerned with common concepts conceived by mankind about the fundamental elements which constitute the universe and the existence. The archetype is perceived in a symbol, hence Jing(精) Qi(氣) Shen(神) Hun(魂) Po(魄) also are these symbolic representations which had common background of mankind. The meaning of Jing(精) is emphasized as psychic and physical elements, and concerned with instinct. Qi(氣) corresponds to Jung's definition of libido as life energy. The concept of Shen(神) has the value of the self archetype as whole psyche's president principle. Hun(魂) and Po(魄) are intuitive notions of the Orient compared with Animus and Anima which are characteristic representations. However from a standpoint of autonomous energy as archetype the difference would be diminished. Considering each purpose of Hun(魂) and Po(魄) Hun(魂) has a intention of integrating the unconscious flux into consciousness while Po(魄) has a tendency toward instinct to secure a body. It is precious to recognize deeply that these concepts of jing(精) Qi(氣) Shen(神) Hun(魂) Po(魄) play an important part which mediate between the unconscious and consciousness, psyche and body as symbols.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5495-5501
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• 2013

Background: Alu elements are one of the most common repetitive sequences that now constitute more than 10% of the human genome and potential targets for epigenetic alterations. Correspondingly, methylation of these elements can result in a genome-wide event that may have an impact in cancer. However, studies investigating the genome-wide status of Alu methylation in cancer remain limited. Objectives: Oral squamous cell carcinoma (OSCC) presents with high incidence in South-East Asia and thus the aim of this study was to evaluate the Alu methylation status in OSCCs and explore with the possibility of using this information for diagnostic screening. We evaluated Alu methylation status in a) normal oral mucosa compared to OSCC; b) peripheral blood mononuclear cells (PBMCs) of normal controls comparing to oral cancer patients; c) among oral epithelium of normal controls, smokers and oral cancer patients. Materials and Methods: Alu methylation was detected by combined bisulfite restriction analysis (COBRA) at 2 CpG sites. The amplified products were classified into three patterns; hypermethylation ($^mC^mC$), partial methylation ($^uC^mC+^mC^uC$), and hypomethylation ($^uC^uC$). Results: The results demonstrate that the $%^mC^mC$ value is suitable for differentiating normal and cancer in oral tissues (p=0.0002), but is not significantly observe in PBMCs. In addition, a stepwise decrease in this value was observed in the oral epithelium from normal, light smoker, heavy smoker, low stage and high stage OSCC (p=0.0003). Furthermore, receiver operating characteristic (ROC) curve analyses demonstrated the potential of combined $%^mC$ or $%^mC^mC$ values as markers for oral cancer detection with sensitivity and specificity of 86.7% and 56.7%, respectively. Conclusions: Alu hypomethylation is likely to be associated with multistep oral carcinogenesis, and might be developed as a screening tool for oral cancer detection.

• 한국문헌정보학회지
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• 제54권2호
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• pp.105-125
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• 2020

본 연구는 2018년 전국도서관통계를 활용하여 공공도서관 방문자수 및 자료실이용자수에 미치는 영향요인을 log-log 중회귀모형으로 분석했다. 분석 결과를 요약하면 다음과 같다. 과거, '지식과 정보의 저장 및 전파'가 공공도서관의 주된 기능이던 시대에 이용자 유치에 가장 중요했을 것으로 생각되는 장서수나 좌석수 등의 요소를 넘어 현재는 문화 혹은 평생교육 프로그램, 도서관 운영, 이용자활동 등의 차원에서 매우 다양하고 복합적인 요소들이 방문자 및 자료실이용자 유인에 영향을 주고 있다. 이는 이제 도서관은 책이나 자료, 시설 등의 하드웨어적 요소보다는 문화 프로그램, 이용자 교육, 행사, 예산, 회원수, 개관시간, 건물의 스타일과 노후도, 동아리활동 등의 소프트웨어적 요소에 이끌려 찾아가는 종합문화센터가 되고 있다는 것을 뜻한다.

• 한국실내디자인학회논문집
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• 제14권3호
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• pp.181-190
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• 2005

In accordance with the rapid growth of digital media in 1990s, the state of indetermination that is found in digital process has been emphasized in the field of natural science and philosophy. Digitalized space design has been dramatically developed and it raised heated debate and comment on 'folded space' The purpose of this thesis is to explore how the cognitive-ecological factors constitute fold structures in space design of the late 20th century. Syntax of space structure and geometric composition were analyzed to define what types of cognitive-ecological factors are contrived in the process of visual information. In particular, I put higher theoretical emphasis on what characteristics are ensued in the process of structuring spaces than any other subjects. Through theses analyses and discussions, I raised questions on what principles are operating to create new space design that counts on non-linear structure and its formational process. And I also observed what influences these structural principles of design could fundamentally bring to human beings. First, I proposed that we could overcome reductionist space design through cognitive-ecological approach. Some key concepts such as affordance, parallel processing, and redundancy were adopted as defining elements of non-linear structures. As a result of analyses, I found that the cognitive-ecological approach could substitute the reductionist space design of the past. What is also found is that the three variables are the ultimate ecological elements. In addition, as a methodological concept of fold structures, the form of 'topology' was highlighted because it could be a supporting idea to the cognitive-ecological factors. Second, I claimed that non-linear design is more experiential than rational linear design, and it is more efficiently correspondent to human being than any other forms. What is intended and implied in non-linear structure is also indicated.

• 대한지리학회지
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• 제46권2호
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• pp.115-133
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• 2011

야마다의 산지차수구분법은 상향식으로 정의할 수 있는데, 이는 저차수 산지들이 모여 점차 차상위차수 산지를 이룸과 동시에 산지의 영역과 규모가 확대되기 때문이다. 하지만 산지를 총체적으로 이해하고 각종 산지 정보를 체계적으로 관리하기 위해서는, 특정 규모의 산지를 이루는데 기여한 차하위차수 산지만을 강조하는 야마다의 산지구분법에는 한계가 있다. 왜냐하면 상위차수 산지내에는 차하위차수 산지뿐만 아니라 독립된 차차하위, 차차차하위 산지도 포함되어 있기 때문이다. 이와 같은 문제점을 해결하기 위해 본 연구에서 제시된 산지분류법은 기본적으로 하향식이다. 여기서 하향식이란 최고위차수 산지를 구성하는 차하위차수 산지, 다시 이를 구성하는 차차하위차수 산지로 산지를 세분해나가 최종적으로 2차수 산지를 구성하고 있는 1차수 산지까지 분류해 나가는 것을 의미한다. 본 연구에서는 야마다 산지차수구분법을 근간으로 특정 산체를 구성하고 있는 모든 산지 요소를 체계적으로 분류하고 구분된 산지에 대한 새로운 명명법을 제시함으로써 산지정보의 종합적 체계적 관리를 위한 데이터베이스의 근간을 마련했다.

• 한국콘텐츠학회논문지
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• 제21권12호
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• pp.757-764
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• 2021

본 연구는 고레에다 히로카즈의 다큐멘터리 <이시부미>의 의미작용 구조와 신화적 의미에 대해 분석하고 있다. 즉, 스토리텔링을 구성하고 있는 기호적 요소들의 의미작용 구조에 관해 접근함으로써, <이시부미>가 함축하고 있는 신화적 의미를 폭넓게 살펴보는 것이다. 그것은 그가 추구하는 미학적 형식의 본질적인 특징을 살펴보는 것일 뿐만 아니라, 다큐멘터리 스토리텔링의 의미적 가치를 확대하는 미학적 유형을 분석하는 것이기도 하다. 특히, 고레에다 히로카즈는 <이시부미>에서 전형적이며 상징적인 요소를 스토리텔링 과정에서 조화롭게 활용하고 있으며, 그와 같은 이중적인 미학적 형식을 적용함으로써 시대적으로 요구되는 신화적 의미를 관객에게 효과적으로 전달하고 있다. 그러므로 <이시부미>는 신화적 의미를 발산하는 의미작용 체계이며, 그것은 관객의 상상력에 신뢰감을 가진 고레에다 히로카즈의 미학적 의도가 반영된 것이다.

• 자원환경지질
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• 제56권3호
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• pp.259-275
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• 2023

Pan African granitoids of Kaiama is comprised of K-feldspar rich granites, porphyritic granites, and granitic gneiss that are intruded by quartz veins and aplitic veins and dykes which trend NE-SW. In order to establish the geochemical signatures, petrogenesis, and tectonic settings of the lithological units, petrological, petrographical, and geochemical studies was carried out. Petrographic analysis reveals that the granitoids are dominantly composed of quartz, plagioclase feldspar, biotite, and k-feldspar with occasional muscovites, sericite, and opaque minerals that constitute very low proportion. Major, trace, and rare earth elements geochemical data reveal that the rocks have moderate to high silica (SiO₂=63-79.7%) and alumina (Al₂O₃=11.85-16.15) contents that correlate with the abundance of quartz, feldspars, and biotite. The rocks are calc-alkaline, peraluminous (ASI=1.0-<1.2), and S-type granitoids sourced by melting of pre-existing metasedimentary or sedimentary rocks containing Al, Na, and K oxides. They plot dominantly in the WPG and VAG fields suggesting emplacement in a post-collisional tectonic setting. On a multi-element variation diagram, the granitoids show depletion in Ba, K, P, Rb, and Ti while enrichment was observed for Th, U, Nd, Pb and Sm. Their rare-earth elements pattern is characterized by moderate fractionation ((La/Yb)_N=0.52-38.24) and pronounced negative Eu-anomaly (Eu/Eu^*=0.02-1.22) that points to the preservation of plagioclase from the source magma. Generally, the geochemical features of the granitoids show that they were derived by the partial melting of crustal rocks with some input from greywacke and pelitic materials in a typical post-collisional tectonic setting.