• Journal of applied mathematics & informatics
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• 제6권2호
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• pp.589-598
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• 1999

Classification errors are included in sampling -with -re-placement model where items are sampled from a Bernoulli process. Bayesian imperfect inspection model is considered. In addition con-jugate prior and predctive densities for imperfect inspection model are obtained.

• Bulletin of the Korean Chemical Society
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• 제29권7호
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• pp.1418-1420
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• 2008

• Bulletin of the Korean Chemical Society
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• 제26권7호
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• pp.1109-1111
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• 2005

• 대한수학회보
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• 제32권1호
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• pp.35-43
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• 1995

IF R is a left Artinian ring with identity, G is the group of units of R and X is the set of nonzero, nonunits of R, then G acts naturally on X by conjugation. It is shown that if the conjugate action on X by G is trivial, that is, gx = xg for all $g \in G$ and all $x \in X$, then R is a commutative ring. It is also shown that if the conjegate action on X by G is transitive, then R is a local ring and $J^2 = (0)$ where J is the Jacobson radical of R. In addition, if G is a simple group, then R is isomorphic to $Z_2 [x]/(x^2 + 1) or Z_4$.

• 한국미생물·생명공학회지
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• 제10권3호
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• pp.205-209
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• 1982

The enzyme-linked immunosorbent assay using the so-called "double-sandwich"technique was applied to determine Clostridium botulinum type F toxin. Polystyrene tubes were coated with horse anti-type F toxin serum and then toxin sample was added. The tubes were subsequently treated with rabbit anti-type F toxin IgG and sheep anti-rabbit serum IgG-horseradish peroxidase conjugate. By this technique, about 10 mouse intraperitoneal 50% lethal doses (ip LD/50/) of type F toxin could be detected. Low back-ground reading was achieved with the use of phosphate-buffered saline containing 0.05% Tween 20 and 1% bovine serum albumin as diluents of rabbit IgG and conjugate. Addition of EDTA in the diluents of toxin increased ELISA extinction value significantly. No cross-reaction was observed with botulinum type A and B toxin, but type E toxin gave sleight cross-reaction.

• Asian-Australasian Journal of Animal Sciences
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• 제32권7호
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• pp.1044-1051
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• 2019

Objective: Recent studies have implied that gene expression has high tissue-specificity, and therefore it is essential to investigate gene expression in a variety of tissues when performing the transcriptomic analysis. In addition, the gradual increase of long non-coding RNA (lncRNA) annotation database has increased the importance and proportion of mapped reads accordingly. Methods: We employed simple statistical models to detect the sexually biased/dimorphic genes and their conjugate lncRNAs in 40 RNA-seq samples across two factors: sex and tissue. We employed two quantification pipeline: mRNA annotation only and mRNA+lncRNA annotation. Results: As a result, the tissue-specific sexually dimorphic genes are affected by the addition of lncRNA annotation at a non-negligible level. In addition, many lncRNAs are expressed in a more tissue-specific fashion and with greater variation between tissues compared to protein-coding genes. Due to the genic region lncRNAs, the differentially expressed gene list changes, which results in certain sexually biased genes to become ambiguous across the tissues. Conclusion: In a past study, it has been reported that tissue-specific patterns can be seen throughout the differentially expressed genes between sexes in cattle. Using the same dataset, this study used a more recent reference, and the addition of conjugate lncRNA information, which revealed alterations of differentially expressed gene lists that result in an apparent distinction in the downstream analysis and interpretation. We firmly believe such misquantification of genic lncRNAs can be vital in both future and past studies.

• Journal of Microbiology and Biotechnology
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• 제26권4호
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• pp.784-789
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• 2016

We evaluated the synergistic antibacterial effect in combination with the chitosan-ferulic acid conjugate (CFA) and β-lactam antibiotics, such as ampicillin, penicillin, and oxacillin, against methicillin-resistant Staphylococcus aureus (MRSA) using fractional inhibitory concentration (FIC) indices. CFA clearly reversed the antibacterial activity of ampicillin, penicillin, and oxacillin against MRSA in the combination mode. Among these antibiotics, the combination of oxacillin-CFA resulted in a ΣFIC_min range of 0.250 and ΣFIC_max of 0.563, suggesting that the oxacillin-CFA combination resulted in an antibacterial synergy effect against MRSA. In addition, we determined that CFA inhibited the mRNA expression of gene mecA and the production of PBP2a, which is a key determinant for β-lactam antibiotic resistance, in a dose-dependent manner. Thus, the results obtained in this study supported the idea on the antibacterial action mechanism that oxacillin will restore the antibacterial activity against MRSA through the suppression of PBP2a production by CFA.

• 한국전산구조공학회논문집
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• 제24권4호
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• pp.405-412
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• 2011

본 논문에서는 켤레구배법을 이용해 전체-국부 확장함수를 지닌 일반유한요소법을 해석하는 방식을 제안한다. 이 기법은 편미분방정식의 해에 대한 정보가 충분하지 않은 경우에도 수치해석적인 방법으로 일반유한요소법의 확장함수를 구성할 수 있으며, 해석과정 중 약간의 추가적인 연산만으로 좋은 성능을 지닌 전처리행렬 및 초기 추측치를 구성할 수 있어 국부적으로 복잡한 거동을 보이는 문제의 해석에 효과적이다. 본 논문에 포함된 수치해석 예제의 결과는 제안된 기법이 가우스 소거법과 같은 직접 솔버를 이용하는 경우보다 수치해석적으로 더 효율적임을 보여준다.

• Bulletin of the Korean Chemical Society
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• 제31권11호
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• pp.3382-3384
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• 2010

A new synthetic route to ($\pm$)-aspidospermidine was devised, starting from the cycloadduct of 3-ethyl-5-bromo-2-pyrone with vinyl sulfide through a tandem conjugate addition-alkylation sequence. The requisite 3-ethyl-5-bromo-2-pyrone was prepared via the C3-selective Pd-catalyzed coupling reaction with $Et_3Al$-dimethylaminoethanol complex.

• 한국전산구조공학회논문집
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• 제23권6호
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• pp.693-702
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• 2010

In this paper, FETI(Finite Element Tearing and Interconnecting) method is introduced in order to improve numerical efficiency of Staggered method. The porous media theory, the Staggered method and the FETI method are briefly introduced in this paper. In addition, we account for the MPI(Message Passing Interface) library for parallel analysis, and the proposed combined Staggered method with FETI method. Finally Lagrange multipliers and CG(Conjugate Gradient) algorithm to solve decomposed domain are proposed, and then the proposed method is verified to be numerically efficient by MPI library.