• Bulletin of the Korean Chemical Society
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• v.32 no.2
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• pp.541-546
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• 2011

In this study, conjugate fibers were prepared from 1,4-cyclohexanedimethanol-modified polyethylene terephthalate (PET) resin using side by side conjugate spinning, sea-island type conjugate spinning, and split type conjugate spinning methods, and the properties of the conjugate fibers were investigated via several techniques. When viscosity increased, the tenacity of side by side conjugate fibers was increased, whereas elongation decreased. The sea-island conjugate fibers showed lower weight loss and surface color difference (K/S) values relative to that of regular PET fibers at the same conditions. The SEM results indicate that orange type spilt readily produced at a temperature range of 120 - 140$^{\circ}C$.

• Biotechnology and Bioprocess Engineering:BBE
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• v.11 no.3
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• pp.215-222
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• 2006

The Lowry method was used in this study to measure protein in Haemophilus influenzae type b (Hib) conjugate vaccines (polyribosylibitol phosphate-tetanus toxoid; PRP-TT) using deoxycholic acid (DOC) to induce protein precipitation. Trichloroacetic acid (TCA) did not induce precipitation adequately from the Hib conjugate bulk and the freeze-dried Hib conjugate product. Its yield was approximately 50%. The matrix structure of Hib conjugate inhibits precipitation by TCA. Although the Lowry method can be carried out without precipitation in Hib conjugate bulk when no residual impurities (adipic acid dihydrazide [ADH], 1-ethyl-3-(3-dimethylamino-propyl) carbodiimide-HCI [EDAC], phenol and cyanogens bromide [CNBr], etc.) are present, it cannot be used for Hib conjugate products that contain sucrose 8.5%, because 8.5% concentration of sucrose enhanced the protein concentration. DOC- and HCl-induced precipitation is an alternative method for evaluating the protein content of the Hib conjugate bulk and the Hib conjugate product. The precipitation was optimal with a final concentrate of 0.1% for DOC at $4^{\circ}C$ and pH 2. This Lowry method, using DOC/HCI precipitation to induce protein precipitation, was confirmed a consistent, reproducible, and valid test for proteins in Hib conjugate bulk and its freeze-dried product.

• Structural Engineering and Mechanics
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• v.65 no.4
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• pp.415-422
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• 2018

The Conjugate Finite-Step Length" (CFSL) algorithm is proposed to improve the efficiency and robustness of first order reliability method (FORM) for reliability analysis of highly nonlinear problems. The conjugate FORM-based CFSL is formulated using the adaptive conjugate search direction based on the finite-step size with simple adjusting condition, gradient vector of performance function and previous iterative results including the conjugate gradient vector and converged point. The efficiency and robustness of the CFSL algorithm are compared through several nonlinear mathematical and structural/mechanical examples with the HL-RF and "Finite-Step-Length" (FSL) algorithms. Numerical results illustrated that the CFSL algorithm performs better than the HL-RF for both robust and efficient results while the CFLS is as robust as the FSL for structural reliability analysis but is more efficient.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.17 no.4
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• pp.303-311
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• 2005

The problem of conjugate laminar film condensation of the pure saturated vapor in forced flow over a flat plate has been investigated as boundary layer solutions. A simple and efficient numerical method is proposed for its solution. The interfacial temperature is obtained as a root of 3rd order polynomial for laminar film condensation, and it is presented as a function of the conjugate parameter. The momentum and energy balance equations are reduced to a nonlinear system of ordinary differential equations with four parameters: the Prandtl number, Pr, Jacob number, $Ja^{\ast}$, defined by an overall temperature difference, a property ratio R and the conjugate parameter ${\zeta}$. The approximate solutions thus obtained reveal the effects of the conjugate parameter.

• Journal of the Korean Mathematical Society
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• v.60 no.3
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• pp.503-520
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• 2023

In this paper, using the theory of majorization, we discuss the Schur m power convexity for L-conjugate means of n variables and the Schur convexity for weighted L-conjugate means of n variables. As applications, we get several inequalities of general mean satisfying Schur convexity, and a few comparative inequalities about n variables Gini mean are established.

• Bulletin of the Korean Mathematical Society
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• v.35 no.4
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• pp.741-755
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• 1998

We prove the asymptotic lens equivalence in manifolds without conjugate points. By using this property we show that under a metric condition of asymptotically Euclidean and the curvature condition decaying faster than quadratic, any surface $(R^2,g)$ without conjugate points is Euclidean.

• Journal of the Chungcheong Mathematical Society
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• v.11 no.1
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• pp.143-150
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• 1998

In this paper, we investigate some properties of Jacobi fields and conjugate points in a complete Riemannian manifold M. Also we get a necessary and sufficient condition about a geodesic without conjugate points in the manifold with non-negative curvature.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.17 no.2
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• pp.191-199
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• 2005

Double pane window system, in which an air layer with a finite width is filled between glasses, is used in order to increase the insulation efficiency. In the present study, a conjugate heat transfer problem of a double pane window system has been studied numerically in order to investigate the effect of an air layer on the heat transmittance of the double pane window system using a finite element method based on P2P1 basis function. In this study on the conjugate heat transfer of a double pane window system, numerically predicted Nusselt numbers with or without conjugate heat transfer effect have been compared with an available existing empirical formula. It has been found that a Nusselt number from an existing formula for an enclosed space is different from that obtained from the present conjugate heat transfer analysis mainly due to the effects of a very high aspect ratio and conjugate heat transfer mechanism. Furthermore, it has been shown that the numerically estimated optimal air thickness of the double pane window system with conjugate heat transfer effect is a little bit longer than that obtained without considering conjugate heat transfer effect.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.272-272
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• 1994

신약개발에 있어서 대사연구는 약효의 species difference, 독성기전, 그리고 in vitro와 in vivo의 약효차이를 이해하는데 매우 중요한 역할을 담당하며 그 연구 영역을 넓혀가고 있다. 본 연구에서는 항혈전제로 개발 가능성이 있는 phosphodiesterase inhibitor인 KR30289의 rat과 rabbit에서 대사 연구를 통하여 약리효과의 상이점을 밝히고져 하였다. Mass analysis를 통하여 urinary 대사체의 구조를 규명한 결과 KR30289를 경구 투여 (1mg/kg)시 hydroxy derivative(M1)와 O-dealkylated derivative(M2)로 변환되어 urine으로 배설되었고 parent compound는 검출되지 않았다 M1과 M2 모두 free form, glucuronide conjugate, 그리고 sulfate conjugate 형태로 검출되었으나 rat과 rabbit 두 종간의 M1과 M2의 비율에서는 커다란 차이점을 보여주었다 rat의 경우 M2가 94% (free form : 14%, glucuronide conjugate 58%. sulfate conjugate, 22%)이었으며 rabbit에서는 M1이 54%로 상대적으로 많이 생성되었다(free form : 11%, glucuronide conjugate : 22%, sulfate conjugate 21%). 이와같이 두종간의 상이한 metabolic profile로 인하여 약리효과의 차이가 유발될수 있다고 추론된다.

• Fisheries and Aquatic Sciences
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• v.16 no.4
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• pp.229-235
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• 2013

In an effort to develop biopolymer-based antioxidant and antibacterial materials, a chitosan-phloroglucinol conjugate was prepared and cellular antioxidant activity and minimum inhibitory concentration against foodborne pathogens and methicillin-resistant Staphylococcus aureus (MRSA) evaluated. The chitosan-phloroglucinol conjugate showed higher antioxidant activities than the unmodified chitosan (P < 0.05). The chitosan-phloroglucinol conjugate showed 62.29% reactive oxygen species scavenging activity, 56.11% lipid peroxidation inhibition activity, and 2.21-fold increase of glutathione expression in mouse macrophage cells. Additionally, the chitosan-phloroglucinol conjugate exhibited higher antibacterial activities than the unmodified chitosan, and the chitosan-phloroglucinol conjugate showed fourfold higher antibacterial activities against MRSA and clinical isolates and twofold higher activities against foodborne pathogens compared to the unmodified chitosan.