• 고려인삼학회:학술대회논문집
• /
• 고려인삼학회 1980년도 학술대회지
• /
• pp.87-113
• /
• 1980

This experiment was carried out to evaluate the effects of Korean ginseng extract on carcinogenesis induced by various chemical carcinogens. Red ginseng extract was used for this study and was administered orally to the experimental animals. Carcinogens that were injected in subscapsular region of ICR newborn mice within 24 hours after birth were 9,10-dimethyl-1,2-benzan-thracene (DMBA), urethane, N-2-fluorenylacetamide(AAF), aflatoxin $B_1$ and tobacco smoke condensate. N -methyl-N -nitroso-N'-nitroguani-dine(MNNG) was injected subcutaneously at the back of wistar rats. Experimental animals were autopsied in immediately after being sacrificed. All major organs were examined grossly and weighted. After fixation histopathological preparations were made for microscopical study. Following results were obtained. In DMBA group sacrificed at the 26th week after the treatment with DMBA, the incidence of lung adenoma was $77\%$ and the average number of the tumor was 17. However, in DMBA combined with red ginseng group, the incidence was $78\%$ and the average number of lung adenoma was 14.1. This indicates that ginseng extract had no effect on the incidence of lung adenoma but decreased the average number of lung adenoma by $17\%.$ In DMBA group sacrificed at the 48th week after the injection of DMBA, the lung adenoma incidence was $88\%.$ The average diameter of the largest lung adenoma was 3.5 cm, the incidence of diffuse pulmonary infiltration was $18\%$ and the average lung weight of male experimental mice was $528.2{\pm}469.1\;gm.$ On the other hand, in DMBA combined with red ginseng group sacrificed at the 48th week, the incidence of lung adenoma was $96\%.$ The average diameter of the largest adenoma was 2.7 cm, the incidence of diffuse pulmonary infiltration was $7\%$ and the average lung weight of male mice was $418.0{\pm}520\;gm.$ These observations show that ginseng extract did not have any inhibitory effect on the incidence of lung adenoma but decreased the average diameter of the largest lung adenoma by $23\%,$ the incidence of duffuse pulmonary infiltration by $63\%$ and the average lung weight of male experimental mice by $21\%.$ From these results we have found that the prolonged administration with ginseng extract showed no inhibitory effect on the incidence of adenoma but it had the inhibitory effect on the proliferation of lung adenomas induced by DMBA. In urethane group sacrificed at the 28th week after the injection of urethane, the incidence of lung adenoma was $94\%$ and the average number of lung adenoma was 8.6. In urethane combined with red ginseng group, the. incidence of lung adenoma was $73\%$ and the average number of adenoma was 6.0. These results indicate that there were $22\%$ decrease of the lung adenoma incidence and $31\%$ decrease of the average number of adenoma in urethane combined with red ginseng group. And in urethane group sacrificed at the 50th week, the incidence of lung adenoma was $98\%$ and the incidence of diffuse pulmonary infiltration was $14\%$. In urethane combined with ginseng group the incidence of lung adenoma was $85\%$ and the incidence of diffuse pulmonary infiltration was $12\%$. Therefore the ginseng administration resulted in $15\%$ decrease of the lung adenoma incidence and $14\%$ decrease of the diffuse pulmonary infiltration incidence. From these results we knew that the prolonged administration with ginseng extract inhibited the incidence and also the proliferation of the lung adenoma induced by urethane. Lung adenoma and hepatoma were induced in the experimental mice sacrificed at the 68th week but not in the experimental mice sacrificed at the 28th week after the injection of AAF. In AAF group sacrificed at the 68th week after the injection of AAF the incidence of lung adenoma was $18\%$ and the incidence of hepatoma was $27\%$. And in AAF combined with ginseng group the lung adenoma incidence was $12\%$ and the hepatoma incidence was $37\%$. So the ginseng seemed to decrease the lung adenoma incidence by AAF, but we were unable to conclude the significant inhibitory effect of the ginseng extract on the incidence of lung adenoma by AAF because the above incidence of lung adenoma were similar to that of control group which was $11\%$. And these experimental data revealed that ginseng extract didn't have any inhibitory effect on the incidence of hepatoma induced by AAF. In aflatoxin $B_1$ group sacrificed at the 56th week, the incidence of lung adenoma was $24\%$ and hepatoma was $11\%$. However in aflatoxin $B_1$ combined with ginseng group the incidence of lung adenoma was $17\%$ and hepatoma was $3\%$ These results indicate that there were $29\%$ decrease of the lung adenoma incidence and $75\%$ decrease of the hepatoma incidence in aflatoxin $B_1$ combined with ginseng group. In tobacco smoke condensate experimental group sacrificed at 67th week, no tumors were induced except just a few lung adenoma. The lung adenoma incidence both in tobacco smoke condensate group and in tobacco smoke condensate combined with ginseng group was $8\%$. And this incidence rate was similar to that of control group. These results indicate that the injection of 320 ug tobacco smoke condensate per ICR newborn mouse was unable to induce lung adenoma in our experiments. In MNNG group sacrificed at the 27th week the tumor incidence was $38.5\%$ and in MNNG combined with ginseng extract group was $37\%$. In MNNG group for investigation of the life span of tumor bearing rats the tumor incidence was $93\%$ and the average life span of tumor bearing rats was 318 days. And in MNNG combined with ginseng extract group the tumor incidence was $96\%$ and the average life span was 337 days. Tumor induced by MNNG was almost sarcoma. This indicates that there was no inhibitory effect of ginseng extract on the tumor incidence, but the extract prolonged the average life span of tumor bearing rats by approximately 19 days.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2001년도 춘계학술대회논문집D
• /
• pp.343-347
• /
• 2001

Advanced Pressurized Reactor 1400(APR-1400), which is a standard evolutionary advanced light water reactor(ALWR), has been developed from 1992 as one of long-term Government Project(G-7). The APR-1400 is designed to operate at the rated output of 4000MWt to produce an electric power output of around 1450MWe. The balance of plant (BOP) for the secondary system consists of main steam, feedwater, condensate, turbine generator and auxiliary system. In this paper, we describe the major design features of secondary component, balance of plant configuration, and then the turbine cycle thermal performance evaluation using PEPSE code.

• 대한기계학회논문집B
• /
• 제22권6호
• /
• pp.750-756
• /
• 1998

In this study, condensation tests were conducted on a vertically finned plate (fin height 1 mm, fin thickness 1 mm, fin spacing 1 mm) using R-113. Results showed that fins enhanced the condensation on a vertical plain surface as much as four times. Comparison with theoretical models revealed that the effect off surface tension should be included in the model. The effect of interruption plates was also investigated. The plates were not effective in enhancing the finned plate condensation. The reason may be attributed to the already thinned condensate film on the finned surface.

• 설비공학논문집
• /
• 제12권9호
• /
• pp.817-824
• /
• 2000

The fluidized solid particles not only increase heat transfer rates but have a cleaning function eliminating contaiminated substances caused from condensate water. An experiment was performed to measure heat transfer rates and pressure drops in a fluidized heat exchanger with circulating solid particle for constant heat transfer rate. As a results, the heat transfer rate increased by 26.9~2.6%, heat transfer coefficient by 11.9~2.7%, and pressure drop by 79.1~10.9% at the gas velocity of 6.1 ~12.1 m/s and solid particle flow rate of 100~50 kg/h with the heat exchanger of H: 50 mm, $D_p=2 in,\; and\;D_{BP}$=30 mm.

• 멤브레인
• /
• 제7권1호
• /
• pp.1-10
• /
• 1997

A review is presented for various gas transport mechanisms through microporous membranes of both polymeric and inorganic materials. Different transport modes manifest depending on the pore size and the flow regime, which is a function of pressure, temperature, and the interaction between gas molecules and the pore walls. For microporous membranes whose pores are small and the internal surface area huge, the surface diffusion becomes a significant factor. If the pores become even smaller, then the transport mechanism will be more of an activated diffusion type. When conditions are right capillary condensation will take place to create an enormous capillary pressure gradient, which will greatly enhance the permeation flux. At the same time the capillary condensate of the heavier component may block the membrane pores denying the passage of the lighter gas molecules. All of these phenomena will influence the separation of mixtures.

• 한국원자력학회:학술대회논문집
• /
• 한국원자력학회 1996년도 춘계학술발표회논문집(2)
• /
• pp.88-94
• /
• 1996

The dependence of the node size in the condensation heat transfer coefficient for an inclined surface is eliminated and two correlations applicable for laminar and turbulent regimes are implemented in RELAP5/MOD3.1. The newly implemented correlations are used according to their applicable ranges of the film Reynolds numbers Reps which are calculated recursively to track the condensate film thickness along the condensation length. The modified version is compared with the original one through comparison with an analytical solution and the simulation of the Secondary Condensers (SC). It turns out that the simulation results by this modified version are independent of the node size and are better agreement with the analytical solution than those by the original one.

• 한국원자력학회:학술대회논문집
• /
• 한국원자력학회 1997년도 춘계학술발표회논문집(1)
• /
• pp.322-326
• /
• 1997

The condensate in a single vertical reflux condenser with a tube of the large L/D ratio could carried over in both ways of fill-and-dump and the annular occurrent to steam flow. From the experimental observation made, a theoretical model based on the lumped parameter method is made to understand the dynamics of the reflux condenser. The present model predicts well the time period of fill-and-dump model and the natural vibrational frequency of the water column. This could be a first step to understand the complex phenomena in the reflux condenser such as itd improved thermal performance due to the well controlled pulsation in steam flow and the tube-to tube effect in the multi tube reflux condenser.

• 한국콘크리트학회:학술대회논문집
• /
• 한국콘크리트학회 1995년도 봄 학술발표회 논문집
• /
• pp.94-99
• /
• 1995

Naphthalene sulfonated condensatd(NSF) has been widely using for the superplasticizing of ement and concrete. But NSF has a very large mobility loss with elapsed tiom. To retain mobility of NSF during a certain time, maleic anhydride and acrylic acid copolymer(MA) was polymerized and mixed with NSF in order to perpare admixture holding mobility-retention property of cement. By applying this admixture for ement paste, we examined the fluidity and mobility retention property as a function to elapsed time and measured the compressive strength of mortar with curing time. As a result, NSF containing 20wt% of MA showed very excellent fluidity and mobility-retention property. These properties were affected by the added amount of admixture and the ratio of water to cement.

• Fisheries and Aquatic Sciences
• /
• 제6권4호
• /
• pp.187-193
• /
• 2003

The performance of a foam fractionator to remove TAN, $NO_2,\;NO_3$, TSS, protein, and $PO_4-P$ at different superficial air velocities and foam overflow heights was evaluated in a lab-scale seawater recirculating system for culture of Korean rockfish (Sebastes schlegeli). The foam overflow rates increased with the increase of superficial air velocities, but decreased with the increase of foam overflow heights. Concentrations of all the water quality variables in the foam condensates increased with the increase of foam overflow height, but decreased with the increase of superficial air velocities. TSS, protein, and phosphate enrichment factors were within the range of 6.4-39.4, 1.6-7.3 and 1.2-3.9, respectively. Low values of TAN, $NO_2,\;and\;NO_3$ enrichment factors were obtained and they indicate that foam fractionation is rot an effective way to remove dissolved inorganic nitrogen. The calculated maximum daily removal values for TSS and protein were 10.9 and 1.4g, respectively.

• 한국막학회:학술대회논문집
• /
• 한국막학회 1995년도 제3회 심포지움 (분리막 연구의 최신동향)
• /
• pp.1-13
• /
• 1995

A review is presented for various gas tranport mechanisms through microporous membranes of both polymeric and inorganic materials. Different transport modes manifest depending on the pore size and the flow regime, which is a function of pressure, temperature, and the inateraction between gas molecules and the pore walls. For microporous membranes whose pores are small and the intenal surface area huge, the surface diffusion becomes a significant factor. If the pores become even smaller, them the transport mechanism will be more of an activated diffusion type. When conditions are right capillary condensation will take place to create an enormous capillary pressure gradient, which will greatly enhance the permeation flux. At the same time the capillary condensate of the heavier component may block the membrane pores denying the passage of the lighter gas molecules. All of these phenomena will influence the separation of mixtures.