• Journal of Pharmaceutical Investigation
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• v.41 no.1
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• pp.51-57
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• 2011

The objective of this study was to enhance the utilitization of Ibuprofen (IBU) by introducing the fast-disintegrating tablet (FDT) form. Presently, IBU is being widely used as a tablet or syrup form. But in contrast to these two formulations, IBU as FDT is not only convenient but also increases the control over the time release of the drug, noted by using Alginate beads. This study was carried out with Sodium Alginate and IBU at the ratios of 1:0, 1:0.5, 1:1, and 1:2 in order to produce a series of beads with different ratios. During the drying process of the beads, talc was added in beads to compare the effects with and without the talc. The final product was scanned with SEM imaging to determine the difference in the surface of the beads. The parameters assessed were the diameter, content assay, dissolution test and effectiveness of time-release. Direct compression method was used to prepare FDT containing IBU bead. The properties of FDT, such as hardness, disintegration time, were investigated. The dissolution profiles of FDT were tested using KP dissolution apparatus 1 (basket method). The results suggest addition of talc and drying the beads made the surface smooth and less vulnerable to clutter into chunks. The size of beads was less than 300 ${\mu}m$ which did not create a sandy feeling in the mouth. Thus, the beads formulation model made the sustained release of the drug possible, the hardness of FDT (1.25~1.50 $Kg/cm^2$) was acceptable and all the values of dissolving period were less than 30 seconds. The dissolution profile of FDT was same as that of IBU bead. The efficient dissolution profile and low price of IBU bead containing Sodium Alginate, the FDT formulation prepared from IBU bead can save the expenses and can improve the convenience of application of this drug.

• Journal of the Korea Institute of Military Science and Technology
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• v.7 no.4 s.19
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• pp.70-78
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• 2004

A study has been made to investigate the high temperature deformation behavior of Ti-6Al-4V alloyand to predict the final microstructure under given forming conditions. Equiaxed and $Widmanst\ddot{a}tten$ microstructures of Ti-6Al-4V alloys were prepared as initial microstructures. By performing the compression tests at high temperatures$(700\~1100^{\circ}C)$ and at a wide range of strain rates$(10^{-4}\~10^2/s)$, various parameters such as strain rate sensitivity(m) and activation energy(Q) were calculated and used to establish constitutive equations. When the specimens were deformed up to strain 0.6, equiaxed microstructure did not show any significant changes in microstructure, while $Widmanst\ddot{a}tten$ microstructure revealed considerable flow softening, which was attributed to the globularization of a platelet at the temperature range of $800\~970^{\circ}C$ and at the strain rate range of $10^{-4}\~10^{-2}/s$. To predict the final microstructure after forming, finite element analysis was performed considering the microstructural evolution during the deformation. The grain size and the volume fraction of second phase of deformed body were predicted and compared with the experimental results.

• The Journal of the Korea Contents Association
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• v.11 no.4
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• pp.92-100
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• 2011

In this paper, we propose a novel blind digital watermarking method based on a cellular automata transform (CAT). CAT is based on dynamic systems known as cellular automata(CA) and uses transform bases which are differently defined by a rule number, the number of neighbors, the number of cells, and an initial state, etc. The proposed CAT based method is compared with a blind watermarking method based on DWT which is commonly used for a domain transform in signal processing. We analyse properties on changes of DWT coefficients and CAT coefficients under various attacks and determine optimal parameters for a watermarking method robust to attacks. The simulations show that the watermarked images with high PSNR and MSSIM look visually identical to originals and are robust against most of typical image processing attacks. Moreover, the proposed CAT based watermarking method is superior to the DWT based one in robustness to most of typical image processing attacks including JPEG compression, median and average filtering, scaling, cropping, and histogram equalization.

• Journal of the Korean Institute of Gas
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• v.10 no.3 s.32
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• pp.34-40
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• 2006

This paper presents the optimized design of O-rings with a rectangular groove and dovetails, which are strongly related on the sealing performance of LPG filling unit. The computed results on the optimal design are analyzed by non-linear MARC finite element program with Taguchi method. O-rings with 4 different groove models are analyzed for 3 different elastomeric materials. The design parameters are given to polymer materials, groove depth, groove width, and diameter of O-rings. The FEM computed results showed that the affection ratios of O-ring diameter and material property are the most influential parameter among the groove width, groove depth, and compression ratio. Thus, this paper recommends model III for a rectangular groove and model IV for a dovetail groove with a given gas supply pressure of 1.764 MPa.

• Journal of Korean Society of Steel Construction
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• v.24 no.6
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• pp.711-723
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• 2012

Structural tests were performed to investigate the structural performance of concrete-filled steel tube column using different strength steels in their flange and web with high-strength steel HSA800 and mild steel SM490, respectively. The test parameters included the strength of column flange and infill concrete, and effect of concrete infill. Connection between different grade steels were welded using the electrode appropriate for mild steel and verified its performance. To evaluate the behavior of test specimens, eccentric loading tests were performed and the results were compared with the prediction by current design codes. Axial load and moment carrying capacity of test specimens increased with the yield strength of compression flange and weld fracture occurred after the specimen shows full strength. The prediction result for axial load-bending moment relationship and effective flexural stiffness gave good agreement with the test result.

• Journal of Korean Society of Steel Construction
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• v.25 no.6
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• pp.635-647
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• 2013

PSRC composite column is a concrete encased steel angle column. In the PSRC composite column, the steel angles placed at the corner of the cross-section resists bending moment and compression load. In the present study, using the performance criteria in KBC 2009, cyclic lateral loading test was performed for PSRC columns to verify the seismic performance. The test parameters were the column type, the use of continuous hoop, and the use of studs for steel angle. 2/3 scale specimens of a conventional composite column and three PSRC columns were tested. The test results showed that the load-carrying capacity predicted by KBC 2009 correlated well with the test results. The specimens also exhibited good deformation and energy dissipation capacities. After concrete cover spalling under cyclic loading, the load-carrying capacity were decreased by buckling of longitudinal bars and steel angles. When continuous hoop was used, the deformability of the PSRC column was improved, preventing early buckling of the steel angles.

• Tribology and Lubricants
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• v.31 no.5
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• pp.221-228
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• 2015

It is possible to prevent a piston from contacting the cylinder by changing the shape of the piston or by applying micro-textures, such as micro-grooves or micro-holes, over the piston surface. Usually, the minimum radial clearance reaches its minimum value at the beginning of the suction stroke because the pressure around the piston is low and almost axisymmetric such that the net pressure force on the piston is not sufficiently high to support the piston from touching the cylinder. In this study, we apply a series of saw-tooth-shaped grooves on the piston surface, and numerically investigate the effects of groove depth, groove angle, and the number of grooves with radial clearance variations using a finite difference method. We conduct a dynamic analysis of the piston for various changes in groove geometries to obtain the minimum radial clearance variation for the entire compression cycle. The minimum radial clearance increases while friction loss decreases when we apply the series of saw-tooth-shaped grooves on the piston. In addition, we analyze the impact of the change in the groove shape variable due to changes in radial clearance. Leakage variations are relevant to radial clearance, but have almost no effect on the groove parameters.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.16 no.2
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• pp.64-74
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• 2004

In order to accelerate the rate of consolidation settlement, to reduce settlement, and to increase bearing capacity for soft ground under quay wall, sand compaction pile method (SCP) has widely been applied. Improved ground is composite ground which is consisted of the sand pile-surrounding clayey soil. As caisson and upper structures are installed on SCP composite ground, the settlement is compositively occurred by elastic compression of sand compaction piles and also consolidation of the surrounding clay ground. In this study, the combined settlement model is proposed to predict the settlement of SCP composite ground in basis of elastic theory for sand compaction pile and consolidation theory for marine soft clay. Optimization technique was performed based on back-analysis so that real coded genetic algorithm was applied to estimate the parameters of the proposed settlement model. Case analysis was carried out for a domestic SCP composite ground to examine the applicability of the proposed prediction technique.

• Earthquakes and Structures
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• v.15 no.5
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• pp.453-462
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• 2018

Damages to buildings affected by a near-fault strong ground motion are largely attributed to the vertical component of the earthquake resulting in column failures, which could lead to disproportionate building catastrophic collapse in a progressive fashion. Recently, considerable interests are awakening to study effects of earthquake vertical components on structural responses. In this study, detailed modeling and time-history analyses of a 12-story code-conforming reinforced concrete moment frame building carrying the gravity loads, and exposed to once only the horizontal component of, and second time simultaneously the horizontal and vertical components of an ensemble of far-field and near-field earthquakes are conducted. Structural responses inclusive of tension, compression and its fluctuations in columns, the ratio of shear demand to capacity in columns and peak mid-span moment demand in beams are compared with and without the presence of the vertical component of earthquake records. The influences of the existence of earthquake vertical component in both exterior and interior spans are separately studied. Thereafter, the correlation between the increase of demands induced by the vertical component of the earthquake and the ratio of a set of earthquake record characteristic parameters is investigated. It is shown that uplift initiation and the magnitude of tensile forces developed in corner columns are relatively more critical. Presence of vertical component of earthquake leads to a drop in minimum compressive force and initiation of tension in columns. The magnitude of this reduction in the most critical case is recorded on average 84% under near-fault ground motions. Besides, the presence of earthquake vertical components increases the shear capacity required in columns, which is at most 31%. In the best case, a direct correlation of 95% between the increase of the maximum compressive force and the ratio of vertical to horizontal 'effective peak acceleration (EPA)' is observed.

• Steel and Composite Structures
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• v.36 no.2
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• pp.119-141
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• 2020

In this paper, wavy square absorbers were experimentally and numerically investigated. Numerical simulations were performed with LS-Dyna software on 36 wavy absorbers and their crushing properties were extracted and compared with the simple one. The effect of different parameters, including wave height, wave depth, and wave type; either internal or external on the crushing characteristics were also investigated. To experimentally create corrugation to validate the numerical results, a set of steel mandrel and matrix along with press machines were used. Since the initial specimens were brittle, they were subjected to heat treatment and annealing to gain the required ductility for forming with mandrel and matrix. The annealing of aluminum shells resulted in a 76%increase in ultimate strain and a 60% and 56% decrease in yield and ultimate stresses, respectively. The results showed that with increasing half-wave height in wavy square absorbers, the maximum force was first reduced and then increased. It was also found that in the specimen with constant diameter and half-wave depth, an increment in the half-wave height led to an initial increase in efficiency, followed by a decline. According to the conducted investigations, the lowe maximum force can be observed in the specimen with zero half-wave depth as compared to those having a depth of 1 cm.