• YAKHAK HOEJI
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• v.44 no.5
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• pp.478-487
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• 2000

This study was carried out to find new anti-tumor agent producing microbe and to characterize the anti-tumor agent produced from the microbe. Purified compound that has a high cytotoxicity against tumor cell-lines could be obtained from the broth culture filtrates of Streptomyces sp.409 strain isolated from soil in Korea. The in vitro cytotoxicity the in vivo evaluation of acute toxicity the safety assessment of the anti-tumor compounds and the taxonomic characteristics of the anti-tumor agent were measured. The antitumor compound 1 and 2 were obtained from the broth culture filtrates of Streptomyces sp.409 strain. The cytotoxicity of the compound 1 against tumor cell-line P388D$_1$ showed almost 4.5 times higher than that of adriamycin. However in the cytotoxicity against normal cell line Vero E6, adriamycin showed adversely 4 times higher than the compound 1 ($IC_{50}$/ value: 228.7 $\mu\textrm{g}$/$m\ell$). In comparison study with compound 1 and compound 2 in the in vitro cytotoxin productivity against tumor cell lines, $IC_{50}$/ value of the compound 1 was 0.25 $\mu\textrm{g}$/$m\ell$ in tumor cell line P388D$_1$and 0.53 $\mu\textrm{g}$/$m\ell$ in tumor cell-line L1210, and that of the compound 2 was 7.18 $\mu\textrm{g}$/$m\ell$ and 35.71 $\mu\textrm{g}$/$m\ell$, respectively; LD$_{50}$ value of the compound 1 in the in vivo acute toxicity in mice was 22.62 $\mu\textrm{g}$/kg body weight. These results suggest that compound 1 purified from Streptomyces sp. 409 has anti-tumor activity and will be developed as an anti-tumor drug.g.

• Journal of the Korean Applied Science and Technology
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• v.26 no.1
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• pp.18-23
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• 2009

Curing behavior and structural property of an inorganic compound added urea-formaldehyde(UF) and urea-melamine-formaldehyde(UMF) were studied. In addition, tensile strength and formaldehyde emission of plywoods made of those resin binders were studied. Curing temperature and structure were not changed, but tensile strengths of plywoods manufactured both with a UF resin and a UMF resin were decreased slightly as increased amount of inorganic compound. Formaldehyde emissions from plywoods were reduced as increased amount of inorganic compound. Wheat flour as an extender was helped to reduce of formaldehyde emission. From the result of this study it might be estimated that using appropriate amount of inorganic compound and proper resin system can be strengthened bond strength and reduced formaldehyde emission.

• Journal of Information Technology Applications and Management
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• v.11 no.4
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• pp.95-102
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• 2004

This paper proposes a method of segmenting compound nouns which include unregistered nouns into a correct combination of unit nouns using characteristics of person's names, loanwords, and location names. Korean person's name is generally composed of 3 syllables, only relatively small number of syllables is used as last names, and the second and the third syllables combination is somewhat restrictive. Also many person's names appear with clue words in compound nouns. Most loanwords have one or more syllables which cannot appear in Korean words, or have sequences of syllables different from usual Korean words. Location names are generally used with clue words designating districts in compound nouns. Use of above characteristics to analyze compound nouns not only makes segmentation more accurate, helps natural language systems use semantic categories of those unregistered nouns. Experimental results show that the precision of our method is approximately 98% on average. The precision of human names and loanwords recognition is about 94% and about 92% respectively.

• Mycobiology
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• v.42 no.3
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• pp.256-261
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• 2014

A ${\beta}$-glucosidase producing yeast strain was isolated from Korean traditional rice wine. Based on the sequence of the YCL008c gene and analysis of the fatty acid composition, the isolate was identified as Saccharomyces cerevisiae strain HJ-014. S. cerevisiae HJ-014 produced ginsenoside Rd, $F_2$, and compound K from the ethanol extract of red ginseng. The production was increased by shaking culture, where the bioconversion efficiency was increased 2-fold compared to standing culture. The production of ginsenoside $F_2$ and compound K was time-dependent and thought to proceed by the transformation pathway of: red ginseng extract ${\rightarrow}Rd{\rightarrow}F_2{\rightarrow}$ compound K. The optimum incubation time and concentration of red ginseng extract for the production of compound K was 96 hr and 4.5% (w/v), respectively.

• International Journal of Industrial Entomology and Biomaterials
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• v.16 no.2
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• pp.57-59
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• 2008

While searching for pancreatic lipase inhibitors, the active compound was found in a methanol extract of Apis mellifera venome. The active compound was isolated by Diaion HP-20 column chromatography, thin layer chromatography and HPLC. The active compound is stable to the extreme pH and heat. There is no loss of activity both in acidic and alkaline solution in the pH range of 2 to 11 by heating for 15 minutes at $90^{\circ}C$. The rf value of the compound was 0.51 at TLC with butanol : methanol: water (4:1:2) solvent system. The molecular weight of the compound was determined to be 293 by EI-MS.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.18 no.3
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• pp.1-8
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• 2010

A design study has been performed to obtain configuration and weight of a compound gyroplane. A study of research trends and characteristics was performed to develop the compound gyroplane sizing program. Based on these results, the sizing program has been developed and its suitability has been validated using existing compound gyroplane data. The subject air vehicles was a Challis Heliplane UAV, Carter Coptet, FB-1 Gyrodyne, and Jet Gyrodyne. As results, the program was suitable to size a compound gyroplane at conceptual design phase, because the greatest error rate was less than 10% and the conceptual design allowance error rate is less than 15%.

• Korean Journal of Materials Research
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• v.12 no.6
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• pp.427-430
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• 2002

Plasma nitrocarburizing treatment was performed for SCM 435 steel by using a plasma ion nitriding system. The effects of the variation of nitrogen and methan contents upon the hardened layer was investigated. Both the thickness of the compound layer and the amount of $\varepsilon$ phase in the compound layer increased with increasing nitrogen content. However, the thickness of the compound layer decreased due to unstable plasma for an atmosphere containing 90% $N_2$ gas content in the gas mixture. The amount of $\varepsilon$phase in the compound layer increased with increasing $CH_4$ gas content. For $CH_4$ gas content more than 2% in the gas mixture, the thickness of the compound layer decreased due to the formation of $\theta$ phase.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2000.11a
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• pp.291-294
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• 2000

Free-form surfaces arise in shipbuilding, automotive and aerospace industries. Specially compound free-form surfaces so do. Machining complicated products consist of compound surface, it is very important to avold and remove tool interferences. By the way, in compound surfaces the tool interference can occur not only in the tool path direction but also in the other direction. A new tool interference detection and correction using tool interference conditions is suggested to identify and correct the tool interference in compound surfaces.

• MALSORI
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• no.42
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• pp.25-36
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• 2001

Stress assignment has been much discussed in the literature on English compound nouns. The general view of the stress pattern of English compound nouns is that a main stress falls on the first element and a secondary stress on the second element; however, a stress pattern is often employed that provides counterevidence to the traditional pedagogical approach. A new idea is suggested by Ladd(1984) that 'compound stress represents the deaccenting of the head of the compound.' Recent studies show that initial stressing does not indicate compounds and syntactic phrases are not always characterized by final stressing. In his pilot test Pennanen comments on the frequent variation of stress patterns on individual items, on the basis of which Bauer confirms Pennanen's results with different informants. This paper is an attempt to justify Bauer's analysis with the same data as Bauer's and different subjects. It turns out that the competences of native-speaker informants do not rovide clear-cut answers. Some factors should be taken into account in assigning appropirate stress to compound nouns.

• Carbon letters
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• v.10 no.2
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• pp.101-108
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• 2009

Various silanes, amino silane, vinyl silane, TESPD, and ZS (TESPD/zinc soap complex), are added into chlorinated isobutylene-isoprene copolymer (CIIR)/hard clay/carbon black (CB) compound and they are investigated with respect to the vulcanization characteristics, the processability, and the mechanical properties. In hard clay/CB filled system, only ZS silane added compound shows both lower Mooney viscosity and extrusion torque while vinyl silane added compound showed only a lower extrusion torque. All the ZS added compounds showed the lowest viscosity among them. The silane added compounds showed an increased modulus. In 'fatigue to failure' count test, the ZS added compound showed superior counts compared to other silane (amino, vinyl, TESPD) added compounds. The mechanical properties were significantly increased when the S2 and ZS were added into CIIR/hard clay/CB compound. The ZS added compounds showed a significant improvement on elongation modulus.