• 제목/요약/키워드: component-based development

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Development of An Instrument to Measure Hope for the Cancer Patients (암환자 간호를 위한 희망 측정도구 개발)

  • 김달숙;이소우
    • Journal of Korean Academy of Nursing
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    • v.28 no.2
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    • pp.441-456
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    • 1998
  • The purpose of this study was to develop a reliable and valid instrument to measure hope for cancer patients in Korea. This Hope Scale(Kim & Lee Hope Scale ; KLHS ) was developed based on not only critical universal attributes explaining both basic hope (generalized hope) and specific hope but also particular characteristics varing from culture and situation, which were revealed in a comprehensive review of the literature. Initially 60 items were generated from three sources : 36 items from the Q-sample used in the Kim's study, 1992, 21 representative items(statements) from the rest Q-population of the above study, 3 items related to the newly discovered category in the new qualitative study using 10 open ended question(death and dying) from the new qualitative study on the 20 cancer patients. At first 3 items were eliminated by the critique of the content validity experts, who were high experienced nurse, nursing professors. And then 4 items were eliminated in consideration of corrected item total correlation coefficiency, theoretical framework of this study. After that, 14 items were eliminated in comparing two or three items identified with the same meaning in each factor by this research team with factor loading and communality. This Hope Scale was finally constructed with 39 items. Psychometric evaluation was done on 492 adults(104 cancer patients, 388 adults who imagined who were cancer patients ranging from 18 to 76 years old. The results revealed high internal consistency Alpha coefficiency of .9351. Princial Component Factor Analysis with Varimax Rotation resulted in 8 factors with more than 1.0 of Eigenvalue. Referring to Eigenvalues, percent of variances(>60%), reproduced correlation matrix, and our theoretical framework, we decided the eight factors were the best1 solution to represent hope dimensions sufficiently. The eight factors were "confidence in possibility of cure", "sense of internal satisfaction", "being in communion", "meaning of life", "Korean hope perspectives", "belief in god", "self confidence", "self-worth". Among these factors, "confidence in possibility of cure", "sense of internal satisfaction", "Korean hope perspectives" were identified as different hope dimensions from those of Nowotny Hope Scale and Herth Hope Scale. There was significant negative correlation of r=-.4736 between this hope scale and Beck Hopelessness Scale (BHS), and significant positive correlation of r=.3685 between this hope scale and Life Orientation Test (LOT) which indicate convergent and discriminant validity. The range of hope scores was from 71 to 244, with a mean of 171.97(SD=28.16).

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Discrimination model of cultivation area of Corni Fructus using a GC-MS-Based metabolomics approach (GC-MS 기반 대사체학 기법을 이용한 산수유의 산지판별모델)

  • Leem, Jae-Yoon
    • Analytical Science and Technology
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    • v.29 no.1
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    • pp.1-9
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    • 2016
  • It is believed that traditional Korean medicines can be managed more scientifically through the development of logical criteria to verify their region of cultivation, and that this could contribute to the advancement of the traditional herbal medicine industry. This study attempted to determine such criteria for Sansuyu. The volatile compounds were obtained from 20 samples of domestic Corni fructus (Sansuyu) and 45 samples of Chinese Sansuyu by steam distillation. The metabolites were identified in the NIST Mass Spectral Library via the obtained gas chromatography/mass spectrometer (GC/MS) data of 53 training samples. Data binning at 0.2 min intervals was performed to normalize the number of variables used in the statistical analysis. Multivariate statistical analyses, such as principle component analysis (PCA), partial least squares-discriminant analysis (PLS-DA), and orthogonal partial least squares-discriminant analysis (OPLS-DA) were performed using the SIMCA-P software package. Significant variables with a variable importance in the projection (VIP) score higher than 1.0 were obtained from OPLS-DA, and variables that resulted in a p-value of less than 0.05 through one-way ANOVA were selected to verify the marker compounds. Finally, among the 11 variables extracted, 1-ethylbutyl-hydroperoxide (9.089 min), nonadecane (20.170 min), butylated hydroxytoluene (25.319 min), 5β,7βH,10α-eudesm-11-en-1α-ol (25.921 min), 7,9-bis(2-methyl-2-propanyl)-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione (34.257 min), and 2-decyldodecyl-benzene (54.717 min) were selected as markers to indicate the origin of Sansuyu. The statistical model developed was suitable for the determination of the geographical origin of Sansuyu. The cultivation areas of four Korean and eight Chinese Sansuyu samples were predicted via the established OPLS-DA model, and it was confirmed that 11 of the 12 samples were accurately classified.

Development of the Accelerated Life Test Method & Life Test Equipment for the Counterweight of the Construction Machinery (건설기계용 카운터웨이트 시험장비 및 가속수명시험법 개발)

  • Lee, Gi-Chun;Lee, Young-Bum;Choi, Byung-Oh;Kang, Bo-Sik;Kim, Do-Sik;Choi, Jong-Sik;Kim, Jae-Hoon
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.39 no.12
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    • pp.1275-1280
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    • 2015
  • A large-sized exciter that vibrates a two-ton component is required to simulate the field operating conditions of a counterweight of an excavator. However, it is difficult for a small-medium sized company to obtain a large exciter for the life test of a counterweight which is an equivalent counterbalancing weight that balances a load. Therefore, in this study, we developed life test equipment for evaluating the reliability of construction machinery weighing about two tons. It simulates the field operating conditions using rotational vibrators consisting of electric motors. A failure analysis of the counterweight was also performed for the major components. Field data acquired from various sites were applied to the life test design of the counterweight. Finally, a zero-failure qualification test based on the accelerated life test was designed, and there was no failure during the test, which guarantees a life of $B_5$ 10,000 hours.

Field Applicability Evaluation Using Effective Microorganism Brewing Cycle for Contaminated Soil in Water Retention Basin (복합발효미생물을 이용한 하천유수지 오염토의 현장적용성 평가)

  • Shin, Eunchul;Jung, Minkyo;Kim, Kyeongsig;Kang, Jeongku
    • Journal of the Korean GEO-environmental Society
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    • v.17 no.11
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    • pp.35-43
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    • 2016
  • In this study, by using a Effective Microorganisms Brewing Cycle, it confirmed the purification effect of pollutants that are adsorbed on the basins stench removal and retarding soil. On the basis of on-site application test, a soil decontamination system will be suggested. Using a Effective Microorganisms Brewing Cycle, the odor concentration is reduced 2.5 times than that of natural purification treatment method. It was measured and found that the quality of the pore water discharged from the soil is improved. In addition, it was found that a composite of copper and lead with the fermentation microorganisms adsorbed on soil particles from the surface of the stirred experiments lagoon mixed soil is reduced to 65% and 66%, respectively, The TPH organic component was confirmed that the reduction effect of 85%. Restoration of reservoir contaminated soils using the effective microorganism brewing cycle needs to be more developed and implemented as a long-term purification system. This study may be a good reference of developing more complete microorganism brewing system which will efficiently reduce the odor and soil contamination based on optimal stirring and mixing ratio of the compound solutions and contaminated soils in reservoir.

Characteristics of Humidifier Disinfectant-like Products Containing NaDCC (sodium dichloroisocyanurate) and Their Use in Hospitals (NaDCC (sodium dichloroisocyanurate) 성분 가습기살균제 유사제품의 특성과 의료기관에서의 사용 사례)

  • Jo, Eun-Kyung;Han, Kyunghee;Ju, Min Jae;Yang, Wonho;Cho, Yoon-Hyeong
    • Journal of Environmental Health Sciences
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    • v.46 no.5
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    • pp.495-503
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    • 2020
  • Objective: This study aimed to compare the characteristics of humidifier disinfectant-like products (HD-like products) and humidifier disinfectant products (HD products) and introduce actual cases of the usage of HD-like products in hospitals based on an on-site investigation. Methods: The characteristics, chemical components, and usage of HD-like products (Hichlor or Biospot) and HD products (N-with) containing NaDCC (sodium dichloroisocyanurate) were compared. In the process of conducting the on-site investigation, four hospitals were identified as previously using HD-like products. Each on-site investigation to identify the use of HD-like products was composed of four parts: 1) hospital infection control guidelines, 2) manual for humidifiers in patient's rooms, 3) interviews with nursing staff, infection managers, and purchase managers, 4) searching on the product purchase system. Results: Although HD-like products (Hichlor and Biospot) and HD products (N-with) were sold for different usage purposes, they were all white-colored and coin-shaped foaming tablets with the same chemical component, NaDCC. The manual for using HD-like products and HD products was similar (inserting the tablet in a humidifier container with water). Among the four hospitals, one had used Hichlor in the same manner as HD (N-with) by inserting a tablet in 1L of water in a filled humidifier container and Biospot as a kind of detergent for humidifier container cleaning. Another two hospitals had used Biospot and/or Aniosyme as a kind of detergent for humidifier container cleaning. The other hospital had used unknown product in the same manner as N-with, so we thus assumed it was either an HD products (N-with) or HD-like products (Hichlor, Biospot). Conclusion: This study raises the possibility of the development of adverse health effects similar to exposure to an HD-products when exposed to an HD-like products and the possibility of further use in other medical institutions or multi-use facilities. Therefore, an expansion of the investigation is needed in order to confirm whether there have been similar cases in the past.

Fiber-optic biosensor for the detection of organophosphorus compounds in a contaminated water (Part I. : Design and development) (오염수 내의 유기인 화합물의 측정을 위한 광섬유 바이오센서 (제 1 부 : 장치 설계 및 개발 ))

  • Choi, Jeong-Woo;Min, Jun-Hong;Lee, Won-Hong
    • Journal of Sensor Science and Technology
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    • v.3 no.2
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    • pp.50-56
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    • 1994
  • Fiber-optic biosensor for the detection of organophosphorus compounds in a contaminated water was developed, which was the component of pesticides and agricultural agent. The detection principle of designed sensor was the pH variance induced by a reaction of acetylcholinesterase enzyme inhibited by organophosphorus compounds. The pH variance was detected by the optical system to measure the organophosphorus compounds. Litmus was selected as the pH-sensitive dye suitable to the enzyme reaction and a light source to be detected by the optical system. The enzyme entrapped in Ca-alginate gel was immobilized at the inner wall to maintain the high activity of enzyme and to be reused for a long period. The optical fiber was used to miniaturize and control remotely the sensor system. The He-Ne laser with 632 nm was selected as the light source to prevent light intensity fluctuation by the product. Cheap plastic optical fibers were used as the transmission part of the light and the phototransistor was used as the reception part of light based on the wavelength of He-Ne laser. The proposed fiber-optic biosensor has the linear analytical range of 0 ppm-1.5 ppm with response time of 5 minutes.

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Development of Serum-free Media for the Culture of Mouse Hybridoma (I) ; Determination of Optimal Media Composition (쥐 하이브리도마 세포배양을 위한 무혈청 배지개발( I ) -최적 배지성분의 결정-)

  • 조보연;최태부
    • Microbiology and Biotechnology Letters
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    • v.17 no.5
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    • pp.481-488
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    • 1989
  • A serum-free medium that could be used for the large-scale culture of mouse hybridoma to produce monoclonal antibodies was developed. The medium was based on a 1:1 mixture of Iscove's Modified Dulbecco's Medium and Ham's F-12, supplemented with insulin 10$\mu\textrm{g}$/$m\ell$, transferrin 10$\mu\textrm{g}$/$m\ell$, ethanolamine 10$\mu$M and selenium 30nM (designated EBM (enriched basal medium) with the supplements). The effect of various supplements of steroid hormones, vitamins, lipid and mineral salts was investigated and their optimal concentration was determined to replace fetal calf serum (PCS). These components were added respectively and then added by way of two or three combination to discern of which component combination was effective to the culture of hybridoma. As a result, serum-free medium KM3 (EBM with BSA 100$\mu\textrm{g}$/$m\ell$, mineral cocktail and 0.05% PEG) was deter-mined. The hybridoma Alps 25-3 cultured in this medium showed almost the same growth rate as in medium added with 2% fetal bovine serum. However, the antibody concentration from KM3 cultures was 80% of that obtained from culture with FCS. KM3 was also examined for the culture of other mouse hybridomas, KW, A4W & HCGK, and it was confirmed that it could support the growth of these hybridomas and the production of monoclonal antibodies.

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Space Structure Character of Hangeul Typography (한글 타이포그래피의 공간 구조적 특성)

  • Kim, Young-Kook;Park, Seong-Hyeon
    • The Journal of the Korea Contents Association
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    • v.8 no.3
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    • pp.86-96
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    • 2008
  • General development basis of letter system is recognized by formative value in terms of its function and structure. principle of clustered writing is the most significant feature of Hangeul typography as considered that it is based on function and formativeness. Thus, not only by changes with its form but also by its characteristic syllable combination, space structure is made as consonants and vowels are combined in single letter, then the combination develop into word, sentence, paragraph to make second, third space structure character. This character has significant impact on readability that is core function of typography. With this property, space structure character is regarded as very important component of Hangeul typography. First, space structure character of Hangeul typography is reviewed by relating it to visual perception of gestalt psychology and compared square-framed letter and framed latter By applying square-framed letter and framed latter in same sentence, legibility and readability were studied. Researcher has found that space structure character of Hangeul typography has significant impact on its function, and in terms of future design, it is very critical not only for design but also for communication environment as space structure formativeness of Hangeul typography interact with communication that is basic concept.

Design of V2I Based Vehicle Identification number In a VANET Environment (VANET 환경에서 차대번호를 활용한 V2I기반의 통신 프로토콜 설계)

  • Lee, Joo-Kwan;Park, Byeong-Il;Park, Jae-Pyo;Jun, Mun-Seok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.12
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    • pp.7292-7301
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    • 2014
  • With the development of IT Info-Communications technology, the vehicle with a combination of wireless-communication technology has resulted in significant research into the convergence of the component of existing traffic with information, electronics and communication technology. Intelligent Vehicle Communication is a Machine-to-Machine (M2M) concept of the Vehicle-to-Vehicle. The Vehicle-to-Infrastructure communication consists of safety and the ease of transportation. Security technologies must precede the effective Intelligent Vehicle Communication Structure, unlike the existing internet environment, where high-speed vehicle communication is with the security threats of a wireless communication environment and can receive unusual vehicle messages. In this paper, the Vehicle Identification number between the V2I and the secure message communication protocol was proposed using hash functions and a time stamp, and the validity of the vehicle was assessed. The proposed system was the performance evaluation section compared to the conventional technique at a rate VPKI aspect showed an approximate 44% reduction. The safety, including authentication, confidentiality, and privacy threats, were analyzed.

Development of Software Correlator for KJJVC (한일공동VLBI상관기를 위한 소프트웨어 상관기의 개발)

  • Yeom, J.H.;Oh, S.J.;Roh, D.G.;Kang, Y.W.;Park, S.Y.;Lee, C.H.;Chung, H.S.
    • Journal of Astronomy and Space Sciences
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    • v.26 no.4
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    • pp.567-588
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    • 2009
  • Korea-Japan Joint VLBI Correlator (KJJVC) is being developed by collaborating KASI (Korea Astronomy and Space Science Institute), Korea, and NAOJ(National Observatory of Japan), Japan. In early 2010, KJJVC will work in normal operation. In this study, we developed the software correlator which is based on VCS (VLBI Correlation Subsystem) hardware specification as the core component of KJJVC. The main specification of software correlator is 8 Gbps, 8192 output channels, and 262,144-points FFT (Fast Fourier Transform) function same as VCS. And the functional algorithm which is same as specification of VCS and arithmetic register are adopted in this software correlator. To verify the performance of developed software correlator, the correlation experiments were carried out using the spectral line and continuum sources which were observed by VERA (VLBI Exploration of Radio Astrometry), NAOJ. And the experimental results were compared to the output of Mitaka FX correlator by referring spectrum shape, phase rate, and fringe detection and so on. Through the experimental results, we confirmed that the correlation results of software correlator are the same as Mitaka FX correlator and verified the effectiveness of it. In future, we expect that the developed software correlator will be the possible software correlator of KVN (Korean VLBI Network) with KJJVC by introducing the correlation post-processing and modifying the user interface as like GUI (Graphic User Interface).