• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10057-10059
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• 2015

Positron emission tomography (PET) as the functional component of current hybrid imaging (like PET/CT or PET/MRI) seems to dominate the horizon of medical imaging in coming decades. $^{18}$Flourodeoxyglucose ($^{18}FDG$) is the most commonly used probe in oncology and also in cardiology and neurology around the globe. However, the major capital cost and exorbitant running expenditure of low to medium energy cyclotrons (about 20 MeV) and radiochemistry units are the seminal reasons of low number of cyclotrons but mushroom growth pattern of PET scanners. This fact and longer half-life of $^{18}F$ (110 minutes) have paved the path of a centralized model in which $^{18}FDG$ is produced by commercial PET radiopharmacies and the finished product (multi-dose vial with tungsten shielding) is dispensed to customers having only PET scanners. This indeed reduced the cost but has limitations of dependence upon timely arrival of daily shipments as delay caused by any reason results in cancellation or rescheduling of the PET procedures. In recent years, industry and academia have taken a step forward by producing low energy, table top cyclotrons with compact and automated radiochemistry units (Lab-on-Chip). This decentralized strategy enables the users to produce on-demand doses of PET probe themselves at reasonably low cost using an automated and user-friendly technology. This technological development would indeed provide a real impetus to the availability of complete set up of PET based molecular imaging at an affordable cost to the developing countries.

• Journal of Microbiology and Biotechnology
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• v.25 no.6
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• pp.782-787
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• 2015

In this study, we developed an assay system for missense mutations in human phenylalanine hydroxylases (hPAHs). To demonstrate the reliability of the system, eight mutant proteins (F39L, K42I, L48S, I65T, R252Q, L255V, S349L, and R408W) were expressed in a mutant strain (pah^-) of Dictyostelium discoideum Ax2 disrupted in the indigenous gene encoding PAH. The transformed pah - cells grown in FM minimal medium were measured for growth rate and PAH activity to reveal a positive correlation between them. The protein level of hPAH was also determined by western blotting to show the impact of each mutation on protein stability and catalytic activity. The result was highly compatible with the previous ones obtained from other expression systems, suggesting that Dictyostelium is a dependable alternative to other expression systems. Furthermore, we found that both the protein level and activity of S349L and R408W, which were impaired severely in protein stability, were rescued in HL5 nutrient medium. Although the responsible component(s) remains unidentified, this unexpected finding showed an important advantage of our expression system for studying unstable proteins. As an economic and stable cell-based expression system, our development will contribute to mass-screening of pharmacological chaperones for missense PAH mutations as well as to the in-depth characterization of individual mutations.

• The Journal of the Korea Contents Association
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• v.9 no.2
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• pp.76-87
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• 2009

The growth of CPU and communication technologies have made an important contribution to the development of the network-based intelligent service robots. Robot software must guarantee the correct execution and safety of the user. To achieve this, it is highly required to research how to guarantee the QoS of the components which organize a robot software. The QoS of robot components aims to execute the component stably by processing the data stream in a correct way. By guaranteeing QoS, we can achieve the intelligence and stability of robots. In this paper, we design and implement the QoS framework to guarantee the QoS of robot components on robot platforms with limited resources. We also measure the response times of QoS requests and present the performance analysis results about it.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.2243-2247
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• 2005

If a personal robot is popularized like a personal computer in the future, many kinds of robots will appear and the number of manufacturers will increase as a matter of course. In such circumstances, it can be inefficient, in case each manufacturer makes a whole platform individually. The solutions for this problem are to modularize a robot component (hardware and software) functionally and to standardize each module. Each module is developed and sold by each special maker and an end-product company purchases desired modules and integrates them. The standardization of a module includes the unification of the electrical, mechanical and software interface. In this paper, a few prototypes developed based on the concept of this study are introduced and possibility which can be standard platform is verified. Each prototype has merits and demerits, and a new structure of the hardware platform considered them is proposed Also the software architecture to develop the standardized and modularized platform is introduced and its detailed structure is described. The name of a method and the way to use that are defined dependently on the standard interfaces in order to use a module in other modules. Each module consists of a distributed object and that can be implemented in the random programming language and platform. It is necessary to study on the standardization of a personal robot after this steadily.

• Journal of the Korean Association of Geographic Information Studies
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• v.11 no.3
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• pp.1-12
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• 2008

This study was to develop the analyzing system for watershed characteristics data. The developed system has laid the foundation for preparing the input data in various hydrological models. The algorithms and items included in the system were derived from benchmarking of the GIS WEASEL, which used to prepare the input data of PRMS (Precipitation-Runoff Modeling System). The system was designed to develop and maintain the organized system using both object-oriented UML (Unified Modeling Language) and GIS component-based ArcObjects.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.3 s.357
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• pp.111-116
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• 2007

We have developed a passive millimeter wave (PMMW) imaging system with two-dimensional imaging arrays. For the imaging system we achieved single-substrate imaging-array element which include all necessary component such as Fermi tapered slot antenna (TSA), a balun, LNA's and a detector circuit on it. Two-dimensional arrays for real-time imaging at the 35 GHz band are currently under development. We will be able to make an advanced PMMW image system based on our system with the $2\times2$ imaging array in the near future.

• Korea Journal of Hospital Management
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• v.5 no.1
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• pp.1-23
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• 2000

This study was undertaken to develop performance measurement indicators in S Hospital, which is the largest component of Y Medical Center which implemented the Responsible Management System in 1993. To begin, strategic initiatives for S Hospital were reestablished based on Y Medical Center's goals and objectives. The BSC(Balanced Scorecard) was used to develop performance measurement indicators after validity checks by specialists. The results were that total 16 indicators were developed to measure performance for strategic initiatives. Those included the growth rate of patient revenues, operating profit to gross revenues, reduction rate in administrative expenses from a financial perspective; average medical expenses per adjusted patient, patient satisfaction survey for inpatients and outpatients and emergency room patients, return rate for treatment results from the customer's perspective; reduction rate in average length of hospital stay, expenses for lost cases of medical disputes, rate for contracted employees, the number of published reports per faculty member from an internal perspective; educational expenses for training medical staff and full time employees, adjusted patient per medical staff, and the number of cases implemented which were proposed by employees. Any organization needs to have its own explicit objectives to grow and develop and it is absolutely necessary to measure performance to accomplish them. The performance measurement indicators developed by this study are expected to be used as a tool to attain the objectives of S Hospital.

• Aerospace Engineering and Technology
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• v.11 no.2
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• pp.1-11
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• 2012

This paper describes the transmit/receive(T/R) module for the space based X-band active phased array radar. T/R module is the integrated module which is assembled by the transmitting and receiving RF semiconductor devices to enable the electronically beam steering of the phased array antenna and the key component of the SAR payload. T/R module can selectively receive the polarization signals by the switch according to the established technology but now the technological trend of the T/R module is to receive the horizontal and vertical polarization signal simultaneously. Therefore the research and development of the dual polarization receiving channel T/R module is actively in progress. In this study, as the prior research for the next generation SAR payload, the technological trend of the active phased array radar T/R module and the result of the preliminary design of the dual receiving channel T/R module were described.

• Journal of the Korean Institute of Intelligent Systems
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• v.15 no.6
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• pp.742-747
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• 2005

As the complexity of Web applications have increased significantly, the approach using frameworks such as Cocoon, Struts, JSF, is being suggested to develop Web applications more Quickly and efficiently. However, it Is difficult for beginners to write Apache Cocoon Sitemap files in XML. We implement a Cocoon Sitemap editor on the Java Servlet engine that allows beginners to write Cocoon Sitemap files more easily. Our system consists of three parts: Sitemap Main editor, Pipeline Viewer, and Sitemap Tracer. Sitemap Main editor support users to write BML configuration documents, so-called Sitemap file, that defines all the components pipelines, generators, and other configuration information for a Cocoon application. pipeline Viewer support users to catch the structure of Cocoon component pipelines by the medium of graphical interface. Sitemap Tracer have features to monitor of SAX events through Cocoon pipelines in a Sitemap file.

• 한국정보디스플레이학회:학술대회논문집
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• 2006.08a
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• pp.305-308
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• 2006

Advanced mobile communication devices require a bright, high information content display in a small, light-weight, low power consumption package. For portable applications flexible (or conformable) and rugged displays will be the future. In this paper we outline our progress towards developing such a low power consumption active-matrix flexible OLED $(FOLED^{TM})$ display. We demonstrate full color 100 ppi QVGA active matrix OLED displays on flexible stainless steel substrates. Our work in this area is focused on integrating three critical enabling technologies. The first technology component is based on UDC's high efficiency long-lived phosphorescent OLED $(PHOLED^{TM})$ device technology, which has now been commercially demonstrated as meeting the low power consumption performance requirements for mobile display applications. Secondly, is the development of flexible active-matrix backplanes, and for this our team are employing PARC's Excimer Laser Annealed (ELA) poly-Si TFTs formed on metal foil substrates as this approach represents an attractive alternative to fabricating poly-Si TFTs on plastic for the realization of first generation flexible active matrix OLED displays. Unlike most plastics, metal foil substrates can withstand a large thermal load and do not require a moisture and oxygen permeation barrier. Thirdly, the key to reliable operation is to ensure that the organic materials are fully encapsulated in a package designed for repetitive flexing, and in this device we employ a multilayer thin film Barix encapsulation technology in collaboration with Vitex systems. Drive electronics and mechanical packaging are provided by L3 Displays.