• 한국응용과학기술학회지
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• 제29권4호
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• pp.552-560
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• 2012

약물 전달 시스템은 약물의 방출 프로파일, 흡수, 분배 및 제품의 효율성과 안전성, 환자의 편의성과 협조를 향상시키기 위한 제거를 개선하는 명백하게 보호화된 공식화 기술이다. 가장 일반적으로 쓰이는 transdermal 시스템은 다양한 종류의 기술을 사용하는 skin patch다. 다른 투약 방법과 달리, transdermal 시스템은 장기간 사용이 가능하다. 또한, 부작용이 생길 경우, 약물 투약의 중단이 가능하다. karaya gum and locust bean gum(LBG)/water-soluble chitosan oligomer(WSCO)과 같은 Polysaccharide를 TDS의 기본 물질로 선택하였다. 또한, 이 polymers들은 tacrine 물질, 강화제로 규정되어진다. 이러한 polysaccharide 중에서, karaya gum matrix의 침투율은 lipophilic drug in vitro 와 같은 tacrine 내에서 가장 빠르다. 우리는 glycerin, PEG 400, and PEG 800를 강화제로 사용하였다. 그러므로, transdermal의 tacrine 흡수율은 vehicle 구성을 바꿈으로써, 혹은 침투 강화제를 사용함으로써 향상되었을 것이다. 특히, vehicle이 스스로의 효과를 강화하는 것과 더불어, vehicle에 강화제를 첨가함으로써 높은 침투 효율이 얻어질 것으로 기대된다.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2011년도 춘계학술대회 논문집
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• pp.808-813
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• 2011

There are hundreds of thousands call center workers wearing acoustic device. However, researches and noise exposure measurements on the noise transmitted from acoustic devices have seldom been performed due to the difficulty of measurement and to the absence of the measuring method in Korea. The aim of this study is to set up management measures to protect hearing loss on the call operator by acquiring measurement data of noise transmitted from the headset Noise exposure measurements of 17 operators were performed in 7 call centers and Head and Torso Simulator method in compliance with the ISO Standard 11904-2 was used for the measurement of noise transmitted from the headset Sound pressure levels(SPL) transmitted from the headset were 73.2~86 dB(A). The operator exposed to the highest SPL set up his volume control at 9 which was the highest volume level. The volume control level, adjustable from 1 to 9, could be identified 12 out of 17 operators and the range of volume levels was 4.5~9. As a result of Pearson Correlation Analysis, the correlation between volume level and SPL transmitted from the headset showed high relation as significance at the 0.672 level(p<0.05). To protect hearing loss of call center operators, it is more practical and effective measure to limit the volume level below the noise exposure level, i.e. 85 dB(A), rather than to carry out noise monitoring considering cost-effective aspect.

• 한국물환경학회지
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• 제18권3호
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• pp.327-336
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• 2002

Disinfection process in water treatment plants (WTPs) is one of the most important step in order to inactivate waterborne disease. However, what is the necessary disinfection in WTPs was not properly established in Korea. This study was conducted to evaluate disinfection performance in nationwide water treatment plants (n=474). Disinfection requirement based on the SWTR (Surface Water Treatment Rule) of the U.S. (1-log Giardia removal) was chosen in estimating the compliance. The scope of unit process for evaluating disinfection performance includes postdisinfection process in clearwells, pipeline, and storage tank. The worst water quality condition in individual WTPs was applied for the disinfection performance evaluation. The major results are as follows. First, it was appeared that 184 WTPs (39 %) provided insufficient disinfection performance. Disinfection performance was significantly improved during past 2 years. The ratio of the number of WTPs providing insufficient disinfection performance in 1999 and 2001 was 78 % and 41 %, respectively. One of major factors for this improvement was due to the improvement of $T_{10}/T$ value in clearwell, as a result of modification of clearwell facility. Second, if disinfection criteria is 3-log Giardia inactivation at worst water quality condition, then 19 % of all WTPs can not meet this disinfection criteria. And if disinfection criteria is strengthened to 4-log Giardia inactivation, then 58 % of all WTPs can not meet this disinfection criteria. Since disinfection criteria is decided by contamination level of Giardia in source water, it also needs the investigation of Giardia occurrence in source water.

• Tribology and Lubricants
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• 제31권4호
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• pp.141-147
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• 2015

Gas foil thrust bearings (GFTBs) have attractive advantages over rolling element bearings and oil film thrust bearings, such as oil-free operation, high speed stability, and high-temperature operation. However, GFTBs have lower load carrying capacity than the other two types of bearings owing to the inherent low gas viscosity. The load carrying capacity of GFTBs depends mainly on the compliance of the foil structure and the formed hydrodynamic wedge, where the gas pressure field is generated between the top foil and the thrust runner. The load carrying capacity of the GFTBs is very important for the suitable design of oil-free turbomachinery with high performance. The aim of the present study is to identify the characteristics of the load carrying performance of GFTBs. A new test rig for the experimental measurements is designed to provide static loads up to 800 N using a pneumatic cylinder. The maximum operating speed of the driving motor is 30,000 rpm. A series of experimental tests—lift-off test, static load performance test, and maximum load capacity test—estimate the performance of a six-pad GFTB, in terms of the static load, driving torque, and temperature. The maximum load capacity is determined by increasing the static load until the driving torque rises suddenly with a sharp peak. The test results show that the torque and temperature increase linearly with the static load. The estimated maximum load capacity per unit area is approximately 80.5 kPa at a rotor speed of 25,000 rpm. The test results can be used as a design guideline for GFTBs for realizing oil-free turbomachinery.

• 한국구조물진단유지관리공학회 논문집
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• 제16권5호
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• pp.11-18
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• 2012

철근콘크리트 구조물은 시간의 흐름과 환경의 변화에 의하여 노후화 및 부실화가 진행된다. 따라서 강도와 사용성이 저하되고, 결국에는 구조물 수명의 단축은 물론, 안전성도 줄어든다. 따라서 본 연구에서는 성능저하로 안전성이 떨어진 구조물의 내하력을 증진시키고, 기존 공법보다 내구성을 향상시켜서 구조물의 수명을 증가시키는 보강공법을 개발하고자 하였다. 이를 위해 보강재 양을 쉽게 조절할 수 있고 기존 콘크리트 구조물과 보강재를 일체화시킴으로서 하중재하 시에 보강재와 기존 콘크리트가 같이 거동할 수 있도록 진공함침을 이용하는 보강공법을 개발하였다. 휨 실험의 경우, 진공함침으로 2겹에 해당하는 보강, 섬유시트 2겹 보강, 진공함침으로 1겹 에 해당하는 보강, 섬유시트 1겹 보강, 무보강한 실험체의 순으로 최대강도를 보였다. 또한, 섬유보강재가 열악한 환경에 노출되었을 때의 내구성에 대한 확인결과, 모든 환경에 대한 잔류 인장강도가 90% 이상을 상회하였다. 이는 본 연구에 사용된 섬유보강재가 열악한 환경에 대해 저항성이 우수하기 때문으로 판단된다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.357-358
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• 2013

The non-linear characteristics of ON states are important for the application to the high density cross-point memory industry because the sneak current in neighbor cells occurred during reading, erasing, and writing process. Kw of above 20 in ON states, which is the writing current @ Vwrite/the current @ 1/2Vwrite, was required in cross-point ReRAM memory industry. The high current density non-linear IV curve of ZnSe selector was shown and the ALD HfO2 switching device has the linear properties of ON states and the compliance current of 100 uA. To evaluate the performance of the selection device, we connected itto HfO2 switching device in series. The bottom electrode of the selection device was connected to the top electrode of the RRAM. All of the bias was applied with respect to the top electrode of the selection device, whereas the bottom electrode of the RRAM was grounded. In the cross-point application, 1/2Vwrite and -1/2Vwrite were applied to the word-line and bit-line, respectively, which were connected to the selected cell, and a zero bias was applied to the unselected word-lines and bit-lines. The current @ 1/2Vwrite of the unselected cells was blocked by the selection device, thus eliminating the sneak path and obtaining a writing voltage margin. Using this method, the writing voltage margin was analyzed on the basis of the memory size.

• 대한의용생체공학회:의공학회지
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• 제41권1호
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• pp.8-13
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• 2020

To develop cardiovascular simulator capable of implementing pulse waves similar to the human body, accurate information about reflection wave is required. However, the conclusion is still not clear and various discussions are underway. In this study, the pulse wave velocity of the tube used in the experiment was first determined by measuring the pressure waves at two points in a single tube system with the experimental device to implement the pulse wave transmission of blood vessels, and the superposition time and characteristics of the reflection wave were confirmed. After that, an air chamber was set at the reflection site, and the effect of the change of air volume on the reflection wave was investigated. Finally, the effect of the number of branches connected to a single tube on the reflection wave was investigated. The superposition time of the reflection wave can be controlled by the air volume of the air chamber, and the magnitude of the reflection wave is influenced by the number of reflection sites that generate the reflection wave. The results of this study may be of practical assistance to simulator researchers who want to implement pulse wave similar to clinical data. It is expected that the more results similar to clinical are provided, the greater the scope of the simulator's contribution to clinical cardiovascular research.

• 기본간호학회지
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• 제9권2호
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• pp.165-179
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• 2002

Purpose: This descriptive study was done to evaluate the attitude and practice of hand-washing by student nurses. Method: The subjects of the study were 463 senior and junior undergraduate student nurses and RN-BSN students. The questionnaire was developed by the researchers Data were collected from Oct. 16 to Dec. 20. 2001. and analysed by SPSS/WIN. General characteristics. attitude and practice were analyzed by frequency and percentage and differences in attitude and practice according to grade and practice setting were analyzed with $x^2$ test, t-test or ANOVA. Result: 1) The mean frequency of hand-washing was 6.63. Senior students washed more frequently than junior students. 2) The reasons for non-compliance were 'not being accustomed', 'forgetting', and 'not accessible'. 3) The mean time for hand-washing was 23.79 sec., less than the stated appropriate time of 42 18 sec. 4) 90% of the students washed their hands 'after contacting excretions and contaminated items' and few washed 'before giving care to the client'. 5) Most students washed hands rotationally rubbing with soap and water. 6) While washing, they removed their rings more often than their watches. 7) Soap bar (52.8%) and paper towel (69.6%) were most frequently used as decontaminating agent and drying method, but detergent solution (74.2%) and paper towels (60%) were considered as the most appropriate agent and method. 8) Hand-washing was perceived important generally 'to protect from cross-infection'. 'to protect one-self' and 'the most cost effective'. 9) All students responded nurses should practice 'hand-washing.'

• 전자공학회논문지S
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• 제36S권10호
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• pp.83-93
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• 1999

MPEG-2 비디오 표준에서는 다양성을 보장하기 위하여 많은 변수들을 조절할 수 있다. MPEG-2 비트열을 통하여 전송되는 이러한 변수들이 MPEG 비디오 디코더에서 올바르게 해석되어, 전송한 것과 동일한 영상이 수신기에서 재생되는지 확인하여야 한다. 본 논문에서는 검사할 디코더의 최정화면을 관측하여 MPEG 비디오 디코더의 정상 동작 여부를 간편하게 확인할 수 있도록 검사용 비트열을 설계하는 방식을 제안하였다. 제작된 비트열의 내부는 두 부분으로 구성된다. 하나는 검사할 변수를 변화시키며 검사 패턴을 만드는 부분이고, 다른 하나는 MPEG의 움직임 보상과 discrete cosine transform(DCT) 계수를 이용하여 이전 프레임에서 만들어진 검사 패턴을 상쇄시키는 부분이다. 이러한 원리를 적용하여 검사용 비트열을 제작하였고 스프트웨어 디코더로 분석한 결과를 제시하였다.

• 대한간호학회지
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• 제47권5호
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• pp.613-623
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• 2017

Purpose: This study was conducted to identify the effects of education regarding action plans according to a self-monitoring program on self-management adherence, knowledge, symptom control, and health-related quality of life (HRQoL) among adults with asthma. Methods: Thirty-four patients were randomly assigned to the intervention group and thirty-two to the control group in this study. A tailored 50-minute intervention based on the contents of self-monitoring and action plans developed by the National Heart Lung and Blood Institute was provided to the intervention group. Structured and well developed questionnaires were used to measure the dependent variables. Results: There were no differences in all general and clinical characteristics, and the dependent variables between two groups in the pre-test. In the post-test, there were differences in the level of self-management adherence (t=4.41, p<.001), knowledge (t=2.26, p=.027), symptom control (t=-2.56, p=.013), and total HRQoL (t=2.14, p=.036) between the two groups, although there was a difference only in the sub-domain of emotion (t=2.03, p=.047) in HRQoL. Conclusion: This study found that action plans according to self-monitoring that enhance a participatory interaction in the treatment and care could help patients with moderate to severe asthma to engagead equately in self-care, to control their symptoms, and to improve their HRQoL. Further studies are still needed to identify longitudinal effects of this program.