• 한국결정성장학회지
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• 제26권5호
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• pp.209-214
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• 2016

Foam reaction injection molding (FRIM) is a widely used process for manufacturing polyurethane foam with complex shapes. Numerical model for polyurethane foam forming reaction during FRIM process has been intensively investigated by a number of researchers to precisely predict final shapes of polyurethane foams. In this study, we have identified a problem related with a previous theoretical model for polyurethane foam forming reaction. Thus, previous theoretical model was modified based on experimental and computational results.

• Asian Journal of Innovation and Policy
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• 제8권2호
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• pp.180-207
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• 2019

This article explores the historical evolutionary process of the biopharmaceutical industry of Korea, and how intentional and unintentional policy interventions have triggered the creation of the industry's system dynamics and paved the way for the generation of a few global leading products, including biosimilar, as well as next-generation therapeutics of gene and cell. The policies cover the simple technology transfer of API synthesis to overcome the endemic parasitic disease, new substance patent adoption and new drug development consortia, human resource development, various national initiatives influenced by the Human Genome Project, and venture promotion schemes. The scope and implementation tools under these policies have been aligned and refined to transform traditional fine chemical-based pharmaceuticals, to stimulate large companies' participation and to create technology-based venture companies in the biopharma business of Korea.

• 한국안전학회지
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• 제27권5호
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• pp.171-178
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• 2012

Shipbuilding is basically labor-intensive industry. It creates a number of job opportunities, but it is classified as a high risk industry like the construction industry. Shipyards show similarities in many aspects compared with the construction sites. There are many stakeholders of the HSE managements in the shipbuilding industry, such as ship owner, primary contractor and multi-layered subcontractors. The ship owners who are almost foreigners are treating strictly about safety and health. Therefore, it is necessary to development an appropriate HSE management systems and for the management systems it is desirable to information technology (IT) to accommodate these complex and complicated problems and situations. It was developed the ISP (Information Strategic Planning) as a HSE management system for the shipbuilding industry. It consisted of the environment analysis, the As-Is analysis and the To-Be design. In this study, the ISP is introduced and further it is suggested that it should be connected to system of HR(Human resource), PM(Plant maintenance) and KM(Knowledge Management) to make the HSE management system efficient.

• 대한안전경영과학회지
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• 제25권2호
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• pp.113-120
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• 2023

Occupational safety and health management expenses in the construction industry are statutory and separately included in the cost statement to prevent occupational accidents and health problems. The expenses are determined by multiplying the standard amount by the rate decided according to construction types and scales. However, the current expense appropriation method does not properly reflect the recent changes in the construction industry such as industry size, industry diversification, and social atmosphere about safety reinforcement. This study surveyed 1579 questionnaires in total and analyzed expense execution rate and proportion of each expense category. The expense execution rate was relative higher in complex construction (e.g., heavy construction = 126%, civil engineering = 125%) and long-period project (equal to or over 48 months construction = 133%) compared to general construction (98~116%) and short-period project (less than 48 months construction = 115%). The proportion of spending expenses was higher in the category of safety manager labor costs (25~52%), safety facility costs (22~40%), and personal protective equipment costs (10~25%). The analysis results of the study can be utilized in revising the standard expense appropriation method by reflecting the current usages of the occupational safety and health management expenses in the construction industry.

• Journal of Pharmaceutical Investigation
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• 제25권1호
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• pp.31-36
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• 1995

Solid dispersions and inclusion complex were prepared for the enhancement of solubility and dissolution rate of poorly water-soluble ibuprofen(IPF) as a model drug. Polyethylene glycol 4000(PEG4000) and polyvinylpyrrolidone(PVP) were used for the preparation of solid dispersion. $2-Hydroxypropyl-{\beta}-cyclodextrin(2-HP{\beta}CD)$ was also used for the preparation of inclusion complex. The solubility of IPF increased as the concentration of PEG4000, PVP and $2-HP{\beta}CD$ increased. Solubilization capacity of $2-HP{\beta}CD$ was increased about 10 times when compared to PEG 4000 and PVP. The dissolution rate of drug from solid dispersions and inclusion complex in the simulated gastric fluid was enhanced when compared to pure IPF and commercial $BR4^{\circledR}$ tablet as a result of improvement of solubility. In case of solid dispersions, dissolution rate of drug was proportional to polymer concentration in the formulation. The marked enhancement of dissolution rate of drug by inclusion complexation with $2-HP{\beta}CD$ was noted. However, dissolution rate of drug from solid dispersions and inclusion complex in the simulated intestinal fluid was not significant because IPF was readily soluble in that condition. From these findings, water-soluble polymers and cyclodextrin were useful to improve solubility and dissolution rate of poorly water-soluble drugs. However, easiness and reliability of preparation method, scale-up and cost of raw materials must be considered for the practical application of solid dispersion and inclusion complex in pharmaceutical industry.

• 한국지역지리학회지
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• 제18권4호
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• pp.400-413
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• 2012

본 연구는 지방첨단산업단지의 형성과정과 특성을 살펴보기 위해 오창과학단지를 사례로 입주한 기업체의 업종별, 종사자 수규모별 특성과 기업의 이전과정을 분석하였다. 분석 자료는 기업통계 자료와 기업체들을 대상으로 설문조사 내용이었으며 분석 결과는 다음과 같다. 첫째, 오창과학단지에 입지한 기업체들은 IT산업과 BT산업이 혼재되어 나타났다. 둘째, 오창과학단지 내에 입주한 기업들의 규모별 특성은 대기업보다는 중소규모의 기업체가 많았다. 그리고 입주한 기업들은 새로운 상품을 개발하고 마케팅을 하는 단계에 있으며, 핵심적인 기술이나 벤처 인증을 받은 혁신성이 높은 부품 소재 업체들이 많았다. 셋째 오창과학단지에 입주한 기업들은 수도권과 충청권에서 이주한 기업의 비율이 높았고 본사와 함께 입주한 비율이 70% 이상을 차지했다. 넷째 기업들은 생산품 유형과 기술의 보유 정도에 따라 크게 4가지 유형으로 분류되었다.

• 국제물리치료학회지
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• 제11권2호
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• pp.2052-2059
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• 2020

Background: Kinesiology taping (KT) is a method that helps immediately increase muscle activation, strength and joint stability by being attached to various skeletal muscles and structures of the body. Objectives: To investigate the effect of KT applied below the hyolaryngeal complex on the movement of the hyolaryngeal complex during swallowing in patients with dysphagia after stroke. Design: One-group, pre-post design. Methods: Twenty individuals with dysphagia after stroke participated in this study. KT was applied to the sternum and both clavicles from the hyolaryngeal complex. We analyzed the motion of the hyolaryngeal complex during swallowing with and placebo KT and KT using the Image-J software with videofluoroscopic swallowing study. In addition, a 0-to-10 numerical rating self-report scale was used to check the required effort and resistance felt during swallowing. Results: KT condition showed that the anterior and superior movement of the hyoid bone during swallowing was significantly lower than placebo KT (P<.05, all). Also, KT condition showed that the anterior and superior movement of the larynx during swallowing was significantly lower than placebo KT (P<.05, all). In result of statistical comparison between KT group and placebo KT group, the KT group showed significantly higher self-report scale score than the placebo KT group in terms of two category; the required effort and resistance felt (P<.05, all). Conclusion: This study demonstrated that KT applied below the hyolaryngeal complex inhibits the anterior and superior movement of hyoid bone and larynx during swallowing of patients with dysphagia after stroke.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2007년도 추계학술대회논문집
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• pp.1120-1124
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• 2007

Recently in the automotive brake industry brake squeal noise has become one of the top automotive quality warranty issues. The contact pressure is used to predict friction coupling in the brake squeal analysis. The formulation of friction coupling has performed by nonlinear static analysis prior to the complex eigenvalue analysis. This paper proposes a validation methodology of squeal analysis using modal testing and contact analysis and examines the effect of predicted contact pressure that leads to the discrepancy between unstable complex mode and squeal frequency. This studies compose a three step validation process : examining the modal characteristics of component and assembly loaded contact pressure using modal testing and FEM analysis and verifying the contact pressure distribution using nonlinear static analysis and experiment. Finally, the unstable modes from complex eigenvalue analysis and realistic squeal frequency from the noise dynamometer are investigated.

• 한국가스학회지
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• 제4권2호
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• pp.15-19
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• 2000

본 연구에서는 기존의 연구 개발된 다양한 확산모델의 비교 및 분석을 통하여 국내 석유화학시설에 적용하는 것이 적합하다고 판단되는 미국 EPA의 Industrial Source Complex(ISC)모델을 3차원 모사 대상으로 선정하여, 3차원 모사논리를 적용한 모사시스템을 개발하였다. 따라서 개발된 모사 시스템을 국내 화학산업시설에 적용할 경우, 정확한 사고피해 범위 예측과 더불어 화학산업시설의 비상조치계획 수립, 점화원 관리 등의 사고예방 및 사고피해의 최소화 측면에서도 많은 부분 기여할 수 있을 것이다.

• 농촌지도와개발
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• 제19권1호
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• pp.129-145
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• 2012

There are many positioning studies utilizing Analytic Hierarchy Process (AHP) in tourism industry. In this study, it was tried to develop new evaluation criteria for positioning and to discuss the importance of evaluation factors, as the development of tourist's spots was pursued in diversified ways. The purpose of this study was to allow the development of tourist spots more objectively and more efficiently utilizing Analytic Hierarchy Process ("AHP" hereunder) to appoint the best place for the tourism complex in Buyeo. According to AHP analysis procedures, 5 places near Baikje Cultural Block connecting with a ferry in Buyeo-gun were selected as candidates. To perform AHP analysis, evaluation criteria and a survey were used and then weight of evaluation criteria was induced. With the conditions on criteria, standard score of each criterion and candidate was calculated. By multiplying standard score and final weight and then summing up, the candidate place with the highest score shall be appointed as the most optimal place for Buyeo-gun Agricultural Tourism Complex.