• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.21 no.10
• /
• pp.1702-1711
• /
• 1997

A numerical study for the number of terms of a power series stress function and the effect of hybrid element size on stress analysis around a hole in loaded orthotropic composites is presented. The hybrid method coupling experimental and/or theoretical inputs and complex variable formulations involving conformal mappings and analytical continuity is used to calculate tangential stress on the boundary of the hole in uniaxially loaded, finite width glass epoxy tensile plate. The tests are done by rarying the number of terms, element size and nodal locations on the external boundary of the hybrid region. The numerical results indicate that the hybrid method is accurate and powerful in both experimental and numerical stress analysis.

• Journal of the Korean Chemical Society
• /
• v.51 no.4
• /
• pp.331-338
• /
• 2007

A rapid, simple and sensitive spectrophotometric method was developed for the determination of cobalt(II) using 2-hydroxy-3-methoxy benzaldehyde thiosemicarbazone (HMBATSC) as a analytical reagent. The metal ion in aqueous medium forms a brown coloured complex with HMBATSC at pH 6.0. The complex has two absorption maxima at 375 nm and 390 nm. At 375 nm, the reagent shows considerable absorbance, while at 390 nm the reagent does not shows appreciable absorbance. Hence, analytical studies were carried out at 390 nm. Beer's law is obeyed in the range of 0.059-2.357 μg ml-1 of Co(II). The molar absorptivity and Sandall's sensitivity of the method are 2.74×104 l mol-1 cm-1 and 0.0024 μg cm-2 respectively. The interference of various diverse ions has been studied. The complex has 1:2 [Co(II)- HMBATSC] stoichiometry. A method for the determination of cobalt(II) by second order derivative spectrophotometry has also been proposed. The proposed methods were applied for the determination of cobalt(II) in alloy steels, vitamin B12 and in some biological samples.

• YAKHAK HOEJI
• /
• v.57 no.3
• /
• pp.226-233
• /
• 2013

Although the dissolution test can serve as an effective tool for quality control and predictor of in vivo performance, there are a number of drugs with no established dissolution specification in Korean Pharmaceutical Codex (KPC). So, with each reference and test drugs, the dissolution test method and an analytical procedure by HPLC were developed and validated to establish dissolution specification for acebrophylline capsules and bromhexine hydrochloride tablets. The dissolution condition was determined based on the "Guidelines on Specifications of Dissolution tests for Oral dosage forms" of Ministry of Food and Drug Safety (MFDS). The analytical method of HPLC was validated in specificity, linearity, precision and accuracy. Final dissolution test was performed with commercially available samples of 3 lots to establish specification. In addition, no difference was observed by the inter-laboratory evaluation. Dissolution specifications and conditions will be used for revising the monograph of acebrophylline capsules and bromhexine hydrochloride tablets in next supplement of KPC.

• Analytical Science and Technology
• /
• v.6 no.3
• /
• pp.247-254
• /
• 1993

Strontium can not be determined by conventional dc polarography method since it is very difficult to be reduced at the drop mercury electrode(DME) in aqueous solution. However the analytical sensitivity was improved by adsorptive stripping voltammetry in which electro-reduction of ligand in a complex formed between strontium and o-cresolphthaleoxone was performed. Strontium could be determined in range of $5{\sim}30{\mu}g/L$ concentration. This method was affected by coexistent alkali earth metal ions. Consequently ion exchange separation is recommended to analyze strontium in samples.

• Analytical Science and Technology
• /
• v.21 no.3
• /
• pp.237-243
• /
• 2008

Nano core shell structures of $TiO_2$ particles coated on surface of ZnO nanoparticles were prepared by the polymerized complex and sol-gel method. The average particle size of ZnO by the polymerized complex method showed 100 nm and the average particle size of $TiO_2$ by the sol-gel method showed below 10 nm. The average particle size of $ZnO@TiO_2$ nano core shell struture represented about 150 nm. The agglomeration between the ZnO particles using the polymerized complex method was highly controlled by the uniform absorption of $TiO_2$ colloid on the spherical ZnO surfaces. The driving force of heterogeneous bonding between ZnO and $TiO_2$ was induced by the Coulomb force. The ZnO and $TiO_2$ particles electrified with + and - charges, respectively, resulted in strong bonding by the difference of iso-electric point (IEP) when they laid neutrality pH area, depending on the heterogeneous surface electron electrified by the different zeta potential on the pH values.

• Smart Structures and Systems
• /
• v.13 no.4
• /
• pp.587-614
• /
• 2014

In recent years the interest in online monitoring of lightweight structures with ultrasonic guided waves is steadily growing. Especially the aircraft industry is a driving force in the development of structural health monitoring (SHM) systems. In order to optimally design SHM systems powerful and efficient numerical simulation tools to predict the behaviour of ultrasonic elastic waves in thin-walled structures are required. It has been shown that in real industrial applications, such as airplane wings or fuselages, conventional linear and quadratic pure displacement finite elements commonly used to model ultrasonic elastic waves quickly reach their limits. The required mesh density, to obtain good quality solutions, results in enormous computational costs when solving the wave propagation problem in the time domain. To resolve this problem different possibilities are available. Analytical methods and higher order finite element method approaches (HO-FEM), like p-FEM, spectral elements, spectral analysis and isogeometric analysis, are among them. Although analytical approaches offer fast and accurate results, they are limited to rather simple geometries. On the other hand, the application of higher order finite element schemes is a computationally demanding task. The drawbacks of both methods can be circumvented if regions of complex geometry are modelled using a HO-FEM approach while the response of the remaining structure is computed utilizing an analytical approach. The objective of the paper is to present an efficient method to couple different HO-FEM schemes with an analytical description of an undisturbed region. Using this hybrid formulation the numerical effort can be drastically reduced. The functionality of the proposed scheme is demonstrated by studying the propagation of ultrasonic guided waves in plates, excited by a piezoelectric patch actuator. The actuator is modelled utilizing higher order coupled field finite elements, whereas the homogenous, isotropic plate is described analytically. The results of this "semi-analytical" approach highlight the opportunities to reduce the numerical effort if closed-form solutions are partially available.

• Analytical Science and Technology
• /
• v.27 no.3
• /
• pp.121-139
• /
• 2014

In this review, we will discuss aptamer technologies including in vitro selection, signal transduction mechanisms, and designing aptamers and aptazyme for label-free biosensors and catalysts. Dye-displacement, a typical label-less method, is described here which allows avoiding relatively complex labeling steps and extending this application to any aptamers without specific conformational changes, in a more simple, sensitive and cost effective way. We will also describe most recent and advanced technologies of signaling aptamer and aptazyme for the various analytical and clinical applications. Quantum dot biosensor (QDB) is explained in detail covering designing and adaptations for multiplexed protein detection. Application to aptamer array utilizing self-assembled signaling aptamer DNA tile and the novel methods that can directly select smart aptamer or aptazyme experimentally and computationally will also be finally discussed, respectively.

• 유공압시스템학회:학술대회논문집
• /
• 2010.06a
• /
• pp.39-43
• /
• 2010

It is hard and complex to analytically derive a volumetric displacement formula of a gerotor hydraulic motor because geometric shape of its rotors is complicate. An analytical method about the volumetric displacement is proposed in this work, which is relatively easy and based upon two physical concepts. The first one is energy conservation between hydraulic input energy of the motor and mechanical output energy. The second concept is torque equilibrium with respect to inner and outer rotors. The proposed formula about the volumetric displacement is verified by comparing an analytical displacement and a numerical displacement for an example specification of the motor. The numerical displacement is calculated through a kind of CAD technology. The analytical formula can be utilized in analysis and design of hydraulic gerotor motors.

• Structural Engineering and Mechanics
• /
• v.40 no.2
• /
• pp.279-295
• /
• 2011

A solution of space curved bars with generalized Winkler soil found by means of Transfer Matrix Method is presented. Distributed, concentrated loads and imposed strains are applied to the beam as well as rigid or elastic boundaries are considered at the ends. The proposed approach gives the analytical and numerical exact solution for circular beams and rings, loaded in the plane or perpendicular to it. A well-approximated solution can be found for general space curved bars with complex geometry. Elastic foundation is characterized by six parameters of stiffness in different directions: three for rectilinear springs and three for rotational springs. The beam has axial, shear, bending and torsional stiffness. Numerical examples are given in order to solve practical cases of straight and curved foundations. The presented method can be applied to a wide range of problems, including the study of tanks, shells and complex foundation systems. The particular case of box girder distortion can also be studied through the beam on elastic foundation (BEF) analogy.

• Steel and Composite Structures
• /
• v.44 no.1
• /
• pp.91-104
• /
• 2022

The purpose of the present work is to study the parametric nonlinear vibration behavior of three layered symmetric laminated plate. In the analytical formulation; both normal and shear deformations are considered in the core layer by means of the refined higher-order zig-zag theory. Harmonic balance method in conjunction with Galerkin procedure is adopted for simply supported laminate plate, to obtain its natural and damping properties. For these aims, a set of complex amplitude equations governed by complex parameters are written accounting for the geometric nonlinearity and viscoelastic damping factor. The frequency response curves are presented and discussed by varying the material and geometric properties of the core layer.