• 제목/요약/키워드: complex analytical method

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Study on analytical method of residual benzimidazole anthelmintics in meat by LC/MS (LC/MS를 이용한 식육중 잔류 벤지미다졸계 구충제 분석법 연구)

  • Choi Eun-Young;Seo Heyng-Seok;Baek Kui-Jeong;Hur Boo-Hong;Seo Lee-Won;Joung Dong-Suk
    • Korean Journal of Veterinary Service
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    • v.28 no.1
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    • pp.81-89
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    • 2005
  • Recently, mass spectrometry coupled with liquid chromatography (LC/MS) has been a preferred technique for determination of organic compounds in complex matrixes. LC/MS provides a high degree sensitivity and specificity of the compounds of interest. The purpose of this study was to confirm analytical method of residual 6 benzimidazoles (thiabendazole, oxfendazole, mebendazole, albendazole, flubendazole and fenbendazole) in meat by LC/MS. Benzimidazoles were analyzed by LC/MS on XTerra $C_{18}$ column with 0.01% trifluoroacetic acid-acetonitrile (TFA) in a gradient mode as mobile phase, and that were identified by electrospray ionization with selected ion recording mode at 150-350 amu mass range. Residual benzimidazoles were extracted from tissue with ethylacetate, and elute benzimidazoles with $50\%$ acetonitrile. In the LC/MS analysis of benzimidazoles, signal to noise ratio was showed relatively high in the positive mode and special ion in the quality analysis was determined via $[M+H]^+$ and Fragment ions. A spectrum of benzimidazoles was showed from all 6 benzimidazoles

The Study on the Development of Automatic Rebar Placement System Applying Selection Method of Optimum Reinforcing Bar Group on Shear Wall (최적배근그룹 선정방법을 적용한 전단벽체의 자동배근 시스템 개발에 관한 연구)

  • Cho, Young-Sang;Kim, Dong-Eun;Jin, Hyun-Ah;Jang, Hyun-Suk
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.19 no.1
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    • pp.81-89
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    • 2015
  • This study takes shear wall of reinforced concrete structure as study object, and the purpose of this study is to suggest structure BIM based on automatic reinforcing bar placement system applying set-based design through the most optimum reinforcing bar placement group that was selected by applying AHP (analytical hierarchy process) method from design step. For this, the most optimum reinforcing bar placement group was selected by pairwise comparison analysis on complex standard of multiple alternatives. And shear wall automatic reinforcing bar placement system has been developed, which can automatically generate members and arrange reinforcing bar by structure design algorithm and using open API (application programming interface) provided by a BIM software vendor. As a result, the most optimum reinforcing bar placement group of the highest weight, ALT1, was selected and was generated using Tekla Structure program.

Development of a New Method for Total Isocyanate Determination Using the Reagent 9-Anthracenylmethyl 1-Piperazinecarboxylate(PAC):Part 1 - The reaction condition and stability (9-Anthracenylmethyl 1-Piperazinecarboxylate(PAC)을 이용한 공기중 총이소시아네이트 분석방법 개발:제1부 반응조건 및 안전성)

  • Roh, Young-Man;Streicher, Robert P.
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.9 no.2
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    • pp.167-176
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    • 1999
  • A new analytical procedure for the measurement of monomeric isocyanates and total isocyanate group in workplaces has been investigated. The method described herd involves derivatization of the isocyanate sample upon collection with the reagent 9-anthracenylmethyl 1-piperazinecarboxylate (PAC). Laboratory investigations have demonstrated that excess PAC reagent can be satisfactorily removed from PAC-derivatized monomeric isocyanates-a requirement for the success f the analytical procedure. After removal of excess PAC reagent, the PAC derivatives of butyl isocyanate, phenyl isocyanate, HDI, MDI, and TDI were reacted with sodium thiomethoxide to convert them all to 9-anthracenylmethyl methyl sulfide (AMMS). Total isocyanate group was determined by HPLC analysis and quantification of the single AMMS peak. This circumvents many of the disadvantages associated with current HPLC methods. There were no longer problems associated with quantifying late-eluting peaks and analysis times were very short. A single detector was used for quantification because a standard of the analyte existed and the retention time could be determined. Because all species were converted to a single analyte, the problem of variability of response factors among different species was averted. Finally, there were no complex chromatograms to interpret. Monomers of other individual species were measured by analysis of the sample before the individual species were converted to AMMS. The favorable performance of PAC warrants its further study as a reagent for the determination of total isocyanate group in air.

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Curvature-based analysis of concrete beams reinforced with steel bars and fibres

  • Kaklauskas, Gintaris;Sokolov, Aleksandr;Shakeri, Ashkan;Ng, Pui-Lam;Barros, Joaquim A.O.
    • Structural Engineering and Mechanics
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    • v.81 no.3
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    • pp.349-365
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    • 2022
  • Steel fibre-reinforced concrete (SFRC) is an emerging class of composite for construction. However, a reliable method to assess the flexural behaviour of SFRC structural member is in lack. An analytical technique is proposed for determining the moment-curvature response of concrete beams reinforced with steel fibres and longitudinal bars (R/SFRC members). The behaviour of the tensile zone of such members is highly complex due to the interaction between the residual (tension softening) stresses of SFRC and the tension stiffening stresses. The current study suggests a transparent and mechanically sound method to combine these two stress concepts. Tension stiffening is modelled by the reinforcement-related approach assuming that the corresponding stresses act in the area of tensile reinforcement. The effect is quantified based on the analogy between the R/SFRC member and the equivalent RC member having identical geometry and materials except fibres. It is assumed that the resultant tension stiffening force for the R/SFRC member can be calculated as for the equivalent RC member providing that the reinforcement strain in the cracked section of these members is the same. The resultant tension stiffening force can be defined from the moment-curvature relation of the equivalent RC member using an inverse technique. The residual stress is calculated using an existing model that eliminates the need for dedicated mechanical testing. The proposed analytical technique was validated against test data of R/SFRC beams and slabs.

Damping of a taut cable with two attached high damping rubber dampers

  • Cu, Viet Hung;Han, Bing;Wang, Fang
    • Structural Engineering and Mechanics
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    • v.55 no.6
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    • pp.1261-1278
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    • 2015
  • Due to their low intrinsic damping, stay cables in cable-stayed bridges have often exhibited unanticipated and excessive vibrations which result in increasing maintenance frequency and disruption to normal operations of the entire bridges. Mitigation of undesired cable vibration can be achieved by attaching an external damping device near the anchorage. High Damping Rubber (HDR) dampers have many advantages such as compact size, better aesthetics, easy maintenance, temperature stability, and cost benefits; therefore, they have been widely used to increase cable damping. Although a single damper has been shown to reduce cable vibrations, it is not the most effective method due to geometric constraints. This paper proposes the use of two HDR dampers to improve effectiveness and robustness in suppressing cable vibration. Oscillation parameters of the cable-dampers system were investigated in detail by modeling the stay cable as a taut string and each HDR damper as complex-valued impedance and by using an analytical formulation of the complex eigenvalue problem. The problem of two HDR dampers arbitrarily located along a cable is solved and the solution is discussed. Asymptotic formulas to calculate the damping ratios of the cable with two HDR dampers installed near the anchorage(s) are proposed and compared with the exact solutions. Further, a design example is presented in order to justify the methodology. The results of this study show that when the two HDR dampers are installed close to each other on the same end of the cable, some interaction between the dampers leads to reduced damping ratio. When the dampers are on the opposite ends of the cable, they are effective in increasing damping ratio and can provide better vibration reduction to multiple modes.

Effects of Coffee Shop Choice Attributes and Type of Coffee Shop on Customer Satisfaction : Using Fuzzy Set Qualitative Comparative Analysis(fsQCA) (커피전문점 선택 속성과 점포유형의 결합 관계가 만족도에 미치는 영향 : 퍼지셋 질적비교분석(fsQCA)을 중심으로)

  • Han, Young-Wi;Lee, Yong-Ki;Ahn, Sung-Man
    • The Korean Journal of Franchise Management
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    • v.8 no.1
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    • pp.31-41
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    • 2017
  • Purpose - As the domestic coffee market is rapidly growing and competition is intensifying, coffee shops need to establish a marketing strategy that grasps the needs and desires of consumers in order to secure a competitive advantage in terms of survival. From this point of view, this study suggests what choice attributes consumers consider when visiting coffee shops, and analyzes the effect of customer choice attributes on franchise and private coffee shops using fsQCA. Research design, data, and methodology - In the present study, we tried to understand the effect of the combination of choice attribute on satisfaction by the type of coffee shop based on the complex system theory, while studying the existing coffee shop choice attribute focuses on the causal relationship. FsQCA is a complementary analytical method between quantitative and qualitative research, and is a method for effectively analyzing the complex combination of causal variables. Result - The results of the study are as follows. First, cleanliness was found to be the most important factor in determining coffee quality, which is the most important factor affecting customer satisfaction. Second, customers who prefer franchise coffee shops seem to be most concerned about atmosphere, menu, cleanliness and price. On the other hand, customers who prefer private coffee shops consider image the most important. Conclusions - The implications of this study are as follows. Overall, coffee shops should manage cleanliness basically regardless of the type of store, but they should manage the choice attributes differently depending on the type of coffee shop. Franchise coffee shops will be able to increase the level of store satisfaction by systematically managing the store atmosphere, menu, cleanliness, and price according to the manual using the advantages of the franchise system. On the other hand, unlike the franchise coffee shops, private coffee shops can operate autonomous stores, so customers can use various marketing mixes to enhance their store image.

On the Evaluation of Physical Distribution Service in Ports (항만물류서비스의 평가에 관하여)

    • Journal of Korean Port Research
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    • v.10 no.2
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    • pp.17-29
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    • 1996
  • It is required to consider pricing and non-pricing factors and external economy in order to achieve the objects of physical distribution system in a port. Recently, among the three factors, much attention has been paid to non-pricing factor in the system. Although physical distribution service in a port(PDSP)has been frequently mentioned in documents and literature related to port and shipping studies, few study on it has not been systematically and scientifically made due to the following problems; $\circ$ there are not proper criteria to evaluate level and quality of PDSP and as a result it is difficult to set up a unified standard for doing so. $\circ$ algorithms to evaluate problems with complex and ambiguous attributes and multiple levels in PDSP are not available. This thesis aims to establish a paradigm to evaluate PDSP and to abvance existing decision making methods to deal with complex and ambiguous problems in PDSP. To tackle the first purpose, extensive and thorough literature survey was carried out on general physical distribution service, which is a corner stone to handle PDSp. In addition, through interviews and questionnaire to the expert, it have extracted 82 factors of physical distribution service in a port. They have been classified into 6 groups by KJ method and each group defined by the expert's advice as follows; a. Potentiality b. Exactness c. safety d. Speediness e. Convenience f. Linkage Prior to the service evaluation, many kinds of its attributes must be identified on the basis of rational decision owing to complexity and ambiguity inherent in PDSP. An analytical hierarchy process (AHP) is a method to evaluate them but it is not applicable to PDSP that have property of non-additivity and overlapped attributes. Therefore, probablility measure can not be used to evaluate PDSP but fuzzy measure is required. Hierarchical fuzzy integral method, which is merged AHP with fuzzy measure, is also not effective method to evaluate attributes because it has vary complicated way to calculate fuzzy measure identification coefficient of attributes. A new evaluation algorithm has been introduced to solve problems with multi-attribute and multi-level hierarchy, which is called hierarchy fuzzy process(HFP).Analysis on ambiguous aspects of PDSP under study which is not easy to be defined is prerequisite to evaluate it. HFP is different from algorithm existed in that it clarified the relationship between fuzzy measure and probability measure adopted in AHP and that it directly calculates the family of fuzzy measure from overlapping coefficient and probability measure to treat and evaluate ambiguous and complex aspects of PDSP. A new evaluation algorithm HFP was applied to evaluate level of physical distribution service in the biggest twenty container port in the world. The ranks of the ports are as follows; 1. Rotterdam Port, 2. Hamburg Port, 3. Singapore Port, 4. Seattle Port, 5. Yokohama Port, 6. Long beach Port, 7. Oakland Port, 8. Tokyo Port, 9. Hongkong Port, 10. Kobe Port, 11. Los Angeles Port, 12. New york Port, 13. Antwerp Port, 14. Felixstowe Port, 15. Bremerhaven Port, 16. Le'Havre Port, 17. Kaoshung Port, 18. Killung Port, 19. Bangkok Port, 20. Pusan Port

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Size Effects in the Failure of Specially Orthotropic Sandwich Slab Bridges (치수효과를 고려한 특별직교이방성 샌드위치 슬래브교량의 파괴강도해석)

  • Han, Bong Koo;Lee, Yong Ho
    • Journal of Korean Society of Steel Construction
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    • v.16 no.3 s.70
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    • pp.333-344
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    • 2004
  • In civil engineering applications, the establishment of standards and procedures for analysis, design, fabrication, construction, and quality control are essential in facilitating the economic and efficient use of composite materials. Many bridge systems, including girders. cross beams, and concrete decks, function as specially orthotropic plates. in general, the analytical solution for such complex systems is very difficult to achieve. Thus, the finite difference method is used for the analysis of the problem. The rate of tensile strength reduction due to increased size is considered. Strength reduction is necessary to ensure the safe design of building structures. This paper suggests the use of a strength-failure analysis procedure using the reduced tensile strength. A numerical study is conducted for different cases. The Tasi-Wu failure criterion for stress space is also used.

Estimation of Interaction Effects among Nucleotide Sequence Variants in Animal Genomes

  • Lee, Chaeyoung;Kim, Younyoung
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.1
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    • pp.124-130
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    • 2009
  • Estimating genetic interaction effects in animal genomics would be one of the most challenging studies because the phenotypic variation for economically important traits might be largely explained by interaction effects among multiple nucleotide sequence variants under various environmental exposures. Genetic improvement of economic animals would be expected by understanding multi-locus genetic interaction effects associated with economic traits. Most analyses in animal breeding and genetics, however, have excluded the possibility of genetic interaction effects in their analytical models. This review discusses a historical estimation of the genetic interaction and difficulties in analyzing the interaction effects. Furthermore, two recently developed methods for assessing genetic interactions are introduced to animal genomics. One is the restricted partition method, as a nonparametric grouping-based approach, that iteratively utilizes grouping of genotypes with the smallest difference into a new group, and the other is the Bayesian method that draws inferences about the genetic interaction effects based on their marginal posterior distributions and attains the marginalization of the joint posterior distribution through Gibbs sampling as a Markov chain Monte Carlo. Further developing appropriate and efficient methods for assessing genetic interactions would be urgent to achieve accurate understanding of genetic architecture for complex traits of economic animals.

Nonstationary Response Analysis of Offshore Guyed Tower for Strong Earthquakes (비정상과정의 강한 지진에 대한 해양 가이드 타워의 동력학적 응답해석)

  • 류정선
    • Computational Structural Engineering
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    • v.5 no.3
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    • pp.127-137
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    • 1992
  • A method for nonstationary response analysis of an offshore guyed tower subjected to earthquake loading is presented. The nonstationarity of the earthquake excitation is modeled by imposing a time varying envelope function onto a stationary random model. By taking the envelope function and the auto-correlation function of ground acceleration in terms of complex exponential functions of time, an analytical procedure is developed for computing time varying variances of the tower response. Example analysis indicates that the maximum responses estimated by considering nonstationary effect properly are significantly less than those obtained by the conventional frequency domain analysis method based upon the stationary assumption.

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