• Natural Product Sciences
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• v.6 no.2
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• pp.70-72
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• 2000

The effects of coptisine on monoamine oxidase (EC 1.4.3.4; MAO) activity in mouse brain were investigated. Coptisine showed an inhibitory effect on MAO activity with a concentration-dependent manner. Coptisine exhibited 51.0% inhibition of MAO activity at $9\;{\mu}M$. The $IC_{50}$ value of coptisine was $8.7\;{\mu}M$. Coptisine inhibited MAO activity competitively with kynuramine as a substrate. The $K_i$ value of coptisine was $4.1\;{\mu}M$. These results indicate that coptisine functions to regulate the catecholamine content at biologically active sites.

• Communications for Statistical Applications and Methods
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• v.23 no.5
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• pp.363-383
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• 2016

The Weibull family of lifetime distributions play a fundamental role in reliability engineering and life testing problems. This paper investigates the potential usefulness of transmuted new generalized Weibull (TNGW) distribution for modeling lifetime data. This distribution is an important competitive model that contains twenty-three lifetime distributions as special cases. We can obtain the TNGW distribution using the quadratic rank transmutation map (QRTM) technique. We derive the analytical shapes of the density and hazard functions for graphical illustrations. In addition, we explore some mathematical properties of the TNGW model including expressions for the quantile function, moments, entropies, mean deviation, Bonferroni and Lorenz curves and the moments of order statistics. The method of maximum likelihood is used to estimate the model parameters. Finally the applicability of the TNGW model is presented using nicotine in cigarettes data for illustration.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2005.05a
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• pp.207-214
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• 2005

Productivity and quality stability are very important competitive factors in PCB manufacturing lines that process the multiple types of products with the mixed process flows under frequent order information changes. MES is an appropriate IT solution to solve these problems in the medium-sized PCB manufacturing company. This paper introduces the MES development and its effects for a medium-sized PCB manufacturing company. The main functions of an implemented MES are delivery simulation, production scheduling, and production process monitoring. Productivity are improved up to $10{\sim}20%$ and manufacturing lead times per order are shortened up to 2 days according to the manufacturing scenarios.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.7
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• pp.1199-1204
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• 2007

In a cost based pool market, the generation capacity can be used as strategic bids by generation companies (Gencos) with the cost functions open to the market. Competition using strategic capacities is modeled by Cournot and Perfect Competiton (PC) model, and transformed into two by two payoff matrix game with Gencos' decision variables of Cournot and PC model. The payoff matrices vary when capacity payments are given to Gencos in accordance with their capacity bids. Nash Equilibrium (NE) in the matrices also moves with capacity price changes. In order to maximize social welfare of the market, NE should locate in a certain position of the payoff matrices, which corresponds to a PC NE. A concept of a critical capacity price is proposed and calculated in this paper that is defined as a minimum capacity price leading to PC NE. The critical capacity price is verified to work as a tool for suppressing a strategic capacity withholding in simulations of a test system.

• Proceedings of the KIEE Conference
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• 2006.10c
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• pp.494-496
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• 2006

There are several types of communication method which is used for the supply of electric power stably. But the communication methods used in KEPCO have weak points in the viewpoint of economy, technology and management. The Satellite communication systems have competitive rover in price and technology for national wide utility owing to its wide area coverage and stability. For better practical use of satellite communication in power industry, we developed the portable satellite communication terminal. This paper presents various functions and composition of the portable terminal for rower industry.

• Journal of the Korea Safety Management & Science
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• v.3 no.3
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• pp.165-174
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• 2001

Internet is a global network and it produces many terminologies involved in Electronic Commerce. Among many terms people very much talked about Cyber Shopping Mall. Under situation customers and sellers paid attention to Cyber Shopping Mall which is beyond time and space. This study deals with two subjects to enlarge the competitive power of Mall & Malls which is integration of multiple Cyber Shopping Mall. First subject is constructing the Automated Mall Wizard which is efficiently and effectively building Cyber Shopping Mall Site. And second subject is to differentiate from other shopping malls. Automated Mall Wizard is composed of three stages which are decomposed into several descriptive steps. And descriptive steps takes form of independent module, so it is considered to maximize Cyber Shopping Mall differentiation. Additional functions are making the goods category, related goods to be simultaneously ordered, price comparison with other sites within the Mall & Malls, best seller goods, store advertisement, substitutive goods, and mileage policy. As a result of that, we can respect SuperMall is better than other Mall & Mall as to diversity and flexibility of constructed Cyber Shopping Mall.

• Journal of the Korea Safety Management & Science
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• v.10 no.3
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• pp.127-135
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• 2008

In this study, we offered a way that is to make warehouse industry clustered in Incheon port for getting competitive and high end value added activities like advanced port logistics center considering trend that is changing functions of port and importance of port-hinterland. For this, we studied the existing research about port cluster, the present condition of warehouse industry in Incheon port and importance of value-added logistics activities. Also, we offered needs to build a high value-added and integrated logistics center by examples of advanced port logistics center in Singapore, Netherlands(Rotterdam) and Hongkong. We get the questionnaires for gathering ideas of port logistics industry about to set integrated logistics centers by strategy we offered that is making warehouse logistics clustered.

• 제어로봇시스템학회:학술대회논문집
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• 1993.10a
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• pp.724-730
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• 1993

Most of clustering methods usually employ the center of a cluster to assign the input data into a cluster. When the shape of a cluster could not be easily represented by the center of cluster, however, it is difficult to assign input data into a proper cluster using previous methods. In this paper, to overcome such a difficulty, a cluster is to be represented as a collection of several subclusters. And membership functions are used to represent how much input data belong to subclusters. Then the position of each subcluster is adoptively corrected by use of a competitive learning neural network. To show the validity of the proposed method, a numerical example is illustrated, where FMMC(Fuzzy Min-Max Clustering) algorithm is compared with the proposed method.

• Korean Journal of Computational Design and Engineering
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• v.19 no.2
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• pp.103-110
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• 2014

Engineering changes are indispensable engineering and management activities for manufactures to develop competitive products and to maintain consistency of its product data. Analysis of engineering changes provides a core functionality to support decision makings for engineering change management. This study aims to develop a method for analysis of engineering changes based on On-Line Analytical Processing (OLAP), a proven database analysis technology that has been applied to various business areas. This approach automates data processing for engineering change analysis from product databases that follow an international standard for product data management (PDM), and enables analysts to analyze various aspects of engineering changes with its OLAP operations. The study consists of modeling a standard PDM database and a multidimensional data model for engineering change analysis, implementing the standard and multidimensional models with PDM and data cube systems and applying the implemented data cube to core functions of engineering change management, the evaluation and propagation of engineering changes.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1997.04a
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• pp.342-346
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• 1997

In the recent competitive market situation, the product development lead-time plays a significant role for the success of a manufacting company. One of the most important efforts required is reducing the design lead-time by managing all the necessary technical information related to the design process. In this paper,the data model for an engineering data management system for machine tools is described by applying object-oriented modeling technique. The design objects and their structure are defined regarding the functions such as version control, configuration management, and technical document management, and are implemented using an object-relational database management system. The suggested model takes into special account the characteristics of machining centers.