• 제목/요약/키워드: comparison of efficacy

검색결과 923건 처리시간 0.033초

The Effect of Postural Balance and Fall Efficacy on Bilateral Visual Feedback Training with Visual Targets in Stroke Patients

  • No, Seung-Min;Hwang, Yoon-Tae;Son, Sung-Min
    • The Journal of Korean Physical Therapy
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    • 제34권2호
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    • pp.57-62
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    • 2022
  • Purpose: The purpose of this study was to determine the effects of bilateral visual feedback training with visual targets on the postural balance and fall efficacy of stroke patients with hemiparesis. Methods: A total of 24 stroke patients with hemiparesis were randomly assigned to either a bilateral visual feedback training (BVFT, n=8) group, unilateral visual feedback training (UVFT, n=8) group, or a control group (n=8). The BVFT and UVFT groups performed weight-bearing training on the bilateral (less-affected and affected side) or unilateral side (affected side) with visual feedback using visual targets. The control group performed squat training without visual feedback using visual targets. The training program was conducted in the form of 3 sets a day, 3 times a week, for 4 weeks. The participants were evaluated using the Berg balance scale (BBS), lateral reaching test (LRT), timed up and go test (TUG), and the activities-specific balance confidence scale (ABC). Results: In the intra-group comparison after the intervention, the BVFT group showed a significant difference in the BBS, TUG, affected and less-affected side LRT, and ABC (p<0.05). The UVFT group showed a significant difference in the BBS and ABC (p<0.05). In the inter-group comparison after the intervention, the BVFT group showed significant improvements in their BBS, affected side LRT, and TUG, when compared to the control group (p<0.05). Conclusion: These findings show that bilateral visual feedback training with visual targets during bilateral weight-bearing exercises can improve the postural balance function in stroke patients.

웹과 도서관 시스템에서 이용자 정보탐색 비교연구 (A Comparison of web Searching and Library System Searching: Perceived Difficulty, Self-Efficacy, and Effort)

  • 이수영
    • 정보관리학회지
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    • 제24권2호
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    • pp.29-44
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    • 2007
  • 본 연구는 왜 이용자들이 정보탐색에 많은 노력을 기울이지 않는가를 알아보기 위하여 교육심리학분야에서 개발된 정신적 노력에 관한 개념을 웹 검색엔진과 도서관시스템 정보탐색행위에 적용하여 보았다. 실험실 환경에서 학부학생 총 15명을 대상으로 탐색실험을 실시하여, 탐색전 설문조사, 탐색후 설문조사, 탐색후 인터뷰, 생각 소리내어 말하기(think-aloud), 로그데이터를 통하여 데이터를 수집하였다. 연구결과, 이용자들은 웹 검색엔진을 도서관시스템에 비하여 휠씬 쉽다고 인지하며 스스로 탐색에 대한 높은 자신감을 가지고 있었다. 이러한 이용자성향은 이용자들이 웹 탐색에 도서관 탐색때보다 더 적은 노력을 기기는 것과 깊은 연관성을 가지고 있는 것으로 나타났다. 이용자들의 정신적 노력에 관한 개념은 결과적으로 이용자들의 정보탐색 행위와 경험을 설명하는데 매우 유용한 것으로 밝혀졌다.

A Randomized Comparative Study of Unani Formulations in Abnormal Uterine Bleeding due to Endometrial Hyperplasia

  • Abothu Suhasini;Wasia Naveed;Arshiya sultana;Shahzadi Sultana
    • 셀메드
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    • 제13권14호
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    • pp.19.1-19.16
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    • 2023
  • Objectives: To compare the efficacy of polyherbal Unani formulations in heavy menstrual bleeding due to endometrial hyperplasia. Methodology: A prospective, randomized comparative trial was conducted at Govt. Nizamia Tibbi College. Group A (n=20) received Itrifal Aftimoon 5g orally BID from menstruation day 3 to day 21 plus suprapubic Marham Dakhilyun application and per vaginally Marham Dakhilyun (5g) and Roghan Gul (10ml) application from menstruation day 5 to day 14. Group B (n=20) received Gulnar Farsi (2g), Phitakri Biryan (0.25g), Dammul Aqwain (0.25g), and Geru (2g), 2.5g powder orally BID, menstruation day 3 for 20 days plus Douche Bargh Sambhalu then Ḥamūl of Safuf Mazu (2g), Kalijiri (2g) and Roghan Gul (10ml) from menstruation day 3 to day 12 for 3 consecutive cycles. The primary outcome was pelvic ultrasound findings of endometrial thickness. The secondary outcome measures were improvement in haemoglobin percentage, change in menstrual flow and menstrual pattern. The level of significance was 5%. Results and conclusion: The intragroup comparison showed that the mean endometrial thickness at baseline and after treatment in groups A and B was extremely significantly different (P<0.0001). The intragroup comparison showed the mean haemoglobin percent at baseline and after treatment in group, A was significantly different (P<0.0001). After treatment, 50% and 60% of participants had normal duration and menstrual blood loss after treatment from baseline in Groups A and B respectively. However, further, phase II and III randomized standard controlled trials in larger samples are recommended to assess the efficacy of these group medicines.

대학원에서의 영재교육 전공 여부에 따른 영재교사의 전문성 인식 및 교수효능감 비교 (Comparison between the Recognition of Professionalism and Teaching Efficacy of the Gifted Education Teacher by Majoring in Education for the Gifted from the Graduate School of Education)

  • 정진철;유미현
    • 영재교육연구
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    • 제23권5호
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    • pp.751-769
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    • 2013
  • 본 연구의 목적은 대학원에서의 영재교육 전공 여부에 따른 영재교사의 전문성 인식 및 교수 효능감에는 어떠한 차이가 있는지 비교하는 것이다. 본 연구 대상은 교육대학원 영재교육 전공자 44명과 영재교육을 전공하지 않은 초등학교 영재교사 56명이다. 본 연구에서 얻어진 결론은 다음과 같다. 첫째, 영재교육 전공자의 교과지식, 교수전략, 영재아 이해, 개인효능감과 결과기대감에서 영재교육 미전공자에 비해 통계적으로 유의미하게 높은 것으로 나타났다(p<.05). 대학원에서의 영재교육 전공은 영재교사로서의 전문성 인식을 높여주고, 교수효능감도 향상됨을 알 수 있다. 둘째, 영재교육 전공 여부 및 성별에 따른 이원변량분석 결과, 교과지식, 영재아 이해, 개인효능감에서 상호작용 효과가 나타났으며 여성이 남성보다 영재교육 전공 여부에 따른 전문성 인식과 교수효능감에 더 크게 영향을 받는 것으로 분석되었다. 영재교육 전공 여부와 영재지도 경력에 따라 분석한 결과, 교수전략과 개인효능감에서 유의미한 상호작용 효과가 나타났다(p<.05). 여교사와 영재지도 경력이 짧은 영재교사는 영재교육 전공 여부에 따라 남교사와 영재지도 경력이 오래된 교사에 비해 대학원에서의 영재교육 전공이 전문성 인식과 교수효능감 향상에 도움이 된다고 할 수 있다. 셋째, 전문성 인식과 교수효능감의 관계를 분석한 결과, 전문성 인식과 교수효능감의 모든 하위 영역에서 유의미한 정적 상관관계를 갖고 있는 것으로 나타났다(p<.05). 다중회귀분석 결과 교과지식과 교수전략이 개인효능감에 유의미한 영향을 미치는 것으로 나타났다(p<.05). 이로써 대학원에서의 영재교육 전공은 영재교사의 교과지식과 교수전략의 전문성 신장에 크게 영향을 미칠 수 있으며 나아가 교수효능감에도 긍정적인 영향을 미친다고 할 수 있다.

승기조위탕이 비만 유도 백서의 혈청성분 및 조직화학적 변화에 미치는 영향 (The Effects of Seunggijoui-tang on Body Weight, Biochemical and Histological Changes of Rats fed High Diet)

  • 박원경;김은하;변성희;박종현
    • 동의생리병리학회지
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    • 제17권1호
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    • pp.105-112
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    • 2003
  • This experimental study was designed to investigate the effects of Seunggijoui-tang on the weight of obese rats induced by high fat diet. A series of experiments have been conducted in order to measure the effects of above the body weight, serum and fat cell. The measurements have been performed on; (1) the increasing amount of body weight; (2) the quantity of total cholesterol, triglyceride, free fatty acid, total lipid, phospholipid, HDL-cholesterol and LDL-cholesterol in serum; (3) the size of the epididymal fat cell and the fat drops area in hepatic lobule. In the SG I (Group fed high fat diet and administered 42.5mg/100g extract of Seunggijoui-tang during 8 weeks), the weight decreased significantly throughout the whole research period. In the SG I & SG II (Group fed high fat diet and administered 85mg/100g extract of Seunggijoui-tang during 8 weeks), the serum total cholesterol, triglyceride, total lipid, phospholipid, LDL-cholesterol decreased significantly in comparison with control group. In the SG I, the serum free fatty acid decreased significantly in comparison with control group. In the SG I & SG II, the serum HDL-cholesterol decreased in comparison with control group, but this result showed no efficacy. In the SG I, the epididymal fat cell decreased significantly in comparison with control group. In the SG II, the fat drops area in hepatic lobule of rats decreased significantly in comparison with control group. Based on the above result, it is assumed that the clinical application of Seunggijoui-tang can help the treatment of obesity.

트랄로키누맙과 두필루맙의 매칭 조정 간접 비교 (Matching-adjusted Indirect Comparison (MAIC) of Tralokinumab Versus Dupilumab for the Treatment of Moderate to Severe Adult Atopic Dermatitis)

  • 김태경;신근수;김효진;김유진;최이정;이동훈
    • 한국임상약학회지
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    • 제33권3호
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    • pp.178-185
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    • 2023
  • Objective: Atopic dermatitis (AD) is a chronic, recurrent inflammatory skin disease. Both tralokinumab and dupilumab have been recommended in the European Guideline for the treatment of adult patients with severe AD. In Korea, dupilumab has been approved for patients with moderate to severe AD, and reimbursed for those with severe AD. Since there is no clinical trial directly comparing tralokinumab and dupilumab, we conducted indirect comparison to assess the clinical usefulness in patients with AD. Methods: We selected clinical trials for indirect comparison through a systematic literature review. Individual patient data were available for the tralokinumab clinical trial, and aggregated data were available for the dupilumab clinical trial. Therefore, we employed the Matching-Adjusted Indirect Comparison (MAIC) method. The treatment efficacy was assessed based on whether patients achieved a 75% reduction on the Eczema Area and Severity Index (EASI 75) after drug administration. Results: The difference in the proportion of patients achieving EASI 75 between tralokinumab and dupilumab was 4.7% (95% CI: -7.9 to 17.3). Considering the non-inferiority margin for the EASI 75 achievement rate is -10%, tralokinumab is deemed non-inferior to dupilumab as the lower bound of the CI for the difference in the EASI 75 achievement rate between tralokinumab and dupilumab was within -10%. Conclusion: We conducted a MAIC analysis comparing tralokinumab and dupilumab based on EASI 75 achievement. The findings of this study show that tralokinumab is non-inferior to dupilumab and can be implemented in Korean clinical settings with a therapeutic position comparable to dupilumab.

Clear Aligner Therapy: Evidence, Eloquence and Reality

  • Nikhilesh R. Vaid;Samar M. Adel
    • Journal of Korean Dental Science
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    • 제16권2호
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    • pp.115-127
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    • 2023
  • The demand for orthodontic clear aligner therapy (CAT) has increased significantly over the last decade, offering advantages over the fixed appliances (FA) including enhanced aesthetics, better hygiene and comfort, along with minimal restrictions on the patient's diet. Moreover, a marked improvement in the efficacy of tooth movement using aligners has been documented. On the contrary, there have been known limitations of CAT including the compliances issues and the apparent lack of efficacy for certain types of tooth movement such as closure of extraction space compared to FA. Thus, evidence-based evaluation of the accuracy of prediction of tooth movement with clear aligners and their ability to effectively perform major tooth and root movements compared to FA are crucial. Although several systematic reviews have investigated various aspects of the effectiveness of CAT, we are yet to obtain a rather conclusive answer to this question. The current review attempted to summarize the evidence-based findings of most systematic reviews about CAT available to date. Major issues regarding the predictability of tooth movement, the role of attachments and auxiliaries in improving the effectiveness of CAT, and the treatment outcomes in comparison to FA were investigated. Clinical recommendation have been also elaborated based on the interpretation of the findings of all systematic reviews included in this study.

Chitosan as a Flocculant: An Approach to Improve its Solubility for Efficient Harvesting of Microalgae

  • Sajjad, Attia;Rizwan, Muhammad;Mujtaba, Ghulam;Rashid, Naim
    • Korean Chemical Engineering Research
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    • 제55권4호
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    • pp.530-534
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    • 2017
  • Chitosan is a promising flocculant for microalgae harvesting, but its scale-up application is not economically supported yet. Low solubility of chitosan in microalgae suspension demands high dosage (as a flocculant) to destabilize the cells, and thus, increases the cost of microalgae harvesting. This study identifies efficient solvents for the chitosan, and optimizes the concentration of solvents and chitosan dose to improve the harvesting efficiency. Chitosan was dissolved in different acids, and subsequently used as a flocculant. The flocculant efficacy was measured in terms of harvesting efficiency and reduction in chemical oxygen demand (COD) of the microalgae suspension. It was found that chitosan dissolved in 0.05 M HCl showed the highest harvesting efficiency ($89{\pm}0.87%$) at only 30 mg/L of dosage. In comparison, 270 mg/L of $FeCl_3{\cdot}6H_2O$ was required to attain $86{\pm}0.083%$ of the harvesting efficiency. $H_2SO_4$ dissolved chitosan required high flocculant dose (150 mg/L) and resulted in relatively low harvesting efficiency ($77{\pm}0.11%$). It was concluded that the efficacy of chitosan is solvent dependent, and the selection of proper solvent can decrease the dosage requirement for microalgae harvesting.

필리핀거주 한국인의 건강증진 생활양식에 영향을 미치는 요인 (A Study on Factors Influencing the Health Promoting Lifestyles of Koreans in the Philippines.)

  • 최순희
    • 기본간호학회지
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    • 제6권3호
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    • pp.369-381
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    • 1999
  • The purpose of this study was to determine the predictors of health promoting lifestyles(Health Promoting Lifestyle Profile HPLP) of Koreans in the Philippines. The sample consisted of 100 Koreans who have lived in Manila, Philippines. Data were collected for two months from Feb, 1 to March 30, 1998. Analysis of the data was done by use of percentage, t-test, ANOVA, Pearson's Correlation Coefficients, and Stepwise Multiple Regression. The results of this study were summarized as follows : 1. The range of total HPLP score was from 73 to 175 and the mean score of that was 117.23. In comparison of mean scores depending on each item of six dimensions, self-actualization dimension tended to show the hightest score(2.98) and responsibility for health dimension, the lowest score(1.83). 2. The HPLP score showed a positive correlation with age(r=.19), social support (r=.39), self-efficacy(r=.52) and perceived health status(r=.27), but a inverse correlation with perceived health care service utilization barriers(r=-.20). 3. By using stepwise multiple regression analysis it was determined that the main influencing factors on the HPLP score were self-efficacy(27.2%), social support(5.3%), age(5.3%) and perceived health status(2.9%). These variables made it possible to explain 40.7% of variance in HPLP score.

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산욕부의 건강증진행위에 영향을 미치는 요인 (A Study on Factors Influencing the Health Promoting Behaviors in Postpartal Women)

  • 조루시아;최순희
    • 기본간호학회지
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    • 제5권2호
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    • pp.353-361
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    • 1998
  • The purpose of this study was to determine the predictors of health promoting behavior in postpartal $4{\sim}6$ week women. The sample consisted of 104 postpartal women who experienced a vaginal delivery at four obstetrical clinics located in Kwangju city. Data were collected for two months from June 1 to July 30, 1997. Analysis of the data was done by use of percentage, t-test, ANOVA, Pearson's Correlation Coeficients, and Stepwise Multiple Regression. The results of this study were summarized as follows : 1. The range of total HPLP score was from 93 to 182 and the mean score of that was 142.28. In comparison of mean scores defending on each item of six demensions, self-actualization demension tended to showed hightest score(3.33) and exercise & rest demension, the lowest score(2.47). 2. The HPLP score was not significantly different defending on the general characteristics. 3. The HPLP score showed a positive correlation with family-support(r=.51) and self-efficacy(r=.41), but a inverse correlation with perceived barriers(r=-.27). 4. By using stepwise multiple regression analysis it was determined that the main influencing factors on the HPLP score were family-support(26%) and self-efficacy (8%). These variables made it possible to explain 34% of variance in HPLP score.

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