• 대한예방한의학회지
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• 제11권1호
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• pp.1-8
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• 2007

Curcumin and its analogues(Tetrahydrocurcumin THC, demethoxycurcumin ; BDMC and dimethoxycurcumin DiMC) were compared for their ability to inhibit the growth of human leukemia HL-60 cells. The growth of HL-60 cells was inhibited by curcumin, DeMC and DiMC, but not by THC lacking ${\alpha},{\beta}-unsaturated$ carbonyl groups thus suggesting that ${\alpha},{\beta}-unsaturated$ carbonyl groups are crucial for antiproliferative activity. The order of antiproliferative activity was DiMC, curcumin and BDMC indicating that the number of methoxy groups on the aromatic rings of the active compounds plays an important role in enhancing anti-proliferating activity. In comparison with cellular uptake of the active compounds, uptake capacity was found to be highest with DiMC, followed by curcumin and BDMC. Therefore, it is most likely that the differential antiproliferative activities of DiMC, curcumin and BDMC are associated with their capacities of cellular uptake resulting in building up of enough concentration inside the cells.

• The Korean Journal of Ecology
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• 제16권3호
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• pp.329-339
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• 1993

Effects of relative light intensity and N, P fertilization on the growth and ramet dynamics of the rhizomatous plants, Arundinella hirta, Miscanthus sinensi and Spdiopogon sibiricus were studied in Chuncheon, Kangweon-Do. Ramets emerged in one pulse a year, withered in one pulse at the end of the growing season in M. sinensis and S. sibircus stands, while the birth and death pulse in A. hirta stands were two times. Total births of ramet were 9 times and 3.6 times greater in the unshaded fertilized stands of A. hirta and M. sinensis than in the shaded, However, those of S.sibiricus were 2.1 times greater in the shaded stands. Flowering rates of A. hirta, M.sinensis and S.sibiricus I the unshaded fertilized stands were 1.8, 2.7 and 1.04 times greater than in the shaded unfertilized stands, respectively. Height of ramets of A. hirta and M.sinensis were the hightest in the unshaded fertilized stands. However, that of s.sibiricus was the highest in the shaded fertilized stand. Aboveground production of A.hirta in the fertilized stand was 2.4 times greater in the unshaded stand than in the shaded one. Results of inflorescence frequency, shoot height and the ratio of aboveground to belowground were smiliar to the total births. The added fertilizer markedly increased the ramet density and the shoot productivity of three rhizomatous plants, especially of A. hirta.

• 한국미생물·생명공학회지
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• 제19권6호
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• pp.543-547
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• 1991

토양으로부터 호알칼리성 미생물을 분리하여 동정 한 결과, Bacillus속의 특성을 나타내어 Bacillus sp. SH-8로 명명하였다. Bacillus sp. SH-8은 초기 pH 9.0이상의 알칼리에서만 생육이 가능하였으며 중성 pH에서는 불가능하였다. Bacillus sp. SH-8로부터 U.V.조사에 의해 중성배지에서도 생육이 가능한 변이주를 분리하여 Bacillus sp. SH-8M으로 명명하였으며, 초기 pH 6.9부터 11.0까지 생육이 가능하였다. 따라서 이들 두 균주는 pH 변화에 따른 생육과 효소생산을 비교, 검토하는데 적합한 균주로 생각된다.

• Journal of Microbiology and Biotechnology
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• 제13권5호
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• pp.651-659
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• 2003

A new method was proposed to control Harmful Algal Blooms (HABs) by a biosurfactant sophorolipid. The effect of sophorolipid on the growth, motility, precipitation, and recovery of algal cells was investigated for four common HAB species, Scripsiella trochoidea, Prorocentrum minimum, Cochlodinium polykrikoides, and Heterosigma akashiwo. The motility and growth of algal cells were inhibited significantly at the concentration of 20 and 5 mg/l sophorolipid, respectively, and no recovery was observed under the above concentrations. The concentration of 20 mg/l sophorolipid was considered to be an effective concentration for the mitigation of HABs. A sedimentation test suggested that the maximum precipitation occurred at the end of 1 h, and the algicidal effect of sophorolipid was observed by a microscope. Comparative study showed that sophorolipid had marked algicidal capability. Analysis on biodegradability, toxicity, and cost effectiveness further demonstrated the potential of sophorolipid in future HABs mitigation.

• 수산해양교육연구
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• 제25권6호
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• pp.1315-1323
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• 2013

The purpose of this research is to evaluate the effects of a commercial mixed extruded pellet(EP) and raw fish moist pellet(MP) diet on diseases prevalence and serological constituents and HSI of korean rockfish, Sebastes schlegeli grown in two commercial-scale aquaculture farms from June to December in 2009. The growth of MP-fed rockfish was slightly faster than EP-fed rockfish during experimental period, but did not show significant differences. The levels of TCHO, TG, Glucose and TP in the MP-fed rockfish group were higher than those of EP-fed group, whereas there was no significant difference in other biochemical factors of blood between two groups. In addition, bacteria and virus were not detected in both MP- and EP-fed rockfish groups, and the infection rates of gill fluke between two groups did not show clear difference. In conclusion, there was no comparable difference in growth and the health extents of one year rockfish by administration of the commercial mixed extruded pellet(EP) and raw fish moist pellet(MP) diets.

• 농촌의학ㆍ지역보건
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• 제27권2호
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• pp.137-148
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• 2002

Objectives: This study was to investigate the needs for developing the health promotion program for elderly and to compare the health promoting lifestyles behaviors and perceived health status of elderly in urban and rural area. Methods: The data was collected from 82 elders in urban(D city) and 77 elders in rural area(C county) by face to face interview. The Health Promoting Lifestyle ProfileII(HPLPII) and Perceived Health Status were used. Results: 1) The total score of HPLP was 2.44. In the subscales, the highest degree of performance was 'nutrition', following 'interpersonal relationship', 'stress management', 'health responsibility' and 'spiritual growth' and the lowest degree of performance was 'physical activity'. 2) Elderly people living in urban area had significantly higher the total HPLP score than elderly people living in rural area The urban elderly had significantly higher the score of HPLP subscales such as 'physical activity', 'interpersonal relationship' and stress management than rural elderly. 3) The mean score of perceived health status was 8.79. There was no significant difference in the perceived health status between urban and rural elderly. Conclusions: The above findings indicate that it is necessary to develop a health promotion program with reinforced physical activity, health responsibility and spiritual growth for elderly people in Korea. Especially the physical activity need to he strengthened for rural elderly.

• KSBB Journal
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• 제27권2호
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• pp.121-126
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• 2012

In order to explore structural features of minoxidil analogs with a view of enhancing lysyl hydroxylase (LH) inhibitory activity, molecular holographic QSAR (HQSAR) and CoMSIA (comparative molecular similarity indices analysis) were performed. The results from the atomic contributions with optimized the HQSAR 6-2 model indicated that, in case of pyrimidine-1-N-oxide substituent, C2 atom of pyrimidine ring and C'3-C'4 bond of 4-piperidinol group showed the highest impact on the inhibitory activity towards LH enzyme. It was also evident from the information of the optimized CoMSIA F5 model that the inhibitory activity mainly depended on the hydrophobic field contribution (36%) and the hydrogen bond (H-bond) field contribution (49.2%) of substrate molecule. Particularly, it is predicted that the functional groups which disfavor H-bond acceptors in large space around the piperidinol group and also the functional groups which favor the H-bond acceptors at C'4 (& C'5) atom in $R_5$ group play a role for increased inhibitory activity. With this in mind, it is likely that a novel candidate having more improved inhibitory activity on hair growth could be designed in the future.

• 농촌지도와개발
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• 제19권3호
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• pp.649-672
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• 2012

The government established Special Accounts for Balanced National Development in 2005, and the Metropolitan Council has enacted and executed ordinance relevant to special accounts to relieve regional unbalanced growth and to promote regional balanced growth. This study derived a political implication through the comparison analysis of the background of establishment and its purpose, the selection criteria of support target, finance scale and tax revenue finance, appropriation target and finance distribution, etc. on the basis of Chungcheongnam-do Special Accounts for Balanced Development and Jeollabuk-do Eastern part Special Accounts among the special accounts implemented in metropolitan council. The major conclusions of this study are as follows. First, the transition from the concept of balanced development to specialized development is necessary for the development of distressed region. Second, the pure wastefulness ratio of the local government's tax revenue finance of special accounts designed concentrating upon special accounts for Wide-area Autonomous Communities development should be gradually expanded. Third, Special Accounting budget should be supported to promote specialized development through the selection and concentration centering around comparatively advantageous resource within the region. Fourth, the strategic special accounts budget application system of cities and counties to utilize the projects of the government and the province to achieve the goal of cities and counties should be prepared.

• 한국환경복원기술학회지
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• 제3권3호
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• pp.37-44
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• 2000

The objective of this study is on suggesting the simulation model of 10 selected plants for the traffic noise barrier through field experiment by computer. The field experiment was carried out at the traffic noise barrier of Honam highway. The results are as follows. 1. It was identified that Paederia scandens, Celastrus Orbiculatus, Lonicera japonica, Wisteria floribunda, Parthenocissus tricuspidata and Parthenocissus quinquefolia grows well vertically and takes 3 years in covering completely. 2. It was identified that Trachelospermum asiaticum and Hedera rhombea, evergreen Climber(vine), grows slowly in comparative with other deciduous Climbers(vine), but give drivers good landscapes in winter. So those have considerable value in the south region of Taejeon. 3. It was identified that Wisteria jl.oribunda, Lonicera japonica, Paederia scandens, Clematis mandschurica and Campsis grandijlora showed good view in flowering period. 4. It was identified that auxiliary materials for inducing growth were needed in other plants except Parthenocissus tricuspidata, Parthenocissus quinquefolia. 5. It was identified that subsequent research about the auxiliary materials for inducing growth and adequate planting distance of each plants is needed for actual application.

• ALGAE
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• 제25권1호
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• pp.27-35
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• 2010

Marked declines in seagrass meadows are increasingly being reported from coasts around Korea and many regions of the world. The transplantation of seagrasses has been attempted to mitigate and control their degradation from a range of anthropogenic factors. In this study, Zostera marina shoots, which were collected from a donor bed in Koje Bay, were transplanted in Jindong Bay in December 2004. In 2008, a comparative investigation of shoot morphology, growth, and reproduction strategy of Z. marina was carried out between the donor and transplant sites to assess their adaptation success. Shoot height, individual shoot weight, and leaf productivity at the transplant site were significantly greater than those at the donor site. However, below-/aboveground tissue ratio was significantly lower at the transplant site compared to the donor site. Z. marina survival was maintained through vegetative reproduction, while peak season for lateral shoot recruitment was late winter for both donor and transplant site populations. However, vegetative reproduction mainly occurred during late winter and spring at the transplant site, whereas lateral shoots were evident across all seasons except late spring in the donor site. More pronounced seasonal variations were found at the transplant site compared to the donor site. These results indicate that Z. marina populations at the two sites possess distinct phenotypic variations induced by different environmental conditions, and Z. marina transplants have adapted well to the new transplant environment.