• Title/Summary/Keyword: common spaces

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Immunohistochemical Observation of Plasma Cell Granuloma in Intraoral Chronic Inflammatory Lesions (구강내 만성염증병소에서 보이는 형질세포육아종의 면역조직화학적 관찰)

  • Kim, Yeon-Sook;Lee, Suk-Keun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.33 no.1
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    • pp.26-31
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    • 2011
  • Purpose: Chronic inflammatory gingival lesions occur as pyogenic granulomas or non-specific chronic suppurative lesions. Methods: Of the 59 chronic inflammatory gingival lesions examined, plasma cell granuloma (n=14), which showed an intense antibody-mediated immune reaction with the increased infiltration of plasma cells, was observed as a pseudotumor-like gingival overgrowth and myofibroblastic or fibrohistiocytitc proliferation of stromal cells with a heavy collection of plasma cells. The levels of CD3, CD20, CD31, CD68, RANKL, cathepsin G, cathepsin K, lysozyme, TNF${\alpha}$, MMP-2, and MMP-9 in the 14 cases of gingival plasma cell granuloma with immunohistochemical detection were measured to determine the pathogenetic progresses of the plasma cell granuloma compared to the common pyogenic granuloma (n=45) in the gingiva. Results: The gingival lesions of the plasma cell granuloma could be divided into three histological types, plasma cell predominant type (PPT, n=8), mixed inflammatory cell type (MICT, n=2), and sclerosed fibrosis type (SFT, n=4). The PPT showed a condensed infiltration of plasma cells into the perivascular spaces of the granulomatous lesion with frequent formation of Russel's body in their cytoplasm. The MICT showed the concomitant infiltration of many macrophages together with plasma cells, resulting in the diffuse destruction of stromal fibrous tissue. The SFT showed granulomatous lesions replaced gradually by thick collagenous fibrous tissue, resembling an inflammatory pseudotumor. The SFT expressed strongly the lymphocytic markers, CD3 and CD20, and the macrophage/monocyte markers, CD31 and CD68, but showed reduced expression of common inflammatory markers, TNF${\alpha}$, cathepsin G, lysozyme, MMP-2, and MMP-9, as well as the reduced expression of osteoclastogenic markers, RANKL and cathepsin K. Conclusion: These results suggest that a gingival plasma cell granuloma shows variable gene expression for cell-mediated immunity and stromal tissue degeneration, undergoing sclerotic fibrosis with a persistent inflammatory reaction.

Combined Adenomatoid Odontogenic Tumor and Calcifying Epithelial Odontogenic Tumor in the Mandible: Case Report (하악 소구치 부위에 발생한 석회화상피성치성종양이 혼재된 선양치성종양: 증례보고)

  • Noh, Lyang-Seok;Jo, Hyung-Woo;Choi, So-Young;Kim, Chin-Soo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.33 no.2
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    • pp.176-179
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    • 2011
  • Adenomatoid odontogenic tumors represent 3 to 7 percent of all odontogenic tumors. These tumors are more common in the maxilla than the mandible and usually include the anterior region. Clinically, the most common symptom is painless swelling and the tumor is associated with an unerupted tooth, typically a maxillary or mandibular cuspid. The adenomatoid odontogenic tumor appears radiographically as a unilocular radiolucency around the crown of an impacted tooth, resembling a dentigerous cyst. More often, it contains fine calcifications. Histopathologically, there is a thick wall cystic structure with a prominent intraluminal proliferation of the odontogenic epithelium. The most striking pattern is varying-sized solid nodules of spindle-shaped or cuboidal epithelial cells forming nests or rosette-like structures with minimal stromal connective tissues. Conspicuous within the cellular areas are structures of tubular or duct-like appearance. The duct-like spaces are lined with a single row of cuboidal or low columnar epithelial cells, of which the ovoid nuclei are polarized away from the luminal surface. Small foci of calcification may also be scattered throughout the tumor. These have been interpreted as abortive enamel formations. In some adenomatoid odontogenic tumors, the material has been interpreted as dentoid or cementum.

A Study on the Design Transform of the Modern Architecture Renovation (근대건축물 리노베이션에 의한 디자인 변형에 관한 연구)

  • Lee, Sung-Ho;Oh, In-Wook
    • Korean Institute of Interior Design Journal
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    • v.20 no.1
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    • pp.98-108
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    • 2011
  • As people abroad have been much interested in the usage of modern architecture from the early days, many researches about various methods of using them have been progressed. In Korea, with the need to protect the modern architecture through active usage of them in the dimension of protecting the disappearing history, at present, many modern architectures were renovated and used. This research is to find out the sense of direction about the changes of design of the renovated modern architectures in Korea by analyzing the design changes after the renovations in Korea and abroad. Under the limitation of the modern architecture renovation case in Korea, Japan and China, the changes of design after the modern architecture renovation in Korea and aborad were analyzed by the analysis of the ways of remodelling for each case according to the case analyzing frame. Based on the reasons of renovations which had purpose of preserving social history with many other various reasons in common in both cases of Korean modern architecture remodelling and abroad, the common direction of design is to meet new with old to preserve the special image though they did it in different ways. However, different from the case of Japan and China which are coexisting present and past in space, Korean case focused too much on outside, which resulted in only outside designs. In the case of Korea, the past should have mutual understanding to have the firm space image by forming unique interior space culture through the architectural grafting the present in the past not only in the outside space but also in the indoor space. In another words, for the various changes of design in Korean modern architecture renovations, a systematic research should be done about the interior spaces of present architecture and modern architecture.

A Study on the Phenomenological Characteristics of the Expression in Composition of the Experimental Exhibition Space - Focused on Exhibition Utilizing Light - (전시체험공간 구성에서의 현상학적 표현특성에 관한 연구 - 빛을 이용한 전시를 중심으로 -)

  • Park, Eun-A;Han, Hae-Ryon
    • Korean Institute of Interior Design Journal
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    • v.22 no.3
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    • pp.183-194
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    • 2013
  • Exhibition space emphasizes the experience in the space rather than viewing or appreciation of visitors. Because the experience spaces in today's life are limited, people experience rest, comfort, and sometimes extraordinary space experience through exhibition space. Exhibition space has changed from a static place to a space where visitors move and act with the exhibits to freely feel the space. Also, the static space expressed only with illumination and shadow becomes a new space different from daily space for users. This study analyzes the characteristics of phenomenological expression through such user-oriented exhibition space. This study is to analyze the characteristics of phenomenology through the exhibition experience space structure. It is to analyze and study on the characteristics of phenomenological expression of the exhibition experience space structure centered in the opinion of Merlo-Ponti that considers the experience of body among 'characteristics' discussed based on the study of the phenomenological experience published up to date and the viewpoint of Steven Hall that sees light as a subject of creating the space. This study is also considers how the perception of the experiencer is built in the correlation between the phenomenology and exhibition experience space by studying the relationship of the experiencer that is the common point of the exhibition experience space structure and the characteristics of phenomenological expression and analyzing the common point and difference of them. It also focuses on the space of dark whether forming any light rather than looking at the light which is the sense factor among the characteristics of phenomenological expressions. Thus, the purpose of this study is to analyze the case on whether there is any light or not applied to the exhibition experience space grounded by the theoretical materials of Merlo-Ponti and Steven Hall based on the characteristics of phenomenological expressions in the exhibition experience space structure and, based on the result, to set up the basics on the characteristics of phenomenological expressions in the composition of exhibition experience space.

A Study on the Comparison and Characteristics of Public Standard Housing Unit Plan before and after the Independence from the Japan Occupation (광복전후(光復前後) 공영주택(公營住宅)의 평면비교(平面比較)와 변화특성(變化特性)에 관한 연구(硏究))

  • Yoo, Jae-Woo
    • Journal of architectural history
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    • v.11 no.2 s.30
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    • pp.23-35
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    • 2002
  • Even though there have been greate changes in the types and contents of the housing plan in Korea since the Modem age, it seems that the identity of traditional dwelling culture is still remains within it. The purpose of this study is to examine the characteristics and features in the development of the 'Public Standard' Housing Unit Plan by comparing the differences and similarities in unit plans in housings built on Japanese occupation period and those built after the period. From the study, we can conclude as follows: 1. The public standard housing unit plans on both periods have shown the common features in the composition of their physical forms in the way that the front-row area still remains the traditional housing culture and the rear-row area reflects the desires of the modem lives. The structure of the dual-row unit plan appeared in the public standard housing plan was caused by the cultural acculturation in Japanese occupation period. 2. The public standard housing unit plans, however, show the differences in the contents and meaning in units plans with the them of the Japanese housing because of the cultural differences. These differences took placed autonomously through the change of housing plans in the modern time, and have the common features such that 1) the changes in the Maru-centered plan type differ in composition from the inner-corridor plan type used Japanese housing, and 2) the composition of the open-inner spaces in the double-row housing plan reflects the single-row outer open space In the traditional housing. All of these cultural progresses in the public standard housing unit plans was took place as the result of the inner-oriented and notional circulations derived from the modernity. However, the transformed unit plans still contains the identity derived from the variation of the traditional Korean building elements such as Maru and Ondol. In other words, those are the Maru-centered and composed housing plans with juxtaposition of the inner block and the outer block. As the conclusion, though the public standard dwelling unit plan has the similarity in the physical form, it is different in the cultural Identity and meaning from the public standard plans before the independence from the Japan occupation.

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Morphological Changes of Bones and Joints with Rheumatoid Arthritis and Osteoarthritis

  • Hong, Yun-Kyung;Javaregowda, Palaksha Kanive;Lee, Sang-Kil;Lee, Sang-Rae;Chang, Kyu-Tae;Hong, Yong-Geun
    • Reproductive and Developmental Biology
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    • v.35 no.2
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    • pp.143-149
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    • 2011
  • Arthritis is a common disease in aged people, and is clinically divided into rheumatoid arthritis (RA) and osteoarthritis (OA). Although common symptoms such as pain are present, the underlying pathological mechanisms are slightly different. Therefore, the objectives of the present study were to compare joint damage induced by RA and OA by analyzing the major morphological and molecular differences, and to propose a suitable therapeutic intervention based on the pathophysiological conditions of bones and joints. For the RA animal model, 8-week-old DBA1/J mice were immunized with bovine type II collagen emulsified in complete Freund's adjuvant (CFA). Normal C57BL/6 mice (over 2 years of age) were used for OA. The clinical arthritis score was calculated using a subjective scoring system, and paw thicknesses were measured using calipers. The serum TNF ${\alpha}$ level was analyzed using an ELISA kit. Micro-CT was used to identify pathological characteristics and morphological changes. In collagen-induced RA mice, there were increased ankle joint volumes and clinical scores (p<0.01). The concentration of TNF ${\alpha}$ was significantly increased from 3 to 7 weeks after immunization. Micro-CT images showed trabecular bone destruction, pannus formation, and subchondral region destruction in RA mice. OA among aged mice showed narrowed joint spaces and breakdown of articular cartilage. This study suggests that a careful therapeutic intervention between RA and OA is required, and it should be based on morphological alteration of bone and joint.

A Study on the Space Analysis of Apartment Floor Plans in New·Old Town Using the Space Syntax (공간구문론을 이용한 신·구 신도시 아파트의 평면 구성 비교 분석)

  • Hwang, Yong-Woon
    • Korean Institute of Interior Design Journal
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    • v.25 no.2
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    • pp.123-130
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    • 2016
  • Industrialization and Urbanization caused a great influx of rural population into the cities, which caused housing types to change from detached homes to more apartments homes. The official 2014's Statistics (http://kossir.kr) show that half (49.6%) of the Korean population live in apartment buildings and 37.5% live in detached houses. For this reason, the apartments have become the typical housing in Korea. So, the aim of this study is to compare and analyze the internal apartment space of Budang (New-Town) and Wirye (New-Town), since these Budang apartments are the first new-town housing and Wirye apartments are the last new-town housing in Korea. I have used the Convex Analysis of Space Syntax Program in analyzing the inside space of both of these locations' apartments. The results are as follows : First, the inside space of Wirye apartments have more convex space than that of the Budang apartments. Second, the common inside space of the Budang apartments were planned by integration space, on the other hand the inside space of Wirye apartments were planned by segregation space. Third, the master bedroom in both of the locations' apartments were analyzed for their strong integration space which they may have in common. The K (Kitchen) + D (Dining) space in Budang apartments are classified as integration space, on the other hand L (Living) + K + D space is also classified as integration space. The L+K+D space of the Wirye apartments is classified as integration space. Finally, the inside space of the Wirye apartments were planned more for various spaces than that of Budang apartments. The concept of master bedroom in both new-town was not planed for a couple privacy space but the heart of the family.

The Sense of Outdoor Characteristics on the Shopping Mall Planning -Focusing on Common Space Comparison- (쇼핑몰의 야외성 발현 특성에 관한 연구 -공용공간 비교를 중심으로-)

  • Cho, Hun Hee;Oh, Joon-Gul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.3
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    • pp.557-566
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    • 2018
  • Shopping malls have been developed to increase sales revenue and attract visitors. This study focused on the sense of the outdoor characteristics of these shopping malls by comparing open and enclosed types of shopping malls in common spaces in LA and Korea through case study analyses. This research through case studies will form the foundation of comfortable shopping mall space design. The results are the follows. 1. Enclosed shopping malls tend to provide large indoor space to create a sense of outdoors. 2. The common space of enclosed shopping malls is developed through space expansion with horizontal and vertical connections that appear in different combinations depending on the space constraints and contexts. 3. The architectural planning of enclosed shopping malls are largely dependent on the concept of everyday life portrayed in the identity of each space, which usually involve the inclusion of sizable atriums to host indoor sports or special performances.

A Study on the Application of cinematic Construction in the Problem Solving Process of Space Design (공간디자인 문제해결 과정에 있어서 영화구조의 적용에 관한 연구)

  • 문선욱
    • Korean Institute of Interior Design Journal
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    • no.16
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    • pp.42-48
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    • 1998
  • Contemporary space design has based on the framework of academic standards on a number of scientific propositions in order to find out correlation of human and environment and closely examine approaches of a normative design. However the contents are enormous and introductory and have limitation of application to practical business affairs so that we will have to understand them as a thinking to explain the design with,. Therefore this study is an experimental research making use of concrete design approaches applicable to the area of space design ad cinematic construction as a medium. The purpose and significance of it lies in examining its validity and contributing to the future development of space design. Accordingly this study conducted the research through a literature survey for the understanding of space perception in the cinema deduced the language of design concept according to it examined the basic unit of cinematic construction then analyzed the cases of practical architectural spaces. The findings of this study indicate that human's perception to space and the cinema is deduced as a common conceptual language characterized by the ideas of articulation scenery and timeness. These concepts are very organic and interdependent and can probably become a means for human to appropriately analyze an behavior attribute type of investigating environment with. Also in composing space the basic units of cinematic construction can be as instrument to be easily applied to practical affairs as they are correlated with the function of space and a constituent language to be reasonably designed.

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Knowledge Distributed Robot Control Framework

  • Chong, Nak-Young;Hongu, Hiroshi;Ohba, Kohtaro;Hirai, Shigeoki;Tanie, Kazuo
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.1071-1076
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    • 2003
  • In this work, we propose a new framework of robot control for a variety of applications to our unstructured everyday environments. Programming robots can be a very time-consuming process and seems almost impossible for ordinary end users. To cope with this, this work is to provide a software framework for building robot application programs automatically, where we have robots learn how to accomplish a commanded task from the object. An integrated sensing and computing tag is embedded into every single object in the environment. In the robot controller, only the basic software libraries for low-level robot motion control are provided from the robot manufacturer. The main contributions of this work is to develop a server platform that we call Omniscient Server that generates the application programs and send them to the robot controller through the network. The object-related information from the object server merges into robot control software to generate a detailed application program based on the task commands from the human. We have built a test bed and demonstrated that a robot can perform a common household task within the proposed framework.

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