• The Journal of Pediatrics of Korean Medicine
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• v.25 no.2
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• pp.102-110
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• 2011

Objectives: The purpose of this study is to analyze the baby bath preparation and provide necessary information on the upcoming herbal bath preparation for atopic dermatitis. Methods: We selected 113 baby bath preparation by searching typing in "baby bath preparation" in 6 major web-search-engines, and 17 web shopping malls in Korea. 11 items were evaluated under three criteria : type of product, function and ingredient of goods. Results: Result showed that the most common type of bath preparation were liquid type. 96% of the products contained medical agents. Ingredients of the medical agents were herbal medicine, aroma oil, spring and sea ingredients, vitamin and extract. 33% of the products were bath preparation for the atopic dermatitis and 74% of the products were only for the baby. Conclusions: It is necessary to make a government level guideline for natural materials used in bath preparation, and to develop new products contained herbal medicine abide by oriental medical theory.

• The Journal of Korean Medicine
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• v.19 no.1
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• pp.19-26
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• 1998

The purpose of present study is to clarify the differences between EIslwitzia Ciliata (Thunb.) Hylander(향유) and Elsholtzia splendens Nakai ex F. Maekawa (꽃향유) for standardization and the proper usage as medicinal herbs. The major ingredients of both species were isolated by distillation and extraction. The qualitative and quantitative analyses of major distillates were carried out by the use of GC/MS. There was a significant difference between the components of Elsholtzia ciliata and Elsholtzia splendens in the aspects of major components. Several common ingredients were identified as linalool, cumene, elsholtzia ketone, naginata ketone isomer, naginata ketone, myristicin, and sesquiterpene alcohol. Comparison between Elsholtzia. ciliata and Elsholtzia splendens was done in the aspect of major compounds. Myristicin (33.7%) has been shown to be the major component in Elsholtzia ciliata whereas naginata ketone isomer (26.1%) was believed to be a major ingredient in Elsholtzia splendens. The elsholtzia ketone was also one of the major differentiating factors between Elsholtzia splendens and Elsholtzia ciliata, and the quantity is 15.1% in Elslwltzia splendens compared to 2.87% in Elsholtzia ciliata. Moreover, in the Elsholtzia splendens, 4- vinylguaiacol and isoosmorhizole were absent, but both compounds were present in the EIsholtzia ciliata.

• YAKHAK HOEJI
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• v.56 no.4
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• pp.236-239
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• 2012

The aim of present study was to investigate the possible influence and the related mechanism of Cinnamomum cassia derived-cinnamaldehyde on the inflammation or nociception. Cinnamomum cassia was referred to be treated for common cold or dyspepsia in the traditional medicine. However, there are no reports on the antinociceptive or anti-inflammatory properties of cinnamaldehyde, the primary ingredient of Cinnamomum cassia. We hypothesized that cinnamaldehyde would play a role in the modulation of inflammation or nociception evoked by carrageenan, acetic acid or heat. Male Institute of Cancer Research mice were used and the size of edema, frequency of writhing and latency of abnormal behaviors such as licking, flicking, shaking or jumping were measured and recorded. The present study was carried out to evaluate the antiinflammatory and antinociceptive effects of cinnamaldehyde. The administration of cinnamaldehyde (30 and 100 mg/kg) inhibited carrageenan-induced paw edema only at the final phase, suggesting the blockade of synthesis or release of prostaglandins. It also reduced the frequency of the acetic acid-induced writhing reflex in mice. In addition, the administration of cinnamaldehyde prolonged the latency for extraordinary reaction at the hot plate in mice. In conclusion, cinnamaldehyde has anti-inflammatory and analgesic properties and is a potential therapeutic for inflammation and nociception.

• The Journal of Korean Medical History
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• v.34 no.2
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• pp.65-77
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• 2021

Lee Jema said in his book, Dongui Susebowon, that the prescriptions for Soum constitutional type were already developed by doctors during the Song Jin Yuan China around 10th-13th century. Those prescriptions were common techniques that were used throughout the East Asian region. Among them, Lee Jema specially selected some candidate formulas and modified them according to his constitutional theory. This study investigated how similar his modified prescriptions to original formulas through database[ancient formula database] analysis. 24 out of 24 Soum prescriptions selected meaningful ingredient herbs from the original formula. A 50% or higher concordance rate compared to the original formulas. There are only 9 treatment prescriptions that cannot be checked in the ancient formula database. A future task will be to reveal the practical meanings of the ingredients Lee Jema adjusted for the Soum constitutional type patients.

• Journal of Microbiology and Biotechnology
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• v.29 no.6
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• pp.877-886
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• 2019

Brewing with buckwheat as an ingredient has been proven to be successful in several previous studies. However, few studies have focused on the effects of buckwheat on the rutin content and antioxidant activity of beer. In order to develop a lager beer with high rutin content and desirable sensory characteristics, tartary buckwheat malt was used as a brewing adjunct. The results showed that the rutin-degrading enzyme was the key factor affecting the rutin content in the wort and beer. Compared to beer made using the common mashing method, the rutin content in the buckwheat beers produced using an improved mashing method was approximately 60 times higher. The total flavonoid contents in buckwheat beers also depended strongly on the mashing methods, ranging from 530.75 to 1,704.68 mg QE/l. The rutin-rich beers also showed better oxidative stability during forced-aging. Meanwhile, the buckwheat beers were found to be acceptable in terms of the main quality attributes, flavor, and taste.

• Animal Bioscience
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• v.35 no.2_spc
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• pp.347-355
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• 2022

Among edible insects, black soldier fly (Hermetia illucens), yellow mealworm (Tenebrio molitor), and common housefly (Musca domestica) have been considered as an alternative protein source for pigs. Because they are easy to breed and grow in the organic wastes, and they have well-balanced nutritional value as a protein source for pigs. The black soldier fly larvae and mealworm could replace the fish meal in the diets for weaned pigs without adverse effects on growth performance and nutrient digestibility. Black soldier fly could also be included in the finishing pig's diet without any negative effects on the growth performance and pork quality of the market pigs. Insect products showed a greater standardized ileal digestibility value of amino acids than conventional animal proteins in growing pigs. Due to the limited amount of insect products used for pig feeding study, most previous pig studies have been conducted in weaned pigs. Thus, further study is needed about the optimal inclusion level of insect products in every phase diet from weaned pigs to sows. The use of insect products in swine diets has some challenges in terms of cost, supply, and safety. Lastly, intrinsic differences among insect species, processing method, and feeding phase should be taken into consideration for the use of insect products in the swine diets.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.6
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• pp.415-425
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• 2022

Memory formation in the hippocampus is formed and maintained by circadian clock genes during sleep. Sleep deprivation (SD) can lead to memory impairment and neuroinflammation, and there remains no effective pharmacological treatment for these effects. Myricetin (MYR) is a common natural flavonoid that has various pharmacological activities. In this study, we investigated the effects of MYR on memory impairment, neuroinflammation, and neurotrophic factors in sleep-deprived rats. We analyzed SD-induced cognitive and spatial memory, as well as pro-inflammatory cytokine levels during SD. SD model rats were intraperitoneally injected with 10 and 20 mg/kg/day MYR for 14 days. MYR administration significantly ameliorated SD-induced cognitive and spatial memory deficits; it also attenuated the SD-induced inflammatory response associated with nuclear factor kappa B activation in the hippocampus. In addition, MYR enhanced the mRNA expression of brain-derived neurotropic factor (BDNF) in the hippocampus. Our results showed that MYR improved memory impairment by means of anti-inflammatory activity and appropriate regulation of BDNF expression. Our findings suggest that MYR is a potential functional ingredient that protects cognitive function from SD.

• Journal of Applied Biological Chemistry
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• v.65 no.3
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• pp.167-172
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• 2022

Pathophysiological reaction of platelets in the blood vessel is an indispensable part of thrombosis and cardiovascular disease, which is the most common cause of death in the world. In this study, we performed in vitro assays to evaluate antiplatelet activity of artemether in human platelets and attempted to identify the mechanism responsible for protein phosphorylation. Artemether is a derivative of artemisinin, known as an active ingredient of Artemisia annua, which has been reported to be effective in treating malaria, and is known to function through antioxidant and metabolic enzyme inhibition. However, the role of artemether in platelet activation and aggregation and the mechanism of action of artemether in collagen-induced human platelets are not known until now. In this study, the effect of artesunate on collagen-induced human platelet aggregation was confirmed and the mechanism of action of artemether was clarified. Artemether inhibited the phosphorylation of PI3K/Akt and Mitogen-activated protein kinases, which are phosphoproteins that are known to act in the signal transduction process when platelets are activated. In addition, artemether decreased TXA₂ production and decreased granule secretion in platelets such as ATP and serotonin release. As a result, artemether strongly inhibited platelet aggregation induced by collagen, a strong aggregation inducer secreted from vascular endothelial cells, with an IC₅₀ of 157.92 μM. These results suggest that artemether has value as an effective antithrombotic agent for inhibiting the activation and aggregation of human platelets through vascular injury.

• Korean Journal of Agricultural Science
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• v.51 no.3
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• pp.251-260
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• 2024

Sucrose is a common disaccharide sugar that is used in pig diet mainly as an energy source as well as to improve the palatability of diet. This study investigated the effects of dietary sucrose supplementation on the growth performance, nutrient digestibility, fecal score, and serum cortisol of growing pigs. A total of 96 growing pigs were randomly allocated into three treatment groups (8 repetitions per treatment, 4 pigs per pen). Dietary treatments included: control (CON), basal diets; treatment 1 (TRT1), basal diet with 0.75% sucrose; and treatment 2 (TRT2), basal diet with 1% sucrose. Dietary sucrose supplementation tended to improve (p < 0.10) the average daily gain compared to CON group. Moreover, increased (p < 0.05) feed intake was found in the sucrose supplemented group compared to the CON group. In comparison to the CON diet the nutrient digestibility of energy tended to increase (p < 0.10) by sucrose supplemented diet. Fecal score was not altered through dietary sucrose supplementation. Decreased (p < 0.05) serum cortisol was found in both the 0.75% sucrose and 1% sucrose supplemented diet than the CON diet. In conclusion, sucrose can be a suitable feed ingredient for growing pigs as it can improve the palatability of diet as well as feed intake, energy digestibility and reduce stress through reducing serum cortisol.

• Journal of Mushroom
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• v.13 no.3
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• pp.250-255
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• 2015

In this study spent mushroom substrate has ingredient raising rice bed soil. spent mushroom substrates are organic content is 60.72% were nitrogen - phosphoric acid - potassium is 1.39 - 0.89 - 0.81% of the chemical characteristics determine. Post-harvested mushroom substrates of the stabilization process, the temperature of the 20 days time progress in the pH of the rise and fall of temperature down were germination index also 77, as identified, Spent mushroom substrate bed soil for raising rice Ingredient to take advantage of the 20 days or more stabilization process needed to be investigated. Rice seed germination characteristic is in the common bed soil for raising rice ingredients manufactured control group and the comparison in spent mushroom substrate is 10% or less of a mixed experimental population of the germination rate is 82% was more than average days to germination and germination energy, even a statistical significant difference is or control group than good level was ok. Growth initial also spent mushroom substrate is 10% or less of a mixed experimental population of shoot dry matter (top) and grave less than control group higher as confirmed spent mushroom substrates are bed soil for raising rice ingredients are likely to take advantage of the high, as was the judge.