• 제목/요약/키워드: common factors

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전뇌허혈 유발 후 침전극저주파자극 적용이 소뇌의 세포자멸사 억제에 미치는 영향 (The Effect of Needle Electrode Electrical Stimulation Following Global Ischemia on the Suppression of Apoptosis in the Cerebellum)

  • 왕중산;박주현;문옥곤;김년준;최정현;김지성
    • 한국전자통신학회논문지
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    • 제8권12호
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    • pp.1949-1958
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    • 2013
  • 본 연구는 온목동맥의 일시적 폐색에 의해 유발된 전뇌허혈로 인해 발생한 SD 랫드 소뇌 부위의 세포자멸사에 대한 침전극저주파자극(Needle Electrode Electrical Stimulation : NEES) 적용의 효과를 알아보기 위하여 면역조직화학적검사법을 통하여 조직을 관찰하였다. 연구를 통하여 대조군과 전뇌허혈유발군, 침전극저주파자극시행군의 세포자멸사 관련 인자의 발현정도를 비교하여 분석한 결과 전뇌허혈 후 침전극저주파의 적용은 SD 랫드 소뇌 부위의 c-fos 발현 감소에 유의한 효과를 보였으며, bax, caspase-3의 발현 감소에는 유의한 영향이 없는 것으로 나타났다. 이상의 결과로 보아 전뇌허혈 후 침전극저주파자극의 적용은 세포자멸사 관련 인자의 발현 억제에 일부분 효과성이 있는 것으로 사료된다.

한복의 세계화를 위한 방안 연구 -세계패션명품, 동양 각국의 성공사례를 중심으로- (A Study on Improvement for Globalization of Hanbok -Focused on the Successful Cases in Luxury Fashion Brands and Asian Nations-)

  • 채금석
    • 한국의류학회지
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    • 제31권9_10
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    • pp.1418-1430
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    • 2007
  • To strength global competitivenss and raise reputation in times of globalization, the practical use and development of traditional culture which must be discriminated against other countries wedging their ways. The purpose of this study is, 1. Make the mutual relationship between globalization of Korean traditional clothing(Hanbok) and the strean of the international fashion clear. 2. Deduce a common primary fact through commonness of international great products and a success of globalization in Asian nations 3. Suggest a scheme for globalization of Korean traditional clothing from the flank of a design and a policy on the basis of analysis. The consequence of this study is, 1. In the situation that modern international fashion focused Re-Orienting Fashion, Korean traditional clothing-Hanbok is considered as the most priceless value of application for an effective design sauce to differentiate.2. The common point between International leading fashion brands and success of globalization of each Asian nation is to pursuit an effective marketing strategy through a proper harmony with a differentiated 'uniqueness' which is motivated from their tradition, a sense of modern trend reading, and a 'generality' which fits in their lige styles. In consequence, we must develop typical design factors to be connected directly with Korean traditional image from the flank of design, For this, the typical design factors need to be applied with grafting tradition and modern ideas, simplicity, convenience, fleshly senses, and youth.

세계측지계 전환활성화를 위한 변환방법 연구 (A study on the coordinates conversion procedures to activate the transformation of local into world geodetic reference system)

  • 홍창기;권재현;이현직;이원진
    • 한국측량학회지
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    • 제27권1호
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    • pp.677-682
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    • 2009
  • 개정된 측량법에 의해 2010년부터 모든 위치정보좌표는 세계측지계 좌표를 기준으로 하여야 하며 이를 위해 국토지리정보원을 중심으로 세계측지계로의 전환을 위한 기술적 제도적 기반을 마련하였다. 하지만 여러 저해요인으로 인해 현재 지방자치단체별 전환실적이 상대적으로 미흡한 실정이다. 본 연구에서는 세계측지계로의 전환에 필요한 요소 중 좌표변환방법 및 절차에 대한 분석을 통해 보다 유연성 있는 변환방법을 제시하였으며 기존의 좌표변환절차 중 효율적 인 좌표변환을 위한 보완방안을 제공하였다. 이를 위해 국가변환계수를 이용한 기존의 변환방법보다 효율적인 Affine변환의 유용성 여부를 분석하였으며 기준점의 허용오차 분석을 통해 공통점에 존재하는 비상사점의 판별 기준을 제시하였다. 또한 구성과 및 신성과가 혼재하는 지역에서의 효율적인 세계측지계 좌표변환 방법 및 세계측지계 변환에 필요한 공통점의 적절한 수량을 제시하였다.

Blunt Traumatic Cardiac Rupture: Single-Institution Experiences over 14 Years

  • Yun, Jeong Hee;Byun, Joung Hun;Kim, Sung Hwan;Moon, Sung Ho;Park, Hyun Oh;Hwang, Sang Won;Kim, Yong Hwan
    • Journal of Chest Surgery
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    • 제49권6호
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    • pp.435-442
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    • 2016
  • Background: Blunt traumatic cardiac rupture is rare. However, such cardiac ruptures carry a high mortality rate. This study reviews our experience treating blunt traumatic cardiac rupture. Methods: This retrospective study included 21 patients who experienced blunt traumatic cardiac rupture from 1999 to 2015. Every patient underwent surgery. Several variables were compared between survivors and fatalities. Results: Sixteen of the 21 patients survived, and 5 (24%) died. No instances of intraoperative mortality occurred. The most common cause of injury was a traffic accident (81%). The right atrium was the most common location of injury (43%). Ten of the 21 patients were suspected to have cardiac tamponade. Significant differences were found in preoperative creatine kinase-myocardial band (CK-MB) levels (p=0.042) and platelet counts (p=0.004) between the survivors and fatalities. The patients who died had higher preoperative Glasgow Coma Scale scores (p=0.007), worse Trauma and Injury Severity Scores (p=0.007), and higher Injury Severity Scores (p=0.004) than those who survived. Conclusion: We found that elevated CK-MB levels, a low platelet count, and multi-organ traumatic injury were prognostic factors predicting poor outcomes of blunt cardiac rupture. If a patient with blunt traumatic cardiac rupture has these factors, clinicians should be especially attentive and respond promptly in order to save the patient's life.

셰어하우스의 선호도 영향요인에 관한 연구 - 잠재적 이용자인 대학생, 대학원생을 중심으로 (A Study on the Factors Affecting the Preference of a Share House)

  • 황춘화
    • 한국콘텐츠학회논문지
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    • 제20권5호
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    • pp.90-104
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    • 2020
  • 현대의 세계 경제는 소유 중심적인 상업경제에서 가치 공유의 공유경제로 변화하는 추세이다. 현대 사회에서 1인 가구는 일반적인 가구 유형으로 자리매김하고 있다. 1인 가구의 증가 원인은 초혼 연령 상승으로 인한 독신 인구의 증가, 평균 수명 연장으로 인한 노인 인구의 증가, 혼인 감소, 이혼 증가, 기러기 아빠, 직장으로 인한 주거지 분리 등으로 최근에는 다양한 형태의 1인 가구가 증가하고 있다. 특히 1인 가구의 상당한 비율이 청년층이 차지하고 있고 이러한 현상이 대도시에서 흔히 나타난다. 청년층의 1인 가구의 수가 증가하면서 1인 가구의 주거수요에 대한 새로운 수요가 발생하였다. 본 연구는 1인 가구 주거수요의 하나의 대안으로 셰어하우스의 선호도 영향요인에 대한 실증분석을 하여 셰어하우스 선호도에 어떠한 요인들이 영향을 미치는 가를 파악함에 그 목적이 있다. 실증분석 결과 셰어하우스 접근성, 건축물 특성, 셰어하우스 운영 특성은 모두 선호도에 유의한 영향을 미쳤다.

Demographic Risk Factors, Affected Anatomical Sites and Clinicopathological Profile for Oral Squamous Cell Carcinoma in a North Indian Population

  • Krishna, Akhilesh;Singh, R.K.;Singh, Shraddha;Verma, Pratima;Pal, U.S.;Tiwari, Sunita
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권16호
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    • pp.6755-6760
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    • 2014
  • Background: Oral cancer is a common form of cancer in India, particularly among men. About 95% are squamous cell carcinomas. Tobacco along with alcohol are regarded as the major risk factors. Objectives: (i) To determine associations of oral squamous cell carcinoma (OSCC) with respect to gender, age group, socioeconomic status and risk habits; (ii) To observe the distribution of affected oral anatomical sites and clinico-pathological profile in OSCC patients. Materials and Methods: This is an unmatched case-control study during period January 2012 to December 2013. Total of 471 confirmed OSCC patients and 556 control subjects were enrolled. Data on socio-demography, risk habits with duration and medical history were recorded. Results: There were significant associations between OSCC with middle age (41-50years; unadjusted OR=1.63, 95%CI=1.05-2.52, p=0.02) (51-60 years; unadjusted OR=1.79, 95%CI=1.15-2.79, p=0.009) and male subjects (unadjusted OR=2.49, 95%CI=1.89-3.27, p=0.0001). Cases with both habits of tobacco chewing and smoking were at a higher risk for OSCC than tobacco chewing alone (unadjusted OR=0.52, 95%CI=0.38-0.72, p=0.0001), duration of risk habits also emerged as a responsible factor for the development of carcinoma. The majority of patients were presented in well-differentiated carcinomas (39.9%). Prevalence of advance stages (TNM stage III, IV) was 23.4% and 18.3% respectively. The buccal mucosa was the most common (35.5%) affected oral site. Conclusions: In most Asian countries, especially India, there is an important need to initiate the national level public awareness programs to control and prevent oral cancer by screening for early diagnosis and support a tobacco free environment.

대학병원 보건의료인의 근골격계 증상 관련요인 (Related Factors of Musculoskelectal Symptoms in University Hospital Workers)

  • 한경아
    • 한국산학기술학회논문지
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    • 제16권3호
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    • pp.1928-1936
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    • 2015
  • 본 연구는 대학병원 보건의료인을 대상으로 직무 관련 요인들과 근골격계 증상간의 관련성을 살펴보았다. 연구대상은 대학병원 보건의료인 313명이며, 자료분석은 SPSS/PC 21.0을 이용하여 기술통계, 로지스틱 회귀분석으로 분석하였다. 연구결과 근골격계 통증을 호소하는 대상자는 201명(64.2%)였다. 신체 부위별 근골격계 통증에서는 어깨부위가 116명(37%)로 가장 많았다. 또한 35세 미만인 경우와 근무경력 6년 이상, 육체적 부담정도가 많을수록 근골격계 통증 호소율이 높은 것으로 나타났다. 결론적으로 근골격계 증상이 질환으로 진행되지 않도록 예방하기 위해서는 직종과 근무경력에 따른 예방활동을 계획하거나, 업무 중에 수행할 수 있는 스트레칭 등의 중재와 지속적이고 적극적인 관리가 필요하다.

Mortality and Epidemiology in 256 Cases of Pediatric Traumatic Brain Injury : Korean Neuro-Trauma Data Bank System (KNTDBS) 2010-2014

  • Jeong, Hee-Won;Choi, Seung-Won;Youm, Jin-Young;Lim, Jeong-Wook;Kwon, Hyon-Jo;Song, Shi-Hun
    • Journal of Korean Neurosurgical Society
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    • 제60권6호
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    • pp.710-716
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    • 2017
  • Objective : Among pediatric injury, brain injury is a leading cause of death and disability. To improve outcomes, many developed countries built neurotrauma databank (NTDB) system but there was not established nationwide coverage NTDB until 2009 and there have been few studies on pediatric traumatic head injury (THI) patients in Korea. Therefore, we analyzed epidemiology and outcome from the big data of pediatric THI. Methods : We collected data on pediatric patients from 23 university hospitals including 9 regional trauma centers from 2010 to 2014 and analyzed their clinical factors (sex, age, initial Glasgow coma scale, cause and mechanism of head injury, presence of surgery). Results : Among all the 2617 THI patients, total number of pediatric patients was 256. The average age of the subjects was 9.07 (standard deviation${\pm}6.3$) years old. The male-to female ratio was 1.87 to 1 and male dominance increases with age. The most common cause for trauma were falls and traffic accidents. Age (p=0.007), surgery (p<0.001), mechanism of trauma (p=0.016), subdural hemorrhage (SDH) (p<0.001), diffuse axonal injury (DAI) (p<0.001) were statistically significant associated with severe brain injury. Conclusion : Falls were the most common cause of trauma, and age, surgery, mechanism of trauma, SDH, DAI increased with injury severity. There is a critical need for effective fall and traffic accidents prevention strategies for children, and we should give attention to these predicting factors for more effective care.

Knowledge and Perceptions about Colorectal Cancer in Jordan

  • Taha, Hana;Jaghbeer, Madi Al;Shteiwi, Musa;AlKhaldi, Sireen;Berggren, Vanja
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권18호
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    • pp.8479-8486
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    • 2016
  • Background: Colorectal cancer (CRC) is the third most common cancer globally. In Jordan, it is the number one cancer among men and the second most common cancer among women, accounting for 15% and 9.4% respectively of all male and female diagnosed cancers. This study aimed to evaluate the knowledge and perceptions about colorectal cancer risk factors, signs and symptoms in Jordan and to provide useful data about the best modes of disseminating preventive messages about the disease. Materials and Methods: A stratified clustered random sampling technique was used to recruit 300 males and 300 females aged 30 to 65 years without a previous history of CRC from four governorates in Jordan. A semi-structured questionnaire and face to face interviews were employed. Descriptive and multivariate analysis was applied to assess knowledge and perceptions about CRC. Results: Both males and females perceived their CRC risk to be low. They had low knowledge scores about CRC with no significant gender association (P=0.47). From a maximum knowledge score of 18 points, the median scores of males and females were 4 points (SD=2.346, range 0-13) and 4 points (SD=2.329, range 0-11) respectively. Better knowledge scores were associated with governorate, higher educational level, older age, higher income, having a chronic disease, having a family history of CRC, previously knowing someone who had CRC and their doctor's knowledge about their family history of CRC. Conclusions: There is a low level of knowledge about CRC and underestimation of risk among the study participants. This underlines the need for public health interventions to create awareness about the illness. It also calls for further research to assess the knowledge and perceptions about CRC early detection examinations in Jordan.

Survival Rates of Cervical Cancer Patients in Malaysia

  • Muhamad, Nor Asiah;Kamaluddin, Muhammad Amir;Adon, Mohd Yusoff;Noh, Mohamed Asyraf;Bakhtiar, Mohammed Faizal;Tamim, Nor Saleha Ibrahim;Mahmud, Siti Haniza;Aris, Tahir
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권7호
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    • pp.3067-3072
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    • 2015
  • Cervical cancer is the most common malignant cancer of the female reproductive organs worldwide. Currently, cervical cancer can be prevented by vaccination and detected at an early stage via various screening methods. Malaysia, as a developing country faces a heavy disease burden of cervical cancer as it is the second most common cancer among Malaysian women. This population based study was carried out to fulfil the primary aim of determining the survival rates of Malaysian women with cervical cancer and associated factors. Data were obtained from two different sources namely, the Malaysian National Cancer Registry (MNCR) and National Health Informatics Centre (NHIC) from 1st January 2000 to 31st December 2005. Kaplan Meier analyses were conducted to identify the overall survival rates and median survival time. Differences in survival among different ethnic and age group were compared using the log-rank test. A total of 5,859 patients were included. The median survival time for cervical cancer in this study was 65.8 months and the 5-year survival rate was 71.1%. The overall observed survival rates at 1, 3 and 5 years were 94.1%, 79.3% and 71.1% respectively. The log-rank test finding also showed that there were significant differences in the 5-year survival rate among different ethnic groups. Malays had the lowest survival rate of 59.2% followed by Indians (69.5%) and Chinese (73.8%). The overall 5-year survival rate among patients with cervical cancer in Malaysia is relatively good. Age and ethnic groups remain as significant determining factors for cervical cancer survival rate.