• Title/Summary/Keyword: common factors

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Predictive Factors for Recurrence after Burr-Hole Craniostomy of Chronic Subdural Hematoma

  • Kim, Sang Uk;Lee, Dong Hoon;Kim, Young Il;Yang, Seung Ho;Sung, Jae Hoon;Cho, Chul Bum
    • Journal of Korean Neurosurgical Society
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    • v.60 no.6
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    • pp.701-709
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    • 2017
  • Objective : Chronic subdural hematoma is a common and relatively benign disease. However, recurrence is common after surgical treatment, and the recurrence rate varies from 5% to 33%. The aim of this study was to investigate the predictive factors for recurrence of chronic subdural hematoma. Methods : We analyzed data from 248 patients with chronic subdural hematoma who were treated by burr-hole craniostomy with a closed drainage system for hematoma evacuation in this five-year retrospective study. Results : Thirty-one (12.6%) patients underwent re-operation for recurrence of chronic subdural hematoma. Univariate analysis revealed that anticoagulation (p=0.0279), headache (p=0.0323), and preoperative midline shifting (p=0.0321) showed significant differences with respect to recurrent chronic subdural hematoma. We performed a multivariate logistic regression analysis and found that diabetes mellitus (odds ratio [OR], 2.618; 95% confidence interval [CI], 1.0899-6.2898; p=0.0314), anticoagulation (OR, 6.739; 95% CI, 1.1287-40.2369; p=0.0364), headache (OR, 2.951; 95% CI, 1.1464-7.5964; p=0.0249), and preoperative midline shifting (OR, 1.0838; 95% CI, 1.0040-1.1699; p=0.0391) were independent predictive factors for recurrence of chronic subdural hematoma. Conclusion : We showed that diabetes mellitus, anticoagulation, headache, and preoperative midline shifting were independent predictors of recurrence of chronic subdural hematoma.

Prevalence and Risk Assessment of Cervical Cancer Screening by Papanicolaou Smear and Visual Inspection with Acetic Acid for Pregnant Women at a Thai Provincial Hospital

  • Lertcharernrit, Jiraporn;Sananpanichkul, Panya;Suknikhom, Wineeya;Bhamarapravatana, Kornkarn;Suwannarurk, Komsun;Leaungsomnapa, Yosapon
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.8
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    • pp.4163-4167
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    • 2016
  • Background: Cervical cancer is the second most common in Thailand, but the mortality rate may be rising yearly. It is a cancer that can be prevented by early screening for precancerous lesions, several methods being available. Objective: To identify the prevalence of abnormal Papanicolaou (Pap) smears and lesions with visual inspection with acetic acid (VIA) in pregnant women and assess risk factors for this group. Materials and Methods: This prospective study was performed at Prapokklao Hospital, Thailand during April-July 2016. All pregnant women of gestational age between 12-36 weeks who attended an antenatal clinic were recruited. All participants were screened for cervical cancer by Pap smear and VIA. If results of one or both were abnormal, colposcopic examination was evaluated by gynecologic oncologist. Results: A total of 414 pregnant women were recruited. Prevalence of abnormal Pap smear and VIA were 6.0 and 6.7 percent, respectively. The most common abnormal Pap smear was low grade intraepithelial lesion (LSIL, 44%). Factors associated with abnormal Pap smear in pregnant women were low BMI, multiple partners and being a government officer. In pregnancy, Pap smear had higher sensitivity and specificity than VIA for detection of precancerous cervical lesion. Patients with young coitarche or more than 25 years of active sexual activity were high risk groups. Conclusions: Prevalence of abnormal Pap smear and VIA in pregnant women was 6.0 and 6.7 percent, respectively. Factors associated with abnormal Pap smear were coitarche, years of sexual activity, low BMI, multiple partners and being a government officer.

Correlation Analysis in Information Security Checklist Based on Knowledge Network (지식 네트워크에 근거한 정보보호 점검기준 관계분석)

  • Jin, Chang Young;Kim, Ae Chan;Lim, Jong In
    • The Journal of Society for e-Business Studies
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    • v.19 no.2
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    • pp.109-124
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    • 2014
  • As the emerged importance and awareness for information security, It is being implemented by each industrial sector to protect information assets. In this paper, we analyze the information security checklists or security ratings criteria to derive similarity and difference in context which used to knowledge network analysis method. The analyzed results of all checklists (ISMS, PIMS, 'FSS', 'FISS', 'G') are as follows : First, It is common factors that the protection of information systems and information assets, incident response, operations management. Second, It deals with relatively important factors that IT management, the adequacy of audit activities in the financial IT sector including common factors. Third, the criteria of ISMS contains the majority of the contents among PIMS, 'FSS', 'FISS'and 'G'.

Prognostic Factors and Survival in Acute Myeloid Leukemia Cases: a Report from the Northeast of Iran

  • Allahyari, Abolghasem;Tajeri, Tarane;Sadeghi, Masoud
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1547-1551
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    • 2016
  • Background: Acute myeloid leukemia (AML) is a clonal hematopoietic disorder resulting from genetic alterations in normal hematopoietic stem cells. The aim of this study was to evaluate prognostic factors and survival of AML patients in the Northeast of Iran. Materials and Methods: This retrospective study covered 96 patients with AML referred to Emam Reza Hospital, Mashhad city, Iran, from 2009 to 2015. Age, sex, blood group, type of AML, fever, consumption of amphotericin B, cytogenetic forms and survival were analyzed. Also, WBC, hemoglobin and platelet levels were checked. Mean follow-up was 30.5 months (60.4% mortality). Survival was plotted by GraphPad Prism 5 with Log-rank test. Results: The mean age for all AML patients at diagnosis was 40.4 years (range, 17-77 years). Some 42.7% patients were aged <35 years and 40.6% were male. In all patients, 76% had fever and 50% consumed amphotericin. T(15;17)(q22;q21) had the most prevalence (37.7%) compared to other forms. Out of 92 patients, O+(30.4%) was the most common blood group and AML-M5 (28.3%) the most common subtype. There was a significant difference in survival based on WBC and consumption of amphotericin B (P<0.05). Conclusions: WBC level, fever and consumption of amphotericin B proved to be factors for survival of AML patients. The mean age for patients in Iran is lower than other areas in the World and also survival in this study was higher than in other studies.

Climate Change and Expansion of Squid Catches in Korea (한국에서의 기후변화와 오징어 어획의 확장)

  • Kim, Jong-Gyu;Kim, Joong-Soon
    • Journal of Environmental Health Sciences
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    • v.43 no.6
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    • pp.516-524
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    • 2017
  • Objectives: The annual catch of the common squid Todarodes pacificus in Korean coastal waters has gradually increased since the late 1980s. We investigated the long-term effects of climate variability on the variation in catches of the squid in the offshore fisheries of Korea. Methods: Moving average method, correlation analysis, and regression analysis were used to determine the relationship between the environmental factors and fluctuation in the catch of the squid during the past 30 years (1981- 2010). A ten-year moving average was calculated and used for each variable. Results: Squid catches in Korean coastal waters increased over time, and there were significant variations within every ten years (p < 0.001). Air temperature, atmospheric pressure, and wind grade among the meteorological factors, alongside sea surface temperature (SST) and concentrations of phosphate phosphorous, and nitrite/nitrate nitrogen in the sea water increased and were positively related with the catch size of squid (p < 0.001). However, salinity decreased and was negatively related with the catch size (p < 0.001). The increase in air temperature and SST was almost parallel, although there was a time lag between the two factors. Conclusion: These results suggest that there is a causal association between climate change and squid populations. Climate change, especially ocean warming, appears to have been largely favorable for squid range expansion into Korean seas. Although the expansion may be helpful for the human food supply, the safety of the squid caught should be monitored since the concentrations of phosphorous and nitrogen in the sea water increased, which indicates that Korean seas have grown gradually more polluted.

Descriptive Study on Selected Risk Factors and Histopathology of Breast Carcinoma in a Tertiary Care Centre in Kerala, India with Special Reference to Women Under 40 Years Old

  • Varughese, Ashley Ann;Poothiode, Usha;Manjula, V.D.
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.181-184
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    • 2015
  • Background: Breast cancer is the most common female cancer in Kerala, South India, with the incidence increasing in the past two decades, also in young women. However, there are limited data regarding the burden of disease, its epidemiology and histopathological characteristics in the state. Materials and Methods: This desciptive study covered 303 breast cancers evaluated during the period of December 2011 to August 2013 in the Department of Pathology, Government Medical College, Kottayam.The patients were also interviewed regarding selected risk factors. Results: The majority of the cases were 41-60 years of age with a mean at presentation of 53 years. Infiltrating ductal carcinoma was the most common subtype, followed by pure mucinous carcinoma and then lobular carcinoma. Of the cases, 6.6% were nullipara and 52.8% had fewer than or equal to 2 children. Median age at first child birth was 23 years (national value-19.8 years). A significant proportion (15%) had family history of breast cancer. Some 13.5%(41 cases) comprised the young breast cancer group (${\leq}40$years) with a mean age at first child birth in them was 27.4 years, 5 being nullipara and 6 having a positive family history. Conclusions: Breast cancer awareness, better availability of screening techniques and identification and targeting high risk groups all help to tackle the increasing load of breast carcinoma. A good proportion of cases comprised the young breast cancer group (under 40). Younger women should thus also be educated about breast carcinoma-risk factors, symptoms and diagnostic techniques to help in early detection and effective approach esto treatment.

Factors Affecting Cervical Cancer Screening Uptake by Hmong Hilltribe Women in Thailand

  • Wongwatcharanukul, Laead;Promthet, Supannee;Bradshaw, Peter;Jirapornkul, Chananya;Tungsrithong, Naowarat
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3753-3756
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    • 2014
  • Background: Cervical cancer is relatively common in Thai women, but the proportion of females receiving Pap smear screening is still low. Objective: The purpose of this cross-sectional study was to study factors related to cervical cancer screening uptake by Hmong hilltribe women in Lomkao District, Phetchabun Province. Materials and Methods: Interview data were collected from 547 of these women aged 30-60 years living in the study area and analyzed using multiple logistic regression. Results: The results showed that 64.9% of the study sample had received screening, and that 47.2% had attended due to a cervical screening campaign. The most common reason given for not receiving screening was lack of time (21.4%). The factors found to be positively associated with uptake (p value <0.05) were as follows: number of years of school attendance (OR=1.56, 95%CI:1.02-2.38), animistic religious beliefs (OR=0.55, 95%CI:0.33-0.91), a previous pregnancy (OR=6.20, 95%CI:1.36-28.35), receipt of information about cervical cancer screening (OR=2.25, 95%CI:1.35-3.76), and perceived risk of developing cervical cancer (OR=1.83, 95%CI:1.25-2.67). Conclusions: To promote the uptake of cervical screening, Hmong hilltribe women need to know more about cervical cancer and cervical cancer screening, and access to screening services should be provided in conjunction with existing everyday services, such as family planning and routine blood pressure monitoring or diabetes services.

A Case Study on Determinants of e-SCM Performances (e-SCM의 성과에 영향을 미치는 요인에 관한 사례 연구)

  • Kim, Do-Heon;Kim, Sang-Deok
    • Journal of Distribution Science
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    • v.6 no.2
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    • pp.21-39
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    • 2008
  • This paper is a case study on determinants of e-SCM performances. It suggested effective factors related with e-SCM performances for common feature, and point of difference between case firms. So the paper investigated former literature. Then it derived determinants on e-SCM performances. The authors found that establishment of e-SCM project team, mind change of top management, sharing of information, establishment of exact demand and supply plan, the best use of information technology, scale of organization, and collaboration of between firms are key success factors of e-SCM. Case company were three companies. The paper chose SONY, and Samsung Electronics among electronic companies, and HAITAI among confectionary companies. It analyze three companies about common feature, and point of difference, regarding seven effective factors as mentioned above.

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Evaluation of Environmental Risk Factors for Prostate Cancer in a Population of Iranian Patients

  • Pouresmaeili, Farkhondeh;Hosseini, S. Jalil;Farzaneh, Farah;Karimpour, Arezoo;Azargashb, Eznollah;Yaghoobi, Mohammad;Kamarehei, Maryam
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.24
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    • pp.10603-10605
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    • 2015
  • Background: The Prostate cancer is the 2nd most common cancer worldwide for males, and the 5th most common cancer overall, with an estimated 900,000 new cases diagnosed in 2008 (14% of the total in males and 7% of the total overall) aim of this study was to assess some of the most proposed environmental factors influencing the incidence of prostate cancer among Iranian men. Smoking, opioids, occupation and living location were considered as studied risk factors of the prostate cancer in this research. Material and methods: Two groups of affected men with prostate cancer and controls aged 50-75 years referred to medical clinics were subjects in this case-control study. Living and working place, smoking and drug consuming habits were assessed for any associations with prostate cancer. Results: The largest number, of patients, in order, belonged to Tehran, provincial capitals, major industrial cities, small towns and villages, respectively. The disease showed links with smoking and drugs with a significant difference between controls and patients (P value <0.0001). Conclusions: Our recent evidence duplicates previously done researches confirming the serious adverse effects of smoking and drugs on the prostate cancer occurrence in Iranian men. Living place bearings some hazardous behaviors which increases the rate of diseases as well as advanced chance for associated cancers like prostate.

Luteolin Induces Apoptosis via Mitochondrial Pathway and Inhibits Invasion and Migration of Oral Squamous Cell Carcinoma by Suppressing Epithelial-Mesenchymal Transition Induced Transcription Factors

  • Park, Bong-Soo;Kil, Jong-Jin;Kang, Hae-Mi;Yu, Su-Bin;Park, Dan-Bi;Park, Jin-A;Kim, In-Ryoung
    • International Journal of Oral Biology
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    • v.43 no.2
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    • pp.69-76
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    • 2018
  • Oral squamous cell carcinoma (OSCC) is the most common type of oral malignancy. Numerous therapies have been proposed for its cure. Research is continually being conducted to develop new forms of treatment as current therapies are associated with numerous side-effects. Luteolin, a common dietary flavonoid, has been demonstrated to possess strong anti-cancer activity against various human cancer cell lines. Nevertheless, research into luteolin-based anticancer activity against oral cancer remains scarce. Thus, the objective of this study was to assess the effect of luteolin as an anti-cancer agent. After treatment with luteolin, Ca9-22 and CAL-27 oral cancer cells showed condensed nuclei and enhanced apoptotic rate with evidence of mitochondria-mediated apoptosis. Epithelialmesenchymal transition (EMT) is closely related to tumor migration and invasion. Luteolin suppressed cancer cell invasion and migration in the current study. Elevated expression of E-cadherin, an adherens junction protein, was evident in both cell lines after luteolin treatment. Luteolin also significantly inhibited transcription factors (i.e., N-cadherin, Slug, Snail, Twist, and ZEB-1) that regulated expression of tumor suppressors such as E-cadherin based on Western blot analysis and quantitative PCR. Thus, luteolin could induce mitochondrial apoptosis and inhibit cancer cell invasion and migration by suppressing EMT-induced transcription factors.