• Title/Summary/Keyword: common cause of disease

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A Case of Orthostatic Proteinuria Progressed to Persistent Proteinuria Associated with Renal Pathology

  • Kim, Yoo-Jin;Cho, Byoung-Soo;Ha, Tae Sun
    • Childhood Kidney Diseases
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    • v.21 no.2
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    • pp.152-155
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    • 2017
  • Orthostatic or postural proteinuria is the most common cause of asymptomatic proteinuria in children. As orthostatic proteinuria (OP) is a benign disease with relatively good prognosis, it has no specific management, and patients only need to be observed. However, if OP shows a persistently high level of proteinuria, in theory, glomerular changes can occur. An 11-year-old girl was referred to the hospital due to asymptomatic proteinuria and was diagnosed as having OP based on the results of clinical and laboratory examinations, urinalysis, and protein/creatinine (TP/Cr) ratio at both supine and erect positions. During follow-up observation, the 24-hour TP/Cr ratio was persistently higher than 1.5 mg/mg for 2 years. We performed renal biopsy, which showed mesangial proliferative glomerular lesions with focal effacement of the podocyte foot processes, but without immune depositions. OP can be accompanied by glomerular lesions if moderate to severe proteinuria persists.

FPGA Implementation of an Artificial Intelligence Signal Recognition System

  • Rana, Amrita;Kim, Kyung Ki
    • Journal of Sensor Science and Technology
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    • v.31 no.1
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    • pp.16-23
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    • 2022
  • Cardiac disease is the most common cause of death worldwide. Therefore, detection and classification of electrocardiogram (ECG) signals are crucial to extend life expectancy. In this study, we aimed to implement an artificial intelligence signal recognition system in field programmable gate array (FPGA), which can recognize patterns of bio-signals such as ECG in edge devices that require batteries. Despite the increment in classification accuracy, deep learning models require exorbitant computational resources and power, which makes the mapping of deep neural networks slow and implementation on wearable devices challenging. To overcome these limitations, spiking neural networks (SNNs) have been applied. SNNs are biologically inspired, event-driven neural networks that compute and transfer information using discrete spikes, which require fewer operations and less complex hardware resources. Thus, they are more energy-efficient compared to other artificial neural networks algorithms.

Studies on the RBC Alloimmunization after Blood Transfusions

  • Kim Jae-Woo;Kim We-Jong
    • Biomedical Science Letters
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    • v.12 no.1
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    • pp.35-42
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    • 2006
  • Alloimmunization to red blood cell (RBC) antigens may cause a delayed hemolytic transfusion reactions (DHTR) and a delayed serologic transfusion reactions (DSTR). In the present study, the frequency of alloimmunization and its clinical significance were evaluated. Also, transfusions were correlated with antibody formation. Alloimmunization rate was 0.63%. Alloimmunization rate in multiple transfused patients was 24.5%. The most common clinically significant alloantibodies of alloimmunized patients were found to be Rh antibodies (52.6%). Nine patients out of 38 (23.7%) became undetectable after the first detection. To be positive at antibody screening test after RBC transfusion was mean transfused numbers: 3.7 units, mean transfused periods: 56 days, mean transfused frequencies: 1.7 times. The results from antibody specificity and RBC transfusions were comparatively analyzed and it shows that Rh system antibodies were longer than other antibodies (P<0.05). In case of disease group, malignant diseases was longer than other diseases (P<0.05). In order to prevent the formation of RBC alloimmunization, irregular antibody screening tests were performed at propriety intervals in multiple transfused patients.

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Two Cases of Cold Urticaria (한냉두드러기 환자 치험 2예)

  • Kim, Jung-Ho;Chae, Byeong-Yun
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.6 no.1
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    • pp.185-189
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    • 1993
  • Urticaria is a common disease and a well known reaction pattern of the skin charaterized by erythema or wheals and edema, that is the results of various cause. Cold urticaria has symptom on condition that patient feeles cold or touches ice and cold water. These symptoms have a tendency to be aggravated in the winter. We report two cases of cold urticaria. The patients are 38-year-old woman and 30-year-old woman with two years and four years history of recurrent urticaria. The patients showed cold urticaria We have experienced good improventment to be treated with acupuncture and herbal medicine by the Oriental Medicines.

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Clinical Study of Infectious Mononucleosis (전염성 단핵구증의 임상적 고찰)

  • 이형석;이승환;권순욱;김경래;허영돈
    • Korean Journal of Bronchoesophagology
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    • v.5 no.1
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    • pp.22-29
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    • 1999
  • Background: Infectious mononucleosis is a disease precipitated by Epstein-Barr virus(EBV) in mostly children, some seronegative adolescents and young adults comprising clinical symptoms such as fever, lymphadenopathy, and pharyngitis as well as laboratory findings such as hetero-phil antibodies and atypical lymphocytosis. It is confirmed by serologic test for EBV. Materials and Methods: A retrospective evaluation of 26 patients who diagnosed with infectious mononucleosis was peformed through the analysis of typical symptom, sign and laboratory findings. Results : Infectious mononucleosis occurs mostly at 3 to 10 years (74.9%), common symptoms and signs are fever, cervical lymphadenopathy, tonsillar enlargement and exudate. Positive ratio of atypical Lymphocyte(>10%) and hetrophil antibodies are 61.5%, 35.2% respectively, it is less diagnostic. EBV-viral capsid antigen(VCA) IgM are positive in all cases, so it is most diagnostic findings. Conclusion: Infectious mononucleosis should be considered as a cause of cervical lymphadenopathy and pharyngotonsillitis in children and young adults, the assessment of EBV-VCA IgM is necessary for the diagnosis.

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Clinical importance of TMJ Osteoarthritis in Dental Practice (임상가를 위한 특집 3 - 치과진료에서 악관절 골관절염의 중요성)

  • Tae, Ilho;Song, Yunheon;Kim, Youn Joong
    • The Journal of the Korean dental association
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    • v.51 no.2
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    • pp.92-98
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    • 2013
  • Osteoarthritis is one of the most common degenerative disease in the temporomandibular joints(TMJ). Structural changes in the osseous structure is associated with destructive changes such as erosion, flattening and other bony changes. Destructive degenerative changes quite often cause shortening of the condyles which eventually produces the changes in the occulsion and the facial profile which require orthorgnathic surgery and/or orthodontic treatment by the dental professional. The dentists need to understand the nature and the pathophysiology of the osteoarthritis in the TMJ for the better dental treatment, especially in orthodontic and prosthodontic treatment. The possibility of serious complication can not be avoided after any dental treatment is given to the patient if osteoarthritic changes in the TMJ is under progression as undiscovered.

Thyroid dysfunction and subfertility

  • Cho, Moon Kyoung
    • Clinical and Experimental Reproductive Medicine
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    • v.42 no.4
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    • pp.131-135
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    • 2015
  • The thyroid hormones act on nearly every cell in the body. Moreover, the thyroid gland continuously interacts with the ovaries, and the thyroid hormones are involved in almost all phases of reproduction. Thyroid dysfunctions are relatively common among women of reproductive age, and can affect fertility in various ways, resulting in anovulatory cycles, high prolactin levels, and sex hormone imbalances. Undiagnosed and untreated thyroid disease can be a cause of subfertility. Subclinical hypothyroidism (SCH), also known as mild thyroid failure, is diagnosed when peripheral thyroid hormone levels are within the normal reference laboratory range, but serum thyroid-stimulating hormone levels are mildly elevated. Thyroid autoimmunity (TAI) is characterized by the presence of anti-thyroid antibodies, which include anti-thyroperoxidase and anti-thyroglobulin antibodies. SCH and TAI may remain latent, asymptomatic, or even undiagnosed for an extended period. It has also been demonstrated that controlled ovarian hyperstimulation has a significant impact on thyroid function, particularly in women with TAI. In the current review, we describe the interactions between thyroid dysfunctions and subfertility, as well as the proper work-up and management of thyroid dysfunctions in subfertile women.

Rotavirus Vaccines (로타바이러스 백신)

  • Koh, Hong
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.12 no.sup1
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    • pp.72-76
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    • 2009
  • Rotavirus infection is the leading cause of severe diarrhea disease in infants and young children worldwide. Rotavirus infects every child at least once by her/his $5^{th}$ birthday. It has been known that single episode of rotavirus infection can protect or alleviate subsequent illness caused by both homotypic and heterotypic rotaviruses. There are two currently licensed rotavirus vaccines. One is human-bovine rotavirus reassortant pentavalent vaccine ($RotaTeq^{TM}$), which contains five reassortant rotavirus (expressing protein G1, G2, G3, G4 and P[8]) and was licensed in Korea for use among infants in 2007. Another is live-attenuated human rotavirus vaccine ($Rotarix^{TM}$) derived from 89-12 strain which represents the most common of the human rotavirus VP7(G1) and VP4(P[8]) antigens. $Rotarix^{TM}$ was licensed in Korea in 2008. Both live oral rotavirus vaccines are efficacious in preventing severe rotavirus gastroenteritis.

Death due to Aspergillus Tracheobronchitis: An Autopsy Case (아스페르길루스 기관기관지염에 의한 사망: 부검 1예)

  • You, Tack Kune;Choi, Byung Ha;Lee, Bong Woo;Choi, Young Shik
    • The Korean Journal of Legal Medicine
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    • v.42 no.4
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    • pp.164-167
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    • 2018
  • Aspergillus infection is the most common cause of death due to fungi in immunocompromised hosts. Aspergillus tracheobronchitis is an uncommon but severe form of invasive pulmonary aspergillosis, which is limited entirely or mainly to the tracheobronchial tree and can often be life-threatening. We report a case of a 54-year-old man who died from Aspergillus tracheobronchitis without an underlying disease. Autopsy revealed an extensive yellowish plaque adhering to the trachea and bronchial wall. The microscopic examination of the trachea and bronchus revealed septate branching hyphae of Aspergillus.

Surgical experience of Takayasu`s arteritis: one case report (Takayasu 동맥염의 수술치험 1례 보)

  • Im, Jin-Su;Choe, Hyeong-Ho;Jang, Jeong-Su
    • Journal of Chest Surgery
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    • v.17 no.4
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    • pp.709-714
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    • 1984
  • The Takayasus arteritis is the obstructive disease in the principal branches arising from the aortic arch, and it can cause circulatory disturbances in the head or arms. We have experienced a case of complete obstruction of the left subclavian artery, the patient was undergone surgical repair with Knitted-Dacron patch graft between the left common carotid artery and the left subclavian artery. After operation, there were no symptoms except hypertension, and also no postoperative complications were seen. In the postoperative aortogram, the patency of the graft was good. The postoperative course was eventful and he has been in good conditions up to now so far.

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