• Proceedings of the Korean Society of Life Science Conference
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• 2006.09a
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• pp.48.1-48.1
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• 2006

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.26 no.5
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• pp.277-283
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• 2023

Purpose: Cow's milk protein allergy (CMPA) is a common condition in infants, but little is known about healthcare providers' clinical experience treating infants with CMPA. To address this gap, we analyzed prospectively collected data from healthcare providers (HCPs) who treated infants under six months old with suspected CMPA using hypoallergenic formulas. The study focused on a commercial extensively hydrolyzed formula containing Lactobacillus rhamnosus GG (ATCC53103) (eHF-LGG) or a commercial amino acid formula (AAF). Methods: In this secondary analysis of prospectively collected survey data, 52 HCPs treated 329 infants under six months old with suspected CMPA using hypoallergenic formulas. A series of two de-identified surveys per patient were collected by HCPs to assess short-term symptom relief in the patients and HCP's satisfaction with the management strategies. The initial survey was completed at the initiation of treatment of CMPA, and the second survey was completed at a follow-up visit. Results: The majority of HCPs (87%) in the study were general pediatricians, and most saw 2 to 10 CMPA patients weekly. Results showed that clinicians reported satisfaction with treatment in 95% of patients in the EHF cohort and 97% of patients in the AAF cohort and achieved expected clinical results in 93% and 97% of patients using eHF and AAF, respectively. Furthermore, few patients were switched from the hypoallergenic formula once initiated. Conclusion: The study provides new insights into HCP perspectives on treating infants with CMPA and supports using hypoallergenic formulas to manage this condition. However, additional prospective controlled studies are needed to confirm these initial findings.

• Journal of Nutrition and Health
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• v.34 no.1
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• pp.23-29
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• 2001

This study was conducted to investigate the concentrations and infants intake of sodium and potassium from human milk during the first 5 months of lactation. The sodium concentrations of the milk during the lactation appeared 21.1, 18.1, 15.9, 12.4, 10.6 and 11.4 mg/100g at 0.5, 1, 2, 3, 4, and 5 months of lactation respectively. The potassium concentrations of the milk 48.5, 43.3, 40.8, 39.9, 40.5 and 38.5 respectively, Na/K ratio of the milk were 0.76, 0.75, 0.70, 0.56, 0.46 and 0.53(mEqu\\mEq). Sodium intakes of breast-fed infants were 106.9, 108.4, 90.6, 82.5 and 95.6mg/day during the lactation. Potassium intakes of the infants were 255.7, 276.0, 289.7, 294.6, 320.3 and 318.3mg/day. Sodium and potassium concentrations in infant formula averaged 23.62 and 67.61 mg/100g which was 1.90 and 1.69 times as those of breast milk at 3 month of lactation. Commercial whole milks had 39.53 and 135.22mg/100g of sodium and potassium respectively which was 3.19 and 3.39 times as those of the milk. From this study, reevaluation of sodium and potassium intakes if breast-fel infants was merited and the regulation of that minerals in infant formula is need to lower the renal solute load of formula-fed infants.(Korean J Nutrition 34(1):23-29, 2001)

• Korean Journal of Community Nutrition
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• v.1 no.3
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• pp.335-345
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• 1996

The solids(supplementary food) consumption of 200 healthy infants aged from 4 to 6 months have been measured. Five groups were assigned to different feeding patterns. Breastfed group(BF, n=38), formula-fed group(FF, n=102) and mixed-fed group(MF, n=14) were fed breast milk, formula and mixed(breast mile+formula) from birth until 6 months of age respectively. Convert 1 group(C1F, n=14) and convert 2 group(C2F, n=32) were fed breast milk and mixed milk at 2 months of age respectively and were switched to formula thereafter. All infants received solids form 4 months of age. The energy intake from solids at 4 and 6 months averaged 59.1 and 110.3㎉/d among BF groups vs 151.9 and 239.3㎉/d among FF groups respectively. Intakes of protein, calcium and iron were 38-46$\%$, 34-44% and 25-37$\%$ higher in the FF than in the Bf group during the first 6 months. However, no significant differences were found in the intakes of energy and nutrient intakes from solids in all 4 groups excluding BF group(39$\%$). Although BF infant's nutrient intakes from solids were lower than other group's intakes, they intaked evenly solids from various food groups. As the age of infant had increased, the energy intake ratio from solids was cereals and dairy products was increased whereas energy intake ratio from meats, eggs, fruits and vegetables was decreased. TSC4, TSC6(the frequency score for the kinds of weaning food taken) showed no significant difference among 5 feeding groups but CIF-and C2F group's scores tended to be high. Consequently, these results suggest that BF group's solid intake pattern is more desirable and that Korean lactating Mother's dependence on commercial weaning food is too high.

• Human Ecology Research
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• v.51 no.4
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• pp.383-393
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• 2013

The purpose of this study is to investigate the infant feeding and weaning practices in multicultural families. We surveyed 159 married female immigrants in Jeonbuk province from April 2010 to April 2011. They are from Vietnam (49.7%), China (25.8%), Cambodia (8.8%), Japan (8.2%), and the Philippines (7.5%). The average rate of colostrum feeding of all the subjects was 91% and there were significant differences between nationalities (p<.05), family types (p<.01), and delivery methods (p<.001). 41.5% of those answered did breast feeding, while 49.1% combined breast and bottle feeding, and 9.4% did bottle feeding only. The reason for bottle feeding is either because they are unable to produce enough breast milk or because they think the formula is better than breast milk. Average period of breast feeding was 10.3 months. There were significant differences of breast feeding duration between maternal age (p<.05) and economic level (p<.001). The mean onset time of weaning was 7.8 months, and there were significant differences between nationalities (p<.05), family types (p<.05), and feeding methods (p<.05). There was no significant difference in methods of supplementary food preparation between nationalities, family types, jobs, and education levels. The mean onset time of commercial milk was 12.8 months, and there were significant differences between nationalities (p<.05), the duration of marriages (p<.05), education levels (p<.05) and feeding methods (p<.001).

• The Journal of Pediatrics of Korean Medicine
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• v.13 no.2
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• pp.1-39
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• 1999

A infancy is the period in that growth and development of man are the most fast and neutrial requirement is the most big on his life. The insufficient neutrition of this period can have bad effect uppon man's whole life health not only physically but also pscychogenically and emotionally. Therefore a proper feeding at a proper time is very important to form the good food behavior and emotional development. The rate of using the commercial weaning food in Korea has gradually increased since 1970 and expected to be more increasing in future. In this paper, I investigate the general weaning status, stneutrial component and material content of infant weaning foods marketing in Korea at present. The material for this study have been collected in the exposition of products and data from manufacturing companies and etc. The conclusion is following. 1. The proper weaning period is from $4{\sim}6$ momth to 12 momth, but recently it is inclined to prolong. 2. In weaning methods, using a spoon is superior to using a bottle in food behavior and neutrial status. 3. The commercial weaning foods have two type, the powder type and formula type, but except gober's, all products marketing in Korea are the powder type and a sort of product is very simple. Therefore it is necessary to develp the more various kind of weaning foods, especially the formula type. 4. In the neutrial component, Son-Sik (flour of grain) cannot be up to international standards and the greater parts of weaning foods have too much suger over the standards.

• Food Science of Animal Resources
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• v.21 no.1
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• pp.56-63
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• 2001

In this study, three domestic and one foreign formulas for the infants up to 5 month old were examined to detect chemical changes such as pH, reactive sulfhydryl groups(RSH) content, 5-hydroxymethylfurfral(HMF) content, available lysine content, electrophoresis, and surface color caused by heat treatment for long term storage. In the SDS-polyacrylamide gel electrophoresis, A and B products showed similar pattern, while C product had a clearly distinguishable $\beta$-lacto-globulin band, but in casein, only D product showed a few strong casein band. RSH content, which indicate the extent of whey protein denaturation, ranged from 4.40 to 5.93 mmole/g protein. HMF content. which indicate the extent of Maillard reaction, ranged from 192 to 432 $\mu$mole/100g in formulas. B product showed the highest RSH and HMF content. Available lysine content ranged from 31 to 46 mg/g protein. Among them D product contain the highest available lysine content and others showed no significant difference. In conclusion, the domestic infant formulas showed higher RSH and HMF content than the foreign product and the available lysine content of the domestic products were lower than of the foreign product.

• Korean Journal of Agricultural Science
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• v.48 no.4
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• pp.771-786
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• 2021

This study was performed to investigate the contents of fat-soluble nutrients (tocopherols, retinol, carotenoids, fatty acids, and cholesterol) and phospholipids (PLs) in seven types (imported SPA, SPS, SFS, and SSI; and domestic MLM, MPM, and NIX) of commercial infant formulas (IFs). The contents of tocopherol and retinol activity equivalent (RAE) in the seven IFs were 1.42 - 3.86 mg α-TE·100 kcal^-1 and 64.90 - 144.95 ㎍ RAE·100 kcal^-1, respectively. The imported IFs contained high contents of lutein + zeaxanthin (29.68 - 32.49 ㎍·100 g^-1) and lycopene (71.80 - 93.28 ㎍·100 g^-1), while the domestic IFs did not contain lycopene. The contents of linoleic acid (C18:2) and α-linolenic acid (C18:3) in the seven IFs were also within the recommended ranges (C18:2, 300 - 1,400 mg·100 kcal^-1 and C18:3, over 50 mg·100 kcal^-1) of Ministry of Food and Drug Safety. The ratio of arachidonic acid (ARA, C20:4)/docosahexaenoic acid (DHA, C22:6) was 2.42 - 2.74 in the imported IFs and 0.96 - 1.08 in the domestic IFs. However, the DHA content of the domestic IFs (0.37 - 0.65 g·100 g^-1 fat%) was much higher than that of the imported IFs (0.16 - 0.18%). Total PL contents were 108.02 - 135.93 mg·100 kcal^-1 for the domestic IFs and 6.05 - 66.70 mg·100 kcal^-1 for the imported IFs. The main PLs of the domestic IFs were phosphatidyl choline (48.5 - 71.1% of total PLs), phosphatidyl ethanolamine (12.8 - 23.1%), phosphatidyl serine (7.0 - 11.6%), and sphingomyelin (4.3 - 21.5%).

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.6
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• pp.881-890
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• 2019

Objective: A study was conducted to develop non-dairy creamer analogs/mimics using egg white, egg yolk, soy protein and their combinations, and their nutrient content, shelf-life and flavor acceptability were compared. Methods: Spray dried egg white, egg yolk, and soy protein isolate were purchased from manufacturers and used for the formulae. Results: The protein contents of the non-dairy creamer analogs/mimics were about 8.5% as calculated. The amounts of oleic and linoleic acid content increased as the amount of yolk increased in the formula, but the increases of polyunsaturated fatty acids were <0.5% of total fat. Addition of egg yolk to the formula increased choline and lutein content in the products, but the amounts were <0.4 mg/g for choline and $4{\mu}g/g$ for lutein. The lutein in the products continued to decrease over the storage time, and only about 15% to 20% of the 0-month amounts were left after 3 months of storage. Although the thiobarbituric acid reactive substances values of the spray-dried non-dairy creamer analogs/mimics increased as storage time increased, the values were still low. Yellowness, darkness, and egg flavor/odor of the non-dairy creamer analogs/mimics increased as the amount of egg yolk in the formula increased. The overall acceptability of the non-dairy creamer analogs/mimics was closely related to the intensity of egg flavor/odor, but storage improved their overall acceptance because most of the off-odor volatiles disappeared during the storage. Water temperature was the most important parameter in dissolving spray-dried non-dairy creamer analogs/mimics, and $55^{\circ}C$ to $75^{\circ}C$ was the optimal water temperature conditions to dissolve them. Conclusion: Higher amounts of yolk and soy protein combinations in place of egg white reduced the cost of the products significantly and those products contained better and balanced nutrients than the commercial coffee creamers. However, off-flavor and solubility were two important issues in the products.

• Journal of Dairy Science and Biotechnology
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• v.39 no.3
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• pp.104-112
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• 2021

This study was conducted to evaluate the efficacy of commercial disinfectants at inactivating Enterobacter sakazakii (Cronobacter spp.) in water. Disinfectant I contained 6.15% sodium hypochlorite, and disinfectant II contained both 2.25% n-alkyl dimethylbenzyl ammonium chloride and 2.25% n-alkyl ethylbenzyl ammonium chloride. Disinfectant I was added to distilled water to obtain a range of residual chloride concentrations at 50 ppm intervals with a maximum of 1-1,000 ppm. Disinfectant II was prepared at concentrations ranging from 1-200 ppm with 5 ppm intervals. Exposure time for all solutions was 10 min. In total, 58 E. sakazakii (Cronobacter spp.) strains were tested in this study. Nine isolates were obtained from clinical samples, and 49 isolates were obtained from environmental samples. Seven strains (6 clinical and 1 environmental) were able to survive in 100 ppm disinfectant I, and a maximum of 5 ppm of disinfectant II. Fifty one strains (3 clinical and 48 environmental) were not killed in 10 ppm of disinfectant I and 1 ppm of disinfectant II in water. In conclusion, this study demonstrated that clinical E. sakazakii (Cronobacter spp.) strains displayed 5- to 10-fold higher resistance to disinfectants than environmental E. sakazakii (Cronobacter spp.) strains. Disinfectant II, containing quaternary ammonium compounds, was shown to be more potent in inactivating E. sakazakii (Cronobacter spp.) in water used to clean infant formula manufacturing equipment than disinfectant I.