• Food Science of Animal Resources
• /
• v.32 no.1
• /
• pp.1-5
• /
• 2012

The objective of this study was to examine the effects of a combined treatment regarding antimicrobial food ingredients and high pressure processing (HP) on the inactivation efficiency of Escherichia coli and Listeria monocytogenes inoculated into ground pork. Ethanol extracted from garlic, leeks, onions, and ginger powder was prepared. Half of the prepared powder was irradiated at 5 kGy to see the effect of pasteurization before addition. The prepared food ingredients were added into radiation-sterilized ground pork (1%, w/w), and inoculated with E. coli and L. monocytogenes. The samples were vacuum-packed and applied with HP at 0.1 (control), 300, 450, and 600 MPa. Microbial log reduction increased with the increase of pressure up to 600 MPa. With minor exceptions, overall efficiency of HP treatment with regards to inactivation of pathogens increased. Inoculated microorganisms showed approximately 7-8 Log reductions by 600 MPa, except for L. monocytogenes treated with garlic (5.7 Log reductions). The E. coli reduction in ground pork mixed with ethanol extracted garlic showed the highest efficiency (1.86) compared to leeks (1.25-1.31), onions (1.17-1.44), and ginger (1.50-1.82) when treated at an HP of 450 MPa. There was no evidence for the advantage of pasteurization concerning the food ingredients before addition of antimicrobial food ingredients and HP. Results demonstrate that the combination of antimicrobial food ingredients and HP treatment may help improve the efficiency of sterilization in meat systems.

• Journal of Information Processing Systems
• /
• v.15 no.6
• /
• pp.1472-1488
• /
• 2019

Critical elements in the China's Lunar Exploration reside in that the lunar rover travels over the surrounding undetermined environment and it conducts scientific exploration under the ground control via teleoperation system. Such an interplanetary transportation mission teleoperation system belongs to the ground application system in deep space mission, which performs terrain reconstruction, visual positioning, path planning, and rover motion control by receiving telemetry data. It plays a vital role in the whole lunar exploration operation and its so-called trustworthy evidence must be assessed before and during its implementation. Taking ISO standards and China's national military standards as trustworthy evidence source, the net assessment model and net assessment method of teleoperation system are established in this paper. The multi-dimensional net assessment model covering the life cycle of software is defined by extracting the trustworthy evidences from trustworthy evidence source. The qualitative decisions are converted to quantitative weights through the net assessment method (NAM) combined with fuzzy analytic hierarchy process (FAHP) and entropy weight method (EWM) to determine the weight of the evidence elements in the net assessment model. The paper employs the teleoperation system for interplanetary transportation as a case study. The experimental result drawn shows the validity and rationality of net assessment model and method. In the final part of this paper, the untrustworthy elements of the teleoperation system are discovered and an improvement scheme is established upon the "net result". The work completed in this paper has been applied in the development of the teleoperation system of China's Chang'e-3 (CE-3) "Jade Rabbit-1" and Chang'e-4 (CE-4) "Jade Rabbit-2" rover successfully. Besides, it will be implemented in China's Chang'e-5 (CE-5) mission in 2019. What's more, it will be promoted in the Mars exploration mission in 2020. Therefore it is valuable to the development process improvement of aerospace information system.

• Journal of Ginseng Research
• /
• v.36 no.2
• /
• pp.169-175
• /
• 2012

Ginseng has been used as a traditional medicine for treatment of many diseases and for general health maintenance in people of all ages. Ginseng is also used to ameliorate menopausal systems. We investigated the estrogenic activity of Korean red ginseng (KRG) in a transient transfection system, using estrogen receptor (ER) and estrogen-responsive luciferase plasmids in MCF-7 cells. The extract activated both ER${\alpha}$ and ER${\beta}$. KRG modulated the mRNA levels of estrogen-responsive genes such as pS2 and ESR1 and decreased the protein level of ER${\alpha}$. In order to examine in vivo estrogenic activity of KRG, sixteen female Sprague-Dawley rats separated into four groups were studied for nine weeks: non-ovariectomized (OVX) rats treated with olive oil, OVX rats treated with olive oil, OVX rats treated with 17-${\beta}$-estradiol (E2) in olive oil, and OVX rats treated with KRG extract in olive oil. The experiments were repeated for three times and the data of twelve rats were combined. Body weight of OVX rats was greater than that of sham-operated control rats and was decreased by E2 treatment. Uterine weight increased after E2 treatment compared to OVX rats. However, no difference in body or uterine weight was observed with KRG intake. KRG induced reductions in total cholesterol, low density lipoprotein cholesterol/total cholesterol, high density lipoprotein cholesterol/total cholesterol, and low density lipoprotein cholesterol/high density lipoprotein cholesterol, but not to the same degree as did E2 intake. These results show that KRG does contain estrogenic activity as manifested by in vitro study but the activity is not strong enough to elicit physiological responses.

• Journal of Acupuncture Research
• /
• v.23 no.2
• /
• pp.33-46
• /
• 2006

Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disease associated with aging in the human population. This disease is characterized by the extracellular deposition of beta-amyloid peptide $(A{\beta})$ in cerebral plaques. $A{\beta}$ is derived from the ${\beta}-amyloid$ precursor protein (APP) by the enzymes, ${\beta}-$ and ${\eta}o-secretase$. Compounds that ${\beta}-$ or ${\eta}o-secretase$ inhibit activity, can reduce the production of $A{\beta}$ peptides, and thus have therapeutic potential in the treatment of AD. Increasing body of evidence has been demonstrated that Bee Venom(BV) Acupuncture could compete with complex protein involving in multiple step of $NF-{\kappa}B$ activation and exert the anti-inflammatory potential of combined inhibition of the prostanoid and nitric oxide synthesis systems by inhibition of IKK and $NF-{\kappa}B$. In this study, I investigated possible effects of BV on memory dysfunction caused by lipopolysaccharide (LPS) and $A{\beta}$ through inhibition of secretases activities and $A{\beta}$ aggregation. I examined the improving effect of BV on the LPS (2.5 mg/Kg, i.p.)-induced memory dysfunction using passive avoidance response and water maze tests in the mice. BV (0.84, $1.67\;{\mu}g/ml$) reversed the LPS-induced memorial dysfunction in dose dependent manner. BV also dose-dependently attenuated LPS-induced ${\beta}$ and ${\eta}o-secretase$ activities in cerebral cortex and hippocampus of the mice brain. This study therefore suggests that BV acupuncture method may be useful for prevention of development or progression of AD.

• Journal of the Korean Institute of Telematics and Electronics C
• /
• v.35C no.9
• /
• pp.11-20
• /
• 1998

High-speed complex-number arithmetic units are essential to baseband signal processing of modern digital communication systems such as channel equalization, timing recovery, modulation and demodulation. In this paper, a new complex-number multiplication algorithm is proposed, which is based on redundant binary (RB) arithmetic combined with radix-4 Booth recoding scheme. The proposed algorithm reduces the number of partial product by one-half as compared with the conventional direct method using real-number multipliers and adders. It also leads to a highly parallel architecture and simplified circuit, resulting in high-speed operation and low power dissipation. To demonstrate the proposed algorithm, a prototype complex-number multiplier-accumulator (CMAC) core with 10-bit operands has been designed using 0.8-$\mu\textrm{m}$ N-Well CMOS technology. The designed CMAC core contains about 18,000 transistors on the area of about 1.60 ${\times}$ 1.93 $\textrm{mm}^2$. The functional and speed test results show that it can operate with 120-MHz clock at V$\sub$DD/=3.3-V, and its power consumption is given to about 63-mW.

• Journal of the Korean Chemical Society
• /
• v.9 no.4
• /
• pp.153-160
• /
• 1965

Ultraviolet spectrophotometric investigations have been carried out on the systems of benzene with iodine, bromine, chlorine and iodine monobromide in carbon tetrachloride. The results reveal the formation of one to one molecular complexes of the type, $C_6H_6{\cdot}X_2\;or\;C_6H_6{\cdot}IX$ (X denotes halogen atoms). The equilibrium constants obtained at $25^{\circ}$for the complex formation are 0.173, 0.137, 0.0643 and 0.341 $lmole^{-1}$ for $C_6H_6{\cdot}I_2,\;C_6H_6{\cdot}Br_2,\;C_6H_6{\cdot}Cl_2\;and\;C_6H_6{\cdot}IBr$, respectively. These results combined with those obtained by other workers indicate that the relative stabilities of the benzene complexes decrease in the order, $ICl > IBr > I_2 > Br_2 > Cl_2.$ This order may be measure of their relative acidities toward benzene, which is explained in terms of the relative polarizabilities of halogen molecules and the relative electronegativities of halogen atoms.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.40 no.4
• /
• pp.260-267
• /
• 2017

Quantum-inspired Genetic Algorithm (QGA) is a probabilistic search optimization method combined quantum computation and genetic algorithm. In QGA, the chromosomes are encoded by qubits and are updated by quantum rotation gates, which can achieve a genetic search. Asset-based weapon target assignment (WTA) problem can be described as an optimization problem in which the defenders assign the weapons to hostile targets in order to maximize the value of a group of surviving assets threatened by the targets. It has already been proven that the WTA problem is NP-complete. In this study, we propose a QGA and a hybrid-QGA to solve an asset-based WTA problem. In the proposed QGA, a set of probabilistic superposition of qubits are coded and collapsed into a target number. Q-gate updating strategy is also used for search guidance. The hybrid-QGA is generated by incorporating both the random search capability of QGA and the evolution capability of genetic algorithm (GA). To observe the performance of each algorithm, we construct three synthetic WTA problems and check how each algorithm works on them. Simulation results show that all of the algorithm have good quality of solutions. Since the difference among mean resulting value is within 2%, we run the nonparametric pairwise Wilcoxon rank sum test for testing the equality of the means among the results. The Wilcoxon test reveals that GA has better quality than the others. In contrast, the simulation results indicate that hybrid-QGA and QGA is much faster than GA for the production of the same number of generations.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.41 no.2
• /
• pp.84-94
• /
• 2018

In recent years, the diminishing of operation and maintenance cost using advanced maintenance technology is attracting many companies' attention. Especially, the heavy machinery industry regards it as a crucial problem since a failure of heavy machinery requires high cost and long downtime. To improve the current maintenance process, the heavy machinery industry tries to develop a methodology to predict failure in advance and to find its causes using usage data. A better analysis of failure causes requires more data so that various kinds of sensor are attached to machines and abundant amount of product usage data is collected through the sensor network. However, the systemic analysis of the collected product usage data is still in its infant stage. Many previous works have focused on failure occurrence as statistical data for reliability analysis. There have been less works to apply product usage data into root cause analysis of product failure. The product usage data collected while failures occur should be considered failure cause analysis. To do this, this study proposes a methodology to apply product usage data into failure cause analysis. The proposed methodology in this study is composed of several steps to transform product usage into failure causes. Various statistical analysis combined with product usage data such as multinomial logistic regression, T-test, and so on are used for the root cause analysis. The proposed methodology is applied to field data coming from operated locomotive and the analysis result shows its effectiveness.

• The KSFM Journal of Fluid Machinery
• /
• v.13 no.1
• /
• pp.9-16
• /
• 2010

In the power generation industry, various efforts are needed to cope with tightening regulation on carbon dioxide emission. Integrated gasification combined cycle (IGCC) is a relatively environmentally friendly power generation method using coal. Moreover, pre-combustion $CO_2$ capture is possible in the IGCC system. Therefore, much effort is being made to develop advanced IGCC systems. However, removal of $CO_2$ prior to the gas turbine may affect the system performance and operation because the fuel flow, which is supplied to the gas turbine, is reduced in comparison with normal IGCC plants. This study predicts, through a parametric analysis, system performances of both an IGCC plant using normal syngas and a plant with $CO_2$ capture. Performance characteristics are compared and influence of $CO_2$ capture is discussed. By removing $CO_2$ from the syngas, the heating value of the fuel increases, and thus the required fuel flow to the gas turbine is reduced. The resulting reduction in turbine flow lowers the compressor pressure ratio, which alleviates the compressor surge problem. The performance of the bottoming cycle is not influenced much.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.13 no.2
• /
• pp.176-187
• /
• 2002

The digital Audio Broadcasting (DAB) system adopts Coded OFDM(COFDM) for channel coding. The COFDM is a combined technique of multicarrier transmission(OFDM) and punctured convolutional coding with viterbi error correction. Because the channel coding is an important topic for OFDM systems, this paper proposes a new turbo coded OFDM system that replaces the existing RCPC codec by a turbo codec without modifying the puncturing procedure and puncturing vectors defined in the standard DAB system for compatibility. The performance of a new system is compared to that of the conventional system under the frequency selective Rician fading channel and the frequency selective Rayleigh fading channel in conjunction with DAB transmission mode I suitable for the terrestrial single frequency network(SFN) broadcasting. The standard system's performance was improved with the aid of turbo codec.