• Animal Bioscience
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• v.35 no.10
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• pp.1616-1627
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• 2022

Objective: This work was conducted to investigate the effects of oxidative stress on meat quality, mitochondrial function, calcium metabolism and ferroptosis of broilers. Methods: In this study, a total of 144 one-day-old male Ross 308 chicks were divided into 3 groups (control group, saline group, and hydrogen peroxide [H₂O₂] group) with 6 replicates of 8 broilers each. The study lasted for 42 d. The broilers in the saline and H₂O₂ groups were intraperitoneally injected with 0.75% saline and 10.0% H₂O₂ on the 16th and 37th day of the experimental period respectively, the injection volumes were 1.0 mL/kg of broiler body weight. On the 42nd day of the experimental period, two chicks were randomly selected from each cage, a total of thirty-six chicks were stunned by electric shock and slaughtered to collect breast muscle samples. Results: The H₂O₂ exposure reduced pH value, increased drip loss and shear force of breast meat (p<0.05), impaired the ultrastructure and function of mitochondria. The H₂O₂ exposure damaged the antioxidant system in mitochondria, excessive reactive oxygen species carbonylation modified calcium channels on mitochondria, which impaired the activities of key enzymes on calcium channel, resulted in the increased calcium concentration in cytoplasm and mitochondria (p<0.05). In addition, the H₂O₂ exposure increased the iron content and lipid peroxidation (p<0.05), which induced ferroptosis. Conclusion: Oxidative stress could impair meat quality by causing mitochondrial dysfunction, resulting in calcium metabolism disorder and ferroptosis.

• Proceedings of the Korea Information Assurance Society Conference
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• 2004.05a
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• pp.119-124
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• 2004

The service oriented architecture (SOA) is gaining more momentum with the advent of Web services on internet. A programmable and machine accessible Web is the vision of many, and might represent a step towards the semantic Web. However, security is a crucial requirement for the serious usage and adoption of the Web services technology. This paper proposes design goals for an distributed access control model for CPC(Collaborative Product Commerce). It then design a processor model for CPC components, along with web services standard and concept that can be used as a basis to design an access control processor independent of a particular CPC service implementation.

• Earthquakes and Structures
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• v.10 no.6
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• pp.1253-1272
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• 2016

For a nonlinear control system, there are many uncertainties, such as the structural model, controlled parameters and external loads. Although the significant progress has been achieved on the robust control of nonlinear systems through some researches on this issue, there are still some limitations, for instance, the complicated solving process, weak conservatism of system, involuted structures and high order of controllers. In this study, the computational structural mechanics and optimal control theory are adopted to address above problems. The induced norm is the eigenvalue problem in structural mechanics, i.e., the elastic stable Euler critical force or eigenfrequency of structural system. The segment mixed energy is introduced with a precise integration and an extended Wittrick-Williams (W-W) induced norm calculation method. This is then incorporated in the market-based control (MBC) theory and combined with the force analogy method (FAM) to solve the MBC robust strategy (R-MBC) of nonlinear systems. Finally, a single-degree-of-freedom (SDOF) system and a 9-stories steel frame structure are analyzed. The results are compared with those calculated by the $H{\infty}$-robust (R-$H{\infty}$) algorithm, and show the induced norm leads to the infinite control output as soon as it reaches the critical value. The R-MBC strategy has a better control effect than the R-$H{\infty}$ algorithm and has the advantage of strong strain capacity and short online computation time. Thus, it can be applied to large complex structures.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.3
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• pp.643-651
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• 1996

In this paper, to provide the possibility of various multimedia services, especially the collaborative work using the centralized control feature of the Service Node, is studied. We focused on the telewriting as the upper layer application to confirm the basic functions of the collaborative work. For this, we implement and add telewriting collaborative work function to the Service Node emulator, and terminals operating in the Windows environment are also developed. Through the tests on the system, we verify the basic functions related to the collaborative work are performed adequately, and confirm the concept of Service Node can support various type of multimedia conference services.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.272.1-272.1
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• 2002

We have carried out collaborative study to evaluate a preparation of antithrombin concentrate whether or not it was suitable to serve as the candidate for a Korea National Biological Standard. Six laboratories. including three manufacturers and three National Control Laboratories. participated in this study. The potency of this candidate preparation was determined using the heparin cofactor chromogenic method. (omitted)

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.5
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• pp.721-733
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• 2019

Objective: The objectives of this study were to investigate the thermal gelation properties and molecular forces of actomyosin extracted from two classes of chicken breast meat qualities (normal and pale, soft and exudative [PSE]-like) during heating process to further improve the understanding of the variations of functional properties between normal and PSE-like chicken breast meat. Methods: Actomyosin was extracted from normal and PSE-like chicken breast meat and the gel strength, water-holding capacity (WHC), protein loss, particle size and distribution, dynamic rheology and protein thermal stability were determined, then turbidity, active sulfhydryl group contents, hydrophobicity and molecular forces during thermal-induced gelling formation were comparatively studied. Results: Sodium dodecyl sulphate-polyacrylamide gel electrophoresis showed that protein profiles of actomyosin extracted from normal and PSE-like meat were not significantly different (p>0.05). Compared with normal actomyosin, PSE-like actomyosin had lower gel strength, WHC, particle size, less protein content involved in thermal gelation forming (p<0.05), and reduced onset temperature ($T_o$), thermal transition temperature ($T_d$), storage modulus (G') and loss modulus (G"). The turbidity, reactive sulfhydryl group of PSE-like actomyosin were higher when heated from $40^{\circ}C$ to $60^{\circ}C$. Further heating to $80^{\circ}C$ had lower transition from reactive sulfhydryl group into a disulfide bond and surface hydrophobicity. Molecular forces showed that hydrophobic interaction was the main force for heat-induced gel formation while both ionic and hydrogen bonds were different significantly between normal and PSE-like actomyosin (p<0.05). Conclusion: These changes in chemical groups and inter-molecular bonds affected protein-protein interaction and protein-water interaction and contributed to the inferior thermal gelation properties of PSE-like meat.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.4
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• pp.548-555
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• 2018

Objective: This experiment was conducted to investigate whether asparagine (Asn) could improve liver energy status in weaning pigs when challenged with lipopolysaccharide. Methods: Forty-eight weaned pigs ($Duroc{\times}Large\;White{\times}Landrace$, $8.12{\pm}0.56kg$) were assigned to four treatments: i) CTRL, piglets received a control diet and injected with sterile 0.9% NaCl solution; ii) lipopolysaccharide challenged control (LPSCC), piglets received the same control diet and injected with Escherichia coli LPS; iii) lipopolysaccharide (LPS)+0.5% Asn, piglets received a 0.5% Asn diet and injected with LPS; and iv) LPS+1.0% Asn, piglets received a 1.0% Asn diet and injected with LPS. All piglets were fed the experimental diets for 19 d. On d 20, the pigs were injected intraperitoneally with Escherichia coli LPS at $100{\mu}g/kg$ body weights or the same volume of 0.9% NaCl solution based on the assigned treatments. Then the pigs were slaughtered at 4 h and 24 h after LPS or saline injection, and the liver samples were collected. Results: At 24 h after LPS challenge, dietary supplementation with 0.5% Asn increased ATP concentration (quadratic, p<0.05), and had a tendency to increase adenylate energy charges and reduce AMP/ATP ratio (quadratic, p<0.1) in liver. In addition, Asn increased the liver mRNA expression of pyruvate kinase, pyruvate dehydrogenase, citrate synthase, and isocitrate dehydrogenase ${\beta}$ (linear, p<0.05; quadratic, p<0.05), and had a tendency to increase the mRNA expression of hexokinase 2 (linear, p<0.1). Moreover, Asn increased liver phosphorylated AMP-activated protein kinase (pAMPK)/total AMP-activated protein kinase (tAMPK) ratio (linear, p<0.05; quadratic, p<0.05). However, at 4 h after LPS challenge, Asn supplementation had no effect on these parameters. Conclusion: The present study indicated that Asn could improve the energy metabolism in injured liver at the late stage of LPS challenge.

• Journal of Digital Convergence
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• v.10 no.6
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• pp.189-196
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• 2012

In this paper, we propose a Scorm-based Sequencing & Navigation Model for Collaborative Learning. It is an e-Learning process control model that is used to efficiently and graphically defining Scorm's content aggregation model and its sequencing prerequistites through a formal approach. To define a process based model uses the expanded ICN(Information Control Net) model. which is called SCOSNCN(SCO Sequencing & Navigation Control Net). We strongly believe that the process-driven model delivers a way of much more convenient content aggregating work and system, in terms of not only defining the intended sequence and ordering of learning activities, but also building the runtime environment for sequencing and navigation of learning activities and experiences.

• Journal of Korean Home Economics Education Association
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• v.30 no.3
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• pp.195-213
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• 2018

The purpose of this study is to verify the effect by developing and applying a new program for improvement of creative problem solving ability and collaborative ability. Development of a sewing practice program was performed through the ADDIE model. The subjects of the study were 1^st grade middle school students and the research plan of the study was pretest-posttest control group design. The study method was performed by mixing the quantitative and qualitative analysis methods. Results of this study are as follows. First, the students in the experimental group showed higher creative problem solving ability than the students in the control group, but the difference was not significant at the 5% significance level. Qualitative analysis results indicated that creative problem solving ability is closely related to learning experiences involving the 'generation of diverse ideas', 'rebirth of creative ideas', 'self-directed learning plan', 'active problem solving', 'immediate feedback'. Second, the students in the experimental group showed a significantly higher level of collaborative ability than the students in the control group. This demonstrated that the program developed in this study had an effect on fostering the collaborative ability of middle school students. It was found that collaborative ability is closely related to learning experiences involving 'forming a positive atmosphere', 'continuous interaction', and 'working together'.

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.170.5-170
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• 2001

As close competitions are being fought out among enterprises, they should accomplish their objectives such as reduction of cost, improvement of quality and condensation of due date, etc. For this objects, it becomes very important to manage the workflow harmoniously and to share the information efficiently between geographically dispersed users. We developed the collaborative design system, which manages various design process and enables to share design information. In this paper, Internal-based collaboration system for press die design process in the automobile manufacturer is developed with CORBA, Java and relational database system. After modeling real press die design process with UML language, workflow routing path is created by modeling data. Cost and time for ...