• The Bulletin of The Korean Astronomical Society
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• v.32 no.2
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• pp.21-21
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• 2007

• 한국당과학회:학술대회논문집
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• 2006.11a
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• pp.56-56
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• 2006

• The Journal of Korean Medicine
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• v.25 no.4
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• pp.8-14
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• 2004

Objective : Achyranthes japonica Nakai (AJ) has been classified as a herb that activates blood flow and clears the stagnated blood. In this study, we evaluated its anti-nociceptive and anti-inflammatory activity in animals to clarify the effect of AJ on pain or inflammation. Methods : ICR mice and Sprague-Dawley rats were pretreated with an ethanolic extract of AJ with two dosages of 200 mg/kg (p.o.) and 400 mg/kg (p.o.). Nociceptive responses of acute pain were determined by hotplate and tail-flick tests. The effects of AJ on inflammation were evaluated by flexion/extention test and mechanical hyperalgesia test in models induced by both carrageenan and Complete Freund's Adjuvant (CFA). Results : AJ showed significant analgesic effects in both hotplate and tail-flick tests at the dose of 400 mg/kg. It also produced a significant inhibition of carrageenan-induced paw edema and CFA induced arthritis in rats at the dose of 400 mg/kg. Conclusion : We have demonstrated the analgesic and anti-inflammatory properties of an 80% ethanolic extract of AJ in animals. This suggests the application of AJ in relief of pain or inflammatory disease.

• Journal of Technology Innovation
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• v.16 no.2
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• pp.17-40
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• 2008

The collaboration among academia, industry, and public research sector gains importance in these days. This is essential for implement competent regional and national innovation systems. There have been many governmental programs for activating collaboration among innovation actors. Most policy programs for collaboration have aimed at increasing S&T and innovation potential and constructing S&T infrastructure. However, Korea has not produced a sufficient level of collaboration, especially on regional level. Most policy programs could not reach regions and many regions have no enough innovation actors. In order to activate R&D collaboration, therefore, we suggest that Korean S&T community should build and implement "collaborative research centers" all over the regions. This concept is very new approach, especially because it focuses on collaboration among regional innovation actors. In this paper, we discuss a concept, type, and execution strategy of collaboration research centers. We expect that these centers will play an important role in implementing successful regional innovation systems, as they will link regional innovation actors very closely.

• Journal of Information Science Theory and Practice
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• v.10 no.spc
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• pp.12-24
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• 2022

This study attempted to investigate changes in collaboration structure for each stage of national Research and Development (R&D) in the artificial intelligence (AI) field through analysis of a co-author network for papers written under national R&D projects. For this, author information was extracted from national R&D outcomes in AI from 2014 to 2019. For such R&D outcomes, NTIS (National Science & Technology Information Service) information from the KISTI (Korea Institute of Science and Technology Information) was utilized. In research collaboration in AI, power function structure, in which research efforts are led by some influential researchers, is found. In other words, less than 30 percent is linked to the largest cluster, and a segmented network pattern in which small groups are primarily developed is observed. This means a large research group with high connectivity and a small group are connected with each other, and a sporadic link is found. However, the largest cluster grew larger and denser over time, which means that as research became more intensified, new researchers joined a mainstream network, expanding a scope of collaboration. Such research intensification has expanded the scale of a collaborative researcher group and increased the number of large studies. Instead of maintaining conventional collaborative relationships, in addition, the number of new researchers has risen, forming new relationships over time.

• Korean Journal of Health Education and Promotion
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• v.26 no.4
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• pp.83-90
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• 2009

Objectives: As collaboration for community health promotion is much emphasized, the concept and process of community collaboration for health needs to be discussed. This paper discusses varying types of collaboration and collaboration building processes and suggests directions for enhancing community collaboration research and practice. Methods: Leading literature on community partnership building and community health development and current community partnership research program information were reviewed. Results: Although the term collaboration is used interchangeably with cooperation, partnership, network, or coalition, conceptual differences need to be acknowledged in order to develop and reinforce the processes of collaboration. Collaboration building goes in hand with community-based participatory research and systems thinking, which should be supported by long-term, systematic planning and evaluation research. Conclusion: Collaboration for community health promotion needs to be defined and agreed conceptually, thus collaboration process can be developed. Effective collaboration building will be facilitated by systematic thinking and participatory research. Research support system should appreciate the time-intensive, process-oriented nature of collaboration building by providing long-term research funding and emphasizing process and long-term evaluation.

• Journal of Microbiology and Biotechnology
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• v.29 no.1
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• pp.21-29
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• 2019

The effects of Lavandula angustifolia extract fermented with Pediococcus pentosaceus DK1 on UVB-mediated MMP-1 expression and collagen decrease in human skin fibroblasts were determined, and the conversion of its components was also analyzed. Fermentation was performed at varying L. angustifolia extract and MRS medium concentrations, and optimal fermentation conditions were selected. L. angustifolia extracts showed decreased cytotoxicity after fermentation in the fibroblasts. UVB-irradiated fibroblasts treated with fermented L. angustifolia extract showed MMP-1 expression 8.2-14.0% lower than that in UVB-irradiated fibroblasts treated with non-fermented extract. This was observed even at fermented extract concentrations lower than those of non-fermented extracts. Fibroblasts treated with fermented L. angustifolia extract showed 20% less reduction in collagen production upon UVB irradiation than those treated with non-fermented extracts. UVB-irradiated fibroblasts treated with fermented L. angustifolia extracts showed 50% higher inhibition of ROS generation than those treated with non-fermented extract. Luteolin and apigenin glycosides of L. angustifolia were converted during fermentation, and identified using RP-HPLC and LC/ESI-MS. Therefore, the effects of L. angustifolia extract on MMP-1 expression and collagen decrease in UVB-irradiated human skin fibroblasts were increased through fermentation by P. pentosaceus.

• Asian Journal for Public Opinion Research
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• v.4 no.4
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• pp.205-207
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• 2017

• IE interfaces
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• v.23 no.2
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• pp.182-192
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• 2010

Customer needs for final products are very unpredictable because product specifications and technologies are being improved very quickly thereby their requirement level is also elevated correspondingly. In order to survive and to enhance competitiveness in the global market, many manufacturing companies are trying to find a breakthrough from collaborization. Even though they want to collaborate with others, however, they do not exactly know what kind of system they have to develop or which technology they have to use. In this paper, therefore, we first investigate status and trend of information systems and infrastructure that are essential for collaboration. We then clearly describe definition and classification of collaboration with various point of views considering collaboration pattern, timing condition of collaborative activities, organizational structure, etc. With web-based collaboration systems already developed by i-Manufacturing (Korean-style Manufacturing Innovation) project, led by Korean government from 2004, we introduce main functions and analyze collaboration types of each system. Strategically important technologies for supporting collaboration will also be illustrated by reorganizing collaborization technologies after evaluating them with respect to emergency and importance of each technology. We hope this research will provide a guideline on collaboration especially for small and medium sized manufacturing companies.

• Korean Journal of Health Education and Promotion
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• v.30 no.4
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• pp.77-85
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• 2013

Objectives: This paper discusses the current contexts of the collaboration between public health centers(PHCs) and community partners for health promotion. Then it suggests directions for the development and enhancement of the collaboration. Methods: The discussion in this paper is based on key literature on community health promotion, including literature reviews and case reports. Results: PHCs are mostly engaged in networking and cooperation rather than collaboration with the community. A typical pattern of cooperation is where PHCs provide healthy-setting types of programs to the community in single-partnered relationships. Current cooperation rarely involves co-planning by a multi-partnered partnership, and is greatly influenced by the interest of PHC directors and PHC performance evaluation indicators. Systems change is recommended to foster collaboration for community health promotion. Such change involves: shared understanding of health promotion and collaboration, inclusion of collaboration mechanism in public health governance, leadership development, capacity enhancement of all partners. role definition of PHCs for community collaboration, and development of collaborative system, at the least. Conclusions: At this point where collaboration should be more than rhetoric, multi-faceted, intersectoral, and concurrent approaches are required to create discourses, to develop cases, and to share experience for actual realization of collaboration for community health promotion.