• The Journal of the Korean life insurance medical association
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• v.2 no.1
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• pp.128-134
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• 1985

Circumscribed solitary pulmonary nodule is often founded on the plain chest P-A. Even if many study results of coin lesion have been reported by some scholars, it is still very difficult to judge whether the coin lesion is to be benign or malignant. In order to avoid unnecessary surgical treatment, it must be made an examination and analysis very carefully in advance. In the chest P-A, we can grasp the aspects of the site and size of lesion, marginal state of lesion, calcification, cavity, and the growth rate in comparison to follow-up chest P-A. On the basis of above-mentioned analysis, we have to judge whether it is benign or malignant, and decide the next examinations. And then the doctor make diagnosis definitely by the clinical history, plain chest P-A, tomography, bronchography, CT, variable laboratory findings.

• Journal of Korean Neurosurgical Society
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• v.48 no.1
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• pp.85-87
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• 2010

We experienced a rare case of solitary syphilitic osteomyelitis of the skull without any other clinical signs or symptoms of syphilis. A 20-year-old man was referred due to intermittent headache and mild tenderness at the right parietal area of the skull with a palpable coin-sized lesion of softened cortical bone. On radiological studies, the lesion was a radiolucent well enhanced mass (17 mm in diameter). The erythrocyte sedimentation rate (52 mm/h) and C-reactive protein (2.24 mg/dL) were elevated on admission. Serum venereal disease research laboratory (VDRL) and Treponema pallidum haemagglutination assay (TPHA) tests were positive. There were no clinical signs or symptoms of syphilis. After treatment with benzathine penicillin, we removed the lesion and performed cranioplasty. The pathologic finding of the skull lesion was fibrous proliferation with lymphoplasmocytic infiltration forming an osteolytic lesion. In addition, a spirochete was identified using the Warthin-starry stain. The polymerase chain reaction study showed a positive band for Treponema pallidum. Solitary osteomyelitis of the skull can be the initial presenting pathological lesion of syphilis.

• Journal of Chest Surgery
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• v.13 no.3
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• pp.298-300
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• 1980

The hamartoma is the most common benign tumor of the lung, but the incidence is very low. Most of hamartomas are revealed accidentally as coin lesion of routine chest X-ray because of no symptoms usually. The differential diagnosis should include tuberculoma, bronchogenic carcinoma, and other forms of tumor. Definitive diagnosis usually is established at exploratory thoracotomy. In this report, we present one case of a 42-year-old female having hamartoma of the left lower lobe of the lung that removed successfully and confirmed histopathologically. Her postoperative course was uneventful. She was discharged in good condition.

• Journal of Chest Surgery
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• v.22 no.4
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• pp.709-712
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• 1989

The hamartoma is the commonest benign tumor of the lung and proved incidentally as asymptomatic coin lesion on routine chest radiologic examination, but has very low incidence, especially in endobronchial origin. The authors experienced a case of coincidental with intrapulmonary and endobronchial hamartoma. The patient, a 60-year-old man, a farmer, was admitted due to coughing and fever. Preoperative diagnosis was achieved by flexible bronchoscopic biopsy and managed by right middle lobectomy. Three lobulated masses were palpable in the right middle lobe. He was discharged on 15th postoperative day, without problem.

• The Korean Journal of Cytopathology
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• v.11 no.1
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• pp.19-24
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• 2000

Pulmonary hamartomas are uncommon benign tumors, usually discovered radiologically as a solitary coin lesion in asymptomatic individual. The approach to the patient with a peripheral lung nodule has changed with the increasing acceptance of fine needle aspiration cytology(FNAC) as a rapid, safe, inexpensive, and highly accurate diagnostic tool. However, a few reports describing the FNAC findings of pulmonary hamarioma have appeared in the cytologic literature and the experience of FNAC is limited. We reviewed all 9 cases of pulmonary hamartoma with histologic confirmation after FNAC seen at Asan Medical Center since 1995 to evaluate cytologic findings and to determine the value of FNAC in identifying that lesion. Originally, seven of nine patients were diagnosed as pulmonary hamartoma, while two patients were diagnosed as inflammatory lesion and adenocarcinoma of each. On review, eight of nine patients were considered as diagnostic of pulmonary hamartoma. The diagnostic findings in FNAC of pulmonary hamartoma were the presence of fibrillary myxoid tissue with spindle cells as well as hyaline cartilage.

• Journal of Chest Surgery
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• v.9 no.2
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• pp.169-174
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• 1976

Since. its first description by Albrecht in 1904 that hamartoma (Greek. meaning "error" and "tumor")is tumor-like malformation characterized by abnormal mixture of normal constituent in any organ it arises, hamartoma involving the lung has assumed the following clinical features.: 1) all the pulmonary lesions presenting as "coin lesions", it occupies about 8% according to various reports. It also constitutes the most prevalent lesion of all the benign lung tumors, appearing in 0.25% of the general population. 2) Peak incidence of the lesion occurs in the 5th and 6th decade as the carcinoma patient do, and the occasional growing tendency and periperal location as in this presentation renders the differential diagnosis from the malignant disease difficult and surgical intervention inevitable for definite histological diagnosis and treatment. 3) Nearly all the clinical investigations such as history, physical exam, bronchoscopy, culture, and cytological exam of sputum sre likely to futile:the only tool for detecting the presence of the lesion is X-ray, butthat's short of telling the true nature of it. 4) Because of its age of presentation and growing tendency in middle-aged adult, it still controversial whether it is developmental anomaly as Albrecht described, or true neoplasm denovo of fibrous connective tissue origin. This is a case report of surgical experience of pulmonary hamartoma which had nearly all the typical clinical features above mentioned and was reviewed with related literatures.

• The Korean Journal of Cytopathology
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• v.2 no.1
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• pp.28-35
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• 1991

So-called sclerosing hemangioma of the lung is a rare benign neoplasm which usually presents with a coin lesion detected through routine chest X-ray. We report two cases showing characteristic cytologic appearances which have been rarely reported. Both cases were young females with coin lesions in the lung. Fine needle aspiration of each case revealed unique but some different cytologic features. Case 1 showed bland-looking polygonal epithelial cells resembling bronchioloalveolar cells haying predominantly papillary configurations with loosely arranged solid sheets or isolated cells. Cytoplasms were plump, cyanophilic, and finely granular, with eccentric nuclei. The nuclei were usually monotonous, round-to-ovoid, and vesicular with a small but conspicuous nucleolus. In comparison to case 1, case 2 revealed largely loose pavement-like solid sheets or clusters rather than papillary patterns in the hemorrhagic background. The size of tumor cells were a little smaller than that of case 1. Bronchioloalveolar carcinoma and papillary adenocarcinoma of metastatic origin were considered to be one of the important differential diagnoses with these cytologic features. Histologically, both cases exhibited findings compatible with so-called sclerosing hemangioma of the lung.

• Journal of Chest Surgery
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• v.15 no.2
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• pp.155-161
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• 1982

The term hamartoma was first used by Albrecht to describe what he considered to be localized errors of development involving one or more tissue native to the organ of origin. The definition was meant to encompass not only abnormal local growth rate, but also the spatial arrangement, relative proportions and degree of the component tissue. But lately the major conclusions are that this group of lesion is neoplastic than developmental in origin. The Importance of pulmonary hamartoma is that they are relatively common among the benign tumor of the lung, but they usually present as asymptomatic coin lesion on chest x-ray film and were find out In routine check up and frequently mimic clinically the more common lung tumor such as cancer. Recently, we have experienced three cases of pulmonary hamartoma which were all discovered during routine chest film check up for certificate of health and evaluation of other disease. All of these were surgically resected with good result. Among the operations, one of these was mass enucleation and the others were lobectomy of lung involved by the mass.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.14 no.1
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• pp.111-116
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• 2001

Nummular eczema is well-shaped, coin-like lesion. Usually it is surrounded by the papules and vesicles, and is likely to be the impetigo. It's said that nummular eczema is combined with atopic dermititis, contact dermatitis, bacterial infection and so on. Recently, we experienced a nummular eczema with impetigo and that was successfully treated by the herb-medication and the ceramic resonance therapy. The medications taken by the patient were yunwhasagnatang and gamisopungsan which is used to treat allergic disease and make immune system be strong. The former effects the liver to be cool down and healthy and it also has anti-imflamatory reactions like the corticosteroid hormone. Ceramic resonance therapy utilises irradiation within the frequency range of the radiation emitted by the human body. So we report this case with a brief review of the oriental medical and medical literatures.

• Journal of Chest Surgery
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• v.11 no.1
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• pp.97-101
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• 1978

Primary cyst of the diaphragm is a rather uncommon disease. This is a report of a case of diaphragmatic cyst, located in the tendinous portion of the right diaphragm. The patient had no specific symptoms in the respiratory systems, but suffered from gastrointestinal symptoms [indigestion, epigastralgia, and loss of appetite etc.] for 2 months. Accidentally, on a simple chest x-ray examination, a round homogenous mass density was discovered. Tomography showed a well circumscribed parenchymatous mass. So a coin lesion in the medial segment of the right lower lobe was suspected. A thoracotomy was performed. There were no pathological findings in the lung and pleura. A ping-pong ball sized round mass, which was soft, elastic and fluctuated,was noted in the tendinous portion of the diaphragm. It was enucleated completely without diaphragmatic rupture, and diagnosed as a primary diaphragmatic cyst [fibrous-walled] by the histopathologic examination. Postoperative course was uneventful.