• Title/Summary/Keyword: coefficient-based method

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Quantitative Analysis of Kynurenic Acid in Chestnut Honey from Different Regions and Method Validation (산지별 밤꿀에 함유된 Kynurenic Acid의 정량 분석과 분석법 검증)

  • Kim, Juree;Kim, Doyun;Lee, Sanghyun
    • Korean Journal of Pharmacognosy
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    • v.53 no.2
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    • pp.111-118
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    • 2022
  • Chestnut honey is a sweet dark-colored honey with a distinct bitter aftertaste. It contains numerous phenolic compounds and alkaloids and is noted for its antioxidant and anti-inflammatory activities. However, it has been established that there are differences in the composition and activity of chestnut honey constituents depending on the region of origin, the sources of which warrant further research. In this study, we analyzed the kynurenic acid (KA) contents in chestnut honey produced in nine different regions in Korea, using high-performance liquid chromatography in conjunction with ultraviolet detection, and validated the analytical method developed. Use of a reverse-phase column and detection at a wavelength of 240 nm were found to be optimal for the detection of KA. Similar evaluation of an optimal method for extracting KA from chestnut honey revealed that extraction using 10% EtOH at 20 times the sample volume over a 6 h period was the most suitable for obtaining a high content of KA. Among the nine regional chestnut honeys assessed, KA content was found to be highest in the "Gongju" sample (1.14 mg/g), followed by that in the "Cheongdo" and "Damyang" samples. Validation of the KA analytical method revealed a good analyte linearity, with a correlation coefficient (r2) of 0.9995, an accuracy of between 92.37% and 107.35%, and good precision (RSD ≤ 1.05%). Our findings in this study, based on a validated quantitative analytical method for KA, could make an important contribution to establishing a data profiling procedure for characterizing chestnut honeys produced in different regions, and may also provide basic data for the identification of functional honey.

Estimation of Axial toad Capacity for Tapered Piles Using Equivalent Transformation (등가변형을 이용한 테이터 말뚝의 지지력 산정)

  • Jun, Sung-Nam;Seo, Kyung-Bum;Song, Won-Jun;Lee, Jun-Hwan
    • Journal of the Korean Geotechnical Society
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    • v.25 no.8
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    • pp.57-64
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    • 2009
  • In this study, a method using equivalent transformation for estimation of the axial load capacity of tapered piles is proposed. While preexistent methods for estimating the axial load capacity of tapered piles have been based on the effect of soil state and taper angle, a new design method is proposed considering cone resistance $q_c$ and equivalent transformation in sand. Through tapered pile simplified by using equivalent transformation, a new method fur quick and easy estimation of the axial load capacity of tapered pile is proposed for practical use. In order to verify the proposed method, calibration chamber test and field test were conducted. In calibration chamber test, comparison of estimated axial load capacity with measured one showed that the standard deviation and COV (Coefficient Of Variation) of estimated $Q_t$ is $0.05{\sim}0.121$, $0.04{\sim}0.05$ respectively. For field test, axial load capacity by proposed method shows 2.5% under-estimation in comparison with measured value. As a result, it is found that proposed method produces satisfactory predictions for tapered piles.

The Effect of Slope-based Curve Number Adjustment on Direct Runoff Estimation by L-THIA (경사도에 따른 CN보정에 의한 L-THIA 직접유출 모의 영향 평가)

  • Kim, Jonggun;Lim, Kyoung Jae;Park, Younshik;Heo, Sunggu;Park, Joonho;Ahn, Jaehun;Kim, Ki-sung;Choi, Joongdae
    • Journal of Korean Society on Water Environment
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    • v.23 no.6
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    • pp.897-905
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    • 2007
  • Approximately 70% of Korea is composed of forest areas. Especially 48% of agricultural field is practiced at highland areas over 400 m in elevation in Kangwon province. Over 90% of highland agricultural farming is located at Kangwon province. Runoff characteristics at the mountainous area such as Kangwon province are largely affected by steep slopes, thus runoff estimation considering field slopes needs to be utilized for accurate estimation of direct runoff. Although many methods for runoff estimation are available, the Soil Conservation Service (SCS), now Natural Resource Conservation Service (NRCS), Curve Number (CN)-based method is used in this study. The CN values were obtained from many plot-years dataset obtained from mid-west areas of the United States, where most of the areas have less than 5% in slopes. Thus, the CN method is not suitable for accurate runoff estimation where significant areas are over 5% in slopes. Therefore, the CN values were adjusted based on the average slopes (25.8% at Doam-dam watershed) depending on the 5-day Antecedent Moisture Condition (AMC). In this study, the CN-based Long-Term Hydrologic Impact Assessment (L-THIA) direct runoff estimation model used and the Web-based Hydrograph Analysis Tool (WHAT) was used for direct runoff separation from the stream flow data. The $R^2$ value was 0.65 and the Nash-Sutcliffe coefficient value was 0.60 when no slope adjustment was made in CN method. However, the $R^2$ value was 0.69 and the Nash-Sutcliffe value was 0.69 with slope adjustment. As shown in this study, it is strongly recommended the slope adjustment in the CN direct runoff estimation should be made for accurate direct runoff prediction using the CN-based L-THIA model when applied to steep mountainous areas.

Study on Failure Characteristics of Laminate with a Hole (원공이 있는 복합적층판의 파괴특성 연구)

  • K.H.,Song;J.W.,Lee
    • Bulletin of the Society of Naval Architects of Korea
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    • v.26 no.4
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    • pp.67-80
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    • 1989
  • This Paper is concerned with the fracture behavoir of Unidirectional Laminate(UD) and the characteristic length of Multidirectional Laminate(MD) around hole under the Uniform Tensial Strain. Two fracture mechanical concepts of the Waddoups-Eisenman-Kaminski(WEK) model based on the Linear Elastic Fracture Mechanics(LEFM) and the Whitney-Nuismer Model based on Point and Average Stress Criteria were applied. The characteristic length of a laminate with a hole is then obtained using the coefficient of stress reduction and the experimental results, and it can be utilized in predicting the stress level at which the specimen will fracture. The results of the fracture characteristics and the strength of the specimens having a hole in the center can be used as the important experimental data in the research branch of the mechanical fastening of laminated structures. The Ultrasonic scanning and the Acoustic Emission(AE) method were utilized in order to find out the initial defects and the fracture behavior, respectively.

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Studies on the Integrated Stream Naturalness Assessment Based on Abiotic and Biotic Factors (비생물 및 생물 요인에 기초한 통합적 하천자연도 평가기법에 관한 연구)

  • Pyo, Jae-Hun;Mun, Hyeong-Tae
    • Journal of Environmental Impact Assessment
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    • v.20 no.1
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    • pp.61-69
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    • 2011
  • Integrated stream naturalness based on abiotic and biotic factors were developed. Abiotic factors considered in this study were types of land use in the riparian area, river bank and high water bed streamside, revetment, bed substrate and artificial construction of streamside. Biotic factors included types of vegetation, assemblages of fish, macroinvertebrate, bird and mammal(Otter) in streams. The presence/absence of legal species and biological assessment index were also weighted as important parameters in this study. Scoring criteria selected for each matrix was five rating system; 1=poor, 2=moderate, 3=fair, 4=good, 5=excellent. Numerical ratings for the matrix were then summed. This resulted in a minimum score of 13 if all matrix at a site were poor, and a maximum score of 65 if all matrix were excellent. Five grade system from poor(I) to excellent condition(V) was employed. To verify its validity in natural environment, the evaluation system was applied to the Gapchun stream which is a test bed selected. Our result showed that stream naturalness of each reach was clearly distinguished by biotic and abiotic characteristics. Determination of correlation coefficient between abiotic and biotic factors was also high ($R^2=0.96$, p<0.05). In conclusion, assessment for stream naturalness reflecting abiotic and biotic factors was useful method representing stream integrated.

The Comparative Study based on Gompertz Software Reliability Model of Shape Parameter (곰페르츠형 형상모수에 근거한 소프트웨어 신뢰성모형에 대한 비교연구)

  • Shin, Hyun Cheul;Kim, Hee Cheul
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.10 no.2
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    • pp.29-36
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    • 2014
  • Finite failure NHPP software reliability models presented in the literature exhibit either constant, monotonic increasing or monotonic decreasing failure occurrence rates per fault. In this paper, proposes the Gompertz distribution reliability model, which made out efficiency application for software reliability. Algorithm to estimate the parameters used to maximum likelihood estimator and bisection method, model selection based on mean square error (MSE) and coefficient of determination$(R^2)$, for the sake of efficient model, was employed. Analysis of failure using real data set for the sake of proposing fixed shape parameter of the Gompertz distribution was employed. This analysis of failure data compared with the Gompertz distribution model of shape parameter. In order to insurance for the reliability of data, Laplace trend test was employed. In this study, the proposed Gompertz model is more efficient in terms of reliability in this area. Thus, Gompertz model can also be used as an alternative model. From this paper, software developers have to consider the growth model by prior knowledge of the software to identify failure modes which can was helped.

A Study of Physical Condition Predicting Model Development of Plastic Pipes in Water Mains (플라스틱 관종의 물리적 상태예측모형 개발)

  • Ki, Nam-Yeoun;Bae, Cheol-Ho;Lee, Doo-Jin;Jung, Kwan-Sue
    • Journal of Korean Society of Water and Wastewater
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    • v.26 no.6
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    • pp.871-881
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    • 2012
  • This study suggested a model that can predict a degradation condition over time of two plastic pipes, PE and PVC, which are currently used in the country. This study was analyzed physical characteristics change of plastic pipes by comparison with initial physical characteristics (on the case of new pipes). Since this is dependent on accidents that already occurred, there are limitations that it only decides a priority on improvement based on relative corrosion status rather than precautionary aspects. The comparison results between physical degradation by the deducted performance rating and a conventional numerical scoring method showed that correlation coefficient was 0.67 for PE pipes and 0.86 for PVC pipes, indicating a high correlation. According to this result, it has been decided that the performance rating suggested herein can be applied naturally to the criterion of an improvement decision, which was based on Scoring System. From results of the research, it is expected that a reliable result can be provided to an improvement decision process related to degradation of plastic pipes by comprehensively comparing and evaluating a condition of pipe materials(direct factors) and an environmental impact(indirect factors).

Internal Fault Detection and Fault Type Discrimination for AC Generator Using Detail Coefficient Ratio of Daubechies Wavelet Transform (다우비시 웨이브릿 변환의 상세계수 비율을 이용한 교류발전기의 내부고장 검출 및 고장종류 판별)

  • Park, Chul-Won;Shin, Kwang-Chul;Shin, Myong-Chul
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.58 no.2
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    • pp.136-141
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    • 2009
  • An AC generator is an important components in producing a electric power and so it requires highly reliable protection relays to minimize the possibility of demage occurring under fault conditions. Conventionally, a DFT based RDR has been used for protecting the generator stator winding. However, when DFTs based on Fourier analysis are used, it has been pointed out that defects can occur during the process of transforming a time domain signal into a frequency domain one which can lead to loss of time domain information. This paper proposes the internal fault detection and fault type discrimination for the stator winding by applying the detailed coefficients by Daubechies Wavelet Transform to overcome the defects in the DFT process. For the case studies reported in the paper, a model system was established for the simulations utilizing the ATP, and this verified the effectiveness of the proposed technique through various off-line tests carried out on the collected data. The propose method is shown to be able to rapidly identify internal fault and did not operate a miss-operation for all the external fault tested.

Three-Dimensional Visualization of Medical Image using Image Segmentation Algorithm based on Deep Learning (딥 러닝 기반의 영상분할 알고리즘을 이용한 의료영상 3차원 시각화에 관한 연구)

  • Lim, SangHeon;Kim, YoungJae;Kim, Kwang Gi
    • Journal of Korea Multimedia Society
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    • v.23 no.3
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    • pp.468-475
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    • 2020
  • In this paper, we proposed a three-dimensional visualization system for medical images in augmented reality based on deep learning. In the proposed system, the artificial neural network model performed fully automatic segmentation of the region of lung and pulmonary nodule from chest CT images. After applying the three-dimensional volume rendering method to the segmented images, it was visualized in augmented reality devices. As a result of the experiment, when nodules were present in the region of lung, it could be easily distinguished with the naked eye. Also, the location and shape of the lesions were intuitively confirmed. The evaluation was accomplished by comparing automated segmentation results of the test dataset to the manual segmented image. Through the evaluation of the segmentation model, we obtained the region of lung DSC (Dice Similarity Coefficient) of 98.77%, precision of 98.45%, recall of 99.10%. And the region of pulmonary nodule DSC of 91.88%, precision of 93.05%, recall of 90.94%. If this proposed system will be applied in medical fields such as medical practice and medical education, it is expected that it can contribute to custom organ modeling, lesion analysis, and surgical education and training of patients.

Application of RAPD markers for characterization of ${\gamma}$-ray-induced rose mutants and assessment of genetic diversity

  • Chakrabarty, D.;Datta, S.K.
    • Plant Biotechnology Reports
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    • v.4 no.3
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    • pp.237-242
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    • 2010
  • Six parent and their 12 gamma ray-induced somatic flower colour mutants of garden rose were characterized to discriminate the mutants from their respective parents and understanding the genetic diversity using Random amplification of polymorphic DNA (RAPD) markers. Out of 20 primers screened, 14 primers yielded completely identical fragments patterns. The other 7 primers gave highly polymorphic banding patterns among the radiomutants. All the cultivars were identified by using only 7 primers. Moreover, individual mutants were also distinguished by unique RAPD marker bands. Based on the presence or absence of the 48 polymorphic bands, the genetic variations within and among the 18 cultivars were measured. Genetic distance between all 18 cultivars varied from 0.40 to 0.91, as revealed by Jaccard's coefficient matrix. A dendrogram was constructed based on the similarity matrix using the Neighbor Joining Tree method showed three main clusters. The present RAPD analysis can be used not only for estimating genetic diversity present in gamma ray-induced mutants but also for correct identification of mutant/new varieties for their legal protection under plant variety rights.