• Title/Summary/Keyword: co-multiplication

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High-throughput and low-area implementation of orthogonal matching pursuit algorithm for compressive sensing reconstruction

  • Nguyen, Vu Quan;Son, Woo Hyun;Parfieniuk, Marek;Trung, Luong Tran Nhat;Park, Sang Yoon
    • ETRI Journal
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    • v.42 no.3
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    • pp.376-387
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    • 2020
  • Massive computation of the reconstruction algorithm for compressive sensing (CS) has been a major concern for its real-time application. In this paper, we propose a novel high-speed architecture for the orthogonal matching pursuit (OMP) algorithm, which is the most frequently used to reconstruct compressively sensed signals. The proposed design offers a very high throughput and includes an innovative pipeline architecture and scheduling algorithm. Least-squares problem solving, which requires a huge amount of computations in the OMP, is implemented by using systolic arrays with four new processing elements. In addition, a distributed-arithmetic-based circuit for matrix multiplication is proposed to counterbalance the area overhead caused by the multi-stage pipelining. The results of logic synthesis show that the proposed design reconstructs signals nearly 19 times faster while occupying an only 1.06 times larger area than the existing designs for N = 256, M = 64, and m = 16, where N is the number of the original samples, M is the length of the measurement vector, and m is the sparsity level of the signal.

Can Cancer Therapy be Achieved by Bridging Apoptosis and Autophagy: a Method Based on microRNA-Dependent Gene Therapy and Phytochemical Targets

  • Vijayarathna, Soundararajan;Gothai, Sivapragasam;Jothy, Subramanion L;Chen, Yeng;Kanwar, Jagat R;Sasidharan, Sreenivasan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7435-7439
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    • 2015
  • A failure of a cell to self destruct has long been associated with cancer progression and development. The fact that tumour cells may not instigate cell arrest or activate cell death mechanisms upon cancer drug delivery is a major concern. Autophagy is a mechanism whereby cell material can be engulfed and digested while apoptosis is a self-killing mechanism, both capable of hindering multiplication after cell injury. In particular situations, autophagy and apoptosis seem to co-exist simultaneously or interdependently with the aid of mutual proteins. This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage.

Properties on Tourmaline Treated-water and it's Disinfection, Suppression Effects of Bacteria Multiplication (투어멀린 처리수의 특성과 세균번식억제 및 살균 작용)

  • Soh, Dea-Wha;Park, Jung-Cheul;Lee, Woo-Sik;Jang, Dong-Hoon
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.07a
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    • pp.237-242
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    • 2003
  • 투어멀린(Tourmaline)은 비대칭 쌍극자를 가진 유극성 결정체로 광물 중에서 영구적으로 전기분극 특성을 띄고 있는 유일한 물질로써, 일명 "전기석"이라고 알려져 있다. 자체의 미약 전류(약 0,06mA)와 함께 음이온 및 원적외선의 발생으로 최근 우리 주변에서 건강과 환경정화를 위한 관심 대상의 투어멀린은 육방정계의 압전성 및 초전성을 띄는 붕규산염으로, 물분자를 만나면 수소($H^+$)와 수산기($OH^-$)로 분해하여 친수기와 소수기를 구분하여 발생하며, $H^+$$OH^-$는 각각 $H_2O$와 결합하여 활성이 강한 hydronium ion($H_3O^+$)과 계면활성 작용이 있는 hydroxyl ion($H_3O_2^-$)을 생성한다. 물속에서 불안정한 상태로 존재하는 수산기는 hydroxyl (-)ion을 형성하여 약 알카리성($pH{\sim}7.4$)을 띄고, 물의 클러스터(cluster)를 세분화하는 수질개선 기능과 함께 살균, 항균 및 세균번식억제 효과를 갖는 것으로 확인되었다. 따라서 투어멀린 소결체를 활용하여 그 처리수의 특성조사 및 기능개발과 함께 대장균의 번식억제 작용 및 살균작용과 수질개선 기능 등 유용한 결과의 분석으로부터 다양한 응용성을 확보하였다.

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An Efficient Matrix-Vector Product Algorithm for the Analysis of General Interconnect Structures (일반적인 연결선 구조의 해석을 위한 효율적인 행렬-벡터 곱 알고리즘)

  • Jung, Seung-Ho;Baek, Jong-Humn;Kim, Joon-Hee;Kim, Seok-Yoon
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.38 no.12
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    • pp.56-65
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    • 2001
  • This paper proposes an algorithm for the capacitance extraction of general 3-dimensional conductors in an ideal uniform dielectric that uses a high-order quadrature approximation method combined with the typical first-order collocation method to enhance the accuracy and adopts an efficient matrix-vector product algorithm for the model-order reduction to achieve efficiency. The proposed method enhances the accuracy using the quadrature method for interconnects containing corners and vias that concentrate the charge density. It also achieves the efficiency by reducing the model order using the fact that large parts of system matrices are of numerically low rank. This technique combines an SVD-based algorithm for the compression of rank-deficient matrices and Gram-Schmidt algorithm of a Krylov-subspace iterative technique for the rapid multiplication of matrices. It is shown through the performance evaluation procedure that the combination of these two techniques leads to a more efficient algorithm than Gaussian elimination or other standard iterative schemes within a given error tolerance.

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Effect of Quality Properties of Pomegranate Concentrate by Sterilization Conditions during Storage (살균조건이 석류농축액의 저장 중 품질특성에 미치는 영향)

  • Jang Se-Young;Yoon Kyung-Young;Jeong Yong-Jin
    • Food Science and Preservation
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    • v.13 no.4
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    • pp.445-449
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    • 2006
  • This study was carried out to investigate the quality properties of pomegranate concentrate with different sterilization conditions and storage temperature during storage. Total microbe level detected in non-sterilization pomegranate concentrate and the multiplication rate of total microbe level were higher at a storage temperature of $37^{\circ}C$ than at $10^{\circ}C$. Coliform was not detected in any of the samples. The pH was gradually increased but $^{\circ}Brix$ and total acidity were gradually decreased. Changes in a color values were gradually decreased but that of the sterilized pomegranate concentrate at $65^{\circ}C$(30 min) wasn't changed after storage at $10^{\circ}C$. The sterilization of pomegranate concentrate at $65^{\circ}C$ (30 min) could be useful for preservation.

COVID-19: an update on diagnostic and therapeutic approaches

  • Iyer, Mahalaxmi;Jayaramayya, Kaavya;Subramaniam, Mohana Devi;Lee, Soo Bin;Dayem, Ahmed Abdal;Cho, Ssang-Goo;Vellingiri, Balachandar
    • BMB Reports
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    • v.53 no.4
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    • pp.191-205
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    • 2020
  • The unexpected pandemic set off by the novel coronavirus 2019 (COVID-19) has caused severe panic among people worldwide. COVID-19 has created havoc, and scientists and physicians are urged to test the efficiency and safety of drugs used to treat this disease. In such a pandemic situation, various steps have been taken by the government to control and prevent the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2). This pandemic situation has forced scientists to rework strategies to combat infectious diseases through drugs, treatment, and control measures. COVID-19 treatment requires both limiting viral multiplication and neutralizing tissue damage induced by an inappropriate immune reaction. Currently, various diagnostic kits to test for COVID-19 are available, and repurposing therapeutics for COVID-19 has shown to be clinically effective. As the global demand for diagnostics and therapeutics continues to rise, it is essential to rapidly develop various algorithms to successfully identify and contain the virus. This review discusses the updates on specimens/samples, recent efficient diagnostics, and therapeutic approaches to control the disease and repurposed drugs mainly focusing on chloroquine/hydroxychloroquine and convalescent plasma (CP). More research is required for further understanding of the influence of diagnostics and therapeutic approaches to develop vaccines and drugs for COVID-19.

A Pipelined Parallel Optimized Design for Convolution-based Non-Cascaded Architecture of JPEG2000 DWT (JPEG2000 이산웨이블릿변환의 컨볼루션기반 non-cascaded 아키텍처를 위한 pipelined parallel 최적화 설계)

  • Lee, Seung-Kwon;Kong, Jin-Hyeung
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.46 no.7
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    • pp.29-38
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    • 2009
  • In this paper, a high performance pipelined computing design of parallel multiplier-temporal buffer-parallel accumulator is present for the convolution-based non-cascaded architecture aiming at the real time Discrete Wavelet Transform(DWT) processing. The convolved multiplication of DWT would be reduced upto 1/4 by utilizing the filter coefficients symmetry and the up/down sampling; and it could be dealt with 3-5 times faster computation by LUT-based DA multiplication of multiple filter coefficients parallelized for product terms with an image data. Further, the reutilization of computed product terms could be achieved by storing in the temporal buffer, which yields the saving of computation as well as dynamic power by 50%. The convolved product terms of image data and filter coefficients are realigned and stored in the temporal buffer for the accumulated addition. Then, the buffer management of parallel aligned storage is carried out for the high speed sequential retrieval of parallel accumulations. The convolved computation is pipelined with parallel multiplier-temporal buffer-parallel accumulation in which the parallelization of temporal buffer and accumulator is optimize, with respect to the performance of parallel DA multiplier, to improve the pipelining performance. The proposed architecture is back-end designed with 0.18um library, which verifies the 30fps throughput of SVGA(800$\times$600) images at 90MHz.

AN EXPERIMENTAL STUDY ON THE CYTOTOXICITY OF CAVITY LINERS (이장재의 세포독성에 관한 실험적 연구)

  • Kim, Jeong-Hye;Kim, Yung-Hai
    • Restorative Dentistry and Endodontics
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    • v.15 no.2
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    • pp.77-92
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    • 1990
  • The purpose of this study was to evaluate the cytotoxic effects of 6 cavity liners in vitro. Human fibroblasts were cultured in ${\alpha}$-MEM and each liner was manually mixed and filled in glass ring cylinder ($8{\times}8mm$ in diameter, in height). The cylinders filled with the liners were placed in the center of the dish (35mm in diameter) containing 3ml of ${\alpha}$-MEM. Millipore filters (pore size $0.22{\mu}m$) to simulate dentin barrier were also placed between the bottom of cylinder and the dish. Then the culture dishes were stored in 5% $CO_2$ containing incubator for 5 and 10 days at the temperature of $36.6^{\circ}C$. The results of the experiments were analyzed by counting the cells in the period of 5 and 10 days respectively, and were assessed by calculating the cell multiplication rate and the relative growth rate. The experiemntal groups and the control group were compared statistically. The results of the study were summarized as follows: 1. The cell number of Zinc oxide-eugenol was $(4.13{\pm}1.31){\times}10^4$ cells/ml at 5 days and $(4.32{\pm}1.61){\times}10^4$ cells/ml at 10 days. 2. The cell number of Cavitec was ($8.35{\pm}2.87{\times}10^4$ cells/ml and $(10.08{\pm}5.10){\times}10^4$ cells/ml at 5 and 10 days respectively. 3. The cell number of Dycal was $(13.56{\pm}3.89){\times}10^4$ cells/ml at 5 days and $(34.75{\pm}8.85){\times}10^4$ cells/ml at 10 days. 4. The cell number of life was $(11.46{\pm}3.32){\times}10^4$ cells/ml and $(21.92{\pm}6.18){\times}10^4$ cells/ml at 5 and 10 days. 5. The cell number of Base cement was $(13.73{\pm}3.73){\times}10^4$ cells/ml and $(36.68{\pm}5.20){\times}10^4$ cells/ml at 5 and 10 days. 6. The cell number of Dentin cement was $(13.58{\pm}3.90){\times}10$ cells/ml and $(66.95{\pm}24.09){\times}10$ cells/ml at 5 and 10 days. 7. The cell multiplication rate of zinc oxide-eugenol cements was significantly less than that of the calcium hydroxide and glass ionomer cement. (P < 0.05)

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A Hardware Implementation of the Underlying Field Arithmetic Processor based on Optimized Unit Operation Components for Elliptic Curve Cryptosystems (타원곡선을 암호시스템에 사용되는 최적단위 연산항을 기반으로 한 기저체 연산기의 하드웨어 구현)

  • Jo, Seong-Je;Kwon, Yong-Jin
    • Journal of KIISE:Computing Practices and Letters
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    • v.8 no.1
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    • pp.88-95
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    • 2002
  • In recent years, the security of hardware and software systems is one of the most essential factor of our safe network community. As elliptic Curve Cryptosystems proposed by N. Koblitz and V. Miller independently in 1985, require fewer bits for the same security as the existing cryptosystems, for example RSA, there is a net reduction in cost size, and time. In this thesis, we propose an efficient hardware architecture of underlying field arithmetic processor for Elliptic Curve Cryptosystems, and a very useful method for implementing the architecture, especially multiplicative inverse operator over GF$GF (2^m)$ onto FPGA and futhermore VLSI, where the method is based on optimized unit operation components. We optimize the arithmetic processor for speed so that it has a resonable number of gates to implement. The proposed architecture could be applied to any finite field $F_{2m}$. According to the simulation result, though the number of gates are increased by a factor of 8.8, the multiplication speed We optimize the arithmetic processor for speed so that it has a resonable number of gates to implement. The proposed architecture could be applied to any finite field $F_{2m}$. According to the simulation result, though the number of gates are increased by a factor of 8.8, the multiplication speed and inversion speed has been improved 150 times, 480 times respectively compared with the thesis presented by Sarwono Sutikno et al. [7]. The designed underlying arithmetic processor can be also applied for implementing other crypto-processor and various finite field applications.

Development History and Direction of On-site Algae Collecting System with Flotation Technology (부상분리 기술을 이용한 현장형 조류수거시스템의 발전 과정 및 개발 방향)

  • Kim, Jong Ik;Han, Ihn Sup;Mei, Qi Wen;Cho, Chong Joo;Jung, Soon Woo
    • Journal of Korean Society of Environmental Engineers
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    • v.39 no.4
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    • pp.194-200
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    • 2017
  • On-site Algae Collecting System (OACS) is one of urgent countermeasures to clean the raw water when the algae blooms severely. Rapid reaction capability, high efficiency and large capacity are required when applying OACS to large water areas. The total performance of OACS are always determined by unit process named Flotation, Trapping and Collection. The working efficiency and daily treatment quantity of OACS can be increased when it runs automatically. As the rapid development of OACS technology, in the first place, equipment are miniaturized and simple. And in the second place, automation process from Trapping to Collection are advanced. So, They produce results higher working efficiency, smaller residual sludge on treated water, system's advanced environmental friendly features and the increased amount of sludge by Collection process to achieve large capacity. Now OACS has overcome the algae multiplication rate to ensured the amount of removal algae. In another aspect, it is high economically feasible because of reducing operation cost against the large capacity.