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Effects of Supplementary Threonine, Canola Oil or Enzyme on Nutrient Digestibility, Performance and Carcass Traits of Growing-finishing Pigs Fed Diets Containing Wheat Distillers Grains with Solubles

  • Thacker, P.A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.12
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    • pp.1676-1685
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    • 2009
  • This trial was conducted to determine the effects of various feed additives on nutrient digestibility, performance and carcass traits of growing-finishing pigs fed diets containing wheat distiller' grains with solubles (WDGS). Seventy-two, individually fed pigs (19.7${\pm}$2.6 kg), were assigned to one of six dietary treatments in a 6${\times}$2 (treatment${\times}$sex) factorial design (N = 12). The control diet was based on wheat and soybean meal while the five experimental diets contained 20% WDGS during the growing period and 12% WDGS during the finishing period. One 20% WDGS diet was unsupplemented while the remaining diets were supplemented with either 0.1% threonine, 5% canola oil, 0.2% enzyme (0.1% Endofeed W containing 1,250 units/g of xylanase and 385 units/g of $\beta$-glucanase and 0.1% Vegpro containing 7,700 HUT/g protease and 75 CMC/g cellulase), or a combination of the three additives at the same levels as those fed separately. The digestibility of dry matter, crude protein and energy were all significantly higher in the control diet than the unsupplemented diet containing 20% WDGS. None of the feed additives improved nutrient digestibility. In addition, none of the additives had any significant effect on gain or feed intake during the growing (19.7 to 43.6) or finishing (43.6 to 114.3 kg) periods or overall (19.7 to 114.3 kg). During the growing period, feed conversion was significantly improved for pigs fed the combination of additives compared with the unsupplemented WDGS diet. During the finishing period and overall, feed conversion was significantly improved for pigs fed 5% canola oil alone or in combination with the other additives. None of the supplements had any effect on carcass traits. These results indicate that WDGS can be successfully used as a partial replacement for soybean meal in diets fed to growingfinishing pigs. However, due to its low energy content, there may be some merit in including high energy ingredients such as canola oil when diets containing WDGS are fed.

Development of Magnetically Separable Immobilized Trypsin (자석에 의해 분리가 가능한 고정화 Trypsin 개발)

  • Ryu, Ji-Soon;Lee, Jung-Heon
    • KSBB Journal
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    • v.23 no.4
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    • pp.350-354
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    • 2008
  • Magnetically separable immobilized trypsin was developed and their biocatalytic activity was evaluated for the different immobilization media. The activity, recyclability, pH effect, and stability of immobilized enzymes were evaluated for the different supporting media. The biocatalytic activity of immobilized trypsin was highest with magnetically separable polyaniline (PAMP), and Vm and Km of PAMP were 0.169 mM/min and 0.263 mM respectively. With increasedpH, the biocatalytic activity increased for all supporting materials used. Immobilized enzymes were recycled and recycle activities were over 90% of their original activity after ten times reuse. The operational stabilities of enzymes were greatly improved with enzyme immobilization.

Preparation and Characterization of PEG-PLA(PLGA) Micelles for Solubilization of Pioglitazone (Pioglitazone 가용화를 위한 PEG-PLA(PLGA) 고분자 미셀의 제조 및 특성분석)

  • Im, Jeong-Hyuk;Lee, Yong-Kyu;Huh, Kang-Moo
    • Polymer(Korea)
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    • v.32 no.2
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    • pp.143-149
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    • 2008
  • We synthesized PEG-PLA (or PLGA) amphiphilic di-block copolymers, which consist of PEG as biocompatible and hydrophilic block and PLA (or PLGA) as biodegradable and hydrophobic block, by ring opening polymerization of LA in the presence of methoxy PEG as a macroinitiator. The compositions and the molecular weights of the copolymers were controlled by changing the feed ratio of LA (and GA) to PEG initiator. The di-block copolymers could self-assemble in aqueous media to form micellar structure. A hydrophobic model drug, pioglitazone, was loaded into the polymer micelle using solid dispersion and dialysis methods, and the drug-loaded micelles were characterized by AFM, DLS and HPLC measurements. The drug loading capacity and in vitro release studies were performed and evaluated under various conditions. These results indicated that the amphiphilic di-block copolymers of PEG-PLA (or PLGA) could solubilize pioglitazone by solid dispersion method and the drug release was modulated according to micellar chemical compositions.

A Study of Architectural Core Planning for Plan Types of General Hospital Wards (국내 종합병원 병동부 평면 유형에 따른 코어 연구)

  • Lee, Hyunjin;Park, Jaeseung
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.18 no.3
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    • pp.41-49
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    • 2012
  • Most large-sized and tall-risen general hospitals of today fairly depend on in-patient wards in designing hospital styles. The core planning for the efficient movements of various people in the words should take into account the sustainable connections between/among the floors, as well as hospital structures and mechanical functions. This study sampled for the study 19 hospital in-patient wards and investigated their flat-core styles. It was found out that hospital structures are changing from symmetrical styles of triangles, quadrangles and rectangles through bending, configuring, transforming to efficient new styles. Symmetrically quadrangled flat-styles are made of multi-cores spread with main an sub-cores. In contrast, symmetrically triangled flat-styles place the open place in the middle in order to prevent from its deepening, and widened the depth line through changing the outdoor top point. Non-symmetrical rectangles minimized the depth value to maintain the recent styles used in the wards, and tended to prefer the transformed styles of quadrangles. The double-corridors easily transshaped from mono corridors reveals the triangled, W-shaped, or Y-shaped figures. The site area ratio of the cores is 11.95% in average. The number of beds which one elevator covers is 66.51 beds in average, and the size of site area which one elevator covers 216.68m. Most cores on the base floor clustered around the average value, with more than 1000 beds shoes 12.83%, does 12.93%, does 14.64%, does 14.58%, which says that the core ratio increases according to hospital beds.

Pretreatment and enzymatic saccharification process of rapeseed straw for production of bioethanol

  • Lee, Heon-Hak;Jeon, Min-Ki;Yoon, Min-Ho
    • Korean Journal of Agricultural Science
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    • v.43 no.4
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    • pp.641-649
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    • 2016
  • This study was conducted to evaluate the yield of bio-ethanol produced by separate hydrolysis and fermentation (SHF) with the pretreated rapeseed straw (RS) using crude enzyme of Cellulomonas flavigena and Saccharomyces cereviase. Crude enzyme of C. flavigena showed enzymatic activity of 14.02 U/mL for CMC 133.40 U/mL, for xylan 15.21 U/mL, for locust gum and 15.73 U/mL for rapeseed straw at pH 5.0 and $40^{\circ}C$, respectively. The hemicellulose contents of RS was estimated to compromise 36.62% of glucan, 43.20% of XMG (xylan + mannan + galactan), and 2.73% of arabinan by HPLC analysis. The recovering ratio of rapeseed straw were investigated to remain only glucan 75.2% after 1% $H_2SO_4$ pretreatment, glucan 45.44% and XMG 32.13% after NaOH, glucan 44.75% and XMG 5.47% after $NH_4OH$, and glucan 41.29% and XMG 41.04% after hot water. Glucan in the pretreatments of RS was saccharified to glucose of 45.42 - 64.81% by crude enzyme of C. flavigena while XMG was made into to xylose + mannose + galactose of 58.46 - 78.59%. Moreover, about 52.88 - 58.06 % of bio-ethanol were obtained from four kinds of saccharified solutions by SHF using S. cerevisiae. Furthermore, NaOH pretreatment was determined to show the highest mass balance, in which 21.22 g of bio-ethanol was produced from 100 g of RS. Conclusively, the utilization of NaOH pretreatment and crude enzyme of Cellulomonas flavigena was estimated to be the best efficient saccharification process for the production of bio-ethanol with rapeseed straw by SHF.

Musculoskeletal Models to Predict Patient-specific Gait Patterns Using Function-based Morphing Technique (기능기반 형상변형기술을 응용한 환자맞춤형 근골격 모델의 보행패턴 예측에 관한 연구)

  • Park, Byoung-Keon;Koo, Bon-Yeol;Park, Eun-Joo;Chae, Jae-Wook;Lee, Soon-Hyuk;Kim, Jae-Jung
    • Korean Journal of Computational Design and Engineering
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    • v.17 no.6
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    • pp.443-455
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    • 2012
  • The configuration of a musculoskeletal (MS) system is closely related to the individual motions of the human body. Many researches have been focused on evaluating the associations between the MS configuration and the individual motion using patient-specific MS models, but it still remains a challenging issue to accurately predict the motion by differed configurations of the MS system. The main objective of this paper is to predict the changes of a patient-specific gait by altering the geometric parameters of the hip joint using function-based morphing method (FBM). FBM is suitable for motion analysis since this method provide a robust way to morph a MS model while preserving the biomechanical functions of the bones. Computed-muscle control technique is used to calculate the muscle excitations to reproduce the targeted motion within a digital MS model without the motion-captured data. We applied this approach to a patient who has an abnormal gait pattern. Results showed that the femoral neck length and the angle significantly affect to the motion especially for the hip abduction angle during gait, and that this approach is suitable for gait prediction.

Static stability and of symmetric and sigmoid functionally graded beam under variable axial load

  • Melaibari, Ammar;Khoshaim, Ahmed B.;Mohamed, Salwa A.;Eltaher, Mohamed A.
    • Steel and Composite Structures
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    • v.35 no.5
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    • pp.671-685
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    • 2020
  • This manuscript presents impacts of gradation of material functions and axial load functions on critical buckling loads and mode shapes of functionally graded (FG) thin and thick beams by using higher order shear deformation theory, for the first time. Volume fractions of metal and ceramic materials are assumed to be distributed through a beam thickness by both sigmoid law and symmetric power functions. Ceramic-metal-ceramic (CMC) and metal-ceramic-metal (MCM) symmetric distributions are proposed relative to mid-plane of the beam structure. The axial compressive load is depicted by constant, linear, and parabolic continuous functions through the axial direction. The equilibrium governing equations are derived by using Hamilton's principles. Numerical differential quadrature method (DQM) is developed to discretize the spatial domain and covert the governing variable coefficients differential equations and boundary conditions to system of algebraic equations. Algebraic equations are formed as a generalized matrix eigenvalue problem, that will be solved to get eigenvalues (buckling loads) and eigenvectors (mode shapes). The proposed model is verified with respectable published work. Numerical results depict influences of gradation function, gradation parameter, axial load function, slenderness ratio and boundary conditions on critical buckling loads and mode-shapes of FG beam structure. It is found that gradation types have different effects on the critical buckling. The proposed model can be effective in analysis and design of structure beam element subject to distributed axial compressive load, such as, spacecraft, nuclear structure, and naval structure.

A Study of Convergence Modem Design for Giga Internet Service over CATV Network (CATV 망에서의 기가 인터넷 서비스를 위한 융복합 모뎀 설계에 관한 연구)

  • Park, Yong-Seo;Lee, Jae-Kyoung
    • Journal of Digital Convergence
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    • v.14 no.10
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    • pp.261-269
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    • 2016
  • This paper aims to propose a novel technology of network convergence to provide ultra high speed internet services over CATV networks, by which a CMC(cable modem concentrator) and CM(cable modem) of 1Gbps level are designed. This technology not only lowers the production cost in comparison to the existing bonding technology with DOCSIS specification but also enables the adjustment of data speed based on the channel bandwidth. According to the experiments, when convolutional code rate with 128QAM is changed to 1/2, 2/3, 3/4 and 7/8, the data recorded the maximum transmission speed of up to 299 Mbps at the zero error rate. As the convolutional code rates with 256QAM is increased, it showed 334Mbps at the error rate of $10^{-5}$. Based on the findings of this paper, if we secure the channel bandwidth of 200MHz and adjust the modulation order of QAM and the convolution code rate depending on the channel status, we can get the transmission speed of more than 1Gbps, which is much more competitive in its function and price than the existing technology based on DOCSIS.

Studies on the Polymeric Surface Active Agent(VI) -The Surface Activities of Anionic Oligomer Surfactant with α-Sulfo Alkanoic Acid- (고분자 계면활성제에 관한 연구(제6보) -알파 술폰 지방산 음이온성 올리고머 계면활성제의 계면성-)

  • Jeong, No-Hee;Park, Sang-Seok;Jeong, Hoan-Kyung;Cho, Kyung-Haeng;Nam, Ki-Dae
    • Applied Chemistry for Engineering
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    • v.4 no.4
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    • pp.683-691
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    • 1993
  • All the activities and physical properties including surface tension, foaming power, foam stability, emulsifying power, dispersion effect, wettability and solubilization of sodium dodecyl polyoxyethylene ${\alpha}$-sulfo alkanoates aqueous solution were measured and critical micelle concentration was evaluated. Their cmc ebaluated by the surface tension method was $10^{-4}{\sim}10^{-5}mol/{\ell}$, and surface tension of the aqueous solution was decreased to 30~70dyne/cm. The experimental results for foaming power, foam stability, emulsifying power in benzene or soybean oil, dispersion effect in calcium carbonate, wettability and solubilization showed a good and efficient surface active properties, and then it would be expected that these products could be applied as O/W type emulsifier, dispersion agent.

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Characterization and Solution Behavior of Polyethylene-based Ionomer Particles in Water (물에서의 폴리에틸렌계 아이오노머 입자 특성과 용액 거동)

  • Yeo, Sang Ihn;Woo, Kyu Whan
    • Journal of the Korean Chemical Society
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    • v.42 no.5
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    • pp.512-518
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    • 1998
  • In this study, various thermodynamic and hydrodynamic parameters characterizing the solution properties of polyethylene ionomer particles in water were determined at $30^{\circ}C$ by means of light scattering and viscosity measurements. Based on the experimental data, we investigated the solution behavior of three kinds of polyethylene ionomers, which are different in composition of the pendant ionic groups of COOK, COOH and $CONH_{2}$, and characterized their particle properties. Ionomers containing 7.6 mol% potassium salt only behave as flexible coils in a relatively good solvent state. On the other hand, two ionomers containing 3.8 mol% amide group together with potassium salt form the compact particles. In addition, the concentration dependence of the effective diffusion coefficient $(D_{eff})$ and the reduced viscosity of the latter ionomers showed the opposite trend from the former, indicating that the composition of the pendant ionic groups have a great influence on the interparticle interaction of ionomers formed in water.

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