• Journal of Preventive Medicine and Public Health
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• v.33 no.1
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• pp.51-55
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• 2000

Objectives . In large-scale field trials, randomization by cluster is frequently used because of the administrative convenience, a desire to reduce the effect of treatment contamination, and the need to avoid ethical issues that might of otherwise arise. Cluster randomization trials are experiments in which intact social unit, e.g., families, schools, cities, rather than independent individuals are randomly allocated to intervention groups. The positive correlation among responses of subjects from the same cluster is in matter in cluster randomization. This thesis is to compare the results of three randomization methods by standard error of estimator of treatment effect. Methods : We simulated cholesterol data varing the size of the cluster and the level of the correlation in clusters and analyzed the effect of cholesterol-lowering agent. Results : In intra-cluster randomization the standard error of the estimator of treatment effect is smallest relative to that in inter-cluster randomization and that in individual randomization. Conclusions : Infra-cluster randomization is the most efficient in its standard error of estimator of treatment effect but other factor should be considered when selecting a specific randomization method.

• The Korean Journal of Applied Statistics
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• v.22 no.2
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• pp.355-364
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• 2009

A simple method is proposed for constructing nonparametric confidence intervals for the difference or ratio of two median failure times. The method applies when clustered survival data with censoring is randomized either (I) under cluster randomization or (II) subunit randomization. This method is simple to calculate and is based on non-parametric density estimation. The proposed method is illustrated with the otology study data and HL-A antigen study data. Moreover, the simulation results are reported for practical sample sizes.

• 대한예방의학회:학술대회논문집
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• 1998.10b
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• pp.227-228
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• 1998

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.7
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• pp.875-880
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• 2019

A RC4 stream cipher is widely used for security applications such as IEEE 802.11 WEP, IEEE 802.11i TKIP and so on, because it can be simply implemented to dedicated circuits and achieve a high-speed encryption. RC4 is also used for systems with limited resources like IoT, but there are performance limitations. RC4 consists of two stages, KSA and PRGA. KSA performs initialization and randomization of S-box and K-box and PRGA produces cipher texts using the randomized S-box. In this paper, we initialize the S-box and K-box in the randomization of the KSA stage to reduce the initialization delay. In the randomization, we use clusters to process swap operation between elements of S-box in parallel and can generate two cipher texts per clock. The proposed RC4 cipher hardware can initialize S-box and K-box without any delay and achieves about 2 times to 6 times improvement in KSA randomization and key stream generation.