• Title/Summary/Keyword: cluster method

Search Result 2,498, Processing Time 0.03 seconds

Development of Anticancer Agents from Korean Medicinal Plants (Part 4). Antitumor Activity of the Butanol Soluble Fraction of Perilla frutescens (한국산 생약으로부터 항암물질의 개발(제4보) 소엽 부탄올 가용분획의 항암활성)

  • 최규은;곽정숙;김영옥;백승화;한두석
    • Toxicological Research
    • /
    • v.13 no.4
    • /
    • pp.311-316
    • /
    • 1997
  • This study was carried out to develop antitumor effect of the n-butanol soluble fraction of Perilla frutescens on (KB cells) human oral epitheloid carcinoma cells. The cytotoxictty of methanollc extract of Perilla frutescens on KB cells was evaluated by 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide(MTT) assay. The antitumor activity of various fractions obtained from n-butanol soluble fraction of Perilla frutescens was evaluated in human oral epithelold carcinoma cells. The antitumor acavity of the n-butanol soluble fraction on human oral epitheloid carcinoma cells was evaluated by MTT assay of colorimetric method. The light microscopic study was carried out to observe morphological changes of cultured human oral epitheloid carcinoma cells. These results were obtained as follows; 1. The fractions 1,2 and 3 of the n-butanol soluble fraction of Perilla frutescens were shown significant antitumor activities. 2. The number of human oral epitheloid carcinoma cells were decreased and tend to form cell cluster by treatment with fractions 1,2,3 and 4 of the n-butanol soluble fraction of Perilla frutescens. 3. The fraction 1 of the n-butanol soluble fraction of Perllla frutescens showed the highest antitumor activity on Perilla frutescens. It has been selected as a lead fraction for further examinations.

  • PDF

A Classification of Luxury Fashion Brands' E-commerce Sites

  • Kim, Sunghee
    • Journal of Fashion Business
    • /
    • v.17 no.6
    • /
    • pp.125-140
    • /
    • 2013
  • The aim of this study was to analyze e-commerce sites of luxury fashion brands in order to provide insights on how to enhance online site quality. For the research, forty-eight components of thirty-one luxury fashion brands' e-commerce sites were investigated during October 2013. For the analysis of clustering e-commerce site components and segmenting e-commerce sites of luxury brands, a hierarchical cluster analysis was applied through using the Ward's method and squared Euclidian distance for binary data. Further, Fisher's exact test was applied in order to distinguish three groups of characteristics in the luxury e-commerce sites. These analyses were carried out by SPSS 21. The result indicated that the components of e-commerce sites were grouped into three categories: basic elements, additional elements and elements of building brand identity. These components were categorized by whether their functions were basic and essential or additional and advanced. The other norm of categorization was related to brand identity. Furthermore, the luxury brands' e-commerce sites were segmented into three groups: a group of endeavoring to promote goods, a group of undistinguished performance, and a group of endeavoring to intensify brand identity. In this segmentation, brand identity or promotional aspects were decisive. Overall, luxury brands were trying to convey their traditional strength through their e-commerce sites. In order to achieve this purpose, brand identity or promotional aspects played an important role.

Verifing Formation of Area of Influence of Subway Station through Land Value Distribution Analysis - Case Study on Seoul

  • Lee, Byoungkil;Lee, Sangkyeong
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
    • /
    • v.34 no.4
    • /
    • pp.403-411
    • /
    • 2016
  • This research has the purpose to develop a method to evaluate whether station’s area of influence has been formed, and verify formation of the area of influence through empirical analysis of all subway stations in Seoul. First, we created buffers of 100m intervals from 100m to 1000m, based on subway station exits, calculated the average land price of each buffer, and divided station areas of influence into 10 clusters using K-means clustering with the average land prices as values of observation. Subsequently, we have assumed a decreasing price curve from increasing distance from a nearby subway station, estimated a price curve and evaluated whether the area of influence actually exists using regression analysis of each cluster. The 10 area of influence clusters were largely divided into strong, weak, and no area of influence of subway station. The stations where the strong areas of influence are formed are mainly located in center, sub-centers, and local centers; stations where weak and no areas of influence are formed are mostly located in the adjacent areas of center or sub-centers or suburbs.

A Study on Store Image Preferences which is Followed by Clothing Buying Motives (II) - As Object of Ewha Womans Student - (의복 구매동기에 따른 점포이미지 선호도에 관한 연구(II) - 이대생을 중심으로 -)

  • Lim, Sook Ja;Lee, Joo Eun
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.17 no.1
    • /
    • pp.3-10
    • /
    • 1993
  • This study intends to provide a beneficial foundation which can aid our understanding of how a clothing consumer group can be classified according to the clothing buying motives, and what differences are there about the importances store image attribute among them and how consumer's preferences to the store image are shown differently among them and ultimately, some concrete data which can be useful in establishing efficient store image strategies for clothing stores. 484 subjects were gathered through convenience sampling method and, for data analysis, cronbach' ${\alpha}$, frequency, percentage, mean, ${\chi}^2$-text, t-test, ANOVA, Duncan Multiple Range Test, Factor Analysis, Cluster Analysis were conducted. the results are as follows; 1. three kind of factors in the clothing buying motives were determined for analysis of consumers group and by which it was revealed as to be significant for us to classify them three subdivisions; those of fashion pursuit group, self display group, financial utilitarian group. 2. Importance on store image attribute was revealed that Ewha students regarded quality, price, more important factors than others. 3. Store image preferences show significantly when concerned with quality, price, fashion, impression and age of store personnel, convenience for exchanging and returning goods, credit, delivery and repair, mailing of catalogue and discount coupon, bightness of store among consumer groups.

  • PDF

QUANTUM EFFICIENCY OF PHOTOGENERATION OF SINGLET OXYGEN FROM THE CLUSTER TYPE OF BINUCLEAR IRON-SULFUR CENTER [2Fe-2S]

  • Choi, Jong-Keun;Kim, Chang-Sook
    • Journal of Photoscience
    • /
    • v.3 no.2
    • /
    • pp.77-83
    • /
    • 1996
  • Photosensitization via the singlet oxygen ($^1O_2$) mechanism by the binuclear iron-sulfur center, denoted as [2Fe-2S], was investigated, using a highly purified ferredoxin (Fd) preparation from spinach leaves. Since the apoprotein of Fd contains a good number of amino acid residues that are readily reactive with $^1O_2$ and thus interfere with the detection of $^1O_2$ generated from [2Fe-2S], we attempted to deprive the $^1O_2$-sensitive residues of their $^1O_2$-scavenging capacity as much as possible by treating Fd with rose bengal plus 550 nm monochromatic light and thereby photooxidatively degrading these residues. The photochemically modified Fd was found to keep the structural integrity of its Fe-S group virtually unaffected by the treatment. By employing chemical trap method for measurement and examining the kinetic effects of azide and deuterium oxide on the reactions of $^1O_2$ with various trap compounds, we were able to demonstrate that [2Fe-2S] indeed acts as a photosensitizer via $^1O_2$. Further, the minimum quantum yield of $^1O_2$ production by [2Fe-2S] was estimated to be 0.0047.

  • PDF

A Study of Attitudes to Changed Health Care Delivery System in a Community (보건의료제도 변화에 대한 지역주민의 수용태도 분석)

  • Yu, Seung-Hum;Sohn, Myong-Sei;Park, Jong-Yeon
    • Journal of Preventive Medicine and Public Health
    • /
    • v.22 no.1 s.25
    • /
    • pp.162-168
    • /
    • 1989
  • This study was conducted to analyse attitudes to a new health care system in a rural community. The specific purpose of this thesis was to classify attitudes to the patient referral system in Kangwha county, and to identify factors affecting the attitudes. Sampling was done by a multi-stage stratified cluster sampling method from the population. The data were collected in Kangwha county through a structured interview survey for two weeks in June, 1957. Attitudes to the patient referral system were classified into four types based upon answers to questions about awareness of the system, the recognition for the necessity of the system, and opinions on the improvement of the system. The four types of attitudes were active acceptance(10.2%), partial acceptance (27.2%), refusal(35.8%), and indifference(26.7%). The respondent's age, educational level, age of head of household, medical insurance fee, the number of ill family members, and the percentage of medical utilization by the family were the variables which affected the attitudes. The medical insurance fee, respondent's age, age of head of household, and the percentage of medical utilization by the family were the statistically significant discriminant factors of the four types of attitudes.

  • PDF

Immunohistochemical study on the insulin-, glucagon-, somatostatin-, and pancreatic polypeptide secreting cells in Korean native goat (한국재래산양 췌장의 insulin, glucagon, somatostatin 및 pancreatic polypeptide 분비세포에 관한 면역조직화학적 연구)

  • Lee, Heungshik S.;Lee, In-se;Kang, Tae-cheon;Kim, Jin-sang;Yi, Seong-joon
    • Korean Journal of Veterinary Research
    • /
    • v.35 no.1
    • /
    • pp.45-54
    • /
    • 1995
  • Pancreatic endocrine cells containing glucagon, insulin, somatostatin and pancreatic polypeptide were identified in the pancreas of the Korean native goat by using immunohistochemical method. Glucagon immunoreative cells were oval or fusiform in shape and located at the periphery of the pancreatic islets. Insulin immunoreactive cells were round or oval in shape and occupied throughout the pancreatic islets except the small area of the periphery. Somatostatin immunoreative cells were oval and elliptical, and mainly located at the periphery of the pancreatic islets. Some of these cells had a cytoplasmic process. Pancreatic polypeptide immunoreactive cells were elliptical or polyhedral and located at the periphery of the pancratic islets where two or more cells formed a cell cluster. The distribution rates of glucagon, insulin, somatostatin and pancreatic polypeptide immunoreactive cells were 24.4%, 44.3%, 13.2% and 18.1% respectively.

  • PDF

Development of the Products Using Jumchihanji( I ) -Classification and Chemical Components, Pulping of Meogujaengi- (줌치한지를 이용한 제품개발(I) -머구쟁이의 분류와 조성분, 펄프화를 중심으로-)

  • Jeon, Chul
    • Journal of Korea Technical Association of The Pulp and Paper Industry
    • /
    • v.35 no.2
    • /
    • pp.58-64
    • /
    • 2003
  • Because of its tendency of making strong Hoc on the fiber surface with fines, Meogujaengi has not been valued as a material of Hanji. As an attempt to manufacture high value-added products using the material made from Jumchihanji, this study performed morphological classification and chemical component analysis and selection of pulping of Meogujaengi method. As a result, it can be concluded as follows, 1. Meogujaengi is assumed to be a local variety of Broussonetia karinoki and its outward appearance is distinguished from Broussonetia kazinoki. 2. The bast fiber of Meogujaengi is longer and thinner than that of Broussonetia papyrifera or Broussonetia kazinoki. However, because of the coarse linear of fiber tissue, there are many clusters. 3. The cluster phenomenon of Meogujaengi is nothing to do with its chemical components. Although the contents of its chemical components are different from those of Broussonetia kazinoki, no component was found that obstructs pulping. 4. The pretreatment for suppressing the occurrence of clusters of Meogujaengi was effective, and it was necessary to do secondary beating using hollander beater after beating mixed with PAM using knife beater.

The Effect of Customer Satisfaction and Customer Loyalty with Relational Benefits on the Internet Shopping Mall (Part I) (인터넷 쇼핑몰에서의 관계혜택이 고객만족도와 고객충성도에 미치는 효과 (제1보))

  • Go, Eun-Ju;Yi, Soo-Kyung;Kim, Seon-Sook
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.33 no.3
    • /
    • pp.467-476
    • /
    • 2009
  • The purpose of this study is to investigate the effect of customer satisfaction and customer loyalty with relational benefits on the Internet shopping mall. For the study, utilizing the convenient sampling method, the sample of study was composed of female and male adults aged between 20 and 30 living in Seoul metropolitan area who had experienced purchase of fashion products on the web. Of 350 distributed, 311 useful questionnaires were returned. The survey research design was employed with structured questionnaire. For data analysis, descriptive statistics, factor analysis, reliability analysis, cluster analysis and multiple- regression analysis were used. The results of this study are as follows: Psychological benefits had higher influence than other relational benefits(social benefits, customization benefits, economic benefits) on the both customer satisfaction and customer loyalty positively. There was a high relationship between the customer satisfaction and the customer loyalty. The customer satisfaction had a positive influence on the customer loyalty. And social benefits had the least influence among the sub-factors of relational benefits on the customer satisfaction. Also, customization benefits had the least influence among the sub-factors of relational benefits on the customer loyalty.

Optimal Selection of Fuel Bias and Propellant Residual Analysis of a Liquid Rocket (액체 추진 로켓의 최적 연료 바이어스 산정 및 추진제 잔류량 분석)

  • Song, Eun-Jung;Cho, Sangbum;Roh, Woong-Rae
    • Journal of the Korean Society for Aeronautical & Space Sciences
    • /
    • v.43 no.1
    • /
    • pp.88-95
    • /
    • 2015
  • This paper considers the effects of propellant mixture ratio and loading errors on the performance of a liquid rocket. Propellant residuals generated by error sources are analyzed for a launch vehicle model whose first stage consists of a cluster rocket of four 75-tonf class engines using a statistical Monte-Carlo approach and then the optimal fuel biases minimizing residuals are computed. The results are validated through comparison with analytic method using approximate formula, which have been applied for other space launch vehicles.