• Title/Summary/Keyword: clonogeinic assay

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Anticancer Effect of Hydrophobic Protein Fraction from Red Ginseng by Clonogenic Assay (Clonogenic Assay에 의한 홍삼 소수성단백질 분획의 항암효과)

  • Kim, Chang-Han;Lee, Myung-Sub;Lee, Kyung-Ho
    • Journal of Ginseng Research
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    • v.19 no.1
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    • pp.27-30
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    • 1995
  • We established the model of clonogenic assay with cancer cell lines such as SW-156(kidney), SNU-5(stomach), Hep G2(liver), and WiDr(colon), and we investigated anticancer effect of hydrophobic protein fraction(N-fraction) from Korea red ginseng by using this model. The results of clonogenic assay showed that N-fraction had anticancer activity against SNU-5 above 100 $0.2\mu\textrm{g}$/ml concentration, and did not exhibit anticancer activity against cell lines such as SW-156, WiDr, and Hep G2 up to 1,000 $\mu\textrm{g}$/ml concentration. This result suggests that N-fraction has specially anti-stomach cancerous effect.

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