• Title/Summary/Keyword: clinical scales

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Evaluation of Clinical Efficacy and Safety Following Kyungokgo-Gamibang Administration in Dogs with Skin and Joint Diseases

  • Ga-Won Lee;Heyong-Seok Kim;Jong-Won Kim;Yang-Seon Moon;Chang-Su Na
    • Journal of Veterinary Clinics
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    • v.40 no.2
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    • pp.113-118
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    • 2023
  • Skin and joint diseases are relatively common in dogs. Nutritional complementation is one of the various management strategies for these disorders. This study evaluated the safety and clinical efficacy of Kyungokgo-gamibang in dogs with skin and joint diseases. Thirty dogs with diseases were included and divided into three groups: control group (n = 15), skin group (n = 10), and joint group (n = 5). The skin and joint groups were fed skin and joint gums composed of Kyungokgo-gamibang extract with standard treatment for four weeks. The control group included dogs with skin diseases who were administered standard skin infection treatment for 4 weeks. The physical and laboratory results showed no remarkable adverse effects of Kyungokgo-gamibang extract after its administration in dogs. Clinical efficacy was evaluated using quality of life scale, and levels of cytokines, including interferon-γ, interleukin (IL)-2, IL-6, IL-8, IL-10, monocyte chemoattractant protein-1, and tumor necrosis factor-α, for 4 weeks in all groups. Dermatologic clinical scales were performed for 4 weeks in the control and skin groups. Both the control and skin groups had significantly decreased dermatologic clinical scales, including pruritus and erythema scales (p < 0.05). Among the cytokine levels, only IL-2 concentration was significantly decreased in the skin group after 4 weeks of administration of the Kyungokgo-gamibang extract (p = 0.032). There was no significant difference between the levels of cytokines on days 0 and 28 in the joint group. The quality of life scale was significantly increased after week 4 compared to week 0 in the skin (p = 0.008) and joint groups (p = 0.041). This study suggests that Kyungokgo-gamibang extract can be applied in managing dogs affected by skin and joint diseases without adverse effects.

An Introduction to Luria-Nebraska Neuropsychological Battery (Luria-Nebraska 신경심리검사의 소개)

  • Kim, Young-Chul
    • Sleep Medicine and Psychophysiology
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    • v.1 no.1
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    • pp.29-35
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    • 1994
  • Overall purposes of neuropsychological tests are summarized as follows: 1) Indentifying brain damage in individuals who have symptoms of uncertain etiology; 2) Assessing the extent and nature of deficits for forensic purposes and planning appropriate intervention; 3) Evaluating the effects of intervention or rehabilitation; 4) Examining the effects of various types of brain damage across different populations; and 5) Testing theoretical propositions about brain-behavior relationship. Of the neuropsychological tests, the Luria-Nebraska Neuropsychological Battery(LNNB) is easily transportable, relatively inexpensive, and performable by trained technician. The Korean version of LNNB is now being designed and will be used clinically in the near future. Localization and equipotential theories of brain function had been prevalent until Luria's theory of brain function. Brain, composed of three brain units in the theory, is the functional system in which each brain area has specific function and produce the function-related behavior. LNNB consists of 11 clinical scales, 5 summary scales, 8 localization scales, and 28 factor scales.

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Cognitive Behavioral Therapy in Childhood Tic Disorder : A Case of Report (틱 장애 아동의 인지행동치료 증례: 5회기 습관뒤집기 훈련과 호흡훈련을 중심으로)

  • Song, Jung-Rim;Hong, Jong-Woo;Doh, Jin-Ah;Kim, Hyun-Woo;Lim, Myung-Ho
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.22 no.1
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    • pp.38-43
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    • 2011
  • Chronic tic disorder or Tourette syndrome is known to be a chronic neuro-behavioral disease for which cognitive behavioral therapy (CBT) strategies have recently been introduced. Here, we report the effectiveness of CBT in a case of childhood chronic tic disorder, which is very common in clinical settings. The DSM-IV clinical diagnosis was applied by a child psychiatrist. The Yale Global Tic Severity Scale, Kovac's children's depression inventory, Spielberger State-Trait Anxiety Inventory, Abbreviated Conners' Rating Scales, and the Dupaul ADHD Rating Scales were used. This case involved a pharmacological treatment-refractory patient over the previous year. Thus, psychiatric consultation was undertaken. Subsequently, we administered five sessions of CBT for four weeks, consisting of symptom evaluation and planning, habit reversal training, and ventilation training. Following four weeks of CBT administration, there were improvements in the scores of the Yale Global Tic Severity Scale and the Clinical Global Improvement scale. Our observations indicate that CBT may be effective in the treatment of childhood tic disorder.

Recent Trend and Proposal for Acupuncture Clinical Trial on Atopic Dermatitis (침술과 관련된 아토피 피부염 임상연구의 최근 동향 분석 및 제언)

  • Lee, Sung-Eun;Yoon, Hwa-Jung;Ko, Woo-Shin
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.30 no.3
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    • pp.76-87
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    • 2017
  • Objectives : This study aimed to analyze the recent acupuncture clinical trial on atopic dermatitis and to suggest the plan about how to improve its quality. Methods : Data were collected through electronic database including MEDLINE. We set up the search terms for "atopic dermatitis AND acupuncture" and limited period of data within 6 years and type for RCT(Randomized Clinical Trial), SR(Systemic Review). Results : Total 5 studies were selected. Two were RCTs, and the rest were SRs. RCTs were insufficient about acupoint selection criteria and foundation. SRs both pointed out that systematic clinical trial is required. Conclusions : Based on these, we suggested the plan as follows. 1. Selection criteria - We should reevalute the participants by using diagnostic criteria and scales. 2. Selection acupoints - We should present the foundation that why we choose these acupoints. 3. Establishing acupuncture and control group - We should make control group clearly after calculating the number of participants statistically. 4. Blinding - We should propse the method, type, procedure and evaluation about randomization. 5. Evaluation scale - We should select the suitable scales for research objectives.

Acupuncture as an Additional Method of Rehabilitation Post-COVID-19: a randomized controlled trial

  • Indira Omarova;Assiya Akanova;Almagul Kurmanova;Gaukhar Kurmanova;Natalya Glushkova;Amina Seidanova;Kuatzhan Turysbekov
    • Journal of Pharmacopuncture
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    • v.26 no.3
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    • pp.238-246
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    • 2023
  • Objectives: The purpose of this study was to evaluate the effectiveness of complex rehabilitation with and without acupuncture in a hospital setting. Methods: A randomized clinical trial was performed at Rehabilitation center "Kamenskoe Plato" in Almaty, Kazakhstan. 160 patients with Post COVID-19 condition were randomly equally divided into an acupuncture with complex rehabilitation methods and a only complex rehabilitation methods group in the period from March 1, 2022 to July 1, 2022. Either groups was performed for an 10-14 days period. The outcome measures were the Bartel index, the Borg scale, Modified Dyspnea Scale and the 6-minute walking test. Adverse events also were monitored and documented. Results: We found statistically significant improvement after the rehabilitation course with acupuncture in the all scales. And in the group without acupuncture, only on two scales: MDS and Borg scale. Conclusion: Rehabilitation with acupuncture is possible and effective in patients recovering from post-COVID-19. Our findings may be useful to guide clinicians taking care of patients with post-COVID-19.

Study on MMPI-2 Profile of Adults with Internet Addiction (성인 인터넷 중독위험군의 MMPI-2 프로파일 연구)

  • Seo, Bo-Kyung;Lee, Seong-Hee
    • The Journal of the Korea Contents Association
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    • v.17 no.3
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    • pp.88-99
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    • 2017
  • This study investigated the clinical characteristics of the Internet addiction risk group using MMPI-2 and discussed whether the MMPI-2 can be used for diagnosis, evaluation and intervention of the Internet addiction risk group. We verified the difference in the MMPI-2 scales between the addiction-risk group and the general user group, and verified whether the substance-related scales MAC-R, AAP, and AAS scales can distinguish between Internet addiction risk group and general users. The results of the analysis of the MMPI-2 characteristics of 39 Internet addiction risk group and 21 general user group who visited internet addiction counseling center showed significant difference in the D, Pa, Pt, Sc, and Si scales on the clinical scale. There was no difference in the MAC-R, AAS, and APS scales between the Internet addiction group and the general user group. This suggests, that it is not possible to screen the Internet addiction risk group with the supplementary measure, and it is necessary to develop a new scale to diagnose internet addiction.

A Study of the Relationship of the CSEI (The Core Seven-Emotions Inventory) and MMPI-2 (Minnesota Multiphasic Personality Inventory-2) (핵심감정척도와 다면성 인성검사의 상관성연구)

  • Heo, Eun-Jung;Lee, Ga-Won;Lee, Na-Hyun;Cheong, Moon-Ju;Lyu, Yeoung-Su;Kang, Hyung-Won
    • Journal of Oriental Neuropsychiatry
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    • v.30 no.3
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    • pp.153-164
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    • 2019
  • Objectives: The purpose of this study was to examine the correlation between CSEI (The Core Seven-Emotions Inventory) and MMPI-2 (Minnesota Multiphasic Personality Inventory-2). Methods: We analyzed the correlation between students' demographic characteristics, blood type, MMPI-2, and CSEI using the SPSS (Statistical Package for the Social Science) 24.0. Descriptive Statistical Analysis, independent t-test, analysis of variance (ANOVA), subsequent analysis duncan (post hoc multiple comparison), and correlation analysis were conducted. Results: 1. According to the demographic characteristics of 91 participants in this study: 60 males (65.9%), 88 unmarried (96.7%), 58 without religion (63.7%), 54 who have experienced stress in the last three months (59.4%), and 82 in their 20s (90.1%) comprised the majority. 2. As a result of verifying correlation by subfactors of CSEI, Hui (喜) showed statistically significant negative correlation with U (憂), Bi (悲), and Gong (恐). Six emotions except Hui (喜) showed statistically significant positive correlation, except for the relationship between U (憂) and Kyeong (驚). 3. Hui (喜) of CSEI had negative correlation with eight factors of MMPI-2 Clinical Scales except Pa (Paranoia) and Ma (Hypomania), whereas Bi (悲) had positive correlation with nine factors of MMPI-2 clinical scales except Mf (Masculinity-Femininity). Sa (思), Bi (悲), and Gong (恐) had similar tendency of positive correlation with six factors of MMPI-2 Restructured Clinical Scales. Conclusions: Based on the above results, we concluded that CSEI's sub factors had consistent correlations with MMPI-2. Thus, CSEI could contribute to psychiatry clinical use.

Clinical Utility of the Minnesota Multiphasic Personality Inventory-Adolescent Restructured Form in the Assessment of Internalizing and Externalizing Disorders in Adolescents: A Preliminary Approach

  • Hye Ji Yun;Eun Hee Park;Hyun Ju Hong
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.34 no.4
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    • pp.268-274
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    • 2023
  • Objectives: This study investigated whether the Minnesota Multiphasic Personality Inventory-Adolescent Restructured Form (MMPI-ARF) can differentiate between two groups of adolescents, one diagnosed with internalizing disorders and another with externalizing disorders, and examined the clinical utility of the MMPI-A-RF by examining which subscales can significantly discriminate between these two groups. Methods: A total of 105 adolescents aged 13-18 years completed the MMPI-A-RF (53 internalizing disorder and 52 externalizing disorder groups). Independent t-test, chi-square test (χ2), and discriminant analysis were used to examine whether MMPI-A-RF can distinguish between the two groups. Results: Sixteen MMPI-A-RF scales best predicted differences between the groups with internalizing and externalizing disorders. Fourteen scales (Higher-Order Scale [Emotional/Internalizing Dysfunction], Restructured Clinical [RC] Scale [RC demoralization, Somatic Complaints (RC1), and Low Positive Emotions (RC2)], Personality Psychopathology Five Scale [Introversion/Low Positive Emotionality-Revised, Negative Emotionality/Neuroticism-Revised], Somatic/Cognitive Scale [Malaise, Head Pain Complaints, and Gastrointestinal Complaints], Internalizing Scale [Stress/Worry, Self-Doubt], Externalizing Scale [Negative School Attitudes], Interpersonal Scale [Social Avoidance, Shyness]) were associated with the internalizing disorder group, whereas two scales (Externalizing Scale [Conduct Problems, Negative Peer Influence]) were associated with the externalizing disorder group. Conclusion: The MMPI-A-RF can be an efficient assessment tool for a quick diagnosis as it can classify individuals with internalizing and externalizing disorders in clinical settings that lack a variety of assessment tools for children and adolescents.

The Clinical and Psychological Characteristics of the Patients with Temporomandibular Disorders according to Its Diagnostic Subgroups (진단분류에 따른 측두하악장애 환자의 임상적 및 심리적 특징)

  • 김정호;기우천;최재갑
    • Journal of Oral Medicine and Pain
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    • v.22 no.1
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    • pp.45-63
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    • 1997
  • A Study was conducted to examine the nature and extent of psychological differences among diagnostic subgroups of temporomandibular disorders(TMD) patients and to whether psychological distress acts as a precipitator for TMD or is only an incidental consequence of the discomfort and frustrations presented by the disorder. Ninty six TMD patients and ninty seven non-TMD dental patients were included for the study as an experimental group and control group. TMD patients were classified into subgroups according to their primary pain sites and labeled as: 1) Myogenous TMD group; 2) Arthrogenous TMD group; 3) Mixed TMD group. After Hilkimo indices were rated from patient history and clinical examination, levels of psychological distress were measured using SRRS (Social Readjustment Rating Scale) and MMPI (Minnesota Multiphasic Personality Inventory). Outcomes from Helkimo indices, SRRS, and MMPI were assessed in terms of diagnostic subgroups and pain chronicity. The relationship between SRRS and MMPI scores were also assessed. The results were as follows : 1. The TMD patients showed higher frequencies of AiII, DiII, and DiIII of Helkimo indices than those in the control subjects. 2. The chronic TMD patients showed lower frequencies of DiII and DiIII of Helkimo indices than those in the acute group. 3. The arthrogenous TMD group showed higher frequencies of DiII and DiIII of Helkimo indices than those in the myogenous TMD group. 4. The TMD patients showed higher SRRS mean score than that in the non-TMD patients. 5. The SRRS mean score was highest in the myogenous TMD group and lowest in the arthrogenous TMD group. 6. The chronic TMD patients showed higher SRRS mean score than the acute TMD group. 7. The TMD patients showed higher MMPI mean scores on the Hs, D, Hy, and Pt scales than those in the non-TMD patients. 8. The MMPI mean scores on th Hs, D, and Hy scales were higher than of other MMPI scales in the TMD patients as well as in the myogenous and the mixed TMD group and they showed 1-3-2(Hs, -Hy, -D.) profile pattern, conversion "V". 9. The MMPI mean scores on the Hs and Hy scales were higher in all subgroups of TMD patients than non-TMD patients. 10. Although there were no significant differences in the MMPI mean scores on all the scales between the acute and the chronic groups of all TMD patients, the chronic myogenous TMD group showed higher MMPI mean scores on the Hs, Hy, Pa, and Pt scales than the acute myogenous TMD group. 11. There were positive correlationships between SRRS score and each MMPI scores on the Hs and Hy scales.Hy scales.

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