• Journal of Haehwa Medicine
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• v.23 no.1
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• pp.13-20
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• 2014

Objectives : Clinical data in traditional medicine, such as Korean medicine, traditional Chinese medicine have a long history of accumulating evidence and these rich data are recorded in classic literature. We have conducted a study of developing an algorithm that support clinical diagnosis with composing both users knowledge and data obtained from literature. In order to define necessary information and required steps in diagnosis procedure, we have established a clinical diagnostic procedure including a step of collecting patients symptoms, a step of determining candidates, a step of diagnostic decisions, a step of deciding of treatment and a step of adjusting medicinal treatment. Methods : Our study have been based on the following premises. 1. Using data obtained from literature contributes to accurate diagnosis 2. Displaying the data before users request contributes to accurate conclusion. Displaying before users request enable users to recognize their overlooking a fact on purpose or not. 3. Checking symptoms that are commonly accompanied with a group of diseases that accompany symptoms appealed by a patient contributes to accurate conclusion. These symptoms are worthy of checking. 4. Comparing more than two candidates contributes to accurate conclusion. Users can compare their accompanied symptoms with patients symptoms and this helps users to make a decision. Results : Based on the above premises, we have developed an literature based algorithm to provide various functions, such as recommending symptoms to check, comparing groups of symptoms, differential diagnosis, recommending medicinal materials to prescribe, and more. Conclusions : By the results of simulation with virtual diagnostic scenario, we concluded this algorithm is useful helping clinician in diagnosis procedure.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.12 no.1
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• pp.80-92
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• 2008

Background: The consequences of disordered breathing patterns are not only distressing to the patient but also expensive to our health care systems if they are not diagnosed and treated. So we performed this study to investigate clinical significants trough gigong, yoga and hyperventilation in oriental medicine and westen medicine Objective: To review the relationship of electrogastrography with autonomic nervous system and to study its clinical application. Method: We investigate the research results through internet search engine, Pubmed. Conclusion: Electrogastrography is a reliable, non-invasive method for recording gastric myoelectrical activity and is used for objectification of diagnosis related to gastric peristalsis. Gastric myoelectrical activity seem to involve autonomic nervous system, especially parasympathetic nervous system. The study should be continuing about relationship between electrogastrography and autonomic nervous system.

• Korean Journal of Radiology
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• v.23 no.5
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• pp.495-499
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• 2022

• Clinical Endoscopy
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• v.55 no.5
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• pp.701-702
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• 2022

• The Journal of the Society of Korean Medicine Diagnostics
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• v.9 no.1
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• pp.98-111
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• 2005

Background and purpose: The Han(cold)-Yol(heat) patternization is one of the most usually used diagnostic methods in oriental medicine. This is preceding studies for compensating questionnaries on Han-Yol that were made by sook-kyeng Kim. Methods: Questionnaries on Han-Yol that will be worked out should be useful for clinical examination. So We selected symptoms based on Donguibogam that is regarded as a clinical textbook in Korea. Results: It is expected that not only Sil-Yol but also Hu-Yol and Yol combined with Han can be diagnosed by new questionnaries. Conclusion: These symptoms based on Donguibogam will be made into questionnaries that can diagnose not only Sil-Yol but also Hu-Yol and Yol combined with Han.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.13 no.1
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• pp.54-64
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• 2009

Background and purpose : We previously developed questionnaire of Yukmijiwhang-tang symptom on the Delphi method. But developed a questionnaire was not verified in the clinical. So, to ensure objectivity, quantification and validity, verification is needed for questionnaire items before applying a clinical. On this study, we looked at whether questionnaire items had been validity in the clinical. Methods : The previously developed questionnaire of Yukmijiwhang-tang symptom was applied to 200 patients who visited 12 local oriental medicine clinics. Item data were analyzed by factor analysis and reliability test. Results : The developed questionnaire showed remarkable reliability.(Cronbach's $\alpha$=0.869) In factor analysis, items were clustered to 6 factors. Conclusions : The results of this study indicate that the developed quetionnaire is reliable and valid for Yukmijiwhang-tang symptom. It can be used to evaluate Yukmijiwhang-tang symptom objectively.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.237-237
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• 2002

Creatine phosphokinase (CPK) was a marker in diagnosis of rhabdomyolysis. The CPK abnormality could be induced by intake of HMG CoA reductase inhibitors (statins). The objective of this study was to estimate the incidence rate of CPK abnormality by each statin. (omitted)

• Genomics & Informatics
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• v.3 no.3
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• pp.68-73
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• 2005

Pharmacogenomics research requires an intelligent integration of large-scale genomic and clinical data with public and private knowledge resources. We developed a web-based knowledge base for KPRN (Korea Pharmacogenomics Research Network, http://kprn.snubi. org/). Four major types of information is integrated; genetic variation, drug information, disease information, and literature annotation. Eighteen Korean pharmacogenomics research groups in collaboration have submitted 859 genotype data sets for 91 disease-related genes. Integrative analysis and visualization of the large collection of data supported by integrated biomedical path­ways and ontology resources are provided with a user-friendly interface and visualization engine empowered by Generic Genome Browser.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2005.09a
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• pp.366-370
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• 2005

Tissue microarry is one of the high throughput technologies in the post-genomic era. Using tissue microarray, the researchers are able to investigate large amount of gene expressions at the level of DNA, RNA, and protein The important aspect of tissue microarry is its ability to assess a lot of biomarkers which have been used in clinical practice. To manipulate the categorical data of tissue microarray, we applied Bayesian network classifier algorithm. We identified that Bayesian network classifier algorithm could analyze tissue microarray data and integrating prior knowledge about gastric cancer could achieve better performance result. The results showed that relevant integration of prior knowledge promote the prediction accuracy of survival status of the immunohistochemical tissue microarray data of 18 tumor suppressor genes. In conclusion, the application of Bayesian network classifier seemed appropriate for the analysis of the tissue microarray data with clinical information.

• Korean Journal of Adult Nursing
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• v.20 no.3
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• pp.470-480
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• 2008

Purpose: The purpose of this study was to validate the scale of Informatics Competencies for Nurses developed by Staggers, Gassert & Curran(2001) among Korean nurses. Methods: The subjects of this study were 58 RN-BSN students and 314 nurses in Busan, Ulsan and Kyoungnam province. Data were collected by questionnaires from June to August, 2006 and from October, 2006 to August, 2007 and were analyzed by Principal Component Analysis for construct validity and Cronbach's ${\alpha}$ coefficient for reliability. Results: A factor analysis was conducted and 30 items that had a factor loading more than .40 were extracted. The explained variance from 5 factors was 55.33% of the total variance. The factors were named 'basic computer usage', 'medical informatics-related software usage', 'computer related information management', 'perception of informatics', and 'information search using internet'. The first factor consisted 10 items which explained 29.89% of the total variance and the second factor contained 7 items. The Cronbach's ${\alpha}$ coefficient was .91 among the 30 items. Conclusion: This scale, Informatics Competencies for Nurses, was proved as a proper instrument to apply to Korean nurses.