• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2003.05a
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• pp.448-451
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• 2003

This study describes a new maskless nano-fabrication technique of Si (100) using the combination of nanometer-scale mechanical forming by nano-indenter XP and KOH wet etching. First the surface of a Si (100) specimen was machined by using the nano-machining system, which utilizes the mechanism of the nano-indenter XP. Next, the specimen was etched by KOH solution. After the etching process, the convex structure or deeper hole is made because of masking or promotion effect of the affected layer generated by nano-machining. On the basis of this interesting fact, some sample structures were fabricated.

• Journal of electromagnetic engineering and science
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• v.18 no.3
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• pp.182-187
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• 2018

A low profile asymmetrical fractal boundary patch antenna based on reactive impedance surface (RIS) and a mushroom unit cell (MUC) is proposed and studied for dual band operation. The sides of the square patch antenna are replaced with asymmetrical half circled fractal curves for circular polarization operation at patch mode band. The fractal patch antenna is loaded with MUC for dual band operation. The antenna radiation characteristics are investigated and illustrated with both simulated and experimental results in detail. The 10-dB return loss bandwidth are 8.48% (3.21-3.49 GHz) and 2.59% (2.30-2.36 GHz) at upper and lower resonance frequencies, respectively. The 3-dB axial ratio bandwidth is 4.26% (3.21-3.35 GHz). A close agreement between simulation data with experimental results is observed.

• Proceedings of the Korean Society of Agricultural Engineers Conference
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• 2000.10a
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• pp.507-512
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• 2000

The main objective of this study is to provide a soil surface information, which represent a soil reflectance spectrum, by remote sensing technology. The soil reflectance of the soil was measured using a spectroradiometer in the wavelength range from 300nm to 1100nm. Measurements of soil reflectance have been made in four different soils. The results suggest that the reflectance properties of soils are related to their mineral composition and soil moisture. Increasing soil moisture resulted in an decrease in the rate of reflectance which leads to parallel curves of soil reflectance spectra. The soil line representing the relationship between red and near-infrared soil reflectance is characterized by soil types.

• Proceedings of the Korean Society of Agricultural Engineers Conference
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• 2000.10a
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• pp.525-530
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• 2000

The loss of soil and nutrients from land surfaces to surface water supplies continues to be an important source of nonpoint source pollution. This study was initiate to develop an empirical relationship among the contaminants. SS, COD, T-N, and T-P were collected from agricultural surface water quality studies carried out in Hwasung-Gun, Kyonggi-Do. Correlation analysis, regression analysis, and reliability analysis were conducted. The regression equations were developed between SS and COD, SS and T-P, COD and T-P, and the resulting r$\^$2/ value was over 0.78. The regression equation enables a reasonable prediction of phosphorus concentration and COD concentration for known suspended solid concentration.

• Archives of Pharmacal Research
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• v.21 no.6
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• pp.645-650
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• 1998

The dual drug-loaded alginate beads simultaneously containing drug in inner and outer layers were prepared by dropping plain (single-layered) alginate beads into $CaCl_2$ solution. The release characteristics were evaluated in simulated gastric fluid for 2 h followed by intestinal fluids thereafter for 12 h. The surface morphology and cross section of dual drug-loaded alginate beads was also investigated using scanning electron microscope (SEM). The poorlv water-soluble ibuprofen was chosen as a model drug. The surface of single-layered and dual drug-loaded alginate beads showed very crude and roughness, showing aggregated particles, surface cracks and rough crystals. The thickness of dual drug-loaded alginate beads surrounded by outer layer was ranged from about 57 to 329mcm. The distinct chasm between inner and outer layers was also observed. In case of single-layered alginate bead, the drug was not released in gastric fluid but was largely released in intestinal fluid. However, the release rate decreased as the reinforcing $Eudragit^{\circledR}$ polymer contents increased. When the plasticizers were added into polymer, the release rate largely decreased. The release rate of dual drug-loaded alginate beads was stable in gastric fluid for 2 h but largely increased when switched in intestinal fluid. The drug linearly released for 4 h followed by another linear release thereafter, showing a distinct biphasic release characteristics. There was a difference in the release profiles between single-layered and dual drug-loaded alginate beads due to their structural shape. However, this biphasic release profiles were modified by varying formulation compositions of inner and outer layer of alginate beads. The release rate of dual drug-loaded alginate beads slightly decreased when the outer layer was reinforced with $Eudragit^{\circledR}$ RS1OO polymers. In case of dual drug-loaded alginate beads with polymer-reinforced outer layer only, the initial amount of druc released was low but the initial release rate (slope) was higher due to more swellable inner cores when compared to polymer-reinforced inner cores. The current dual drug-loaded alginate beads may be used to deliver the drugs in a time dependent manner.

• Journal of Pharmaceutical Investigation
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• v.33 no.3
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• pp.179-185
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• 2003

Melatonin (MT) is an indole amide pineal hormone. It has not only very short half-life but also pH-sensitive property. The sustained release dosage form which delivers MT in a circadian fashion over 8 h is clinical value. The purpose of this study is to prepare sugar beads using multiple coating methods and enteric-coated in a sustained release to evaluate in vitro release characteristics in simulated gastric and intestinal fluids. The $Eudragit^{\circledR}$ as a polymer, sustained release membrane, and triethylcitrate (TEC) as a plasticzer were used. Multi-coated melatonin delivery system was composed of sugar, various excipients, $Eudragit^{\circledR}$ and enteric materials (e.g. hydroxy propyl methyl cellulose phthalate, HPMCP), and prepared by fluid bed coater. The dissolution test was carried out using the basket method at a stirring speed of 100 rpm at $37^{\circ}C$ in simulated gastric (pH 1.2) and intestinal fluid (pH 7.4). The released amount of MT was determined by High performance liquid chromatography method. The morhologies of surface and cross section of multi-coated beads were observed by scanning electron microscope. Size of multi-coated sugar beads was ranged over $1000{\sim}1300\;{\mu}m$. The release rate of MT from coated beads was limited in simulated gastric fluid (pH 1.2), but it was sustained in intestinal fluid (pH 7.4) during $3{\sim}8$ hours. The MT beads may provide small-intestine-targeted device for oral delivery. Studies on animal and relative experiment are in process.

• Proceedings of the Korean Society of Agricultural Engineers Conference
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• 2000.10a
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• pp.108-113
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• 2000

A field study was performed to investigate the effect of water saving irrigation method on water use efficiency and rice yield. The field plot was 40a (40 ${\times}$ 100m) in size and located at Buryangmyun, Kimjae city, Chonbuk province. Field measurements were made during the growing seasons, May to September of the year 1998 and 1990. Irrigation water volume, drainage water volume, rainfall and ponding depth were measured. Irrigation water management practice employed was such that to keep the ponding depth about 3 to 4cm by intermittent irrigation with drying the soil surface until hair cracks emerge before the next irrigation. The amounts of water volume irrigated and drained were measured by pipe flow meter and ponding depth was observed by using a partly buried 120mm diameter PVC pipe. The results showed that the irrigation water depths, the rainfalls, and the drainage depths were 379mm, 458mm, and 448mm in 1988, and 274mm, 819mm, and 736mm in 1990, respectively. The average yield was 590kg per 10a. The water saving irrigation method saved irrigation water by about 20% with higher yield compared with the traditional method.

• Proceedings of the Korean Society of Agricultural Engineers Conference
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• 2000.10a
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• pp.550-556
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• 2000

Three floating islands were constructed on the surface of the reservoir, each consisting of 10 16-㎡ (4${\times}$4 m) segments, made of wood frames and floats. Three species of aquatic macrophytes were planted in each island on June, 1998. Phragmites australis was considered as the suitable aquatic macrophyte for the floating islands since it maintained the most efficient root and shoot balance among the macrophytes. The net primary productivity of P. Australis was 3,604 g/㎡ based on dry weight in 1999, with uptake rates of nitrogen and phosphorus estimated at 77.4 g/㎡/yr and 5.7 g/㎡/yr, respectively. The result of water quality simulation for the floating islands showed that, through adsorption of nutrients and light screening, they could reduce the amount of phytoplankton, thereby decreasing COD concentration.

• The Journal of Korean Academy of Prosthodontics
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• v.44 no.5
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• pp.606-616
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• 2006

Purpose: This experiment examined the effect of different surface treatment on the osseointegration and stability of implants. Material and methods: In this study, 40 each of machined, SLA and RBM implants, which are the most commonly used implants, were implanted into the tibia of 20 normal rabbits using $OsseoCare^{TM}$. The rabbits were sacrificed after 1 week, 4 weeks, 8 weeks and 12 weeks for implant stability analysis, removal torque analysis, histologic and histomorphometric analysis. Result : ISQ showed significant difference between Machined and RBM at first week and at 4 weeks. There was significant difference between Machined and both SLA and RBM(p<0.05) but after 8 weeks there were no significant difference between each group. In the removal torque, RBM showd significantly higher values than SLA and Machined surface at 1st week. At 4th and 12th week, there was significant difference between Machined and SLA, RBM(p<0.05). In the bone to implant contact variable, there was no significant difference between each surface treatment method. In the Machined surface group, there was no significant difference between each time interval. but in SLA group, there were significant differences between the 1st week and 12th week and in RBM group, there were significant differences between the 1st week and 8th, 12th week and between 4th and 12th week(p<0.05). The bone area showed significantly higher values in SLA and RBM compared to Machined surface 1st and 8th week and significantly higher values in SLA than Machined surface at the 4th week(p<0.05). Conclusion: The roughened surface of implants showed positive effect in the early stages of implantation and assisted in bone formation After the bone formation stage, there was no statistical difference between Machined and roughened surface groups. In dental implantation, where initial stability is critical to the success of implants, the use of roughened surface implants should assist in reducing the healing period after implantation.

• Restorative Dentistry and Endodontics
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• v.31 no.4
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• pp.263-268
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• 2006

Recently, self-etching adhesive system has been introduced to simplify the clinical bonding proce- dures. It is less acidic compared to the phosphoric acid, thus there is doubt whether this system has enough bond strength to enamel. The purpose of this study was to investigate the influence of additional etching on the adhesion of resin composite to enamel. Ninety extracted bovine permanent anterior teeth were used. The labial surfaces of the crown were ground with 600-grit abrasive paper under wet condition. The teeth were randomly divided into six groups of 15 teeth each. Clearfil SE $Bond^{\circledR},\;Adper^{TM}$ Prompt L-Pop and Tyrian $SPE^{TM}$ were used as self-etching primers. Each self-etching primers were applied in both enamel specimens with and without additional etching. For additional etching groups, enamel surface was pretreated with 32% phosphoric acid (UNI-ETCH, Bisco, Inc., Schaumburg, IL. USA). Hybrid resin composite Clearfil AP-X, (Kuraray Co., Ltd., Osaka, Japan) was packed into the mold and light-cured for 40 seconds. Twenty-four hours after storage, the specimens were tested in shear bond strength. The data for each group were subjected to independent t - test at p < 0.01 to make comparisons among the groups. In Clearfil SE $Bond^{\circledR}$, shear bond strength of additional etching group was higher than no additional etching group (p < 0.01). In $Adper^{TM}$ Prompt L-Pop and Tyrian SPE, there were no significant difference between additional etching and non-etching groups (p > 0.01). In conclusion, self-etching adhesive system with weak acid seems to have higher bond strength to enamel with additional etching, while self-etching adhesive system with strong acid seems not.