• Journal of Genetic Medicine
• /
• v.13 no.1
• /
• pp.46-50
• /
• 2016

Achondroplasia and hypochondroplasia are the two most common forms of short-limb dwarfism. They are autosomal dominant diseases that are characterized by a rhizomelic shortening of the limbs, large head with frontal bossing, hypoplasia of the mid-face, genu varum and trident hands. Mutations in the fibroblast growth factor receptor-3 (FGFR3) gene, which is located on chromosome 4p16.3, have been reported to cause achondroplasia and hypochondroplasia. More than 98% of achondroplasia cases are caused by the G380R mutation (c.1138G>A or c.1138G>C). In contrast, the N540K mutation (c.1620C>A) is detected in 60-65% of hypochondroplasia cases. Tests for common mutations are often unable to detect the mutation in patients with a clinical diagnosis of hypochondroplasia. In this study, we presented a case of familial hypochondroplasia with a rare mutation in FGFR3 identified by next generation sequencing.

• Korean Journal of Head & Neck Oncology
• /
• v.35 no.2
• /
• pp.61-65
• /
• 2019

Hamartomas are non-neoplastic malformations or congenital errors of tissue development. Hamartoma is composed by an excessive growth of mature tissue present in wrong proportions and abnormal arrangements. The lesion usually presents as a submucosal mass with ill-defined margins. Hamartoma occurs in all areas of the body, especially in the liver, spleen, kidney and lung. However, hamartoma is very rare in the head and neck. Presenting symptoms of hamartoma are typically vague and nonspecific. Treatment of hamartomas consists of adequate surgical excision. We present a 59 year-old male patient who presented with submental swelling. Malignancy could not be ruled out with preoperative radiologic examination, so surgical excision was planned. The mass was excised with transcervical approach. Histopathologic examination has confirmed the mass as a mucinous gland adenomatoid hamartoma.

• Journal of Environmental Science International
• /
• v.29 no.5
• /
• pp.541-549
• /
• 2020

In this study, standard precipitation index- based analysis associated with run theory was performed using 53 years' (1967-2019) precipitation data to investigate the meteorological drought in Chuncheon. The duration of the meteorological drought in Chuncheon was 8.06 months, magnitude of the drought was -8.21, and average drought depth was -1.08. The drought in May 2014 lasted 21 months until January 2016; the drought scale and average depth was -34.06 and -1.62, respectively. This was the most severe drought in Chuncheon. As a result of drought frequency analysis, the drought scale of May to December in 2014 was estimated to be -16.16, and the return period was estimated to be 300 years. These results are expected to further increase the magnitude and frequency of weather droughts caused by climate change. Therefore, it is critical to prepare appropriate structural measures.

• Journal of the Korean Society of Safety
• /
• v.37 no.6
• /
• pp.148-157
• /
• 2022

Every year, particularly during the monsoon rainy season, landslides at the Chuncheon province of South Korea cause tremendous damage to lives, properties, and infrastructures. More so, the high rainfall intensity and long rainfall days that occurred in 2020 have increased the water content in the soil, thereby increasing the chances of landslide occurrences. Besides this, the rainfall thresholds and characteristics responsible for the initiation of landslides in this region have not been properly identified. Therefore, this paper addresses the rainfall thresholds responsible for the initiation of landslides at Chuncheon from a regional perspective. Using data obtained from rainfall measurements taken from 2002 to 2011, we identify a threshold relationship between rainfall intensity and rainfall duration for the initiation of landslides. In addition, we identify the relationship between the rainfall intensity using a 3-day, 7-day, and 10-day antecedent rainfall observation. Specifically, we estimate the rainfall data at 8 sites where debris flow occurred in 2011 by kriging. Following this, the estimated data are used to construct the relationship between the intensity (I), duration (D), and frequency (F) of rainfall. The results of the intensity-duration-frequency (IDF) analysis show that landslides will occur under a rainfall frequency below a 2-year return period at two areas in Chuncheon. These results will be effectively used to design structures that can prevent the occurrence of landslides in the future.

• The Journal of the Society of Stroke on Korean Medicine
• /
• v.11 no.1
• /
• pp.89-98
• /
• 2010

This study was performed to investigate the effectiveness of trigger point needling and oriental medical treatment to shoulder pain patients in stroke sequelae with three aspects of pain and range of motion, muscle strength. Trigger point needling was applied to 3 patients on supraspinatus, infraspinatus, deltoid, subscapularis muscle. For evaluating treatment, visual analog scale(VAS), passive range of motion(PROM), muscle strength evaluation(MSE) were checked. After treatment, VAS score of 1 cases were decreased. PROM of 1 case was improved and MSE of 2 cases were improved slightly. These results suggest that trigger point needling and oriental medical treatment were effective on shoulder pain patients in stroke sequelae and it is necessary to research more case with shoulder pain in stroke sequelae.

• Journal of Korean Neurosurgical Society
• /
• v.49 no.4
• /
• pp.229-230
• /
• 2011

Visual loss is one of the ocular symptoms resulting from a carotid cavernous fistula (CCF), but has rarely been reported as the sole manifestation in CCF. Visual impairment is known to be associated with a poor outcome unless timely intervention is employed. Herein, the authors report a patient with bilateral rapid progressing visual loss as a sole manifestation in CCF. Vision was successfully restored by transarterial embolization. The authors discuss the necessity of urgent fistula obliteration in patients with visual loss.

• Journal of Korean Neurosurgical Society
• /
• v.54 no.6
• /
• pp.532-536
• /
• 2013

Charcot spine is a progressive and destructive process that affects the vertebral bodies, intervertebral discs, and posterior facets. It is the result from repetitive microtrauma in patients who have decreased joint protective mechanisms due to loss of deep pain and proprioceptive sensation, typically because of spinal cord injury. The objective of the study is to report an unusual case of Charcot spine, as a late complication of traumatic spinal cord injury, treated by a circumferential arthrodesis performed with a single staged posterolateral costotransversectomy approach.

• Journal of Korean Neurosurgical Society
• /
• v.58 no.5
• /
• pp.491-493
• /
• 2015

The upper trunk of the brachial plexus is the most common area affected by neuralgic amyotrophy (NA), and paresis of the shoulder girdle muscle is the most prevalent manifestation. Posterior interosseous nerve palsy is a rare presentation in patients with NA. It results in dropped finger on the affected side and may be misdiagnosed as entrapment syndrome or compressive neuropathy. We report an unusual case of NA manifested as PIN palsy and suggest that knowledge of clinical NA phenotypes is crucial for early diagnosis of peripheral nerve palsies.

• Journal of the Korean Institute of Rural Architecture
• /
• v.11 no.3
• /
• pp.19-28
• /
• 2009

This research aimed at showing an improvement direction in the future by analyzing the tendency to select a rural landscape housing and the characteristics centering around the data of the landscape-authenticated housing executed in Chuncheon City from 2005 to 2008. For 4 years, 25 houses in all were authenticated by Chuncheon City after being selected as landscape housing. As the result of analyzing the authenticated 25 housing, lots of landscape houses were located in natural green areas, and small-scale houses of $99m^2$ or less in the house size were preferred. The structures introducing the nature-friendly materials such as wood, yellow earth and clay continued to increase in the house structure. And in the selection of the authenticated houses, the landscape architecture and the harmony with the surrounding environment had a big effect on the selection.

• Clinics in Shoulder and Elbow
• /
• v.11 no.2
• /
• pp.185-188
• /
• 2008

Acromioclavicular joint injuries usually occur as a result of direct trauma to the superolateral aspect of the shoulder. Roockwood Type IV injuries are relatively uncommon, and they are easily misdiagnosed or neglected in patients who have suffered multiple traumas. Therefore, to correctly treat a patient with type IV injury, we need to take a careful physical examination and conduct proper radiologic evaluation for the acromioclavicular joint. We report here on two cases of modified Weaver-Dunn reconstruction for neglected type IV acromioclavicular joint injuries that were associated with multiple rib fractures.