• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7057-7063
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• 2013

The discovery of the immunodeficient mice has provided a tool for establishing animal models as hosts for in vivo analysis of AML. Various model systems have been established in the last few decades, and it is essential that murine AML models are developed to exploit more specific, targeted therapeutics. In this review, we concentrate on the models of AML and discuss the development of immunodeficiency models for understanding of leukemogenesis, describe those now available and their values and document the methods used for establishing and identifying AML mice models, as well as factors influencing engraftment of human AML in immunodeficient mice. Thus, the function of this article is to provide clinicians and experimentalists with a chronological, comprehensive appraisal of all AML model systems.

• Journal of Korean Society for Quality Management
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• v.44 no.1
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• pp.43-60
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• 2016

Purpose: This paper reviews the papers on TQM issues which are published in the Journal of the Korean Society for Quality Management (KSQM) since 1965. The literature review is purposed to survey a variety of TQM issues for several categories. Methods: We divide all of TQM issues into 6 categories: ISO system, quality assurance, quality management theory, empirical study on quality management, quality awards, and quality management etc. Results: Dividing all of papers on TQM published in KSQM for 50 years into 6 categories, we provide a chronological roadmap for individual categories, and summarize the contents and contributions of surveyed papers. Conclusion: The review paper is expected to provide future direction to improve TQM theories and applications in manufacturing and service industries.

• Journal of Korean Society for Quality Management
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• v.44 no.1
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• pp.17-28
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• 2016

Purpose: This paper reviews the papers on quality innovation issues which are published in the Journal of the Korean Society for Quality Management (KSQM) since 1965. The literature review is purposed to survey a variety of quality innovation issues Methods: We divide all of quality innovation issues into 2 categories: quality control circle, quality innovation and improvement Results: Dividing all of papers on quality innovation published in KSQM for 50 years into 2 categories, we provide a chronological roadmap for individual categories, and summarize the contents and contributions of surveyed papers Conclusion: The review paper is expected to provide future direction to improve quality innovation theory and practices in manufacturing and service industries

• International Journal of Knowledge Content Development & Technology
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• v.2 no.1
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• pp.37-49
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• 2012

This research aims to perform a contextual study of the wedding customs, wedding procedures, and wedding costumes included in Korean traditional wedding culture, making use of cultural contents which form cultural archetypes. The range of wedding customs studied are set limits from the Joseon dynasty to ancient times, and, for wedding procedures and costumes, to the Chosun dynasty, when a wedding ceremony became the norm. Only wedding ceremonies performed among ordinary classes are included as subjects for this research; wedding ceremonies and costumes for court are excluded. The cultural archetypes developed within these boundaries suggest prior cultural content, developed beforehand. The research methods are focused on document records inquiry and genre paintings during the Joseon era, using museum resources as visual materials. The following is the outcome of this research: Firstly, wedding customs and procedures observed among folk materials are presented in chronological order. Secondly, the brides' and grooms' wedding costumes are also presented chronologically, differentiated by class-characteristics.

• Nuclear Engineering and Technology
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• v.40 no.4
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• pp.251-254
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• 2008

Issues and themes concerned with nuclear power plant uprating are examined. Attention is brought to the fact that many candidate nuclear power plants for uprating have anyway been operated below their rated power for a significant part of their operating life. The key issues remain safety and reliability in operation at all times, irrespective of the nuclear power plant's chronological or design age or power rating. The effects of power uprates are discussed in terms of material aspects and expected demands on the systems, structures and components. The impact on operation and maintenance methods is indicated in terms of changes to the ageing surveillance programmes. Attention is brought to the necessity checking or revising operator actions after power up-rating has been implemented.

• Journal of Korean Society for Quality Management
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• v.44 no.2
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• pp.221-244
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• 2016

Purpose: This research reviews the papers, published in the Journal of the Korean Society for Quality Control (KSQC) and the Journal of the Korean Society for Quality Management (KSQM) since 1965, in the area of statistical methods. The literature review is performed in the four fields of the statistical methods and we categorize the published articles into the several sub-areas in each field. Methods: The reviewed articles are classified into the four main categories: probability model and estimation, Bayesian analysis and non-parametric analysis, regression and time series analysis, and application of data analysis. We examine the contents and relationships of the published articles of the several sub-areas in each category. Results: We summarize the reviewed papers in the chronological road-maps for each sub-area, and outline the relations of the connected papers. Some comments on the contents and the contributions of the reviewed papers are also provided in this paper. Conclusion: Various issues are employed and published on the research of the application statistical methods for past 50 years, and many worthy works are achieved in the theory and application areas of statistical methods for improving quality in the manufacturing and service industries. The future direction of the research in the statistical quality management methods also can be explored by the contents of this research.

• Archives of Plastic Surgery
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• v.38 no.6
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• pp.725-732
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• 2011

Purpose: Skin grafting is one of the most commonly used methods in reconstructive plastic surgery field, but complications such as color change, contracture or hypertrophy are common problems. However, pathophysiology of the color change after skin graft is not yet determined and no animal model is established. Methods: Full thickness skin grafts were performed on the dorsum of C57BL/6 mice. Serial chronological gross inspection for color change and pigmentation were examined. Melanin pigments were traced by Fontana-Masson staining and semi-quantitative analysis was performed. In addition, immunohistochemical staining of S-100, Micropthalmia related Transcription Factor (MITF) and Melan-A antibodies were also performed to observe melanocytes and their changes. Results: After skin graft, color change and pigment spots were observed in the graft. Fontana-Masson staining showed melanin pigments in the epidermal and dermal layers in all mice. Immunohistochemistry staining to S-100, MITF, Melan-A antibodies showed melanocytes at the basal layer of epidermis and dermis. Conclusion: In conclusion, we have established an animal model for skin pigmentation after skin graft. We believe this study may be useful in understanding of the behavior of melanocytes after skin graft.

• Proceedings of the Korean Geotechical Society Conference
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• 2010.03a
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• pp.198-207
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• 2010

Many methods and techniques have been developed to obtain the accurate design parameters in soft soils. In particular, several researchers suggest the techniques to get the void ratio for understanding the soil behavior. The objective of this paper verifies the accuracy of the proposed analytical solution for determining the void ratio based on the elastic wave velocities. The paper covers the theories of Wood, Biot, Gassmann and Foti proposed chronological order. The total theory represents the wave propagation in fully saturated medium. To verify the proposed analytical solution, the laboratory and field tests are carried out. After measuring the elastic wave, the void ratios are assessed using proposed equation. The volume based void ratios are also obtained for comparing with the estimated value by several equations. The values estimated by volume, Gassmann and Biot are show good similarity. However, the void ratios based on Wood and Foti methods have a slightly different trend. This study suggests that the theories of Biot and Gassmann may be a useful equation for assessing the void ratio using elastic wave velocities in the field.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.4
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• pp.1591-1597
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• 2015

Background: Korea has experienced rapid economic development in a very short period of time. A mixture of traditional and modern risk factors coexists and the rapid change in non-genetic factors interacts with genetic constituents. With consideration of these unique aspects of Korean society, a large-scale genomic cohort study-the Health Examinees (HEXA) Study-has been conducted to investigate epidemiologic characteristics, genomic features, and gene-environment interactions of major chronic diseases including cancer in the Korean population. Materials and Methods: Following a standardized study protocol, the subjects were prospectively recruited from 38 health examination centers and training hospitals throughout the country. An interview-based questionnaire survey was conducted to collect information on socio-demographic characteristics, medical history, medication usage, family history, lifestyle factors, diet, physical activity, and reproductive factors for women. Various biological specimens (i.e., plasma, serum, buffy coat, blood cells, genomic DNA, and urine) were collected for biorepository according to the standardized protocol. Skilled medical staff also performed physical examinations. Results: Between 2004 and 2013, a total of 167,169 subjects aged 40-69 years were recruited for the HEXA study. Participants are being followed up utilizing active and passive methods. The first wave of active follow-up began in 2012 and it will be continued until 2015. The principal purpose of passive follow-up is based on data linkages with the National Death Certificate, the National Cancer Registry, and the National Health Insurance Claim data. Conclusions: The HEXA study will render an opportunity to investigate biomarkers of early health index and the chronological changes associated with chronic diseases.

• Korean Journal of Culture and Social Issue
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• v.13 no.1
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• pp.91-114
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• 2007

This study was performed to decide how to do research and resolve on mental health problems of the people after reunification, which is recognized as ultimately important issue. At first we analyzed the case of Germany. To do so, we reviewed the existing research, which included various issues such as reunification for the Germans, chronological research flow analysis, the issues of mental health, research methods for mental health problems, therapy for mental health problems and so on. And then we sought the ways to connect research for the North Korean defectors and unification era, and suggested the several research orientation and methods for mental health study of the unification period.