• Title/Summary/Keyword: choroid plexus papilloma (CPP)

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Spinal Drop Metastasis from a Posterior Fossa Choroid Plexus Papilloma

  • Ahn, Soon-Seob;Cho, Young-Dae
    • Journal of Korean Neurosurgical Society
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    • v.42 no.6
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    • pp.475-477
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    • 2007
  • Choroid plexus papillomas (CPPs) are typically considered as benign tumors, with a favorable long-term prognosis. Drop metastasis of CPP into the spinal subarachnoid space is rare. We report a 42-year-old woman who presented with headache and back pain 6 years after removal of a posterior fossa CPP. Magnetic resonance imaging revealed mass lesions in the lumbosacral subarachnoid space and recurrent intracranial tumor. The lesions were resected and histologically diagnosed was CPP. We consider that CPP can spread via cerebrospinal fluid pathways and cause spinal drop metastasis. Therefore, it is necessary to evaluate the whole spinal axis and to perform periodic follow-up examinations in patients with CPP.

An Atypical Choroid Plexus Papilloma Initially Manifestating as Radicular Symptoms (방사성 증상이 초기 증상으로 나타난 비정형 맥락막 신경총 유두종)

  • Lee, Cheol-Jae;Kim, Jun-Hyung;Kim, Yunhee;Lee, Jang-Bo;Ryu, Byungju
    • Clinical Pain
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    • v.20 no.1
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    • pp.39-42
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    • 2021
  • A 29-year-old woman had 1-month history of back pain radiating into lower extremities, motor weakness, and sensory abnormalities in both lower extremities. Contrast-enhanced spinal magnetic resonance imaging (MRI) revealed a homogeneously enhancing mass at the T12~L1 and several intradural enhancing nodular lesions at L2~S1. Tumor resection surgery was performed and following histological examination showed that the tumor satisfied the diagnostic criteria for atypical choroid plexus papilloma (CPP). To find primary tumor sites, contrast-enhanced brain MRI, whole spine MRI, and PET-CT were carried out and additional lesions were detected at the fourth ventricle, right cerebellum, and upper thoracic spinal cord. This is a very rare case of metastatic atypical CPP that involves brain, upper thoracic spinal cord, and cauda equina with initial manifestation of radicular symptoms without clinical signs of primary brain lesion.

Long-term Chemotherapy with Lomustine Plus Hydroxyurea for Choroid Plexus Papilloma in a Schnauzer Dog

  • Jung, Dong-In;Song, Joong-Hyun;Jung, Hae-Won;An, Su-Jin;Hwang, Tae-Sung;Lee, Hee-Chun;Sur, Jung-Hyang;Cho, Kyu-Woan
    • Journal of Veterinary Clinics
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    • v.34 no.2
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    • pp.94-97
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    • 2017
  • A 10-year-old male Schnauzer dog presented with a 1-week history of ataxia, right-sided hemiparesis, and right-sided head tilt. On the basis of magnetic resonance imaging (MRI) with neurological examination and cerebrospinal fluid analysis results, a primary brain tumor was suspected. Therapy with imatinib mesylate plus hydroxyurea for 7 weeks was not effective and clinical signs worsened. Chemotherapy was then changed to lomustine plus hydroxyurea. Although the existing clinical signs continued, they did not deteriorate. No change in mass size was observed in subsequent MRI. The subject suddenly died from dyspnea 388 days after initial presentation. In this case, choroid plexus papilloma was definitively diagnosed based on histopathological findings.