• 제목/요약/키워드: cheongsimyeonja-tang

검색결과 31건 처리시간 0.015초

청심연자탕(淸心蓮子湯) 수추출물(水抽出物)이 XO/HX에 의해 손상(損傷)된 배양(培養) 해마신경세포(海馬神經細胞)에 미치는 영향(影響) (Effects of Cheongsimyeonja-tang water extract on the Cultured Primary Hippocampal Cell Damaged by XO/HX)

  • 이재흥;김형순;배영춘;김경요;원경숙;황승연
    • 사상체질의학회지
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    • 제14권3호
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    • pp.132-145
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    • 2002
  • The purpose of this study is to examine the toxic effects caused by xanthine oxidase/hypoxanthine(XO/HX) and the effects of herbal extracts such as Cheongsimyeonjatang(CYT) on the treatment of the toxic effects. For this purpose, experiments with the cultured hippocampal cells from new born mice were done. The results of these experiments were as follows. 1. XO/HX, a oxygen radical-generating system, decreased the survival rates of the cultured cells on MTT assay and NR assay, protein synthesis, and amounts of neurofilaments. 2. CYT have the efficacy of increasing protein synthesis decreased by XO/HX. 3. CYT have the efficacy. of increasing the amount of neurofilaments decreased by XO/HX. From the above results, it is suggested that Cheongsimyeonjatang (CYT) have marked efficacy as a protection for the damages caused by the XO/HX-mediated oxidative stress.

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