• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2003년도 생물공학의 동향(XIII)
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• pp.79-83
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• 2003

Standard terms on biotechnology, bioprodutcs and related services are essential for clear and consistent communications and information exchange among peoples working in the area of biotechnology and bioindustry. The standardization of biotechnology terms are prerequisite to any other standardization efforts in the area. The major objective of this project is to develop a comprehensive and advanced terminology platform for the legislation of KS codes for the domestic bioindustry by data mining from various sources.

• 생약학회지
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• 제36권2호통권141호
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• pp.65-69
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• 2005

The extract contents of various Phellinus species (Hymenochaetaceae) including P. linteus, P. baumii, P. pini and P. igniarius of domestic and foreign products, were examined to standardize the quality of these products. The differences of various extract contents were identified and compared between different species of Phellinus products. The thin layer chromatographic patterns were also analyzed and six unidentified samples were thought to originate from P. baumii and P. igniarius. The chemical standardization for the quality control of various origins could be suggested by this study.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2017년도 춘계학술대회 논문집
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• pp.85-85
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• 2017

ISO (International Organization for Standardization) is an independent, non-governmental international organization with a membership of 163 national standards bodies (NSB). The ISO standards are developed and processed within the technical committees (TC) or their subcommittees (SC) dealing with the different subject matters. The first technical committee, ISO/TC1, deals with screw threads and was created back in 1947. While, more recently, TC 309 was created to standardize organizational governance. The ISO technical committee in the field of metallic coatings was created in 1962 with the title ISO/TC107- Metallic and other inorganic coatings. This ISO/TC107 technical committee is dealing with the standardization of the characteristics of protective and decorative metallic coatings applied by electrolysis, fusion, vacuum or chemical means, mechanical deposition and ion plating. similarly, it also covers the standardization of the characteristics of protective and decorative non-metallic coatings (excluding paints and other organic coatings) on metal surface applied by electrolysis, fusion, vacuum or chemical means. Scope is further extended to the Standardization of the preparation of the substrates prior to the deposition of metallic and inorganic coatings. There are a total of 144 existing ISO standards published by this technical committee and has 19 participating countries (P-members) and 24 observing countries (O-members). Korean Agency for Technology and Standards (KATS), being the secretariat of ISO/TC107, is constantly supporting this technical committee for the development of standards and related activities.

• Journal of Ginseng Research
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• 제42권3호
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• pp.270-276
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• 2018

Background: Notoginsenoside Ft1 is a promising potential candidate for cardiovascular and cancer disease therapy owing to its positive pharmacological activities. However, the yield of Ft1 is ultralow utilizing reported methods. Herein, an acid hydrolyzing strategy was implemented in the acquirement of rare notoginsenoside Ft1. Methods: Chemical profiles were identified by ultraperformance liquid chromatography coupled with quadruple-time-of-flight and electrospray ionization mass spectrometry (UPLC-Q/TOF-ESI-MS). The acid hydrolyzing dynamic changes of chemical compositions and the possible transformation pathways of saponins were monitored by ultrahigh-performance LC coupled with tandem MS (UHPLC-MS/ MS). Results and conclusion: Notoginsenoside Ft1 was epimerized from notoginsenoside ST4, which was generated through cleaving the carbohydrate side chains at C-20 of notoginsenosides Fa and Fc, and vinaginsenoside R7, and further converted to other compounds via hydroxylation at C-25 or hydrolysis of the carbohydrate side chains at C-3 under the acid conditions. High temperature contributed to the hydroxylation reaction at C-25 and 25% acetic acid concentration was conducive to the preparation of notoginsenoside Ft1. C-20 epimers of notoginsenoside Ft1 and ST4 were successfully separated utilizing solvent method of acetic acid solution. The theoretical preparation yield rate of notoginsenoside Ft1 was about 1.8%, which would be beneficial to further study on its bioactivities and clinical application.

• 한국포장학회지
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• 제13권2호
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• pp.43-50
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• 2007

The production, distribution, and consumption of Korean medicinal herbs have increased every year because of an increase of health considerations. But there are no sufficient standardization procedures in packaging and distribution systems related to these herb products. The standardization of packaging material and dimension could be a good addition for establishing proper quality control methods for Korean medicinal herbs. Medicinal herbs deteriorate under physical, chemical and biological hazards such as oxidation, textural change under high moisture content, color change by light, sanitation problems by insect invasion and contamination. Packaging standardization with proper functional packaging materials is critical to ensure the qualities of medicinal herbs. Also, storage and distribution efficiencies can be improved by achieving packaging dimension standardization. This review summarizes recent research trends related to quality evaluation methods and major quality deterioration factors of Korean medicinal herbs. This paper also offers reviews on some of problems and challenges in current packaging and distribution systems of medicinal herb industries and briefly suggests advanced quality control methods through packaging standardization.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2015년도 추계학술대회 논문집
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• pp.134-134
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• 2015

• 문화기술의 융합
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• 제3권3호
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• pp.43-49
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• 2017

본 연구는 중소기업의 정보화를 추진함에 있어, 정보화 중에서도 중단기적인 도입 성과를 낼 수 있는 생산정보관리시스템 구축을 위하여, 화학제조업 분야의 핵심 업무 프로세스에 대하여 표준화를 연구하고 그에 따른 생산정보관리시스템을 구축 적용하는데 제공하고자 한다. 화학제조업 생산정보관리시스템 표준화를 위한 개발방법론은 중소기업기술정보진흥원에서 기 연구 개발된 생산정보관리시스템 개발 방법론(PSDM)을 적용하며, 표준화 대상은 시스템 구성도, 업무절차 흐름도, Menu Structure 등과 같이 시스템구축 시 골격이 되는 핵심 업무 프로세스이다. 본 연구로 생산정보관리시스템을 구축하고자 하는 화학제조업 중소기업 및 관련 전문 IT업체들이 표준화된 핵심 업무 프로세스를 적용하여 시스템을 보다 효과적으로 구축 할 수 있으며, 시스템에 대한 구축 용이성과 신뢰성을 제공하며 아울러 핵심 업무 프로세스의 활용이 극대화되기 위해서 사후관리 교육훈련 및 유지보수 방안도 제시하고 있다. 본 연구 결과를 적용함으로써 생산 공정의 불합리한 요소제거, 생산제품 품질 향상, 생산비용절감이 가능하다.

• 한국화재소방학회:학술대회논문집
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• 한국화재소방학회 1999년도 추계학술발표회 논문 초록집
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• pp.28-33
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• 1999

• Journal of Ginseng Research
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• 제43권3호
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• pp.377-384
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• 2019

Background: Inflammation is widespread in the clinical pathology and closely associated to the progress of many diseases. Triterpenoid saponins as a key group of active ingredients in Panax notoginseng (Burk.) F.H. Chen were demonstrated to show antiinflammatory effects. However, the chemical structures of saponins in the leaves and stems of Panax notoginseng (PNLS) are still not fully clear. Herein, the isolation, purification and further evaluation of the antiinflammatory activity of dammarane-type triterpenoid saponins from PNLS were conducted. Methods: Silica gel and reversed-phase C8 column chromatography were used. Furthermore, preparative HPLC was used as a final purification technique to obtain minor saponins with high purities. MS, NMR experiments, and chemical methods were used in the structural identifications. The antiinflammatory activities of the isolated saponins were assessed by measuring the nitric oxide production in RAW 264.7 cells stimulated by lipopolysaccharides. Real-time reverse transcription polymerase chain reaction was used to measure the gene expressions of inflammation-related gene. Results: Eight new minor dammarane-type triterpene oligoglycosides, namely notoginsenosides LK1-LK8 (1-8) were obtained from PNLS, along with seven known ones. Among the isolated saponins, gypenoside IX significantly suppressed the nitric oxide production and inflammatory cytokines including tumor necrosis $factor-{\alpha}$, interleukin 10, interferon-inducible protein 10 and $interleukin-1{\beta}$. Conclusion: The eight saponins may enrich and expand the chemical library of saponins in Panax genus. Moreover, it is reported for the first time that gypenoside IX showed moderate antiinflammatory activity.

• 한국가스학회지
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• 제22권5호
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• pp.1-17
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• 2018

태안반도 원유 유출사고, 구미 불산누출사고 등 2000년 전후로 하여 환경관련 사건과 사고가 빈번히 발생하고 있다. 이러한 환경오염사고를 계기로 선제적 대응 방안이 필요하다는 사회적 공감대가 형성되어 2014년 환경오염피해 배상책임 및 구제에 관한 법률이 제정되고, 2016년 1월부터 시행되고 있다. 이에 따라 도입된 환경책임보험제도는 국내 보험산업계에서 환경위험을 관리하는 새로운 보험모델의 표준화 정립을 통해 관리될 필요가 있다. 지금까지 보험산업에서 표준화에 대한 노력은 다양한 위험 유형의 보장성 보험모델들의 출현에 따라 진행되어 왔다. 이에 따라 본 연구에서는 지식 기반 서비스 중의 하나인 보험 영역에서 기업에 의해 발생 가능한 대기, 수질, 화학, 폐기물, 해양, 토양 등의 환경오염 발생에 대해 6가지 보장 매체에 관한 검증 자료를 의미적 상호운용이 가능한 온톨로지를 통해 표현하였으며, 사업장의 인허가를 토대로 보험 가입 매체 간의 관계를 추론하여 보험모델을 설계하고 제시하였다. 각 사업장 담당자에 의한 물질량 정산 과정과 검증자를 통한 정산결과의 편차를 줄이기 위해, 추상적인 개념을 흐름도로 객관화, 구체화 하였으며, 해마다 많은 비용과 소모되는 자원을 줄이기 위해 온톨로지 기반의 의사결정지원 시스템의 향후 구축 방안을 제시하고 일부 구현 하였다. 이를 통해 물질량 검증 기준을 표준화함으로써 오류를 최소화하고, 검증에 소요되는 시간과 자원을 감소시킬 수 있을 것으로 기대된다.